efficient document similarity search
Tài liệu Báo cáo khoa học: Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide – interference with interferon-c-STAT1-mediated killing pdf
... assays. However, thesame cells were efficiently killed by interferon-c. This effect was counter-acted by the STAT3 oligodeoxynucleotide, which was found to efficientlyinhibit STAT1. Thus, although ... oligodeoxy-nucleotide was added to a colon carcinoma cell line in which it induced celldeath as efficiently as the STAT3 inhibitor stattic. The hairpin STAT3oligodeoxynucleotide co-localized with ... Efficient killing of SW480 colon carcinoma cells by asignal transducer and activator of transcription...
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Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt
... andK0.5= Km.AcknowledgementsThis work was supported by grants from the DanishResearch council and the Novo Nordic ResearchCouncil. The skilful technical assistance of MarianneLauridsen is gratefully ... as indicated by con-cave Hofstee plots of v versus v ⁄ s (insets to the kineticplots), Hill coefficients < 1 and high K0.5values(Table 1). All of the tetrameric forms showed approxi-mately ... the molecular mass, as the standard varia-tion in Ve⁄ V0for the markers was less than 2% (coefficientof variation) from 20 separate marker elution profiles.Fractions (200 lL) were collected...
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Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
... extracellularNa+concentrations. The solid lines represent fits of the Hill equa-tion with Hill coefficients of n ¼ 1.3 for the wild type GAT1 andn ¼ 1 for the mutants (as used previously by Liu ... synthesizedproteins in the ER. If N-glycosylation is inhibited,some glycoproteins fail to fold or assemble efficiently,resulting in a prolonged retention in the ER and anincreased proteolytic breakdown ... 7.2).AcknowledgementsThis work was supported in part by the Special Fundsfor Major State Basic Research of China (GrantG1999053907), a grant from the Chinese Academy ofSciences, a grant from...
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Tài liệu Efficient Pattern Matching over Event Streams doc
... that expands dur-ing event processing, the backtrack algorithm processes runsin a depth first search manner. That is, we process the sin-gleton run until it either fails or produces a result ... singleton run. Our basic algorithm, onthe other hand, expands the “run tree” in a breadth first search manner; it creates and evaluates all runs at once.5.3 Memory ManagementThere are a number ... window, calledthe pruning timestamp. We use the pruning timestampas a key to perform a binary search in each stack of the5Regular expression matching in network intrusion detection sys-tems...
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Tài liệu Báo cáo khoa học: Efficient RNA ligation by reverse-joined hairpin ribozymes and engineering of twin ribozymes consisting of conventional and reverse-joined hairpin ribozyme units ppt
... ribozymesthat are structurally optimized and which, in addition to cleavage, catalyse efficient RNA ligation. The most efficient variant ligated its appropriateRNA substrate with a single turnover rate ... substrateand the ribozyme seems to be most favourable foran efficient reaction among the studied species.HP–RJWTA7 is also an efficient endonuclease; itcleaves the substrate S40F3F5 with kobs¼ ... stability of the pro-perly folded substrate–ribozyme complex. Strikingly,the hairpin ribozyme is an efficient ligase if the ribo-zyme substrate complex is folded into a stable secon-dary and tertiary...
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Tài liệu Báo cáo khoa học: "Efficient Online Locality Sensitive Hashing via Reservoir Counting" ppt
... aprediction of a running sum being positive or negative.States are numerically labeled to reflect the similarity toa small bit integer data type, one that never overflows.transitions. Assuming a fixed ... June.Shane Bergsma and Benjamin Van Durme. 2011. Learn-ing Bilingual Lexicons using the Visual Similarity ofLabeled Web Images. In Proc. of the InternationalJoint Conference on Artificial Intelligence ... Linguistics (ACL).Thorsten Brants and Alex Franz. 2006. Web 1T 5-gramversion 1.Moses Charikar. 2002. Similarity estimation techniquesfrom rounding algorithms. In Proceedings of STOC.Michel X. Goemans...
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Tài liệu Báo cáo khoa học: "Computationally Efficient M-Estimation of Log-Linear Structure Models∗" doc
... 2003. Shallow parsing with conditionalrandom fields. In Proc. of HLT-NAACL.A. Stolcke. 1995. An efficient probabilistic context-free pars-ing algorithm that computes prefix probabilities. Computa-tional ... 752–759,Prague, Czech Republic, June 2007.c2007 Association for Computational LinguisticsComputationally Efficient M-Estimation of Log-Linear Structure Models∗Noah A. Smith and Douglas L. Vail and John ... (and decoding underthem) is tractable only when the model’s indepen-dence assumptions permit efficient inference proce-dures. For example, in the original conditional ran-dom fields (Lafferty...
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Báo cáo khoa học: A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis doc
... concentrations were determined spectropho-tometrically by absorbance at 280 nm, using an extinctioncoefficient of 0.98 for a 1 mgÆmL)1solution [35]. Coenzymeconcentrations were also determined spectrophotometricallyusing ... spectrophotome-ter) due to the production of NAD(P)H at 340 nm, using amillimolar extinction coefficient of 6.22 mM)1Æcm)1. All ratemeasurements were performed in triplicate and the resultsshown ... inhibition of glutamatedehydrogenase results from disruption of subunitinteractions necessary for efficient catalysisJaclyn Bailey1, Lakeila Powell2, Leander Sinanan3, Jacob Neal3, Ming...
