epidemiologic review of head and neck cancers oral precancers and dietary risk factors in india
Bioactive Foods and Extracts ppt
... Ruano-Raviña, Mónica Pérez-Ríos, and Juan Miguel Barros-Dios viii Contents Chapter 30 Epidemiologic Review of Head and Neck Cancers, Oral Precancers, and Dietary Risk Factors in India 471 Mia ... daily intake of glucobrassicin and neoglucobrassicin (the two main dietary indole glucosinolates) was 22.5 mg per day in the United Kingdom 5.5 mg in Denmark, and 2.8 mg in Finland (IARC, 2004) In ... types contain glucobrassicin (3-indolylmethyl) and glucoiberin (3-methylsulfinilpropyl) and most contain substantial amounts of sinigrin (2-propenyl) For example, sinigrin, glucobrassicin, and glucoiberin...
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Báo cáo khoa học: "Clostridium septicum sepsis and colorectal cancer - a reminder" pptx
... benzylpenicillin and 500 mg of metronidazole were administered intravenously and gentamicin was discontinued following microbiology advice Intra operatively, a bulky inflammatory mass was identified in ... histology and is likely to have been the origin of the abdominal wound infection In view of this, vancomycin and metronidazole were used to treat sepsis Her condition remained critical and she died of ... gentamicin, benzyl penicillin and metronidazole for an intra abdominal cause of sepsis according to the hospital microbiology protocol The following day, she developed swinging pyrexia and blood...
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báo cáo khoa học: "Effective interventions to facilitate the uptake of breast, cervical and colorectal cancer screening: An implementation guideline." pps
... JM, on behalf of GIN Public [the Guideline International Network Patient and Poublic Invoement Working Group] Patient and public involvement in guidelines: international experiences and future perspectives ... screening and guideline development They were asked to complete questionnaire using a five-point scale targeting the quality of guideline (higher scores indicating better quality) and their intention ... responsible for the interpretation of the data; review of the draft versions of the manuscript; provision of feedback for important intellectual revisions; and review and final approval of the version...
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Báo cáo khoa hoc:"Polymorphisms within inflammatory genes and colorectal cancer" doc
... (nNOS), and inducible NOS (iNOS) NOS2A is the encoding gene for the inducible NOS It is required for the signalling process in the innate immunity [17] and it plays a central role on chronic inflammatory ... http://www.jnrbm.com/content/5/1/15 of biological activities (for a review see [19] and [20]) These activities encompass beneficial effects for the host in inflammation and in protective immune responses against a variety of infectious ... subunit (alpha) of a cytokine that is required for the T-cell-independent induction of interferon (IFN)-gamma IL-12 was believed to be unique in its ability to induce the differentiation of native...
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Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... http://www.medsci.org Int J Med Sci 2011, 41 Table Serum samples used in training and testing sets MALDI-TOF MS Samples Colorectal cancer Healthy volunteers Total Following binding and washing, the bound proteins ... Committee of Taizhou Municipal Hospital, and had the informed consent of the patients and volunteers The patients and serum samples were then divided into two groups: the ‘‘training’’ set and the blinded ... diagnosed according to combined clinical criteria, including Endoscopic examination of the colon, a combination of computed tomography (CT), positron emission tomography (PET), or both, and further...
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Tài liệu Bevacizumab and cetuximab for the treatment of metastatic colorectal cancer docx
... given in its current licensed indication either as a second-line treatment following failure of an irinotecan-containing regimen or as a subsequent-line treatment following failure of both irinotecan- ... (FOLFOX), and irinotecan plus infusional 5-FU/FA (FOLFIRI) Oral analogues of 5-FU (capecitabine and tegafur with uracil) may also be used instead of infusional 5-FU For those patients first receiving ... all new cancer cases in women and 14% of all new cancer cases in men The incidence of colorectal cancer increases with age In people between the ages of 45 and 49 years the incidence is 20 per...
