new lord of the rings game middleearth shadow of mordor
The Female Brain is one of the most-talked-about books of the year. ppt
... irth of the F emale B rain glanced at their mothers’ faces. They frequently touched the forbid-den toy cow, even though their mothers shouted, “No!” The one-year-old boys, driven by their ... to get to the clothes hanging in their closets. One girl had a pink two-piece outfit, and the other had a green two-piece outfit. Their mother giggled every time she’d see them switch the tops—pink ... imagine, then, the negative impact on a little girl’s developing sense of self of the unresponsive, flat face of a depressed mother—or even one that’s had too many Botox injections. The lack of facial...
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Báo cáo khoa học: Interaction of the E2 and E3 components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus ppt
... representing the PSBD of the dihydrosuccinyltransferase chain of the 2-oxoglutarate dehydrogenase complex of E. coli [12]and of the dihydroacetyltransferase chain of the PDHcomplex of B. stearothermophilus ... 119–171) of the B. stearothermophilusE2p polypeptide chain with the dimer of a proteindomain (E3int) representing the interface domain (resi-dues 343–470) of B. stearothermophilus E3. The use of the ... close to the twofold axis of E3preventing the association of a second PSBD [28,29]. The interaction occurs at the C2-axis of symmetry in the E3 dimer, chiefly with the interface domain of E3,which...
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How group work is used in speaking lesson of the first year major students of english at viet nam university of commerce
... the former, 83.3% of the teacher often grouped students of the same sex while only 20% of the students chose it and for the latter, group students of different sexes was the choice of 80% of ... understanding of using group work in the speaking lesson at VUC.1.2. Aims of the study The purpose of this study is to explore the reality of the use of group work in the speaking lesson of 1st- ... near each other” accounted for 100% of the teachers and 90% of the students. However, almost all of the teachers and students had different view on the way of grouping students of the same or...
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Tài liệu THE HISTORY OF THE RISE, PROGRESS, AND ACCOMPLISHMENT OF THE ABOLITION OF THE SLAVE-TRADE pdf
... was the readiest way of converting them to the principles of the Christian religion. These, then, were the first forerunners in the great cause of the abolition of the Slave Trade: nor have their ... held the reigns of the government of Spain till Charles the Fifth came to the throne, for the establishment of a regular system of commerce in the persons of the native Africans. The object of ... nature of it; and of the extent of it; and of the difficulty of subduing it.—Usefulness also of the contemplation of this subject. I scarcely know of any subject, the contemplation of which...
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Tài liệu Đề tài " Asymptotic faithfulness of the quantum SU(n) representations of the mapping class groups " pdf
... from the rest of the mapping tori as a purelyTQFT consequence of Corollary 1.In this paper we have initiated the program of using of the theory of Toeplitz operators on the moduli spaces in the ... multiple of the identity. Wewill suppress the superscript on the quantum representations and simply writeρk= ρn,dkthroughout the rest of the paper.Our key idea in the proof of Theorem 1 is the ... (see the proof of Theorem 7). Theorem 1 now follows directlyfrom knowing which elements of the mapping class group act trivially on the moduli space M. The assumptions on the pair (n, d) in Theorem...
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Báo cáo khoa học: Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein pptx
... responsible, from a thermodynamic point of view, for the binding of the monomeric species of CAC?We have previously discussed the variation in the freeenergy of binding as a function of the changes ... relationshipbetween S2and the location of structural elements(Fig. 4). Furthermore, the Rexterms are distributedthroughout the 3D structure of the protein, and most of them are large (Fig. 4); the exception ... (i.e. the spectral density function at the Larmor frequency of the 15N) and J(0.87xH) (i.e. the spectral density function at the 0.87 times the Lar-mor frequency of the 1H) are independent of...
