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source metabolism and function of cysteine and glutathione in the central nervous system

báo cáo hóa học:

báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx

Hóa học - Dầu khí

... around inflammatory foci in the spinal cord of rats with EAE, thus identifying potential determinants for trafficking of these cells to the CNS These findings are discussed in relation to therapeutic ... areas of the spinal cord displaying focal inflammation and demyelination (Fig 2E) Quantification of CCR1, CCR2 and CCR5 mRNAexpressing cells in relation to the stage of demyelinating activity The ... immunization) of EAE show extensive inflammation involving the white and grey matter (D), with marked demyelination in the inflammatory areas (F) The majority of the infiltrating inflammatory...
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Báo cáo sinh học:

Báo cáo sinh học: "Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system" doc

Báo cáo khoa học

... treatment, there was a 2.5-fold increase in apoptosis in the subventricular zone (SVZ) and a 4-fold increase in the dentate gyrus of the hippocampus (DG) The increased cell death persisted in the SVZ and ... demyelinated axons, including partial or complete loss of myelin sheaths and increases in inter-laminar splitting of the myelin sheaths Analysis of transverse sections (Figure 9) provided further ... decreased levels of MBP in the CC and in the white-matter tracts of the striatum of treated animals (Figure 10) In agreement with the majority of the cell bodies in the mature CC belonging to oligodendrocytes...
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Báo cáo khoa học:

Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx

Báo cáo khoa học

... nNOS and iNOS in neurons increased when bacterial encephalitis occurred This is the first study of NOS expression in the goat brain with listeriosis The involvement of iNOS in bovine and caprine ... brainstem and the staining pattern was similar to those of control brains with nonneurological diseases In the microabscesses, iNOS was recognized in inflammatory cells (mainly macrophages) in the ... hematoxylin Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervous system of goat Enhanced expression of nNOS and iNOS in L monocytogenes-infected...
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Specificity and diversity in the vertebrate nervous system  an analysis of two genes

Specificity and diversity in the vertebrate nervous system an analysis of two genes

Cao đẳng - Đại học

... in the study of the role of EphrinB2 in vivo EphrinB2 expression has been detected in the visual system in other organisms The aim of this project was to study the expression pattern of EphrinB2 ... guidance at the midline, Eph-Ephrins are also involved in creating patterned neuronal connections in the CNS and the peripheral nervous system Similar to the topographic mapping in the visual system, ... target neurons in the tectum The Recombination activating gene-1 (RAG1) is expressed in the vertebrate immune system and in the nervous system, including the zebrafish visual system (Chun et...
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báo cáo khoa học:

báo cáo khoa học: "In vivo observation of gold nanoparticles in the central nervous system of Blaberus discoidalis" potx

Báo cáo khoa học

... nAuNPs in the cockroach’s brain and to study the interactions between nAuNPs and the brain tissue: hyperspectral Page of imaging, XPS, confocal microscopy, and TEM imaging The Hyperspectral imaging ... identify the organs affected by the nAuNPs The XPS was used to verify the presence of nAuNPs embedded in the brain tissue The confocal microscope and TEM were used to gain insights into the interaction ... eliminated by using only young males in this study The effects of temperature, humidity, and wind were diminished by maintaining them in a controlled environment However, the fluctuations in Rocha...
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The role of hydrogen sulfide in the central nervous system implications in the treatment of alzheimers disease

The role of hydrogen sulfide in the central nervous system implications in the treatment of alzheimers disease

Kỹ thuật - Công nghệ

... neurotransmitter in the brain The interaction of glutamate with the N-methyl-D-aspartate (NMDA) receptor is important in the workings of memory and learning In AD an increase in glutamate activity results in ... targeting cerebral amyloid generation in AD They either inhibit the production of Aβ or escalate its clearance in the brain The most common mechanisms of action of these drugs are the inhibition of ... like tau is involved in microtubule assembly It serves as a binding for the tubulin Mutations in α-synuclein lead to loss of this binding ability, resulting in tubulin and α-synuclein aggregation...
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INVESTIGATION OF MEMBRANE PROPERTIES IN THE CENTRAL NERVOUS SYSTEM OF DROSOPHILA MELANOGASTER STUDIED BY FLUORESCENCE CORRELATION SPECTROSCOPY

INVESTIGATION OF MEMBRANE PROPERTIES IN THE CENTRAL NERVOUS SYSTEM OF DROSOPHILA MELANOGASTER STUDIED BY FLUORESCENCE CORRELATION SPECTROSCOPY

