new insights into the hypothalamic control of fsh and lh by cytokines and nitric oxide
báo cáo khoa học: " Construction of a potato consensus map and QTL meta-analysis offer new insights into the genetic architecture of late blight resistance and plant maturity traits" pps
... is the number of hypothetic meta-QTLs of a model) “Delta” is the rescaled value of the criterion, it is the difference between the value of the given model and the value of the best model The ... onto the consensus map It is based on a scaling rule between the positions of the flanking markers of the QTLs on their original maps and the positions of these markers on the consensus map The ... one hand, and within maturity traits (Maturity, Vigour), on the other hand QTL names are written to the left of the bars QTL nomenclature is as follows: the name of the first author of the original...
- 17
- 593
- 0
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... one of the manganese ions This, together with the fact that the positions of other Fig Scheme of the binuclear manganese cluster and the localization of the side-chains of Asp153 and Asn153 in the ... with the sequences of 1CEV and 1RLA and pasted into the structural alignment The alignment was then corrected by hand Since the sequences of the two arginases and agmatinase greately differ in the ... concerned a loop located at the entrance of the active site cleft, and defined by residues 124–141 in the sequence of the bacterial arginase Whereas the backbone and some of the side chains are very...
- 5
- 475
- 0
Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx
... (dobserved–drandom coil) in ppm for HtA at pH 4.1 and 298 K The amino acid sequence and the elements of secondary structure are shown; b-strands are represented by arrows and the a-helix by a spiral ... further than other ribotoxins to become smaller and more economical At the same time, the active site of HtA, as revealed by the 3D structure, shows a different arrangement to that shown by the ... basis of HtA function The reaction catalyzed by ribotoxins follows a mechanism of transphosphorylation, which implies the A Fig Stereo diagram of the active center of HtA (A) Superposition of the...
- 10
- 607
- 0
Báo cáo khoa học: New insights into the functions and N-glycan structures of factor X activator from Russell’s viper venom pot
... loss of the substituents on the 6-arm and the bisecting GlcNAc The identification of Lex and SLex by MS/MS sequencing was further corroborated by western blot analyses (Fig 8) using a panel of specific ... peptide of 23 residues, and the predicted sequence for its mature protein matches that published previously [8] The amino acid sequences of LC1 and LC2, together with those of other homologues of ... HC, the light chains appear to confer the substrate specificities of RVV-X [12] Collectively, the primary sequences of the three subunits of RVV-X (Figs and 5) suggest the possible presence of...
- 15
- 562
- 0
Báo cáo khoa học: New insights into the P-glycoprotein-mediated effluxes of rhodamines doc
... also the measurement of the rate of passive diffusion of the dye through the plasma membrane This cannot be done by the simple measurement of the increase of the fluorescence signal (Fcyto) of the ... proportional to the amount of rhodamine free in the cytosol This observation allows the further determination of the concentration of drug free in the cytosol of resistant cells The determination of ka ... Na+-buffer on the one hand and K+ buffer on the other hand In Na+-buffer a strong decrease of the fluorescence signal was observed due to the accumulation of the lipophilic cation mainly in the mitochondrial...
- 10
- 386
- 0
Click Here: The State of Online Advertising - New insights into the beliefs of consumers and professional marketers ppt
... popular form of online advertising Advertising/Marketing professionals considered in the bottom professions among consumers – along with actors and dancers; not highly regarded by marketing professionals ... Visit the product's website 11% Visit the product's social media page Other 6% Like' the product 5% 'Comment' on the product 4% Hide that person from your social media newsfeed 2% Recommend the ... magazines and while watching a favorite TV show are the two most preferred places to look at an ad Majority of respondents use social media; over half have liked on behalf of their favorite brands,...
- 16
- 505
- 0
Báo cáo sinh học: "Making the jump: new insights into the mechanism of trans-translation" pdf
... RNA at the start of translation How then is the resume triplet properly positioned? And what mechanism allows the ribosome to take off from the damaged mRNA template and land precisely on the tmRNA’s ... structures of (a) tRNA, (b) mRNA and (c) tmRNA (a,c) The 3’ and 5’ termini, the amino acid acceptor stem (AC) and the anticodon (A), D and T arms are indicated (b,c) The Shine-Dalgarno sequence (SD), the ... permutations of the -1 triplet and determined their effect on survival in the kanamycin resistance assay They found that eight of the 18 codons that were prohibited according to the -1 hypothesis [12]...
