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leptin signaling pathways in cns and the regulation of energy balance

báo cáo hóa học:

báo cáo hóa học:" Force-feedback interaction with a neural oscillator model: for shared human-robot control of a virtual percussion instrument" doc

Hóa học - Dầu khí

... follow the green ball, we reasoned that in attempting to so, they would be successful in stopping the oscillator and could gain further insight into the dynamics of the task, reducing the training ... scribe their experience Since the subjects had been instructed to attempt to follow the green ball for NF–HINT during the training phase, they initially gained some intuition into the difficulty and ... always in the following order during the training phase: NF–HINT to immediately provide insight into an optimal strategy, followed by NF, MED, WEAK, and STRNG During the testing phase, each of the...
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Báo cáo khoa học:

Báo cáo khoa học: "Gene expression profiling of human dermal fibroblasts exposed to bleomycin sulphate does not differentiate between radiation sensitive and control patients" pptx

Báo cáo khoa học

... One of the main limitations of the study was the sample size This and the related issue of inter-sample variation may have contributed to the negative findings An additional possible source of ... conceiving the case control design and participated in the study design CMI participated in the study design and study coordination All authors read and approved the final manuscript Competing interests ... for TGF-beta1 and bleomycin intracellular signaling through autocrine regulation of Smad binding to the proximal promoter of the Smad gene J Cell Biochem 2006, 97(5):933-939 13 Rubin P, Johnston...
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Experimentation, modeling and control of calcium dynamics in human vascular endothelial cells

Experimentation, modeling and control of calcium dynamics in human vascular endothelial cells

Y - Dược

... to step into the world of mechanobiology in the very beginning In the subsection below, another version of statement is provided from a more engineering perspective 1.1.2 Views of Engineers Here ... substances in one signaling pathway will increase the difficulty in experiment and sometimes may bring unnecessary measurement error 1.3 Thesis Objective and Outline In this thesis, an engineering approach ... biological/physiological and engineering perspectives Proficient skills in handling cells and chip In our case, we need to integrate cell culture, ATP release measurement and Ca2+ imaging into the one system The main...
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Báo cáo y học:

Báo cáo y học: "Expression of Human Globular Adiponectin-Glucagon-Like Peptide-1 Analog Fusion Protein and Its Assay of Glucose-Lowering Effect In Vivo"

Y học thưởng thức

... http://www.medsci.org Int J Med Sci 2011, we connected the N-terminus of globular adiponectin and the C- terminus of GLP-1-A through the linker, which could make the N-terminus of GLP-1-A and the C-terminus of ... Purification and refolding of N-terminal His-tagged gAd-GLP-1-A fusion protein The fusion protein was purified by High-Affinity Ni-IDA Resin After filtering, the fusion protein was bound in the column The ... protein, we introduced an enterokinase cleavage site at the 5’ terminus of the gene of gAd-GLP-1-A fusion protein, which was used to remove the N-terminus His-tag [9] The gene encoding the gAd-GLP-1-A...
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Báo cáo y học:

Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"

Y học thưởng thức

... pravastatin to the total amount of that added during the entire loading process Cell recovery The percentage ratio of the hematocrite value of the final loaded cells to that of the initial packed ... of PBS containing the known concentration of the drug and 2.5 mmol of ATP, 2.5 mmol MgCl2 and 2.5 mmol of CaCl2, gently mixing to avoid hemolysis and incubation for 15 http://www.medsci.org Int ... including inhibition of the metabolism [5], administration of statins with certain juices [6] or inhibition of Pgp [3] Unfortunately these strategies are frequently associated with increase the...
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Báo cáo y học:

Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"

Y học thưởng thức

... consider because they are not hydrolysed by β-glucosidases in the intestine and can be administered orally [27] Therefore, the aim of the present study was to evaluate the inhibitory effect of some thioglycosides ... hydrolysis-resistant, synthetic S-analogs of natural O-glucosides involved in the biosynthesis of chrysomelidial and salicin These substances are synthesized and secreted as part of a defense mechanism ... phosphate-buffered saline (PBS; Invitrogen, Karlsruhe, Germany) and then incubated with 0.1 ml of a solution containing µM CC2-DMPE and 0.02% pluronic acid in PBS After in- cubation in the dark for 30...
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Báo cáo tiếng anh Ngoại thương Strategies of human resource development of MISA JSC.doc

