laboratory animals and in vitro test systems used in regulatory toxicology

ROUTLEDGE STUDIES IN SCIENCE, TECHNOLOGY AND SOCIETY: Human-animal relations and the rise of veterinary medicine pot

... problem of maintaining animal resources and protecting human health and economy This notion is central to my discussion and is intended to epitomise and encapsulate the growing and increasingly formalised ... all In recent years, for example, health concernshave increasingly led to an apparent decline in the consumption of red meat and an increase in poultry and fish eating Furthermore, an increasing ... is commonly used to perform this task Similarly, wine production also involves fining: isinglass, gelatine, egg albumen, casein, chitin (from the shells of crabs and lobsters) and, in the past,...

Báo cáo khoa học: Natriuretic peptide system: an overview of studies using genetically engineered animal models doc

Danh mục: Báo cáo khoa học

... consequently results in an increase in the GTPase activity of the a subunit of the guanine nucleotide binding protein (Gaq) and in a decrease in the activity of the downstream signaling mediators (adapted ... were used to determine whether pharmacological inhibition of GC-A would increase calcineurin activity, which it did not [45] On the other hand, stimulation of GC-A with ANP inhibited calcineurin ... angiotensin II [29] and catecholamines [30] Interestingly, the baseline levels of ANP and BNP were not higher in the C-receptor-deﬁcient mice than in the wild-type mice, implying that either the...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 1 pptx

Danh mục: Tâm lý - Nghệ thuật sống

... Standing Moral standing indicates those individuals that moral agents must respect in certain separately determined ways In Western countries all human beings are assumed to have moral standing ... guidelines demonstrate moral standing—the individual, though to be killed, must be managed (and killed) in a certain manner In contrast, it has been and remains common in the West to deny moral standing ... that having interests is synonymous with having inherent value If something can be in an entity’s interest, then that entity has inherent value: “A sentient being has intrinsic value in that...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 2 pot

Danh mục: Tâm lý - Nghệ thuật sống

... fields is critical both to determine and to support any given moral outlook, but incorrect information can be misleading Diligence in exploring and incorporating information from outside the field ... which (1) they pursue and obtain what they prefer, (2) they take satisfaction in pursuing and obtaining what they prefer, and (3) what they prefer and obtain is in their interests (Case 117) An animal ... sufficient genes and proteins to maintain themselves” (Margulis 23–24) Yet even the smallest cells, those of the tiniest bacteria, are selfmaintaining entities, and thereby qualify as living entities...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 3 pps

Danh mục: Tâm lý - Nghệ thuật sống

... plainly stated intent and the whole point of utilitarianism Singer does not wish to increase but to decrease suffering by maximizing the satisfaction of interests “Singer is in favor of increasing ... possibilities embedded in Singer’s replaceability argument These surprising outcomes appear to stem from errors in Singer’s reasoning In “Killing Humans and Killing Animals Singer examines two utilitarian ... death and suffering Singer asserts that the ethics involved in killing are “much more complicated” than the morality of in icting suffering (Singer, Animal 228) For Singer, pain is pain, but the harm...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 4 pptx

Danh mục: Tâm lý - Nghệ thuật sống

... intentions and aims must be directed toward not interfering with or harming animals and plants in natural ecosystems and to preserving their wild status for their sake Having those aims and intentions ... undesirable intrusion into the natural world c Fidelity Fidelity forbids gaining an entity’s trust in order to deceive and gain advantage for immoral reasons We are required to maintain integrity in our ... Regrettably, Taylor indicates, this is sometimes necessary He points to the hunting of whales and seals in the Arctic and the hunting of wild goats and sheep in mountainous regions In these cases,”...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 5 pptx

Danh mục: Tâm lý - Nghệ thuật sống

... man and woman: And God said, “Let the earth bring forth living creatures of every kind: cattle and creeping things and wild animals of the earth of every kind.” And it was so God made the wild animals ... all things in him, things in heaven and things on earth (Eph 1:9–10) 246 chapter five [F]or in him all things in heaven and on earth were created all things have been created through him and ... creatures of God Linzey asserts that a good and loving God must remain morally responsible for and invested in every sentient being: “[A] redeeming God could not eschew the sighing and suﬀering of all...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 6 pps

Danh mục: Tâm lý - Nghệ thuật sống

... themselves in every other living being, and to see every other living being in themselves Inasmuch as Indians see God in humanity, they must also find the divine in anymals “Hindu belief in the cycle ... shining stars!/Praise him, you highest heavens, /and you waters above the heavens! /Mountains and all hills,/fruit trees and all cedars!/Wild animals and all cattle,/creeping things and flying ... “causes injury to many beings [T]he wooden implement with iron point injures the earth and the beings living in the earth” (Embree, Hindu 94) For many Indians, profiting from anymal suffering is...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 7 pdf

Danh mục: Tâm lý - Nghệ thuật sống

... process “binds all things into one, equalizing all things and all opinions” (Chan 177) Nothing lies outside of this Daoist continuum, and so “the chain of being is never broken,” and a link can ... not fish or hunt and thereby harm and kill living beings You should not in winter dig up hibernating animals and insects You should not use cages to trap birds and [other] animals (Schipper ... skins of wild animals, against target practice on living creatures, and against inciting animals to fight for human entertainment A well-known Hadith story about a woman condemned for confining and...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 8 potx

Danh mục: Tâm lý - Nghệ thuật sống

... human being is not viable, even if a human being feels no pain and has no brain waves, even if a human being is terminally ill and in terrible pain, and even if a human life can only be maintained ... distinguishes between being interested in (active), versus something being in one’s interest (passive) (Narveson, Nature 22) Children are often interested in things that are not in their interest; ... her interests should receive” (249) Philosophers (including Regan and Singer) tend to include consciousness in their assessment of moral standing, generally favoring anymals with larger brains and...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 9 doc

Danh mục: Tâm lý - Nghệ thuật sống

... captive breeding, a long-standing ethic of minimizing interference and minimizing harm would likely have assured the continuance of the Maori as well as that of endangered and extinct species ... chapter nine 458 to use their skins Inasmuch as we must have something to cover our bodies against the sun and the cold, we must minimize harm in securing our needs Killing low on the food chain minimizes ... research involves paralyzing cats with drugs, collapsing their lungs, inserting electrodes into their brains, and locking them into a stereotaxic frame Wilson inserts tubes, electrodes, and transducers...

