... mg of the tetrazine deri-vatized twofold with dansyl, was dissolved in a few drops of DMSO and then added to the reaction product of A. The Discussion Here we demonstrate the synthesis of ... ml chloroform and kept on ice. Then, with continuous stirring, a mixed solution of 20 ml chloroform and 0.144 mol chloride acetic acid tert-butyl ester 7 was added over a pe-riod of 90 minutes. ... temperature of 4°C. Int. J. Med. Sci. 2010, 7 http://www.medsci.org 222try”, instead of using conventional PNA harboring nucleobases. The multifaceted spectrum of applica-tions of Click...
... conjunction of these two sets of results into aprojectivist “analysis” of a thick ethical concept in any meaningful sense of “analysis.” This would be, putatively, an analysis of the original grasp of ... ethical equivalent of a “view from nowhere” in whichawareness of a set of alternative complete schemes of ethical concepts makesa return to any particular point of view an exercise of bad faith. ... support a general view of scepticism as an engine of ethical change andas properly taking the form of a particular kind of critique of our ethicalideas. That particular form of critique would be...
... participation of every employee in the processes of creationand transmission of knowledge. This study analyzes the implementation of an innovation andKM strategy in the Irizar company, a maker of luxury ... teamshave contributed to the creation of a shared view of the firm’s problems and to a simple transmission of knowledge. Because of their importance, the par-ticipation of worker is massive, although ... characterize this type of strategy. Itis remarkable how this cycle, especially the creation of knowledge, is closely related to innovation. Thecreation of new knowledge and of innovationsimplies...
... Leu23 of the CT -extension of the rmErv-C+CTmolecule witha minimum distance of 1.9 A˚between two atoms of the two leucines (Fig. 8A). Because the Leu23 residue of the CT -extension of the ... the extension peptide blocks some of the unprimed sub-sites of the enzyme (Fig. 7). The interface area of theCT -extension and the mature catalytic domain is1037 A˚2, which is 56% of the ... Theenzyme with the extension shows autocatalytic zymogen activation at ahigher pH of 8.0, whereas deletion of the extension results in a more activeform of the enzyme. This CT -extension was not...
... even poorer inhibitor of PpPr, the effect of extend-ing this polypeptide at its N-terminus was also exam-ined. Introduction of the MK(H)7MQ extension at theN-terminal end of wild-type S. cerevisiae ... to the active site of the enzyme. This anchoring function of the extension residues may allow inhibitory sequences, which, byABFig. 5. MALDI-TOF mass spectrometry analysis of S. castellii IA3terminating ... acidson the surface of the enzyme, adjacent to the end of the active site cleft where the N-terminal residues of an inhibitory IA3helix would be expected to bind(Fig. 3A). Extensionof the inhibitory...
... strength of log-likelihood lies in handling low-frequency data. Inour experiments, none of the AMs was able to ex-tract a substantial number of collocations from theset of hapaxlegomena.AcknowledgementThe ... applied: Instead of examining only a small sample of -best can-didates for each measure as it is common practice,we make use of recall and precision values for -best samples of arbitrary size, ... either one of theannotators were considered TPs.The second set consists of PNV triples ex-tracted from an 8 million word portion of theFrankfurter Rundschau Corpus4, in which part- of- speech...
... make the notion oflexical accumulation complete: the former is to obtain lexical data of (almost) the same linguistic structure as the source, the latter is to create data of totally new linguistic ... lexical group comprises a number of LSs (real or virtual) that a user uses in a work, and a set of operations which he may need to do on them. A lexical group is thus a workstation in a lexical ... groups. A model of such an orgamzation is shown in the figure below. alo~ lex cal tnd ~ups LEXICAL SYSTEM physical supports real lexical sets virtual lexical sets lexical groups...
... yield a consistent set of findings or a general, non-controverslal theory. In this paper, we review the results of six experiments which form the basis of a model of ambiguity resolution ... knows that a person is much more likely to walk on the surface of a ship than on the surface of a pack of playing cards. Other types of contextual information can be brought to bear on ambiguity ... multiple sources of dlsamblguatlng information. Leaving aside vague or misleading cases, it is clear that all of these types of information yield the same outcome, assignment of the contextually-approprlate...