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Báo cáo khoa học: Solution structure of the active-centre mutant I14A of the histidinecontaining phosphocarrier protein from Staphylococcus carnosus ppt
... wascomputed as the ratio of the s tandard deviations of the chemical shifts of the amide nitrogen and p roton nuclei.ResultsDetermination of the three-dimensional structure of HPr(I14A)To allow the comparison ... system of His15 and a distortion of the N-terminus of the first helix, which supports the histidinering. In ad dition, the C -terminal helix is bent because the sidechain of Leu86 located at the ... parallel to the a-helices and the b-sheet of the protein. As the 1HN-15Nbond vectors in the a-helices are therefore almost parallel to the z-axis, their size is mainly determined by the positiveeigenvalue...
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Adventurers of the Far North A Chronicle of the Frozen Seas doc
... with one another the weapons of their common stock. The advance was made in the middle of the night, but at this season of the year the whole {60} scene was brilliant with the light of the midnight ... land offered nothing to their search, the air was moderate and the weather singularly mild. The broad sheet of open water, of the very colour of the ocean itself, buoyed up their hopes of the ... opportunity of alleviating the extremehunger that I suffered with the refuse of the table of one of my acquaintances.At the end of the month (December 1770), they reached the woods, a thick growth of...
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Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot
... is the b-site APP-cleaving enzyme 1 (BACE1). Here, we investigated the effects of genetic manipulation of BACE1 on the processing of the APP family of proteins. BACE1 expression regulated the ... charac-terize the impact of BACE1 inhibition as a putativetherapy for the treatment of AD. We found that the de novo production and the endogenous levels of ICDswere not reduced by deletion of BACE1. ... inhibition of BACE1 will not adversely affect the potentially important signaling role of the ICDsreleased by the APP family of proteins, but mayimpact on other functions of this family of proteins.Experimental...
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Báo cáo khoa học: Structure–function analysis of the filamentous actin binding domain of the neuronal scaffolding protein spinophilin pot
... (Fig. 2A,B). The NMRspectra of these constructs perfectly resembled the spectra of unfolded proteins: they showed no signs of either amide proton dispersion, which is indicative of hydrogen bonding ... description of the molecular components involved in the regulation andmaintenance of dendritic spine morphology is funda-mental to our understanding of the functions of the central nervous system. The ... [38]. In the presence of theseABD constructs, the concentrations of fluorescentactin polymers appeared to be higher because of the precipitation of crosslinked actin polymer networksonto the glass...
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Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot
... to the CBM that playspecific roles in activation of the receptor by these twocytokines. The ligand independent activation of the D5-GCSFRchimera occurs in both the absence and the presence of LIFR ... a copre-cipitation of gp130 with LIFR independently of the lysisbuffer used for the disintegration of the cells (data notshown). Because of the high expression levels of the transiently transfected ... membrane-proximaldomains of gp130 is limited to ensure the correct spacingbetween the CBM and the membrane, each of the domainswas replaced by the corresponding domain of the GCSFR. The replacement...
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rock v pop music of the 1970 s v music of the 1990 s
... came the dawn of new instruments such asdrums, pianos, flutes, and guitars (Romeu 1). Both eras of rock usedthese types of musical instruments in one way or the other. They are the essentials of ... the developing culture of the seventies. Bands often used their popularity to spread their feelingson such topics. They were, and still are, the central of communicationbetween all genres of ... andpromiscuous sex. There was more to rock music than this, much more.In the musician's lyrics, from the classic rock music era of the seventiesto the more modern forms of rock music of the nineties,...
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Báo cáo khoa học: Antimicrobial and conformational studies of the active and inactive analogues of the protegrin-1 peptide docx
... activity of the peptides. A better under-standing of the mode of action of these peptides iscrucial for the development of a new generation of antibiotics.It is known that, in the absence of both ... reduce the cost of synthesis (arginine isvery expensive). The second analogue, BM-2, was designed in such away that the relative importance of the rigidity andcharge at the turn of the b-hairpin ... at the two spatial tips of the molecule, at the N-terminus with Arg1 and in the turn in the presence of Arg7 and Arg9 (see Figs 3 and 4). The shorter analogue, BM-2, was the most flexible of all...
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