mucoadhesion permeation enhancement and enzyme inhibition properties for the delivery of hydrophilic macromolecular drugs
Tài liệu APICE: Common Mediterranean strategy and local practical Actions for the mitigation of Port, Industries and Cities Emissions pdf
... prominent forums for discussing the latest scientific developments, applications and implications for policy and other users An important feature of the conference is that it brings together scientists ... a firm reference for any future study and/ or development Number, emission profile (i.e the chemical composition of the pollutants emitted by a specific source) and impact of the major pollution ... evaluation of the air quality pollution in the port cities involved in APICE (Barcelona, Marseille, Genoa, Venice and Thessaloniki) It this framework, the air quality status of the five port...
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Investigation of au and in as solvents for the growth of silicon nanowires on si(1 1 1)
... following the effects of different diffusion coefficients of gold and indium on silicon, the solubility of substrate atoms in the two metals, the surface tension of gold and indium and the surface ... diagrams; top: In–Si and bottom: Au–Si Since the state of the substrate surface after desorption and the vacuum conditions are the same during evaporation of gold and indium, the different liquid–solid–vapor ... healed during the growth process A recovery of the crystalline structure around the pores is therefore possible even at the relatively low temperatures used for the wire growth Conclusions The different...
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Financial Accounting: A comprehensive and practical online guide for the basics of financial accounting docx
... visit: www.kesdee.com of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of of 28 14 08 07 15 07 63 ... Library Library Library Library Library Library Library Library Library Library of of of of of of of of of of of of of of 03 02 03 02 03 02 03 04 02 03 07 10 04 03 Courses Courses Courses Courses ... Financial Institutions Others The themes of this product are: Understand the Accounting Framework Understand the Accounting Process Understand the process of Finalization Understand the Financial Statement...
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Báo cáo hoa học: " Research Article Necessary and Sufficient Conditions for the Existence of Positive Solution for Singular Boundary Value Problems on Time Scales" pot
... that there is a large number of functions that satisfy the conditions of Theorem 3.3 In addition, the conditions of Theorem 3.3 are also easy to check Acknowledgments This work is sponsored by the ... be the number if it exists with the property that given ε > there is a neighborhood U of t with y ρ t −y s − y∇ t ρ t − s
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Báo cáo hóa học: " Combination of Polymer Technology and Carbon Nanotube Array for the Development of an Effective Drug Delivery System at Cellular Leve" pptx
... data and model fitting (n = 3) where C2 is the protein in the bulk, C10 is the concentration inside the gel, S and V1 are, respectively, the surface and the volume of film, V2 is the volume of the ... up to 90% and, in the third day, about 96% of the cells have well-developed neurites Figure 6b reports the trend of neurite length in the time: already after 24 h, the mean length of the neurite ... presence, these cells undergo a dramatic change in phenotype whereby they acquire most of the characteristic properties of sympathetic neurons Other salient responses to NGF include cessation of proliferation,...
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Báo cáo vật lý: "Immobilization of Dithizone onto Chitin Isolated from Prawn Seawater Shells (P. merguensis) and its Preliminary Study for the Adsorption of Cd(II) Ion" pdf
... mechanically shaken for h and the adsorbents were then separated from the adsorption medium The concentration of Cd(II) ions in the solution was determined by AAS and the amount of adsorbed metal ... is the amount of metal ions adsorbed onto unit amount of the adsorbents (mg/g), Co and CA are the initial and final concentrations of metal ions (µg/ml), respectively, V is the volume of the ... (ml), and m is the weight of the chitin or chitin-dithizone adsorbents The effect of adsorbent mass on the amount of adsorbed Cd(II) ion was investigated using the same procedure, but the weight of...
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báo cáo khoa học: "Surgical perspectives from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer" pps
... selection of patients for Page of 10 APBI [22,23], and these guidelines formed the basis for patient selection in the EBT multicenter study [20] Of the 65 patients that met the initial screening ... help the patient meet the eligibility criteria Careful attention to the depth of the lesion from the skin using ultrasound measurements is needed for optimal design of the lumpectomy and the post-lumpectomy ... skin, and an adequate skin bridge will maintain the distance from the balloon to the skin surface The greater the volume of the balloon, with the attendant compression of adjacent breast tissue, the...