Cao đẳng - Đại học

... be studied using FCS These intensity fluctuations contain information which can be extracted by analysing the rates and the amplitudes of the intensity fluctuations and subjecting them to an autocorrelation ... catalyzes the hydrolysis of ceramide to sphingosine Ceramide is the simplest form of sphingolipid and was shown to promote clustering of nanoscale domains in supported lipid bilayers [46] and in cells ... also given Chapter introduces the concepts and theory of FCS as well as the experimental setup of this instrument The calibration of the FCS system is also discussed The last part of this chapter...
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Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

Báo cáo khoa học

... discovery of a brain-specific MT isoform, GIF, in 1991, sparked considerable interest in understanding the role of all MTs in the brain, and particularly within the injured or diseased brain In the ... studies examining the role of GIF in AD, linked to its initial discovery as a factor deficient in the AD brain There remains no clear consensus on the role of GIF in the pathogenesis of AD, and therefore ... whether GIF acts in a neuroinhibitory manner when administered directly into the brain following traumatic brain injury In one such study, the injection of GIF into the site of a stab wound promoted...
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Workshop Training Manual:

Workshop Training Manual: " Technologies for improving goat housing and hygiene in the central provinces of Vietnam " ppt

Báo cáo khoa học

... Highlands, 8.9% for the Central Coast, and 2.1-3% for the Southeastern and the Southwestern) Goats in the Northern moutainous areas make up 48% of the country, and 67% of the North Most of them ... another, unlike the destructive gobbling nature of the cows In the other hand, goat helps to prevent the weeds and fertilize the plants with its excrement • Lack of experience is one of the main ... contamination and plague spreading still lingers around 3) Help the goats regain their strength by sufficient feeding and mineral and vitamine supplement 4) In case of diarrhoea, drinking water and salt...
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báo cáo khoa học:

báo cáo khoa học: "Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature" pdf

Báo cáo khoa học

... described the MRI features GL provided the pathological diagnosis TJ was the surgeon and gave the final approval of the version to be published Competing interests The authors declare that they have ... angiitis of the central nervous system: initial and follow-up MR features Neuroradiology 2009, 51:651-659 12 Ay H, Sahin G, Saatci I, Söylemezoğlu F, Saribaş O: Primary Angiitis of the Central Nervous ... central nervous system: serial MRI of brain and spinal cord Neuroradiology 2001, 43:599-607 14 Moore PM: Diagnosis and management of isolated angiitis of the central nervous system Neurology...
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Báo cáo y học:

Báo cáo y học: " Molecular analysis of HBV genotypes and subgenotypes in the Central-East region of Tunisia" potx

Báo cáo khoa học

... NH and OB conceived of the study, participated in its design, and in drafting the manuscript HT and JB participated in the study design and coordination and in discussing manuscript NH, NBF and ... using the Neighbor-Joining method The evolutionary distances were computed using the Maximum Composite Likelihood method and are in the units of the number of base substitutions per site There ... resulted in an additional fragment of 160 pb The presence of the same site of restriction in this region of genotype D strains was also observed in sequences available in GenBank under the following...
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Báo cáo khoa học:

Báo cáo khoa học: "The concentration of oxygen, lactate and glucose in the central veins, right heart, and pulmonary artery: a study in patients with pulmonary hypertension" ppt

Báo cáo khoa học

... refutes the idea of mixing SVC and IVC blood as the mechanism for development of Δ[Lac] The finding of greater SO2 and [Lac] in IVC and SVC than in pulmonary artery indicates that further dilution of ... position of the catheter at each sampling site and the blood sampling procedure was performed within a span of min, with no changes noted in heart rate or blood pressure in any of the patients Finally, ... answered by further clinical studies Conclusion The development of ΔSO2 and Δ[Lac] in the patient population studied cannot be explained by the mixing of SVC and IVC blood The development of these gradients...
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STATE MANAGEMENT OF SOCIALISATION OF FOREST PROTECTION AND DEVELOPMENT IN THE CENTRAL HIGHLANDS OF VIET NAM

STATE MANAGEMENT OF SOCIALISATION OF FOREST PROTECTION AND DEVELOPMENT IN THE CENTRAL HIGHLANDS OF VIET NAM

Tổng hợp

... SFPD in the Central Highlands; - Perfecting organisation and operation of state management of SFPD in the Central Highlands; - Enhancing inspection, monitoring, and supervision of SFPD in the Central ... Conducting close inspection and control of converting forestry land into other purposes; - Enhancing measures of inspection, monitoring, and supervision; - Directing and implementing inspection and ... protection and development in the Central Highlands Objects and Scopes of the Study The objects of the dissertation include both theoretical and practical issues of state management of socialization of...
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Genetic engineering and surface modification of baculovirus derived vectors for improved gene delivery to the central nervous system

