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design synthesis screening and decoding of encoded one bead one compound peptidomimetic and small molecule combinatorial lib

High-Surface-Area Catalyst Design- Synthesis, Characterization, and Reaction Studies of Platinum Nanoparticles in Mesoporous SBA-15 Silica

High-Surface-Area Catalyst Design- Synthesis, Characterization, and Reaction Studies of Platinum Nanoparticles in Mesoporous SBA-15 Silica

Hóa học - Dầu khí

... Director, Office of Energy Research, Office of Basic Energy Sciences, Materials and Chemical Sciences Divisions of the U S Department of Energy under Contract DE-AC03-76SF00098 We thank Professor ... volume of acetone, and redispersed in water All Pt colloidal solutions were adjusted to × 10-3 M based on the Pt salt concentration by adding appropriate amount of deionized water 2.2 Synthesis of ... volume of 1.16 cm3 g-1 2.3 Preparation of Pt/SBA-15 Pt colloidal aqueous solution (25.6 mL, × 10-3 M) was mixed with 74.4 mL of water and 100 mL of ethanol The mixture was quickly added to 1.5 g of...
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stochastic modeling of manufacturing systems advances in design, performance evaluation, and control issues - g. liberopoulos

stochastic modeling of manufacturing systems advances in design, performance evaluation, and control issues - g. liberopoulos

Kế hoạch kinh doanh

... indicate that line A is one of (17), or one of (18), and one of (17) and (18), respectively Lines (17) and (18) are analyzed in Sections and for the cases of CVup = / CVdown and CVup = CVdown , respectively ... often have up- and downtime distributed nonexponentially As the empirical evidence (Inman, 1999) indicates, the coefcients of variation, CVup and CVdown of these random variables are often less than ... operation of the production line dened by assumptions (i)(vi) of Section Then, a set of representative distributions of up- and downtime was selected and, nally, for each member of this set, P R and...
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Macromolecular architectures based on well defined poly(pentafluorostyrene)  design, synthesis, characterization and applications

Macromolecular architectures based on well defined poly(pentafluorostyrene) design, synthesis, characterization and applications

Kỹ thuật - Công nghệ

... predictable and the polydispersity less 1.25 From then on, a series of gradient copolymers such as, of n-butyl acrylate and styrene, epoxystyrene and styrene, trimethylsilystyrene and styrene, and MMA and ... the components of copolymers, but also by the molecular structure of the copolymers Thus, the synthesis of amphiphilic block copolymers with well-defined molecular weights and the study of the ... macromolecules with a hydrophilic head of controllable dimension, consisting of designed length and number of PAAC brushes, and a hydrophobic PFS tail of controlled length were synthesized by...
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Nanoparticles of biodegradable polymers for controlled and targeted delivery of protein drugs and small molecule drugs

Nanoparticles of biodegradable polymers for controlled and targeted delivery of protein drugs and small molecule drugs

Tổng hợp

... NANOPARTICLES OF BIODEGRADABLE POLYMERS FOR CONTROLLED AND TARGETED DELIVERY OF PROTEIN DRUGS SMALL AND MOLECULE DRUGS BY LEE SIE HUEY (B.Sc (Hons.), NUS) A THESIS SUBMITTED FOR THE DEGREE OF MASTER ... polymer backbone of PLA and PLGA to form PLA-TPGS and PLGA-TPGS block copolymers These block copolymers are an example of amphiphiles Their uses as different carriers for delivery of protein and anticancer ... encapsulation of hydrophilic compounds This method enabled hydrophilic compounds to be partitioned into aqueous phase and hence decreases the contact between the organic phase and the hydrophilic compounds,...
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Báo cáo hóa học:

Báo cáo hóa học: "Facile Synthesis and Tensile Behavior of TiO2 One-Dimensional Nanostructures" doc

Hóa học - Dầu khí

... of a scanning electron microscope According to the knowledge of the authors, this is the first time that the tensile behavior of rutile TiO2 1D nanostructures is reported Materials Synthesis and ... Illustration of the effect of catalytic materials: the nanostructures were synthesized without (a) and with (b) catalytic material Ni at 850 °C for 60 Illustration of the effect of reaction temperatures: ... 750 °C (c) and 1050 °C (d) for 60 Illustration of the effect of reaction time: the nanostructures were synthesized at 950 °C for 15 (e) and 120 (f) Insets are low magnification images of as-synthesized...
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Design, synthesis and applications of Metal Organic Frameworks