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báo cáo khoa học: " Social networks, work and network-based resources for the management of long-term conditions: a framework and study protocol for developing self-care support" potx
... between the Greater Manchester NHS Trusts and the University of Manchester and is part of the National Institute for Health Research The authors are members of the Patient Theme of CLAHRC for Greater ... a sense of normality and well-being for themselves and for others (see Figure patient-focused outcomes) 2) Illness management and types of work The scope of the potential involvement of different ... translating research and implementation into practice [5], forms the basis of the Collaboration for Leadership in Applied Health Research and Care for Greater Manchester (CLAHRC) The focus of the research...
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Báo cáo y học: "Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report" pdf
... three months of treatment Between the commencement of the new psychotropic treatment regimen in October 2007 and the significant improvement of the depressive symptoms as described above, the arthritis ... long before and after the clinical improvement This leaves us to the discussion of the anti-inflammatory effects of antipsychotic medication on CRP levels and a patient’s clinical symptoms The literature ... consent was obtained from the patient for publication of this case report and any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal Abbreviations...
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Báo cáo y học: "Comparative study between the Hybrid Capture II test and PCR based assay for the detection of human papillomavirus DNA in oral submucous fibrosis and oral squamous cell carcinoma" pdf
... approximately 26% of all OSCC of the head and neck worldwide [7] but the most accurate and consistent study for OSMF and OSCC, in which viral integration and the expression of viral oncogenes (E6 and E7) ... pg/ml of sample Interpretation of Cut off value (RLU of specimen/mean RLU of PC) Cut-off ratio of to 0.99 is negative for HR HPV; Cutoff ratio greater than 1.0 positive for HR HPV The cut off ratio ... (HC-II) and approved by the US food and drug administration (FDA) The performance characteristics of HC-II assay and the PCR for detection of HPV DNA have been compared in cervical lesions and results...
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Báo cáo y học: " RNA silencing and HIV: A hypothesis for the etiology of the severe combined immunodeficiency induced by the virus" pot
... cleavage of the corresponding sense mRNAs at the many sites available in the exactly complementary regions spanning the U3R-3', and the beginning portion of the TAR mRNA at the 5'end of HIV sense ... most of the clades of group M (A-D, F-H, J and K), with the exception of the O group strains (underlined, additional file 2)[106,107] There is even conservation of a nucleotide "seed" of the HAAmiRNA1 ... 5'phosphate and nt 3' overhang at the base [34,87] PremiRNA is then transported out of the nucleus by Ran-GTP and Exportin-5 [88-90], where it would be cleaved by the RNase III enzyme Dicer to form the...
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Báo cáo y học: " Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors. Implications for the mechanism of traumatic myocardial infarction" pot
... u2, the particle size a, the quantities and shapes of inclusions, and the physical properties of the phases (see equation 1) (The effects of the shape and multiplicity of particles, and of some ... decrease the permeability of the endothelium [16] and decrease the rate of removal of lipids and lipoproteins, which in turn can lead to the formation of lipid stripes directed along the blood flow and ... determine the destruction, i.e the detachment and separation of particles from the surface The results of the experiment are given in Table The role of the non-Newtonian viscosity of blood has...
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Using biological networks and gene expression profiles for the analysis of diseases
... this case, the variances of the classes are pooled to compute the standard error, s2 and s2 denote the variance of the two classes respectively, N1 and N2 denote the sample size of the two classes ... Tk be the ordering of k genes sorted in increasing order of the modified t-statistic The permutation test randomly swaps the class labels of the original data, preserving the proportions of the ... depends on the correlation of the gene with the one of the two phenotypes We theref phenotype The enrichment score is the maximum deviation from Moreover, in the permutation test the FCS and GSEA...
