... the moment ofthecontraction Under these circumstances the effects ofthe changes ofthe acceleration ofthe load on thecontraction can be traced Effect ofthe acceleration ofthe load on the ... acceleration ofthe load slows down the pre-steady state ofthecontraction Methods The evaluation ofthe effect of load acceleration on the pre-steady state ofmuscle fibre contraction was made on the ... power output andthe experimental speed ofcontractionThe result is that by decreasing the acceleration ofthe load the value ofthe constant, 1/k (s-1), decreases andthe time length ofthe pre-steady...
... involves the ubiquitin proteasome pathway (UPP) andthe autophagy (lyso somal), caspase, cathepsin andthe calcium-dependent calpain pathways The individual prominence of each of these pathways in muscle ... patients, including study ofthe UPP and autophagy systems, we sought to carry out both targeted and global molecular profiling in theskeletalmuscleof cancer patients and relate our findings ... subjects Due to the small number of controls (otherwise con idered s as non-cancer patients but with other co-morbidities) andthe lack of detailed knowledge of their physical capacity, the primary...
... result is shown (top) The bottom panel shows the results of real-time PCR analysis ofthe mRNA expression of PRiMA I and AChET (C) Samples of extracts from the lower leg muscles of rat (birth to adult ... from the peak area, relative to the area ofthe entire sedimentation profile, and its activity was given by the product of this proportion with the total AChE activity The amount of G4 AChE in muscle ... NMJs, we analyzed the effect of denervation on the localization of PRiMA The NMJs ofthe denervated tibialis and sham-operated muscle were stained for PRiMA, together with the postsynaptic marker...
... < 0 In the next statement, we use the relationship between the first phase ψ andthe second phase ofthe basis x , y of symplectic system S andthe fact that the behavior ofthe u v first and second ... phases ofsystem S plays the crucial role in counting generalized zeros of solutions of symplectic system S andof its reciprocal system Sr Theorem 3.4 If system S with the sequences bk / and ck ... introduce the definition ofthe first phase of any basis ofthesystem S , and we establish a formula for the forward difference of this phase We apply this formula to study the relationship between S and...
... functions ofthe external muscle layers are mixing, storage and propulsion ofthe colon contents Mixing ofthe chyme within the colon occurs through segmenting contractions ofthe circular smooth muscle ... responsible for the majority of motility in the colon The muscularis mucosae is located at the border between the mucosal and submucosal layers, and promotes movement ofthe epithelial mucosa The main ... direct the expression ofthe two isoforms ofthe 220-kDa MLCK that differ from each other only in the sequence encoded by exon 1* ofthe 220-kDa MLCK E1* The protein produced from usage of exon...
... in the classification ofthe genetic species of Aeromonas andthe evaluation of potential virulence properties I.4 Genomic islands and pathogenicity islands Genomic islands (GIs) are part of ... persistently and to evade the host’s immune response, thus contributing to the disease process There are significant differences between the role ofthe S-layer of A salmonicida (vapA) and that of A ... Buchrieser et al., 1998) The majorities ofthe clusters located within GIs are useful for the survival and transmission ofthe microbes and provide a selective advantage to the island-carrying organisms...
... for further reduce the power consumption of wearable ECG system in the future Chapter concludes the work The Wireless ECG plaster of this work was accepted by the Biomedical Circuits and Systems ... The asynchronous core ofthe proposed design is synthesized in the Balsa framework using the dual-rail four-phase approach Furthermore, the core’s structure adopts No pipeline structure together ... Holter systems are often bulky with many wires stuck on patient’s chest The operational life ofthe Holter is usually limited within 24 hours, and ECG data are analyzed offline for diagnosis of the...
... for further reduce the power consumption of wearable ECG system in the future Chapter concludes the work The Wireless ECG plaster of this work was accepted by the Biomedical Circuits and Systems ... The asynchronous core ofthe proposed design is synthesized in the Balsa framework using the dual-rail four-phase approach Furthermore, the core’s structure adopts No pipeline structure together ... Holter systems are often bulky with many wires stuck on patient’s chest The operational life ofthe Holter is usually limited within 24 hours, and ECG data are analyzed offline for diagnosis of the...
... technique together with the gastric fundus and cardia using the retroperitoneal fat and parts ofthe left column ofthe diaphragm for covering the residual mass and as resection margin The postoperative ... mobilisation ofthe greater and lesser curvature and opening ofthe lesser sac, the tumor could be mobilized easily from the pancreas as well as from the splenic hilus Through mobilisation ofthe distal ... regression of tumor possible now with preservation ofthe distal stomach andthe spleen Operation Intraoperatively the tumor was found to be located dorsal ofthe GEJ The diaphragm was incised and after...
... has the advantage of providing a full specimen for histological examination and for the diagnosis ofthe extent and infiltration depth ofthe lesion The outcome of endoscopic therapy can therefore ... gastroesophageal junction (B) The middle esophagus The iatrogenic ulcers in the esophagus and EGJ resulting from the EVL were treated with the administration of a proton pump inhibitor and sodium alginate The ... examination andthe diagnosis ofthe extent and infiltration depth ofthe lesion cannot be evaluated Conclusion We believe that because of its technical simplicity and safety, endoscopic therapy...
