management of severe traumatic brain injury in infants
Báo cáo khoa học: "SOFA is superior to MOD score for the determination of non-neurologic organ dysfunction in patients with severe traumatic brain injury: a cohort study" doc
... dysfunction in severe traumatic brain injury. Crit Care Med 2005, 33:654-660.3. Zygun DA, Doig CJ: Measuring organ dysfunction. In Yearbook of Intensive Care and Emergency Medicine Edited by: Vincent ... Lenzlinger PM: Analysis of immunemediator production following traumatic brain injury. In Shock,Sepsis, and Organ Failure -Brain Damage Secondary to Hemor-rhagic -Traumatic Shock, Sepsis, and Traumatic ... source of cerebral ischemia following severe brain injury in the Traumatic Coma Data Bank. Acta Neurochir Suppl(Wien) 1993, 59:121-125.17. Moreno R, Vincent JL, Matos R, Mendonca A, Cantraine...
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Báo cáo y học: " Differential temporal profile of lowered blood glucose levels (3.5 to 6.5 mmol/l versus 5 to 8 mmol/l) in patients with severe traumatic brain injury" docx
... limits is controversial in patients with severe traumatic brain injury, because decreasedblood glucose levels can induce and aggravate underlying brain injury. Methods In 228 propensity matched ... we investigated the impact of maintain-ing blood glucose levels within low and tight limits on fluctua-tions in blood glucose values, insulin and norepinephrinerequirements, alterations in intracranial ... in arterial blood glucose, insulin and norepinephrine dose, and ICP. Shown are changes in arterial blood glucose, insulin and norepine-phrine dose, and intracranial pressure (ICP) in surviving...
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Báo cáo y học: "Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial" pdf
... recently been shown in avariety of animal models, including ischemic and traumatic brain insult models [3-6]. Postinjury administration of proges-terone in experimental models of head injury confers ... by traumatic brain injury. Exp Neurol 2002, 178:59-67.14. Pettus EH, Wright DW, Stein DG, Hoffman SW: Progesteronetreatment inhibits the inflammatory agents that accompany traumatic brain injury. ... progesterone followingcontinuous intravenous infusion in patients with acute moder-ate to severe traumatic brain injury. J Clin Pharmacol 2005,45:640-648.30. Goss CW, Hoffman SW, Stein DG: Behavioral...
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Báo cáo y học: "In vitro norepinephrine significantly activates isolated platelets from healthy volunteers and critically ill patients following severe traumatic brain injury" pptx
... whether norepinephrine-stimulated plateletsmight induce additional brain damage warrant furtherinvestigations.Introduction In clinical routine, norepinephrine is used to increase andmaintain arterial ... of surface P-selectin in platelets isolated from severe traumatic brain injury patients compared with healthy controlsChanges in expression of surface P-selectin in platelets isolated from severe ... pressure; ICU = intensive care unit; IL = interleukin; PRP = platelet-rich plasma; SjvO2 = jugular venous oxygen saturation; sTBI = severe traumatic brain injury; TBI = traumatic brain injury; TRAP...
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Báo cáo y học: "Differential influence of arterial blood glucose on cerebral metabolism following severe traumatic brain injury" pptx
... irrespective of the type of lesion and the predominantside of the brain lesions (Table 1) (right-sided brain lesions: 13 of 15 patients; left-sided brain lesions: 7 of 8 patients; bilateral brain lesions: ... decreased brain tissue pH inversely correlated with ele-vated brain lactate and pCO2 during the first posttraumaticday [52]. Brain pH can either be determined directly by insert-ing specialised ... cortical spreading depression and peri-infarctdepolarisations in the acutely injured human brain. Clin Neu-rophysiol 2008, 119:1973-1984.12. Park E, Bell JD, Baker AJ: Traumatic brain injury: can...
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Báo cáo y học: "Optimizing cerebral glucose in severe traumatic brain injury: still some way to go" pdf
... optimizingcerebral glucose in acute brain injury has more recentlyattracted the interest of physicians involved in neurocriticalcare. The key research themes that are emerging includedetermining ... using arterial and jugular venous measure-ments to determine a range of plasma glucose betweenwhich cerebral metabolism is optimized in patients with traumatic brain injury (TBI). Their findings, ... the GLUT1 transporter in theblood -brain barrier after severe TBI decreases endothelial fluxCommentaryOptimizing cerebral glucose in severe traumatic brain injury: still some way to goCameron...
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Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"
... Refractory intracranial hypertension is a leading cause of poor neurological outcomes in pa-tients with severe traumatic brain injury. Decompressive craniectomy has been used in the management of refractory ... of severe traumatic brain injury. J Clin Neurosurg 2006;3:124-125. 43. Whitfield PC, Patel H, Hutchison PJ, et al. Bifrontal decom-pressive craniectomy in the management of posttraumatic in- tracranial ... subsequent management. At present, in the absence of prospective randomized controlled trials to prove the role of decompressive craniectomy in the treatment of traumatic brain injury, these...