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In vitro and in vivo evaluation of transferrin conjugated lipid shell and polymer core nanoparticles for targeted delivery of docetaxel
... 2.1.3 Limitations of traditional chemotherapy One of the problems of traditional chemotherapy is the dosage form and toxicity of the substances used As most of the anticancer drugs are highly ... recognize and remove the drug before they can perform their designed therapeutic function The common opsonins are immunoglobulins and C3, C4, and C5 of the complement system as well as other blood ... vincristine and vinblastine) and their semi-synthetic analogues (e.g vinorelbine) and the taxanes (e.g paclitaxel and docetaxol) They act on the microtubules, an essential part of the cytoskeleton of...
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Cluster analysis and ontology generation techniques for the development of scholarly semantic web
... we review the development and the state -of -the- art of technologies for the Semantic Web First, we discuss the traditional World Wide Web, which is the precursor of the Semantic Web, and markup ... of the research have been given We have also listed the contributions that have been achieved The rest of the thesis is organized as follows Chapter reviews the Semantic Web and the state -of -the- art ... for XML Information Retrieval (ELIXIR) [28] However, due to the lack of a standard for knowledge annotation, such systems are still unable to share their information With the advancement of the...
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Báo cáo hóa học: " Efficient data replication for the delivery of highquality video content over P2P VoD advertising networks" pdf
... best-effort delivery service in the form of UDP (the size of the UDP datagram is limited to 1,500 bytes), which does not guarantee reliability or the delivery order of network packets [33] Nevertheless, ... transform (2D-DWT) is then performed in each temporal subband to decompose the frames spatially The solid line shows the data paths of the texture data, and the dashed line indicates motion information ... by the quantity of the received video chunks in a set of resource-sharing peers We further assume that the maximum value of R-D slopes for any given packet is therefore an approximation for the...
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Báo cáo hóa học: " A systematic review of mobility instruments and their measurement properties for older acute medical patients" doc
... than the MCID for the EMS and the original version of the HABAM but not for the PPME These data were not available for the Rasch refined version of the HABAM Validity The PPME has face and content ... in the final stages of drafting of the manuscript and given approval for the version to be published JK contributed to the conception and design of the review, the analysis and interpretation of ... for the HABAM Although the feasibility of the EMS has not been investigated, the HABAM has fewer equipment requirements than the EMS and PPME and is therefore likely to be the more feasible of...
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Báo cáo y học: " Tumour necrosis factor-α stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-κB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b" doc
... transducer and activator of transcription Discussion The findings of the present study suggest involvement of AP1 and NF-κB, but not of p38 or ERK1/2, in the TNF-αenhanced formation of the immunostimulating ... International; Fisher Emergo, Landsmeer, The Netherlands) and preincubated for hours in the presence or absence of SN50 (100 µg/ml or 200 µg/ml) and thereafter stimulated for 30 with TNF-α (0.5 ng/ml) ... 105/well) were incubated in the presence and absence of TNF-α and in the presence of SN50 for hours, as described in Materials and methods Results are representative for one of the two independent experiments...
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Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"
... other RA therapies where the drugs are typically discontinued if they are not effective Because of similarities in both the descriptive characteristics of the study populations of biologic and ... sensitivity and specificity, unlike PPV and NPV, should be less dependent on the prevalence in the population, and more reflective of the test itself, lessening the impact of any unique features of the ... users and the performance characteristics of the effectiveness algorithm between biologic and DMARD treatment episodes, the data were shown throughout for the biologic users as a unique group, and...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... system, in the distal segment of the tubule Inhibition of glucose reabsorption in the kidney, mediated by the SGLT cotransport system, represents a promising therapeutic target for the control of hyperglycemia ... hydrolysis-resistant, synthetic S-analogs of natural O-glucosides involved in the biosynthesis of chrysomelidial and salicin These substances are synthesized and secreted as part of a defense mechanism ... larvae of beetles (Chrysomelidae) Their synthesis has been previously described [31-33] For the purpose of the present study the thioglycosides used were selected and grouped based on their differences...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25