Design, synthesis and applications of Metal Organic Frameworks

Kỹ thuật

... MOFs—namely synthesis of new ligands to expand the library of molecular building blocks for constructing MOFs as well as synthesis of MOFs from those ligands, investigation of several MOF systems ... the case of Cd MOF-1 and Cd MOF-2, they exhibit smaller channels then designed while remaining some degree of porosity Figure 34 Adamentine view of a single fold of framework of Cd MOF-2, which ... MOFs utilizing this family of ligands failed to yield any MOF We have successfully synthesized new MOFs utilizing 4-(imidazolyl) benzoic acid ligands: Cu MOF-3N, Cu MOF-4, Cu MOF-5 and Cd MOF-3...
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DESIGN, SYNTHESIS AND STUDY OF DNA-TARGETED BENZIMIDAZOLE-AMINO ACID CONJUGATES

DESIGN, SYNTHESIS AND STUDY OF DNA-TARGETED BENZIMIDAZOLE-AMINO ACID CONJUGATES

Y khoa - Dược

... WEIGHT COMPOUNDS 1.1 Overview The DNA minor groove has been an important focus of chemical and biological studies since the elucidation of the structure of DNA and an understanding of the role of ... 21 1.6 Plan of Study 23 v Page 1.7 List of References 25 CHAPTER DESIGN AND SYNTHESIS OF AMINO ACID-BENZIMIDAZOLEAMIDINE CONJUGATES 30 2.1 Design of Amino Acid-Benzimidazole-Amidine ... Research Integrity and Copyright Disclaimer Title of Thesis/Dissertation: Design, Synthesis and Study of DNA-Targeted Benzimidazole-Amino Acid Conjugates For the degree of Master of Science Choose...
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design, synthesis and photophysics of fluorescence turn-on conjugated polymer chemosensors

design, synthesis and photophysics of fluorescence turn-on conjugated polymer chemosensors

Tiến sĩ

... 142 Scheme 5-4 Unsuccessful synthesis of a-PPETE 142 Scheme 5-5 Synthesis of phth-PPETE 144 Scheme 5-6 Unsuccessful synthesis of a-PPETE 144 Scheme 5-7 Synthesis of thiourea group loaded thienyl ... spectra of tmeda-PPETE and dea-PPETE 51 Figure 2-7 Comparison of routine 13C NMR and 13C DEPT of dea-PPETE 52 Figure 2-8 2D Heteronuclear (C,H)-Correlated NMR of dea-PPETE 52 Figure 2-9 UV-Vis and ... enhancement of dea-PPETE in THF upon addition of metal cations 57 Figure 2-12 Emission and UV-Vis spectra of tmeda-PPETE upon addition of different concentration of Hg2+ 59 Figure 3-1 Structures of (x%-tmeda)-PPETEs...
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design, synthesis, and characterization of polymeric materials for uses in energy storage applications

design, synthesis, and characterization of polymeric materials for uses in energy storage applications

Tiến sĩ

... Sen Professor of Chemistry Head of the Department of Chemistry *Signatures are on file in the Graduate School iii ABSTRACT The work described in this thesis focuses on the design, synthesis, and ... Chapters and details work towards the synthesis and evaluation of highly selective membranes for use in lithium-seawater batteries The fifth chapter deals with the synthesis and characterization of ... poly(dimethylsiloxane) has a Tg of -130ºC and is known to be one of the most flexible polymer backbones in existance The low barrier to torsion of the phosphorus-nitrogen bond is best explained in terms of bonding...
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design, synthesis, and biological evaluation of new anti-cancer nitrogen-containing combretastatins and novel cysteine protease inhibitors for the treatment of chagas

design, synthesis, and biological evaluation of new anti-cancer nitrogen-containing combretastatins and novel cysteine protease inhibitors for the treatment of chagas