Genetic engineering and surface modification of baculovirus derived vectors for improved gene delivery to the central nervous system

Cao đẳng - Đại học

... within the cell is reverse transcribed into double-stranded DNA which can then integrate randomly into the host cell genome The use of retrovirus vectors for gene delivery to the nervous system ... to achieve the optimized infection condition and enhance the virus replicating efficiency, we investigated the relationship between the amount of input virus and the yield of resulting replicated ... human body, in which case they are more controllable and have reduced risk in the gene therapy applications In the following section, one type of viral vectors derived from the insect origin, namely...
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Development of hybrid promoters and viral vectors for improved gene delivery to the central nervous system

Development of hybrid promoters and viral vectors for improved gene delivery to the central nervous system

Thạc sĩ - Cao học

... major functional cells in the nervous system, carrying out the fundamental tasks of receiving, conducting and transmitting signals Therapeutic protection of these cells is one of the main goals of ... one of the key issues of gene therapy The expression level and specificity of the therapeutic gene is primarily determined by the activity of the promoter at the transcriptional level, and the ... between the sites of Not I and Xba I Luciferase was used as the reporter gene for all the constructions and was inserted into the downstream of the promoters, between the sites of Xho I and Hind...
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STUDY OF RELATION BETWEEN ECONOMIC GROWTH AND INEQUALITY IN THE CENTRAL VIETNAM KEY ECONOMIC REGION

STUDY OF RELATION BETWEEN ECONOMIC GROWTH AND INEQUALITY IN THE CENTRAL VIETNAM KEY ECONOMIC REGION

Tổng hợp

... inequality of income and income inequality has been seen as important cause of the problem of social inequality in general Income inequality is both the cause and a result of other forms of inequality ... Status of income inequality in the region and the provinces here have increased continuously from 2001 to 2013, and the gap of income inequality tend to widening according to the growth process Income ... observations in the data space, in order to avoid violating the assumptions of the model Methods of analysis and evaluation of the impact of income inequality to economic growth: The thesis has select the...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Subgrammars, Rule Classes and Control in the Rosetta Translation System" ppt

Báo cáo khoa học

... (basic meanings) the meaning of the rules (rule m e a n i n g s ) In Montague Grammar these meanings are expressed in intensional logic In the Rosetta system the meanings of rules and basic expressions ... on the one hand and by the notion projection from X-theory on the other hand The second problem was that there is no way of explicitly controlling the application of rules in free Mgrammars and ... XPPROP and C L A U S E ) The fact that in X-theory the phrase markers of the resulting constituents are In the example of the smart girl / the girl that is 8mart the subgrammars for the projection...
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Báo cáo khoa học:

Báo cáo khoa học: " Experimental concepts for toxicity prevention and tissue restoration after central nervous system irradiation" ppt

Báo cáo khoa học

... Schematicin cancer of the time of the central nervous system Figure (CNS) via portals exposing some part course of radiation-induced Schematic concept of the time course of radiation-induced reactions ... phase where chemokines, cytokines and growth factors play important roles in intra- and intercellular communication CNS radiotherapy induces the production of inflammatory cytokines and mediators ... neurons), stem and progenitor cells and the vascular system, also resulting in important alterations of the local microenvironment [9] The latent time preceding the clinical manifestation of damage...
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Implementing legislation on democracy in communes, wards and towns in the central highlands

Implementing legislation on democracy in communes, wards and towns in the central highlands

Tổng hợp

... and towns in the Central Highlands provinces - Analyze, assess the status of implementation of the law of democracy in communes, wards and towns in the provinces of the Central Highlands in the ... wards and towns in the provinces of the Central Highlands 3.2.1 The specific factors affecting the implementation of the law of democracy in communes, wards and towns in the provinces of the Central ... and towns in the provinces of the Central Highlands From the analysis of theoretical basis and practical implementation of the law of democracy in communes, wards and towns in the provinces of...
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Báo cáo sinh học:

Báo cáo sinh học: "The long term effects of chemotherapy on the central nervous system" docx

Báo cáo khoa học

... with certain brain tumors, especially for the very young Because of the rapid myelinization that occurs in infants, the finding by Noble and colleagues [1] of the adverse effects of chemotherapy ... radiation The response of investigators has been to reduce the dose and/ or volume of radiation and, in some cases, to eliminate radiation entirely, adding combination chemotherapy to the treatment ... Abnormal CT scans of the brain in asymptomatic children with acute lymphocytic leukemia after prophylactic treatment of the central nervous system with radiation and intrathecal chemotherapy N Engl...
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