... seconds. B. Knowledge Constructs The fundamental knowledge constructs of the sys- tem are of two types: 1) static knowledge structures, or memory elements, which can be thought of as n- dimensional ... in terms of a theory of stratified natural language processing in which macro- level knowledge constructs, such as those used in a knowledge- based report generator, occur at one of the higher ... THE DOMAIN-SPECIFIC KNOWLEDGE REQUIREMENT TENET How does one determine what knowledge must incorporated into a knowledge- based report generator? Because the goal of a knowledge- based report...
... LEXICALKNOWLEDGE BASES Robert A. Ameler Natural-Lsngu.ge and Knowledge- Resource Systems SRI International Menlo Park, California 94025, USA A lexicalknowledge base is a repository of ... dictionaries, the full text of reference books, the results of statistical analyses of text usages, and data manually obtained from human world knowledge. A lexicalknowledge base is not intended ... intended to provide a means of economically integrating not only dictionary definitions, but other types of lexieal knowledge. The task of constructing a lexicalknowledge base is seen as a...
... piece of the problem. A manual codification of the lexicon is a prohibitive task, regardless of the framework adopted for semantic knowledge representation; even when a large team of knowledge ... field of computers. An important advantage of surface meaning is that makes it easier the acquisition of the semantic lexicon. This issue is examined in the next section. Acquisition ofLexical ... agent _of take put fred speech-action mental-action consistof hand foot source _of speech-action destination _of speech-action power human speed slow mass human Figure 2. Examples of...
... prior likelihoods ofof their rules.5.5 Operative ConclusionsOur findings highlight the currently limited re-call of available resources for lexical inference.The higher recall of Lin’s resources ... in seman-tic inference, as the meaning of one term is of- ten inferred form another. Lexical- semantic re-sources, which provide the needed knowledge for lexical inference, are commonly utilized ... expansion using lexical- semantic relations. In Proceedings of SIGIR.566a lexical entailment resource, following an oper-ative rationale: a rule e’ ⇒ e should be includedin an entailment knowledge...
... CDAY 16 – PROTOCOL A Vs CDAY 11 – PROTOCOL CDAY 11 – PROTOCOL CSHELF LIFE EXTENSIONOF SHELF LIFE EXTENSIONOF TOMATOESTOMATOESShubham ChandraShubham ChandraPresidentPresidentChandra ... Test Results1. The CA films ensured the quality and freshness of tomato was maintained and permitted consumption even after 21 days of storage at 56˚F (13.3 ˚C). 2. Proved that designs with a ... Associates films (CA Film) generate a shelf life greater than that of design without films (control in air) at a storage temperature of 56˚F (13.3 ˚C). 10 Days After HarvestTOMATO TESTING RESULTSDAY...
... Frequency of amino acid residues in the flexible region of the C-terminal extensions of human and murine sHsps. Residues presentin the flexible region of the C-terminal extensionof each of the eight ... polarity of the C-termi-nal extension is reduced [25], and introduction of hydrophobicity into the C-terminal extension of aA-crystallin results in immobilization of the C-termi-nal extension ... part of anunstructured region, are not important for the determi-nation of this level of structure. In support of this con-clusion, mutants of aA- and aB-crystallin, in which theC-terminal extensions...
... compilation ª 2006 FEBSEffect of oculopharyngeal muscular dystrophy-associated extension of seven alanines on the fibrillation properties of the N-terminal domain of PABPN1Grit Lodderstedt1, ... debate.Huntington’s disease is one of the most prominentexamples of neurodegenerative diseases that are causedby trinucleotide expansions of CAG repeats and thusan expansion of a run of glutamine residues ... Fibril formation kinetics of N-WT. (A) N-WT was incubatedat a protein concentration of 1 mM in the absence (triangles) andpresence (circles) of 0.1% seeds (w ⁄ v). (B) Loss of monomericspecies...