Tiến sĩ

... 8.10 Synthesis of α,β- conjugated ketone 82 207 8.11 Synthesis of thiosemicarbazones 84 and 83a 208 8.12 Bromination and further oxidation of 1,1-dioxo-1-thiochromen-4 -one 209 8.13 Synthesis of ... of compound 50 193 8.2 1H-NMR spectrum of compound 51a 194 8.3 X-ray structure of compound 59 197 8.4 X-ray structure of compound 66 202 9.1 Minimun energy conformations of compounds 59, 62 and ... Bromination of β-tetralone under two different conditions 203 8.7 Synthesis of bromothiosemicarbazone 69 203 8.8 Syhnthesis of thiosemicarbazone 74 204 8.9 Synthesis of α,β- conjugated ketones 77 and...
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DESIGN, SYNTHESIS AND PROPERTIES OF METAL COMPLEXES AND COORDINATION POLYMERS FOR 2+2 PHOTO CYCLOADDITION REACTIONS

DESIGN, SYNTHESIS AND PROPERTIES OF METAL COMPLEXES AND COORDINATION POLYMERS FOR 2+2 PHOTO CYCLOADDITION REACTIONS

Kỹ thuật - Công nghệ

... geometry of IV-1 with labels, H- 4-6 bonded chains, and packing of showing the alignment of 4spy ligands XVIII Figure 4-2 TGA and DTG of IV-1 4-7 Figure 4-3 4-10 H-NMR spectra of IV-2 before and after ... transformation and showed the transformation of 2D layered structure to 3D MOF Chapter describes design and synthesis of photoreactive 2D interdigitated CPs which were transformed to 3D interpenetrated MOFs ... particular C-Hπ and C-HX in solid state and their properties in solid state and their role in the design and synthesis of organic solids during his studies in the late 80’s and early 90’s showed...
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Design, synthesis and biological studies of coumarin based probes and tetrahydrolipstatin analogs 1

Design, synthesis and biological studies of coumarin based probes and tetrahydrolipstatin analogs 1

Thạc sĩ - Cao học

... Romo’s synthesis of THL 53 4.10 Hoffmann-La Roche enantiosynthesis of THL 54 4.11 Kumaraswamy’s synthesis of THL 56 4.12 Synthesis of β-hydroxy aldehyde 4.71 57 4.13 Davies’ synthesis of THL ... synthesis of THL 4.4 Kocienski’s synthesis of THL 48 4.5 Hanessian’s synthesis of THL 49 4.6 Ghosh’s asymmetric synthesis of THL 50 4.7 Mcleod’s synthesis of THL 52 4.8 Laglois’ synhesis of THL ... Synthesis of mono-Boc linker 16 2.5 Synthesis of flurescent RGDC conjugate 19 4.1 Schneider’s synthesis of THL 45 4.2 45 4.3 Hoffmann-La Roche second generation synthesis of THL Uskoković’s synthesis...
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Design, synthesis and biological studies of coumarin based probes and tetrahydrolipstatin analogs

Design, synthesis and biological studies of coumarin based probes and tetrahydrolipstatin analogs

Thạc sĩ - Cao học

... 125.7577890 MHz DATE_d : DECNUC : off NS 39.9955 39.8279 39.7551 39.6968 39.6603 39.4927 39.3324 39.1648 38.9972 38.8514 38.7057 BF1 : 137 Oct 23 2006 NUCLEUS : off PULPROG : zgpg30 SFO1 : 125.7709936 ... Parameters *** O sg1023~1 : *** Acquisition Parameters *** O 2.19 Oct 23 2006 : off NS O : DECNUC N : 125.7577890 MHz DATE_d : 57 off PULPROG : N H BF1 NUCLEUS : N H (1) N O : PROCNO 34.0345 33.9106 O ... MHz 1.00 Hz 32768 *** 1D NMR Plot Parameters *** O N H (1) 35.0 : SF 60 50 40 30 20 10 60.62 Hz off 220 39.6968 38.8514 38.7057 38.4506 34.0345 33.9106 69.5313 69.4875 68.9774 68.9556 97.4419...
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Design, synthesis and biological evaluation of inhibitors of flavivirus NS2B NS3 protease

Design, synthesis and biological evaluation of inhibitors of flavivirus NS2B NS3 protease

Cao đẳng - Đại học

... Scheme 4.1 Synthesis of compound 4-7 66 Scheme 4.2 Synthesis of compound 4-10 and 4-11 68 Scheme 5.1 Solution-phase Synthesis 101 Scheme 5.2 SPS of Pyrazolo[5,1-d][1,2,3,5]tetrazine-4(3H)-ones 103 ... which is the main focus of the thesis involves the design, synthesis and biological evaluation of inhibitors of Dengue and West Nile virus NS2B-NS3 protease For the design of dengue NS2B-NS3 protease ... mechanism of inhibition of WNV NS2B-NS3pro 76 by the (-) enantiomer of compound 4-6o Figure 5.1 Library of synthesized pyrazolo[5,1-d][1,2,3,5]tetrazine 105 -4(3H)-ones 5-1a-p ix LIST OF SCHEME...
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Design, synthesis and characterization of smart surfaces and interfaces