Báo cáo tiếng anh Ngoại thương Strategies of human resource development of MISA JSC.doc

Quản trị kinh doanh

... MISA software into teaching job MISA is also the partner of Departments; Ministry, such as Ministry of Science and Technology; Ministry of Education and Training; Ministry of Foreign Office, and ... rules and workplace culture of the company In this period of probation, the company evaluates candidates that mainly based on sense of responsibility and inquiring mind of them In this step, the ... and Training, Minister of Information and Communication, Chairman of Accounting and Auditing of Vietnam, etc are clear proofs for exertion of MISA MISA’s software is used popularly in the whole...
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Báo cáo y học:

Báo cáo y học: "Low temperature tolerance of human embryonic stem cells"

Y học thưởng thức

... culture within bioreactors Conflicts of interest The authors have declared that no conflict of interest exists References Becker EW The roles of ATP in the dynamics of the actin filaments of the cytoskeleton ... Inc, St Louis, MO, USA) constituted in PBS, to each well (4.8 cm2) of the 12-well dish, following by incubation for h at 37 °C in the dark After incubation, the MTT solution was removed and the ... sealed at the sides with parafilm (for minimal evaporation), and placed in either a 4oC refrigerator, or back into the incubator reset at 25oC An atmosphere of 5% CO2 was maintained only for the physiological...
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Báo cáo y học:

Báo cáo y học: "Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors"

Y học thưởng thức

... in the other Animals in the other group received an injection of [E1-,E2b]ADGFP&hBMP4 in one thigh and an injection of ADhBMP4 in the other Each injection contained × 1010 particles The SD rats ... vivo The expression of viral proteins in infected target cells may increase the host immune response and further interrupt the expression of the foreign gene [12] To limit the productions of potentially ... diseases in the human clinical setting Besides the aforementioned major findings of this experiment, accurate gene sequencing is also a critical factor in the determination of the fate of gene...
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Báo cáo y học:

Báo cáo y học: "Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary"

Y học thưởng thức

... abnormalities not represent a single pathological entity and therefore there is no single strategy for their prevention Conflict of interest The author has declared that no conflict of interest exists References ... Previously the selective abortion, i.e termination of pregnancy after the prenatal diagnosis of severe fetal defects was also named as secondary prevention Recently the WHO and other international ... excluded this approach from the term “prevention” In Hungary about 20% of major congenital abnormalities (8.7% in the total group) were terminated after the prenatal diagnosis of defects Tertiary prevention:...
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Báo cáo y học:

Báo cáo y học: "ene expression analysis of human red blood cells"

Y học thưởng thức

... RBCs encoding initiation, activation and regulation of transcription and translation (for instance RNA polymerises I,II,III, zinc/PHD fingerDNA-binding proteins, cysteinyl, lysyl-tRNA synthetase), ... 19 The finding of RNA in anucleate cells like erythrocytes support the idea of nucleus independent protein synthesis and supports data 20 about possible mechanism of globin m-RNA stability in ... Further experiments are needed to understand the mechanisms and the biological meaning of these findings But gene expression profiling of human erythrocyte could be an important key for understanding...
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Control of Membrane Fouling by Coagulant and Coagulant Aid Addition in Membrane Bioreactor Systems

Control of Membrane Fouling by Coagulant and Coagulant Aid Addition in Membrane Bioreactor Systems

Môi trường

... on the biopolymer removal On the other hand, the mixture of Fe(III) and polysilicate worked more effectively on protein and carbohydrate removal The removal amount increased according to the ... concentrations The mixing duration (15 minutes) was decided from the results of kinetic batch experiments The pH of all solutions of the batch experiments were controlled to 7.0 using HCl and NaOH ... 105 oC for 30 minutes (Nakajima and Mishima, 2005) For the SMP
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Development of DMC controllers for temperature control of a room deploying the displacement ventilation HVAC system

Development of DMC controllers for temperature control of a room deploying the displacement ventilation HVAC system

Môi trường

... Harbin Institute of Technology, China in 2007 He is now pursuing his PhD degree in the same department in Harbin Institute of Technology and studying as a joint student in department of Mechanical ... PhD degree in control science and engineering from Harbin Institute of Technology, China in 2005 He was a Research Associate in the department of Mechanical Engineering the University of Hong Kong ... [60s/step] Figure The input signal and the step responses According to the superimposition principle of the linear system, suppose the original output value of the system at k is y0 (k), the control...
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THE INFLUENCE OF HUMAN ACTIVIES ON THE ENVIRONMENT