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Nutrition and cancer: A review of the evidence for an anti-cancer diet pptx
... amount of SDG) After weaning the offspring mice were fed a regular mouse chow diet Researchers then examined the female offspring and found an increased number of terminal end buds and terminal ... County, Maryland Health Professional Follow-up Study Prospective study ↑Se = risk of advanced prostate cancer ↑Se = risk of gastrointestinal and prostate cancer Men in top quintile of serum γtocopherol ... Composite dietary profile (alcohol intake, methionine, folate, vit B12, B6) trend of increasing risk for high risk group ↑folate intake = ↓colon cancer (OR = 0.69); long-term use of multi-vitamins...
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American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer Prevention doc
... including lowering the risk of dying at an early age and lowering the chance of getting or dying from certain types of cancer Higher amounts of physical activity may be even better for lowering ... linked with an increased risk of colorectal cancer, and is probably linked to a higher risk of cancers of the pancreas, endometrium (lining of the uterus), and breast cancer (in women past menopause) ... increases the risk of some cancers far more than the effect of either drinking or smoking alone Regular intake of even a few drinks per week is linked to a higher risk of breast cancer in women Women...
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Báo cáo khoa học: MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells potx
... represents an increase of almost 100-fold in miR-143 expression in HCT116 relative to SW480 cells, thereby reinforcing the potential involvement of miR-143 in 5-FU sensitivity miR-143 and 5-FU down-regulate ... significant changes in pri-miR-143 levels, there was increased processing of pri-miR-143 into preand mature miR-143 [10] In addition, this DNA-damage-induced up-regulation of pre-miR-143 and mature miR-143 ... Isolated single clone-derived cell foci were picked up by ring cloning strategies, expanded and propagated in complete media plus G418 In addition, mixed populations of miR-143 overexpressing and control...
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Esophageal Cancer – Cell and Molecular Biology, Biomarkers, Nutrition and Treatment Edited by Ferdous Rastgar Jazii Published pdf
... most often is associated with an intrinsic tyrosine kinase activity, or by forming a complex with an intracellular tyrosine kinase [9] Following to binding of growth factors to their corresponding ... by activating Ras and MAPK MAPK signaling induces the expression of cyclins which bind CDKs and inactivate Rb Activation of Ras also induces growth inhibitory effectors including p16 and p15 Similar ... Activation of certain tyrosine kinase receptors, such as EGF receptors and HER2 (erbB-2) results in phosphorylation of catenins and prevention of their binding to cadherins [34-36] Regarding to this...
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Diet, nutrition and the prevention of cancer ppt
... the design and interpretation of such trials is given in the first IARC Handbook of Cancer Prevention10 Review of the role of diet in the aetiology of the major cancers Cancers of the oral cavity, ... overweight/obesity, limiting alcohol intake and increasing physical activity will reduce cancer risk, as will limiting consumption of Chinese-style salted fish and minimising dietary exposure to aflatoxin in populations ... doses of acrylamide increase the risk for several cancers, including cancers of the lung, mammary gland, thyroid and oral cavity In 2002, a Further reading International Agency for Research in Cancer...
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Nutrition and Physical Activity Guidelines for Gynecological Cancer Survivors ppt
... • • Overweight and obesity increase the risk of certain cancers amongst other common chronic diseases Risk of endometrial cancer increases with increased body fatness and abdominal fatness So, ... carrots and in dark green leafy vegetables Eating carrots has been shown to play a role in decreasing risk of cervical cancer To reap the most rewards of eating fruits and vegetables, eat them in ... that increased intake of red meat increases risk of endometrial cancer Red meat includes beef, pork, and lamb Choose lean cuts of red meat with little or no visible fat Lean meats provide protein,...
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Nutrition, Exercise and Prostate Cancer potx
... and stimulates production of insulin, which is linked to an increased risk of diabetes, heart disease, and prostate cancer Cutting back on sugar intake, maintaining a healthy diet, and engaging ... the effects of regular exercise Key Points to Remember Avoiding muscle loss and/ or gaining muscle through increased protein intake and exercise can help in achieving and maintaining a healthy ... cancer, including heart disease and diabetes 18 Building Strong Muscles Avoiding the muscle loss common in aging, inactivity, and hormonal therapies and/ or gaining muscle through increased protein intake...
