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optimal timing of allogeneic hematopoietic stem cell transplantation in patients with myelodysplastic syndrome

báo cáo hóa học:

báo cáo hóa học: " Function, Adjustment, Quality of Life and Symptoms (FAQS) in Allogeneic Hematopoietic Stem Cell " potx

Hóa học - Dầu khí

... MR, Childs R, Barrett AJ: Health-related quality of life in patients receiving reduced-intensity conditioning allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant 2006, 38(2):101-109.13. ... research,including Spanish speakers, and individuals undergoingreduced intensity transplantation or receiving treat-ment for disease relapse following transplantation. Theknowledge gained from ... DN, Atlam N, Fowler DH,Pavletic SZ: Determinants of functional performance in long-termsurvivors of allogeneic hematopoietic stem cell transplantation with chronic graft-versus-host disease (cGVHD)....
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Báo cáo y học:

Báo cáo y học: "Hematopoietic stem cell transplantation for systemic lupus erythematosus" ppsx

Báo cáo khoa học

... neutropenic interval by4–6 days compared with the same dose of cyclophos-phamide without hematopoietic stem cell support, andalso to hasten stem cell regeneration of the immunesystem under ... dialysis is initiated. Pharma-cokinetics of drugs such as high cyclophosphamidemetabolites are poorly understood in patients with renalfailure. For this reason, in patients with either renal insuffi-ciency ... direct comparison of HSCT with cyclophosphamide andATG versus the Hopkins’ treatment protocol incorporatinghigh-dose cyclophosphamide without stem cell support.Competing interestsNone declared.References1....
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Báo cáo hóa học:

Báo cáo hóa học: "Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-a 2b treatment" pptx

Hóa học - Dầu khí

... Comparison of regulatory T cell levels at baseline in patients with melanoma and healthy subjects.(A) Box plot showingbaseline regulatory T cell (Treg) levels in 22 patients with melanoma prior to interferon-a ... CD8+cellsasaninternalcontrol.OnlyCD4+cells expressing CD25 with higher intensities thanthe CD8+cells were included in the gate for CD25high cell s. The gate for CD25low cell s was set to include cellsexpressing ... and was receiving a secondline of chemotherapy with fotemustine following thereappearance of liver and lung metastases. Of the 17 patients t reated with adjuvant IFN-a 2b, 4 patients had very...
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Báo cáo hóa học:

Báo cáo hóa học: " Vaccination with a plasmid DNA encoding HER-2/ neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial" pptx

Hóa học - Dầu khí

... Effect of dose on immune response in patients vaccinated with an her-2/neu intracellular domain protein–basedvaccine. J Clin Oncol 2004, 22:1916-1925.44. Reilly RT, Machiels JP, Emens LA, Ercolini ... Vaccina tion with a plasmid DNAencoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial. Journal of Translational Medicine ... s.e.m.) binding activity of patients evaluable at all time points (patient #3,4, 8, pre, post and late). C. Binding activity in the serum of all patients at all available individual time points...
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Báo cáo sinh học:

Báo cáo sinh học: "CGB and GNRH1 expression analysis as a method of tumor cells metastatic spread detection in patients with gynecological malignances" potx

Điện - Điện tử

... identify-ing four and two individuals, respectively as cancer patients havin g tumor cell circulating in the blood flow.High CGB activity was found in blood of three patients with ovarian carcinoma ... indicatedthepresenceoftumorcellscirculatinginbloodof patients. The raw results of GNRH1 expression in blood of can-cer patients was fitted to three normal distributions.Two of these distributions corresponding ... distinguishing patients with tumor cells circulating in their blood andindicate the metastatic spread of these cells.AcknowledgementsThis study was supported by the Polish Ministry of Science...
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báo cáo hóa học:

báo cáo hóa học:" Health-related quality of life and self-related health in patients with type 2 diabetes: Effects of group-based rehabilitation versus individual counselling" pot

Hóa học - Dầu khí

... in four one-hour sessions of indi-vidual counselling with a diabetes nurse specialist, whohad a bachelor’s degree in education and was trained in motivational interviewing [19]. Using the patients ... recommendedlevel of 30 minutes of daily exercise. Over the sametime period, patients participated in three individualcounselling sessions with a dietician who was alsotrained in motivational interviewing ... differences in the SF-36 vitalityscale in patients with chronic conditions [29]. Patients suffering from a condition with a 5-point lower vital-ity score (compared with patients without that...
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Báo cáo hóa học:

Báo cáo hóa học: " Clinical significance of elevated B-type natriuretic peptide in patients with acute lung injury with or without right ventricular dilatation: an observational cohort study" potx