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báo cáo hóa học: " Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice" pot
... time-point, and TBI group Fig.Kinetics of body weight changes for up to 7 days after trau-matic brain injury (TBI)Figure 5Kinetics of body weight changes for up to 7 days after traumatic brain injury ... PF: Elevated intracranial IL-18 in humansand mice after traumatic brain injury and evidence of neuro-protective effects of IL-18-binding protein after experimen-tal closed head injury. J Cereb ... (7d)**Posttraumatic injection of mAb 1379 attenuates C5a levels in serum of head-injured miceFigure 2Posttraumatic injection of mAb 1379 attenuates C5a levels in serum of head-injured mice....
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Traumatic brain injury and the effects of diazepam, diltiazem, and MK-801 on GABA-A receptor subunit expression in rat hippocampus ppt
... phos-phorylation of subunit proteins. Increases in glutamateafter injury trigger VGCC and NMDA receptors, increas-ing [Ca2+]i, and resulting in activation of CaMKII. A sin-gle dose of DZ can ... subunits in the brain typicallyform a limited number of receptor combinations [23].Reportedly, the following subunits combine to formnearly 80% of the GABAAR combinations in the rat brain: α1-3, ... McIntosh TK: Workshop of animal models of traumatic brain injury. J Neurotrauma 1994, 11:723-732.30. Hamm RJ, O'Dell DM, Pike BR, Lyeth BG: Cognitive impairment following traumatic brain...
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Báo cáo y học: "Safety of rFVIIa in hemodynamically unstable polytrauma patients with traumatic brain injury: post hoc analysis of 30 patients from a prospective, randomized, placebo-controlled, double-blind clinical trial" pps
... et al.: EBICguidelines for management of severe head injury in adults.Acta Neurichir 1997, 139:286-294.20. Vincent JL, Berré J: Primer on medical management of severe brain injury. Crit Care ... N, Singh D, Varma N, Mathuriya SN:Change in tissue thromboplastin content of brain followingtrauma. Neurol India 2005, 53:178-182.35. Stein SC, Smith DH: Coagulopathy in traumatic brain injury. Neurocrit ... Rates of hos-pitalization related to traumatic brain injury – nine states, 2003.MMWR Morb Mortal Wkly Rep 2007, 56:167-170.2. Hoyt DB: A clinical review of bleeding dilemmas in trauma.Semin...
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Báo cáo y học: " The costs of traumatic brain injury due to motorcycle accidents in Hanoi, Vietnam" doc
... strategic in mini-mizing the loss of household income by selectingTable 1: One-year costs associated with treatment by level of traumatic brain injury (Unit: USD, 1USD = 15,850 Vietnam dong)Level of ... first year post -injury, of non-fatal traumatic brain injury (TBI) in motorcycle users not wearing helmets in Hanoi, Vietnam. The costs arecalculated from the perspective of the injured patients ... post -injury at the time of interview.While all patients shared the same disability weight of zero pre -injury, the disparity post injury reflected the level of severity (Figure 2). In term of intangible...
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Báo cáo y học: " Pentobarbital versus thiopental in the treatment of refractory intracranial hypertension in patients with traumatic brain injury: a randomized controlled trial" ppsx
... (n)Thoracic injury 7 2 0.13Abdominal injury 4 1 0.34Extremities injury 9 5 0.20Admission CT (n)Diffuse injury without brain swelling 12 4 0.046Diffuse bilateral brain swelling 6 12Diffuse ... and thiopental in terms of controlling refractory intracranial hypertension in patients with severe traumatic brain injury, and to evaluate the adverse effects of treatment.Methods This was a ... 14Pre-enrolment CT (n)Diffuse injury without brain swelling 8 5 0.04Diffuse bilateral brain swelling 1 8Diffuse injury unilateral brain swelling with midline shift 5 1Any mass lesion evacuated 7 5Nonevacuated...
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Báo cáo y học: "Propofol: neuroprotection in an in vitro model of traumatic brain injury" pot
... agent in different in vitro models of brain injury induced by oxygen and glucose deprivation. We examined itsneuroprotective properties in an in vitro model of traumatic brain injury. Methods In ... model of traumatic brain injury. Introduction Traumatic brain injury (TBI) is a common consequence of traf-fic-related accidents and incidents at work and at home. Theannual incidence of TBI in ... in vitromodel of brain injury. Brain Res 2004, 1001:125-132.12. Morrison B 3rd, Eberwine JH, Meaney DF, McIntosh TK: Trau-matic injury induces differential expression of cell deathgenes in...
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