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Báo cáo khoa học: Efficient and targeted delivery of siRNA in vivo pdf
... achieving efficient and targetedsiRNA delivery in vivo.AcknowledgementThis work was supported by NSF CAREER Award(DMR-0956091) and a Council on Research Comput-ing and Libraries Research Grant ... efficiencyvia efficient cytosolic release with high resistance toserum and low cytotoxicity [129]. It was demonstratedthat ketalized linear polyethylenimine ⁄ siRNA poly-plexes were efficiently ... silencingbecause they were entrapped in the endosomes evenafter efficiently entering cells [117]. Photostimulatingfluorescently labeled TAT efficiently released TAT–siRNA conjugates from the endosome,...
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Báo cáo khoa học: "Exploring Deterministic Constraints: From a Constrained English POS Tagger to an Efficient ILP Solution to Chinese Word Segmentation" ppt
... heuristics such as forward maxi-mum match (Sproat et al., 1996). Exact search ispossible with a Viterbi-style algorithm, but beam- search decoding is more popular as used in (Zhangand Clark, 2007) ... a beam (=5) search. on the development set, we set beam-width of ourbaseline model as 5. Our baseline model, whichuses Ratnaparkhi (1996)’s feature set and conductsa beam (=5) search in the ... deterministic constraints first be-fore a probabilistic search, i.e. for some words, thenumber of possible tags is reduced to 1, the search space is reduced to Tm, where m is the number of(unconstrained)...
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Báo cáo khoa học: "Efficient Third-order Dependency Parsers" pdf
... Linguistics,24(4):613–632.Tadao Kasami. 1965. An Efficient Recognition andSyntax-analysis Algorithm for Context-free Lan-guages. Technical Report AFCRL-65-758, AirForce Cambridge Research Lab.Terry Koo, Amir Globerson, ... ex-pressive third-order factorizations while retainingan efficient O(n4) runtime. In fact, our third-order parsing algorithms are “optimally” efficient in an asymptotic sense. Since each third-order ... has proven to be a very use-ful syntactic formalism, due in no small part to thedevelopment of efficient parsing algorithms (Eis-ner, 2000; McDonald et al., 2005b; McDonaldand Pereira, 2006;...
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Báo cáo khoa học: "Efficient Staggered Decoding for Sequence Labeling" pptx
... staggereddecoding efficiently performs the search step. Forthis purpose, we can basically use the Viterbi algo-rithm. In earlier iterations, the Viterbi algorithm isindeed efficient because the ... this idea to other NLP tasks is stillunclear.Approximate algorithms, such as beam search or island-driven search, have been proposed forspeeding up decoding. Tsuruoka and Tsujii (2005)proposed ... calculated in the search step. This can be done by retaining thebest path among those consisting of only activelabels. The score of that path is obviously thelower bound. Since the search step is...
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Báo cáo khoa học: "An Efficient Indexer for Large N-Gram Corpora" docx
... hence efficient ac-cessing of the N-gram frequencies becomes an is-sue. Trivial methods such as linear or binary search over the entire dataset in order to access a singleN-gram prove inefficient, ... given to be in order of a fewseconds. Other tools that implement a binary search algorithm as a simpler, yet less efficient method arealso given in (Giuliano et al., 2007; Yuret, 2007).3 The ... balanced search tree where eachnode has several children. Indexing large files us-ing B+trees is a popular technique implementedby most database systems today as the underlyingstructure for efficient...
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Báo cáo khoa học: "Efficient, Feature-based, Conditional Random Field Parsing" potx
... pieces of information. Firstly, eachword is annotated with a distributional similarity tag,from a distributional similarity model (Clark, 2000)trained on 100 million words from the British ... tenfold.3 Stochastic Optimization MethodsStochastic optimization methods have proven to beextremely efficient for the training of models involv-ing computationally expensive objective functionslike ... sev-eral passes through the data in order to satisfy suffi-cient descent conditions placed on line searches. Inour experiments SGD converged to a lower objectivefunction value than L-BFGS, however...
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Báo cáo khoa học: Efficient inhibition of b-secretase gene expression in HEK293 cells by tRNAVal-driven and CTE-helicase associated hammerhead ribozymes doc
... RNA after the 5¢-NHH-3¢sequence, where N is A, U, C or G and H is A, U or C[32], with the most efficient cleavage of the substratepossessing the triplet GUC or CUC [23]. The messengerRNA of ... interference(RNAi) phenomena [36,37]. The power of RNAi isremarkable, because it can serve as a very efficient sequence-specific tool for gene silencing. RNAi is a valuabletherapeutic tool for drug ... designed for endogenous generation of siRNA [40–44].As our tRNA-driven ribozyme transcripts are efficientlyexported from the nucleus to the cytoplasm, where they meettheir target mRNA, this expression...
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- efficient method of moments
- efficient method of moments emm
- renewable and efficient electric power systems
- an efficient and flexible c toolkit
- guibased efficient medline search tool
- efficient unsupervised discovery of word categories
- efficient inference of crfs
- efficient handling of uncertainty
- efficient minimum error rate training
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