Hóa học - Dầu khí

... number of patients with percentages in parentheses*SPAP available in 39 subjectsFigure 1 Boxplot summary of BNP in patients with andwithout right ventricular (RV) dilatation. Median levels of ... different findingsmay be explained by the timing of measurementsobtained. Pulmonary hypertension with subsequent RVdilatation and dysfunction in mechanically ventilated patients with ALI is ... levels in ICU patients do not change signifi-cantly [11,41]. In summary, in patients with acute lung injury theplasma levels of BNP are increased, yet the reasons forthis increase remain unclear....
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Báo cáo khoa học:

Báo cáo khoa học: "Transarterial chemoembolisation (TACE) using irinotecan-loaded beads for the treatment of unresectable metastases to the liver in patients with colorectal cancer: an interim report" pdf

Báo cáo khoa học

... 2).Twenty-eight patients had previously been treated with hepatic surgery, 54 with prior systemic chemotherapy,including FOLFOX in 35 patients, FOLFIRI in 15, Avastin in 37 patients, and other biologics in ... Survival of patients treated with Irinotecan drug eluting beads with liver dominant hepatic metastasis after fail-ing standard chemotherapy b) Overall Survival of patients treated with Irinotecan ... eluting beads with liver dominant hepatic metastasis after failing standard chemotherapyFigure 1a) Disease Free Survival of patients treated with Irinotecan drug eluting beads with liver dominant...
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Báo cáo y học:

Báo cáo y học: "Altered dendritic cell distribution in patients with common variable immunodeficiency" pot

Báo cáo khoa học

... along with JFV, in charge of most of the CVID patients gathered in this study and contributed tothe writing of the article. MA and FL were in charge of CVID patients and contributed to the writing ... deVries JE: Peripheral blood lymphocytes of patients with com-mon variable immunodeficiency (CVI) produce reduced levels of interleukin-4, interleukin-2 and interferon-gamma, but pro-liferate normally ... role of IL-12 in dendritic cell- induced differentiation of naive B lymphocytes. J Immunol1998, 161:2223-2231.12. MacLennan I, Vinuesa C: Dendritic cells, BAFF, and APRIL:innate players in adaptive...
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Báo cáo y học:

Báo cáo y học: "The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus" potx

Báo cáo khoa học

... CD8+CD28- T cells [38-40]. An increase of these cells in patients with SLE might thusconstitute an effort of counter-regulation within the disturbedimmune system of SLE patients. Surprisingly, ... pre-dominant IFNγ secretion.To gain more insight into the role of autoantigen specific Tcells in SLE, we investigated spontaneous T cell responses tohnRNP-A2 in patients with SLE and in healthy ... response,emphasizing the role of T cells in SLE [18,19]. The cellularaspect of the immune response to DNA in its various forms hasbeen extensively studied, including the characterization of Tcells inducing...
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Báo cáo y học:

Báo cáo y học: " Predictors of infusion reactions during infliximab treatment in patients with arthritis" docx

Báo cáo khoa học

... tobe effective in treating a variety of inflammatory diseases. In combination with methotrexate, infliximab provides significantand sustained improvement in a majority of patients with rheu-matoid ... which includes an overview of the studiesinvestigating autoantibody profile during treatment with inflixi-mab, ANAs were detected in between 4% and 17% of SpA patients before initiation of treatment. ... and13% of patients with SpA developed infusion reactions (P =0.126). The OR for development of infusion reactions in RA patients with baseline ANA positivity alone was 2.1. Infliximabwithout...
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Báo cáo y học:

Báo cáo y học: "Presence of antibodies against cyclic citrullinated peptides in patients with ''''rhupus'''': a cross-sectional study" pdf

Báo cáo khoa học

... preferentially binds peptides containing thenon-standard amino acid citrulline (deiminated arginine) [11]. In addition, an abnormally increased function of the enzymepeptidylarginine deiminase 4 (PAD4; ... anti-CCPantibodies) to those in patients with RA. In addition, patients with rhupus display a clinical and serological profile indistin-guishable from patients with SLE. Moreover, the presence of other coexistent ... similar in allgroups of patients (two patients with rhupus, three patients with RA, and three patients with SLE also had SS).We found high titers of anti-CCP antibodies in four of seven(57%) patients...
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Báo cáo y học:

Báo cáo y học: "Markers of B-lymphocyte activation are elevated in patients with early rheumatoid arthritis and correlated with disease activity in the ESPOIR cohort" pdf

Báo cáo khoa học

... of alloreactive Bcells in patients with early RA. Markers of B -cell activation,such as beta2-microglobulin, immunoglobulin levels, free lightchains (FLCs) of immunoglobulins, and BAFF (B -cell ... associated with early RA.Conclusions Markers of B -cell activation are elevated in patients with early RA, compared with undifferentiated arthritis,independently of any systemic increase in BAFF ... higher in early RA than in UA. Some features of B -cell activation were nonethelessobserved in patients with UA, including BAFF levels that werehigher than in healthy donors, elevated IgG in 55% of...
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