... (percentage of CD19 + cells) Results Clinical characteristics of the patientsand response to rituximab therapy The clinicalandlaboratory characteristics of the RA patients who were treated with rituximab ... Teng and colleagues found that only 32% of RA patients had complete depletion of CD19+ cells within the BM as compared with 100% in the PB [4] Leandro and colleagues reported a variable degree of ... in the PB and in the BM of RA patients (d) Representative flow cytometry histograms of HLA-DR expression in PB and BM CD19+-gated cells of a RA patient at baseline and after treatment with rituximab...
... schizophrenics) and 67–75% among outpatients, with 45 and 28% of combination therapies in in- and outpatients being reported, respectively [28-30] The rates of prescription of conventional and atypical ... report [4], with non-FPA patients, no significant differences are observed: benzodiazepines (69% of FPA patients; 69% of non-FPA patients) , atypical (in 51 and 53% ofpatients respectively) and conventional ... at the subjective wellbeing (SWN) scale and number (%) ofpatientswith positive DAI-30 score at admission to and discharge from SPDC, in patients treated with antipsychotics (atypical, conventional...
... loss in RA patients A longitudinal study of the impact of smoking intensity (and cessation) on the body composition ofpatientswith RA may throw more light on the mechanistic basis of these observations ... current and ex-smoker pack-groups However, an ANCOVA model with gender and pack-group as factors and age and weight as covariates (following stepwise elimination of ESR, CRP, DAS28, HAQ score, and ... inception and development of protocol and in the review of the manuscript and served as PhD program supervisor MK provided advice on protocol development and body composition assessments and participated...
... compare the accuracy of the preoperative predictive tests of thoracic echocardiography (TTE) and transesophageal echocardiography (TEE) with the gold standards of surgical findings and pathological ... All patients underwent standard two-dimensional and Doppler echocardiographic examinations with detailed evaluationof heart function Imaging planes were standardized, and they included the parasternal ... mild (n = 25), Table Surgical types of RMCT and relationship between surgical methods and location and degree of RMCT operation methods degree of RMCT# location of RMCT* Anterior Posterior both...
... enrolment A portion of this population was part of the entire cohort of our previous study reporting demographics and prognosis ofpatientswith tetanus [2] The main variables of the study were: ... complications and electrocardiogram (EKG) Evaluationof autonomic profile, catecholamine levels and TNF-α Autonomic instability was characterized by the presence of blood pressure and heart rate ... system function with spectral analyses of heart rate variability in a case of tetanus, recently revealed profoundly decreased activity of both sympathetic and parasympathetic modulation of cardiac...
... 0–31 Quartiles of SAPS II Proning may benefit the most seriously ill subset ofpatientswithacute respiratory distress syndrome Those in the quartile with the highest Simplified Acute Physiology ... Kastani D: Effect of the prone position on patientswith hydrostatic pulmonary edema compared withpatientswithacute respiratory distress syndrome and pulmonary fibrosis Am J Respir Crit Care ... Effect of prone positioning on the survival ofpatientswithacute respiratory failure N Engl J Med 2001, 345:568-573 The ARDS Network: Ventilation with lower tidal volumes as compared with traditional...
... disease), and if there was clinical or microbiological evidence (culture of urine, blood, sputum and ascites) indicative of ongoing infection For the purpose of this study, patientswith hepatorenal ... Systemic and regional hemodynamics in patientswith liver cirrhosis and ascites withand without functional renal failure Gastroenterology 1989, 97:1304-1312 Wiest R, Groszmann RJ: The paradox of nitric ... ± standard error of the mean, and as ∆change ± standard error of the mean The paired t test was used for pairwise comparison within groups, or the Wilcoxon test when appropriate Analysis of variance...
... with or without treatment with beta-blocker at admission in patientswith cardiac aetiology of respiratory failure (adjudicated final diagnosis of heart failure; P = 0.008) andpatientswith non-cardiac ... Diagnosis and Treatment ofAcuteand Chronic Heart Failure 2008 of the European Society of Cardiology Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed ... one-third of ICU patients is multi-causal [15] Accordingly, the aim of the present study was to assess in-hospital and one-year mortality in a cohort of consecutive ICU patientswithacute respiratory...
... discussed with the patients'and their relatives in order to obtain a spirit of understanding The nurses collaborated with the patientsand their families throughout the hospital stay and were ... research [17] The aim of the present study was to evaluate the effectiveness of an ICP in patientswith an acute fracture of the hip The main outcome measure was the length of hospital stay; secondary ... continuity and an accelerated training programme without disturbing the flow ofpatientswith other diagnoses ICP documentation was developed in the form of a check list that displayed what to and when...
... effects of high levels of (S)-albuterol remain unclear [19,22] Most of the pharmacokinetic and pharmacodynamic studies of albuterol have been performed on healthy, mildly asthmatic patients, within ... in acute severe asthma patients, with an up to fivefold difference in concentrations of (R)- and (S)-albuterol [30] The objective of this study was to observe the relationship between (R)- and ... presented to the DEM with an acute exacerbation of asthma The inclusion criteria were adult patients, aged between 18 and 65 years, and self-reported rac-albuterol utilisation within 24 h prior...