- 4
- 279
- 0
Báo cáo y học: "New insights into the pathogenesis of glucocorticoid-induced avascular necrosis: microarray analysis of gene expression in a rat model" potx
... humidity of 48% Food and water were provided ad libitum with a standard rodent diet The weight of the rats was followed Page of 12 before and after the implant of a prednisone pellet for the first ... Suppression of osteoblast and osteoclast precursor production, increased apoptosis of osteoblasts and osteocytes, prolongation of the lifespan of osteoclasts and apoptosis of endothelial cells ... lateral side of the neck by surgically making an incision and developing a pocket about cm beyond the incision site The pellet was placed in the pocket and the incision was sutured Based on the manufacturer's...
- 12
- 312
- 0
Báo cáo khoa học: New insights into structure–function relationships of oxalyl CoA decarboxylase fromEscherichia coli pptx
... nitrogens of residues I322 and I303 interact with nitrogen atoms of the adenine ring and the c-carboxyl group of the side chain of residue D302, the d and x nitrogen atoms of the guanodino group of ... N404 The oxygen of the a phosphate of ribose diphosphate is stabilized by interactions with the x nitrogen of the guanidino group of residue R403 and the c carbonyl oxygen of residue N404 The ... was found for the S-acetyl pantetheine part of acetyl CoA, and consequently the model for the inhibitor remains incomplete The nitrogen atom of the amino group of the adenosine ring of PADP interacts...
- 13
- 435
- 0
Báo cáo khoa học: Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis pptx
... groups with the main chain nitrogen and main and side-chain oxygen atoms of Ala59 and Glu61 of one subunit and with the main chain nitrogen of Asn114Â of the other subunit The contacts of the ribityl ... series of inhibitors that mimic the substrate, the intermediates and the product of the reaction [1622] catalysed by LS The rst detailed description of the active site of LS was provided by the ... concentrations of ligand, and Q is the fraction of sites occupied by ligand X The initial estimates for n, Ka and DH were rened by standard Marquardt nonlinear regression methods The binding entropy DS and...
- 15
- 439
- 0
báo cáo hóa học:" More insights into the immunosuppressive potential of tumor exosomes" pptx
... adds then a further pathway to the potential modulating properties of these peculiar organelles If tumor exosomes are such a powerful instrument of environmental shaping, then getting rid of them ... proteins, like in case of viruses and cancer microvesicles [1] The approach could be further implemented by the attachment of clinical grade molecules and antibodies to the cartridge resin, to ... promoting autocrine secretion of MMP and VEGF [29] The evidence that these organelles can also shape protein synthesis through the transfer of functional mRNAs and microRNAs, as recently reported...
- 4
- 426
- 0
Báo cáo hóa học: " New Insights into the RLS Algorithm" pdf
... window, the level of noise at the system output, and the condition number The closer the exponential window is to one, the better the misalignment is, but the tracking abilities of the RLS algorithm ... 5, 6, and show the evolution in time of the input signal, the normalized misalignment (we approximate the normalized misalignment with its instantaneous value), and the condition number of the ... misalignment will degrade by increasing the condition number of the input signal For example, by increasing the condition number from to 10, the misalignment will degrade by 10 dB; the simulations confirm...
- 9
- 371
- 0
Báo cáo y học: " Draft genome sequence of the Daphnia pathogen Octosporea bayeri: insights into the gene content of a large microsporidian genome and a model for host-parasite interactions" pps
... rather than the size of the genome in which they are found Evidence for the progressive loss of ancestral genes throughout the evolution of the microsporidian lineage Prior to this study, the ... ng of sheared DNA The downside of very short reads (35 bp) was mostly offset by the deep sequence coverage, allowing a detailed analysis of the coding capacity of the O bayeri genome, but not of ... metabolites from the host At the extreme, only one-quarter of the ATP transporters present in other microsporidia and around half of the Enc cuniculi homologs of amino acid and sugar transporters...