... and 71 Considering the location ofthe N-terminal extremity of DNter2 on the structure of CARP andthe presence ofthe potential cleavage sites, we identified the localization ofthe cleavage site ... together with respect to their common minimal structure and their potential role in the control of transcription [17,19–21] Although the three MARPs are expressed in both heart andskeletalmuscle ... identified as a partner ofskeletalmuscle titin-N2A [18] An analysis of CARP expression in the subcellular compartments Regulation of CARP by calpain obtained from themuscleofthe mice injected...
... understanding ofthe anatomy and function ofthe ear andthe auditory nervous system, and it discusses the cause and treatment of hearing disorders Most books on hearing focus either on the anatomy ... comprehensive coverage of disorders ofthe auditory system emphasizing the interaction between pathologies ofthe middle ear andthe cochlea andthe function ofthe nervous systemand vice versa Hyperactive ... original work on the different subjects Understanding ofthe anatomy andthe function ofthe auditory system together with knowledge about the pathophysiology ofthe auditory system are essential...
... at the entrance ofthe ear canal compared with the sound pressure that is measured in the place ofthe head The effect ofthe head on the sound at the entrance ofthe ear canal is related to the ... ratio between the effective area ofthe tympanic membrane andthe area ofthe stapes footplate, but the lever ratio ofthe middle ear bones also contributes The ratio of areas ofthe BOX 2.2 SOUND ... remarkable in the light ofthe FIGURE 2.12 (A) Average displacements ofthe umbo, the head ofthe stapes andthe lenticular process ofthe incus (B) The lever ratio at 124 dB SPL at the tympanic...
... anatomy andphysiologyofthe auditory nervous systemof clinical importance Most studies ofthe function ofthe auditory system have aimed at the coding of different kinds of sounds in the auditory ... in the ventral parts ofthe MGB ofthe thalamus, the nonclassical sensory pathways use the dorsal and medial division ofthe MGB as relay (Fig 5.10) [122] These divisions ofthe MGB receive their ... ofthe fourth ventricle (Fig 5.15B) [72] The other part ofthe olivocochlear system projects mainly to the contralateral cochlea andthe fibers of that system travel deeper in the brainstem The...
... The caudal portion ofthe floor ofthe lateral recess is the (dorsal) surface ofthe dorsal cochlear nucleus andthe rostral portion ofthe floor ofthe lateral recess is the dorsal surface of ... difference between the latency ofthe N1 ofthe AP and that ofthe response from the intracranial portion ofthe auditory nerve is the travel time in the auditory nerve from the ear to the recording ... the latency ofthe first peak in the dipole andthe length is the relative strength ofthe dipoles Note the short distance between the two first dipoles (peak I and II ofthe ABR) andthe third...
... stapedius musclecontraction decreases the input to the cochlea and thereby decreases thecontractionofthe stapedius muscle, and that in turn causes the input to the cochlea to again increase, and ... components of broad band sounds will elicit contractions ofthe stapedius muscle when the intensities of these components are above the threshold ofthe reflex and that will cause attenuation of low ... from the stapedius muscle [19] and in the flying bat where recordings of EMG potentials from the laryngeal muscles andthe middle ear muscles have shown that contractions ofthe middle ear muscles...
... increase the sensitivity and frequency selectivity ofthe ear (cf Chapter 3) The widening ofthe tuning ofthe basilar membrane broadens the “slices” ofthe spectrum of broad band sounds from which the ... this view of flexibility ofthe function ofthe auditory system That injury and loss of cochlear hair cells can cause profound changes in the structure and function ofthe central auditory system ... coherence ofthe nerve activity that reaches the cochlear nucleus The growth ofthe amplitude ofthe reflex response is reduced in 242 Section III Disorders ofthe Auditory Systemand Their Pathophysiology...
... tinnitus and abnormal perception of sounds such as hyperacusis and phonophobia) are some ofthe most diverse and complex disorders ofthe auditory systemand their causes are often obscure Often ... corresponding to the F1 frequency andthe other corresponding to the frequency of F2 The rate ofthe impulses is that of F0 for voiced sounds, and a quasi-random rate (average of 100 pps) for ... determined on the basis ofthe output of 16 band-pass filters The output ofthe six band-pass filters with the largest amplitudes is coded in the impulses that are applied to the electrodes in the cochlea...
... in the LPS group At the same time, 3-MH was also reduced, but the concentration of tyrosine and other mRNA and protein levels ofthe Ub system changed only slightly When the infusion dose of ... WL and JZ did the statistical analysis QC and WY wrote the first draft ofthe paper and JL commented on the draft All other authors provided comments and approved the final manuscript Page of ... longus muscleThe proteolytic rate ofskeletalmuscle was measured as net release of tyrosine for total protein and 3-MH for myofibrillar protein Compared to the control group, the rate of total...
... cascade system prevalent in the liver andthemuscle through steady state analysis The quantification incorporates the influences of all the effectors that regulate the output response ofthe glycogen ... the glycogen cascade systemofskeletalmuscleand liver In the present work, the cAMP concentration is considered to be the primary input to the glycogen cascade The fractional activations of ... information on the set of equations and list of parameters used for the simulation are given in the Appendix Most ofthe parameters and enzyme concentrations are taken from literature sources andthe same...