Design, synthesis and characterization of smart surfaces and interfaces

Cao đẳng - Đại học

... with a standard pore diameter of d=0.22 µm 12 Figure 5.1: Schematic illustration of the process of ozone-pretreatment and graft copolymerization of PVDF with inimer BIEA, preparation of “surfaceactive” ... solution of (a) the pristine PVDF, and the PVDF-gP4VP copolymers of bulk graft concentrations ([-4VP-]/[-CH2CF2-]bulk ratios) of (b) 0.038, (c) 0.068 and (d) 0.083 Figure 3.8: Effect of pH of the ... (a) UV-visible absorbance of aqueous solutions of PDMAPS of different concentrations as a function of temperature (b) UV-visible absorbance of aqueous solutions of PDMAPS of different electrolyte...
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DNA by Design. Stephen Meyer and the Return of the God Hypothesis

DNA by Design. Stephen Meyer and the Return of the God Hypothesis

TOEFL - IELTS - TOEIC

... Thaxton and Meyer commit a version of the genetic fallacy Moral dignity is a function of what virtues one has and how one comports oneself, not of how one came to be Similarly, moral rights (and ... ID theorists purport, and the suggestion of a conspiracy of silence is absurd One can find any number of discussions of the Cambrian radiation in the scientific literature, and new studies regularly ... complexities of subcellular machines as the best evidence of intelligent design None of these specific arguments is original with Meyer, however, and whenever he writes or speaks of them he relies...
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Tài liệu Báo cáo

Tài liệu Báo cáo " synthesis, cloning and expression in escherichia coli of a gene coding for Mcoti-ii " ppt

Báo cáo khoa học

... growth and mortality of insect pests, Plutella xylostella (PX) and Spodoptera litura (SL).17th International Congress of Biochemistry and Molecular Biology Annual Meeting of the American Society of ... the 58 kD protein band was found in induced sample as the major band, acounted for 80% of total protein (lane 1,3,5 and 6) 58 kD Fig 10 SDS PAGE pattern of PI-17 proteins Mc Standard molecular ... Wilusz T., and Laskowski M., Jr The squash family of serine proteinase inhibitors Amino acid sequences and association equilibrium constants of inhibitors from squash, summer squash, zucchini and cucumber...
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Large scale synthesis, characterization and photoluminescence properties of amorphous silica nanowires by thermal evaporation of silicon monoxide

Large scale synthesis, characterization and photoluminescence properties of amorphous silica nanowires by thermal evaporation of silicon monoxide

Vật lý

... a base pressure of 3.0 Â 10À6 Torr The source SiO and the substrates were inserted in the tube and kept at locations at $1200 1C (center zone) and $1000 1C (in the direction of carrier gas flow), ... in the form of wires having hundreds of micrometers length is clearly seen Fig 2(a) also reveals that several layers of nanowires were deposited one over another and total thickness of the film ... the metal particles, (ii) formation of liquid droplet of metal and Si/SiOx and (iii) the precipitation in the form of solid nanowires after super-saturation of liquid metal–Si/SiOx droplet at...
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Báo cáo Y học: Synthesis, characterization and application of two nucleoside triphosphate analogues, GTPcNH2 and GTPcF pdf

Báo cáo Y học: Synthesis, characterization and application of two nucleoside triphosphate analogues, GTPcNH2 and GTPcF pdf

Báo cáo khoa học

... was tested by formation of the complex between RasGTPcNH2 and the Ras-binding domain of the Ras effector protein c-Raf-1 MATERIALS AND METHODS General description of synthesis High pressure liquid ... methanol and repeated evaporation under reduced pressure, yield of the pure GTPcNH2 was 50–60% One gram of GTP triethylammonium salt was added to a stirred solution of 2.5 mL tributylamine and 1.2 ... identity of the substrate The observed mean half width of, e.g 4.7 Hz for the c-resonance line is typical for a molecule of 523 Da mass at 20 °C in aqueous Fig 31P NMR spectra of GTPcNH2 (A) and GTPcF...
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