- 12
- 400
- 0
Mechanical insights into the physiological functions of claudin mediated adhesion at tight junctions a
... positions of the energy barriers can be determined from xβ To compare the topography of the energy landscape of the dissociation of Cldn1/Cldn1 and E-cadherin/E-cadherin, the geometric locations of their ... contact force of 200 pN and contact time of ms were used,
- 6
- 198
- 0
Mechanical insights into the physiological functions of claudin mediated adhesion at tight junctions b
... contact force of 200 pN and contact time of ms were used, b25% of the force–distance curves showed bond rupture events On the basis of Poisson statistics,25 the low frequency of these de-adhesion ... the same reactive coordinates to compare the topography of the energy landscapes of the dissociation of Cldn2/ Cldn2 and C2E1/C2E1 complexes (Fig 8) However, it is possible that Cldn2/Cldn2 and ... of bounded complex The geometry of the conceptual energy landscape for the dissociation pathway can be constructed based on these kinetic parameters The geometric locations of their bound states...
- 11
- 186
- 0
Mechanical insights into the physiological functions of claudin mediated adhesion at tight junctions c
... (0.1–2 μm/s) and were analyzed for the magnitude of the rupture events and the apparent loading rate (defined as the slope of the retrace curve prior to the rupture event multiplied by the reproach ... landscape for the dissociation pathway To compare the topography of the energy landscapes of the dissociation of Cldn2/Cldn2 complexes at different pH conditions, the geometric locations of their ... generating the histograms (b) The slope of the curve just before rupture multiplied by the reproach velocity (Vr , expressed in nm/s) defines the loading rate (rf, expressed in pN/s) The height of the...
- 9
- 307
- 0
New insights into crystallization from thermodynamics to polymorphism and kinetic
... of the mass of the standard or the test solution is due to the volatile solvent, either by evaporation or by condensation By mass balance, the concentrations of the equilibrated reference standard ... concentration of the test solution If the solvent is the only volatile component, analyzing the concentrations of both the reference standard and the test solution can be done simply by weighing the reference ... instruments, the known concentration of the standard at equilibrium yields the solvent activity of the reference 13 standard hence the solvent activity of the test solution, corresponding to the determined...
- 214
- 267
- 0
Party Age and Party Color New Results on the Political Economy of Redistribution and Inequality
... those of the poor or the rich Consistent with this, they show that when the ratio of the incomes shares of the top to the middle income deciles is higher and the ratio of the middle to the lowest ... impulse: the older is the left-wing party, the smaller is the sharegain of the poor and the larger (although still negative) is the sharegain of the rich The effects are large: a one standard deviation ... were with the Development Research Group of the World Bank and was supported by the Research Support Budget of the World Bank We are extremely grateful for the comments of John Huber and of participants...
- 29
- 209
- 0
Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf
... inhibition of the binding of the superoxide substrate and the other to product inhibition by hydrogen peroxide There are two mechanisms proposed for the reaction cycle of Mn ⁄ Fe-SOD: the 5-6-5 ... Mn-reconstituted enzyme and an additional water oxygen, which, together with the OD2 of Asp165, the NE2 of His79 and the NE2 of His169, formed an equatorial plane (Fig 3B) The metal ion and the addi˚ tional ... of the reduction step from superoxide to hydrogen peroxide [26] These findings lead to the hypothesis that Fe-bound ApeSOD mimics the product-inhibited form and the shift of Tyr39 suppresses the...
- 12
- 762
- 0
Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx
... allosteric control, and that this allosteric control arises from the homotropic effects of one of the substrates, i.e pantoate [8,9] One of the interesting features of the plant PSs is the presence of ... as of the alleviation of this inhibition by another substrate of the enzyme, ATP, are presented [8,9] Results Solution properties of the N-terminal domain of PS, the C-terminal domain of PS, and ... the A-chain and B-chain of nPS, and in the case of His37, the v1 torsion angle changes from 63.34° to )67.80° and )52.11° for the A-chain and B-chain of nPS, respectively The imidazole ring of...
- 16
- 791
- 0
Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25