THE INFLUENCE OF HUMAN ACTIVIES ON THE ENVIRONMENT

Tiếng anh

... Improvements in agriculture health and medicine have produced a dramatic rise in the human population This increase in population size leads to an increase in pollution and higher demand for the world’s ... while other plants are killed Sulphur dioxide will dissolve in rain producing Acid Rain • Acid rain damages trees and pollutes rivers and lakes Acid rain causes erosion of buildings and statues ... problems Burning the timber increases the level of carbon dioxide in the air Less trees means less carbon dioxide absorbed for photosynthesis Soil is eroded as it is exposed to the wind and rain Less...
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BIOS Takes Control of the UHCI Host Controller

BIOS Takes Control of the UHCI Host Controller

Công nghệ thông tin

... Frame (SOF) tokens on the USB This article examines the third step of the process—taking control of the host controller in the context of providing a solution to the problem of legacy keyboard and ... article The operating system/BIOS handoff of legacy keyboard and mouse support is a twoway process In other words, the handoff can occur from the BIOS to the operating system or from the operating ... interface in implementing the handoff of the host controller between the operating system and the BIOS; the Microsoft host controller driver implementation logic is described in this section of the...
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The Potential of Biofumigants as Alternatives to Methyl Bromide for the Control of Pest Infestation in Grain and Dry Food Products

The Potential of Biofumigants as Alternatives to Methyl Bromide for the Control of Pest Infestation in Grain and Dry Food Products

Sinh học

... phosphine is a quick and effective tool for the control of stored-product insect pests In view of the scheduled phaseout of methyl bromide under the Montreal protocol, the role of phosphine in grain ... of all oils tested The main component of one of the oils is pulegone The other is not yet identified and it is called SEM76 (Shaaya and Kostyukovsky, 2006) In our study of the mode of action of ... evaluate the toxicity of allyl ITC in grain, we could show that 20 μL·L−1 air (=20 g m−3 ) and exposure time of day were not effective in killing the insects at the bottom of the column when the fumigant...
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Alternative Processing Technologies for the Control of Spoilage Bacteria in Fruit Juices and Beverages

Alternative Processing Technologies for the Control of Spoilage Bacteria in Fruit Juices and Beverages

Môi trường

... 90% of their energy at a wavelength of 253.7 nanometers Exposure of bacteria to UV results in cross-linking of the thymine dimers of the DNA in the organism, preventing repair of injury and reproduction ... growing of fruit, harvesting, postharvest handling, washing, and cooling and storage PREVENTIVE MEASURES IN THE ORCHARD Contamination of fruits with feces of animals such as deer,8 seagulls,9 and ... repair of DNA The use of combination treatments is expected to be more effective both in eliminating pathogens and in retaining quality attributes of the product.49 MICROWAVES The use of microwaves...
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Control of Cell Proliferation and Growth byMyc Proteins

Control of Cell Proliferation and Growth byMyc Proteins

Môi trường

... that the balance of expression of members of the Myc/Max/Mad network of proteins (see Fig 1) may dictate the response to loss of Myc (Walker et al 2005) In mice, the effects of deletion of the ... deletion of c-myc leads to a transient failure to form normal numbers of crypts in the small intestine, but in long-term experiments the mice maintain a normal epithelium in the absence of c-Myc ... genes of Myc contribute to the phosphorylation of the retinoblastoma protein and the regulation of E2F-dependent transcription Cyclins D1 and D2 have been suggested to be downstream targets of the...
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Electronics - Digital Control of Switching Power Supply

Electronics - Digital Control of Switching Power Supply

Cơ khí - Chế tạo máy

... environmental variations, and fewer part counts [2] It also reduces the size of the power supply by containing the complexity of control system within the software Therefore, since digital control ... number of parts required in the system and their susceptibility to aging and environment variations, which lead to high cost of maintenance Further, analog control once designed is inflexible and ... the corresponding standards in Europe and North America several active solutions have been proposed [2] and widely studied in the literature, being most usually employed the boost converter The...
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