... 1:21 http://www.annalsofintensivecare.com/content/1/1/21 Page of Table Baseline characteristics ofpatientswithand without acute kidney injury No acute kidney injury Number Acute kidney injury ... impact of AKI on levels of FGF23 and that was in the setting of rhabdomyolysis [40] We sought to determine the impact of AKI on FGF-23 and parathyroid hormone (PTH) levels in patientswith AKI ... increased risk of death As expected, AKI patients had, on average, higher concentrations of serum phosphorous compared withpatients without AKI In addition, a larger proportion of AKI patients had...
... Santos and Slutsky that this is associated with apoptosis of cells in distal organs (kidney, villi of colon) and end-organ dysfunction (kidney), which potentially underlies the development of MOF ... bronchoalveolar lavage fluid [7], and was associated with a lower incidence of MOF [8] However, the measurement of proinflammatory cytokines does not address the issue of maintenance of alveolar–epithelial ... tissue and bronchoalveolar lavage levels of proinflammatory cytokines, and that stabilization of alveoli is a key issue in reducing atelectrauma The debate on how to best manage patientswith ARDS...
... multicenter survey of off-label use of rFVIIa in American academic hospitals [16], which reported that only 52% of the patients stopped bleeding within hours of rFVIIa administration and 9% suffered ... bleeding, even off-label use demands reasonable expectation of benefit Ongoing bleeding and reasonable expectation of benefit are mandatory even for compassionate off-label use of rFVIIa Competing ... contradicted many initial expectations and demonstrated no clinical benefit of rFVIIa In 2004 RomeroCastro and coworkers [15] reported that all 10 patientswith cirrhosis and bleeding varices stopped bleeding...
... interpretation of data, and critical revision of the manuscript for important intellectual content NGM, AB, and HF participated in analysis and interpretation of data, and critical revision of the Page of ... principles of the Declaration of Helsinki and approved by the local ethics committee Written informed consent was obtained from all participating patientsClinicalevaluationand follow-up Patients ... identification ofpatients at highest risk for adverse outcomes withacute dyspnea remains a challenge Patient history and physical examination remain the cornerstone ofclinicalevaluation [3],...
... episode of ACPE The etiology of hypoventilation as a sign of pump failure is twofold On the one hand, such as among patientswithacute exacerbation of chronic bronchitis, hypercapnia, often acute ... and those with a normal pH (controls) Among patientsof the acidotic group, three subgroups were identified according to PaCO2 and HCO3- values: patientswith respiratory acidosis, patientswith ... according to the type of acidemia on admission A total of 12 patients (10%) with respiratory acidosis, 11 patients (13%) with metabolic acidosis, four patients (6.2%) with mixed acidosis and eight controls...
... NTproBNP and outcome was observed Those patientswith low rates of Copeptin had low rates of death, irrespective of NT-proBNP levels at 30 days In those patientswith an elevation of both, Copeptin and ... consisted of unselected patients presenting to the emergency department of the University Hospital of Basel, Switzerland, with a chief complaint ofacute dyspnea From April 2006 to March 2007, 292 patients ... analysis and interpretation of data and critical revision of the manuscript for important intellectual content NM and AB participated in analysis and interpretation of data and critical revision of...
... and handling the patient samples after HN had departed from CCK and co-ordinating the collaboration with KLK’s laboratory Together with EL she also summarized and processed the patient data and ... al.: Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patientswith metastatic breast carcinoma: a pilot clinical trial Journal of Translational ... after three cycles of Her2-pDNA plus GM-CSF and IL-2 Evaluationof Her2-specific antibody responses Pre- and post-vaccination sera from all patients were analyzed for the presence of anti-Her2 antibodies...
... available and the models should only be used for patientswith similar clinicaland demographic profiles Future work should include validating the model on an independent sample [13], and for patients ... stages of disease Further details of the studies used, the clinical measures, the use of measurements from different time points, and the individual relationship between each of these clinical ... people with quite a wide range of problems in a given domain, corresponding to widely different levels of HRQoL A 5-level version of the EQ-5D has been created and piloted and shows evidence of feasibility...
... that radical resection and type of operation are important prognostic factors In a recent Table 2: Results of multivariate analysis ofclinicalandlaboratory data ofpatientswith colon cancer Source ... http://www.wjso.com/content/6/1/98 ofpatientswith colon cancer, considering survival and pT staging as the independent variables Materials and methods Patients A total of 103 patientswith colon cancer, who ... hepatic flexure ofpatients (8.7%), in splenic flexure ofpatients (7.6%), in descending colon of 10 patients (10.9%) and in sigmoid colon of 34 patients (36,9%) Operative procedure All patients were...
... patientswith PsA by comparison with MRI, x-ray, andclinical findings Materials and methods Patients Fifteen patientswith PsA, with RA, and healthy control persons (CTRLs) were examined with US, ... performed with a ST that was half of the acquired ST Projection radiography X-ray of hands and feet in a posterior-anterior projection was performed within a month of the US X-rays of both hands and ... ultrasonography, x-ray, andclinical examination, with MRI as standard reference method Sensitivities and specificities of US, x-ray, andclinical examination, with MRI as the standard reference method,...