In Search of Consistency: Ethics and Animals [Human–Animal Studies] Part 10 pptx

Danh mục: Tâm lý - Nghệ thuật sống

... Expanding review and future directions 503 moral standing to include other life-forms is inevitable Even if we exclude certain human beings, and even if we fail to protect human beings in certain ... You, and all other organisms, are continuous systems of material ﬂux, of matter moving in, playing a role, and moving out You are more like a candle ﬂame or a whirlpool than like a washing machine ... seemingly bizarre) realization that everything must be given moral consideration (Birch 318) In light of a comparatively inclusive dominant ethic concerning human life and moral standing, and in...

Báo cáo y học: "Stress and Childhood Asthma Risk: Overlapping Evidence from Animal Studies and Epidemiologic Research" potx

Danh mục: Báo cáo khoa học

... levels may influence the fetal immune system development and lead to an increased risk of atopic disorders, as conceptualized in Figure In preliminary analyses in our laboratory, we examined the ... also influence etiology.76 In parallel, chronic stress has been linked to asthma symptoms in cross-sectional population studies77 and in prospective studies linking caretaker stress to infant ... gene expression and elevates blood pressure in the adult offspring in the rat Neuroendocrinology 1986;39: 1299–305 41 Egliston K-A, McMahan C, Austin M-P Stress in pregnancy and infant HPA axis...

case studies in small animal diagnostic imaging

Danh mục: Tổng hợp

... gastrointestinal tract Gastro-intestinal wall thickening and layering, degree, symmetry and distribution of gastrointestinal wall changes, echogenicity of the mucosa, gastrointestinal motility and regional lymph ... differentiating inflammatory intestinal lesions from intestinal tumours Vomiting, diarrhoea (often chronic), melena, anorexia, abdominal pain, weight loss and lethargy are the most common clinical ... polyuro-polydypsia, inappropriate behaviour and central nervous system signs, including stargazing, staring into walls or corners, random barking, intermittent blindness, pacing, circling, seizures...

the animal painter social studies

Danh mục: Anh ngữ cho trẻ em

... carry her paint and paper She goes to a park to paint a big bird There are other birds to paint at the park Sandra sells her paintings for some money People buy Sandra’s bird paintings Sandra is ... you,” Sandra says Te a c he rR Think Critically ea Why does Sandra have a bag? What is the story mostly about? What happens to Sandra’s paintings? Why you think people buy Sandra’s paintings? ... or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher...

Development of a MACS based strategy for isolating rare cell populations from animal tissue for transcription factor studies

Danh mục: Thạc sĩ - Cao học

... isolate Pax2 expressing cells by FACS from the mid-hindbrain of mice, so that the role of Pax2, known to be involved in mid-hindbrain boundary patterning, can be elucidated in detail (Bouchard, ... technique, the long history and extensive utility of MACS in the clinical setting is a testament to its reliability and scalability in most instances Observations from the clinical applications of ... experimental findings ATP-binding cassette transporters serve a transport and regulator function and have been implicated in lipid disorders such as cardiovascular disease, because of their role in the...

Pentachlorophenol: Toxicology and Environmental Fate

Danh mục: Môi trường

... of methaemoglobin In case of chronic exposure: Immunoglobulin A and G 8.3.1.2 Urine Total protein and qualitative testing for haemoglobin Total porphyrins and delta-aminolevulinic acid 8.3.1.3 ... Radiographic examination of lungs should be routine in these cases Skin contact: Remove all contaminated clothing, including shoes and socks Wash skin and hair with soap and water Treat burns and skin lesions ... the main active ingredient in certain wood preservatives used in the home, and is added to products such as stains and paints Cases of apparent PCP intoxications after indoor application in homes...

saving land for animal

Danh mục: Kỹ năng viết tiếng Anh

...

Polish Journal of Environmental Studies

Danh mục: Môi trường

... quicker and more specific methods, including bioindicatory systems enabling determination of changes taking place in ecosystems and particular organisms The use of biological material, combined ... taining excessive amounts of nitrates In laboratory animals nitroso-amines cause hepatocellular damage and produce teratogenic, mutagenic and cancerogenic effects [3] Living organisms are used ... others, in the inhibition of estrogenic receptor synthesis The main source of PCBs are food products, and their accumulation in fatty tissue starts as early as during intrauterine life, and continues...

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Báo cáo y học: "Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators"

Danh mục: Y học thưởng thức

... each intravenously Doripenem was infused over one hour in study and over four hours in Page of 10 study In study 1, the comparator was piperacillin/ tazobactam 4.5 g every six hours infused over ... needed to confirm these preliminary findings and to define the clinical and economic value of doripenem in patients with VAP Key messages • Initial doripenem use in patients with VAP was associated ... 13 days) and ICU stay Page of 10 (median, 13 versus 21 days) in the subset with P aeruginosa at baseline • The economic findings from this paper, combined with previous clinical findings, suggest...

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