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Classification of colorectal cancer based on correlation of clinical, morphological and molecular features doc
... uniform and linear sequence of steps, with APC inactivation initiating adenomas and additional genetic changes, notably KRAS mutation, and TP53 inactivation promoting the emergence of increasingly ... limitations of present-day biotechnology insofar as it is incapable of either explaining the evolutionary history of a malignancy or resolving subtle differences in levels of gene expression existing ... methylation of APC (leading to complete silencing) may not provide an important 115 growth advantage Invoking other components of the Wnt signalling pathway such as AXIN240 or TCF441 in the initiation of...
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colorectal cancer, methods and protocols
... Subheading 3.2 3.4 Staining of FFPE Histologic Sections for LCM (DNA Isolation) Perform steps 1–7 in Subheading 3.2 After staining in eosin, rinse in a 95% ethanol bath, then repeat rinse in ... P L., West, G A., Cominelli, F., Rachmilewitz, D., Klein, J S., and Fiocchi, C (1993) Localization of intestinal interleukin activity and protein and gene expression to lamina propria cells Gastroenterology ... ice-cold 70%, 85%, and 100% ethanol, for each, followed by air drying Add 10 µL of proteinase K into a prewarmed (37°C) coplin jar containing 100 mL of proteinase K buffer and incubate the slides...
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Báo cáo hóa học: " Comparison of T-cell receptor repertoire restriction in blood and tumor tissue of colorectal cancer patients" docx
... confirming the results of former studies investigating Vβ-repertoire restrictions in blood of patients with other tumor entities, which have been interpreted as indication for the induction of specific ... measurements and analyses NCN collected samples and participated in the conduct of the study ET participated in design and conduct of the study UK participated in design and conduct of the study ... receptor variable beta gene-restricted profile of CD8+ T lymphocytes in the peripheral circulation of patients with squamous cell carcinoma of the head and neck Clin Cancer Res 2006, 12:2394-403 43...
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Báo cáo hóa học: " LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer" pptx
... only in the front of invasion and 93 cases (58%) exhibited nuclear b-catenin positivity both in the tumour centre and in cells of the front of invasion The presence and distribution of LEF-1 and ... The DNA binding proteins and transcription factors TCF4 and LEF-1 are partners of nuclear b-catenin and effectors of the Wnt/b-catenin signalling pathway, which is decisively involved in tumorigenesis ... a higher risk of death of disease These results indicate different effects of the Wnt signalling pathway in vivo depending upon the nuclear binding partners of b-catenin Moreover both factors...
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Báo cáo sinh học: "Clinical outcomes of active specific immunotherapy in advanced colorectal cancer and suspected minimal residual colorectal cancer: a meta-analysis and system review" pdf
... grading scheme (A, B, and C) is used to classify four main aspects: 1) quality of randomization, 2) quality of allocation concealment, 3) quality of blinding, and 4) quality of the description of ... disease without evidence of remaining macroscopic disease) Clinical outcomes to evaluate ASI in suspected minimal residual CRC were OS and DFS, and clinical outcomes of ASI in advanced CRC were complete ... “rectal” AND “cancer” OR “carcinoma” AND vaccine “OR “vaccination” OR “immunization” Review papers were also examined for published results We avoided duplications of data by examining the body of...
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Báo cáo sinh học: "Protein kinase CK2a is overexpressed in colorectal cancer and modulates cell proliferation and invasion via regulating EMT-related genes" docx
... Meggio F, Pinna LA: One-thousand -and- one substrates of protein kinase CK2? FASEB J 2003, 17:349-368 11 Seldin DC, Lou DY, Toselli P, Landesman-Bollag E, Dominguez I: Gene targeting of CK2 catalytic ... http://www.translational-medicine.com/content/9/1/97 Cell lines and culture conditions The human colorectal cancer cell lines LoVo, SW480, HT29, HCT116 and LS174T were maintained in RPMI 1640 (Gibco, Grand Island, NY, ... E-cadherin and vimentin, in association with repression of the transcription factors snail1 and smad2/3 expression Knockdown of CK2a reversed the cytoplasmic-tonuclear transfer of b-catenin resulted...
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