central nervous system cns b cerebrospinal fluid spaces of the brain
Báo cáo y học: "Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection" ppt
... neopterin is biosynthesised at the expense of 5,6,7,8-tetrahydrobiopterin (BH4), the necessary cofactor of amino acid monoxygenases [30,31] BH4 is also cofactor of the cytokine-inducible enzyme nitric ... concentrations and the loss of brain tissue expressed as the ventricle -brain ratio measured by computed tomography [32] The parallel production of systemic and CNS < /b> neopterin and ROS pro- Page of 12 duction ... morbidity and mortality of HIV infection, including those involving the CNS < /b> and the previously most common of these, ADC/HIVE The study of CSF neopterin has contributed to our understanding of CNS...
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Báo cáo y học: "Macrophage migration inhibitory factor in cerebrospinal fluid from patients with central nervous system infection" potx
... ampicillin If bacteria were demonstrated in the CSF and/or blood, then antibiotic therapy was changed in based on the susceptibility profile of the pathogen The duration of antibiotic therapy was ... concentration of μg/ml After the plates were washed three times with wash buffer (PBS with Triton X-100), the unbound sites were blocked by adding 300 μl blocking buffer (PBS with 1% bovine serum albumin ... N, Cowland JB: Granules of the human neutrophilic polymorphonuclear leukocyte Blood 1997, 89:3503-3521 Hagberg L: The clinical use of cerebrospinal fluid neopterin in central < /b> nervous < /b> system < /b> infections...
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Cancer of the Brain and Other Central Nervous System doc
... 25.1: Cancer of the Brain & Other Central < /b> Nervous < /b> System:< /b> Number of Cases and Exclusions, 12 SEER Areas, 1988-2001 Brain Other CNS < /b> Number Selected/ Remaining Number Excluded Number Selected/ ... lesion of brain Brain, NOS * National Cancer Institute NOS, Not Otherwise Specified 210 SEER Survival Monograph Chapter 25 Cancer of the Brain and Nervous < /b> System < /b> Table 25.7: Cancer of the Other Central < /b> ... patients with other CNS < /b> cancer, the spine was the most common primary site (53.9% of total), followed by the brain (41.3% of total) and other (4.8% of total) Other CNS < /b> cancers in the brain (malignant...
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Báo cáo khoa học: Planarian peptidylglycine-hydroxylating monooxygenase, a neuropeptide processing enzyme, colocalizes with cytochrome b561 along the central nervous system pptx
... observable in the cell body of neurons in the peripheral region of the brain Cytochrome b5 61 was observable in neuropil (np), composed of axons and dendrites of the neurons, as well as in their ... acquired the neuroendocrine vesicles equivalent to those seen in the present-day neurons of higher animals by the time of the emergence of the Plathelminthes in the evolutionary history The eye of the ... origin of the vertebrate CNS < /b> by being the simplest and most remote animal to exhibit these vertebrate features [54] Agata and coworkers described in detail the structure of the CNS < /b> of the freshwater...
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báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx
... that the lack of CCR5 does not protect from MS, but rather it may predispose to the chronic course of the disease [69] This would further imply that in view of the redundancy in the chemokine system,< /b> ... state of inflammatory activity and demyelination, as previously described by Brück et al [36] amoeboid form of the GSA /B4 + cells, indicating that these chemokine receptors are expressed by cells of ... with the avidin biotin peroxidase (ABC) detection system < /b> (ABC Elite, Vector Laboratories) and diaminobenzidine as chromogen Finally, a biotinylated lectin (GSA /B4 , Vector Laboratories) combined...
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Section III - Drugs Acting on the Central Nervous System docx
... ensembles to regulate the flow of information within and between the regions of the brain Cellular Organization of the Brain Present understanding of the cellular organization of the CNS < /b> can be ... anatomically, the blood brain barrier is an important boundary between the periphery and the CNS < /b> in the form of a permeability barrier to the passive diffusion of substances from the bloodstream ... occur in either direction across the barriers The diffusional barriers retard the movement of substances from brain to blood as well as from blood to brain The brain clears metabolites of transmitters...
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Báo cáo sinh học: "The long term effects of chemotherapy on the central nervous system" docx
... certain brain tumors, especially for the very young Because of the rapid myelinization that occurs in infants, the finding by Noble and colleagues [1] of the adverse effects of chemotherapy on ... injected either intrathecally (into the cerebrospinal fluid) or intravenously and intrathecally) This study and many Journal of Biology 2006, 5:21 http://jbiol.com/content/5/7/21 Journal of Biology ... in the absence of radiation The best data on the cognitive effects of chemotherapy alone have come from studies of children with leukemia who did not have CNS < /b> leukemia Unlike children with brain...
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Báo cáo sinh học: "Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system" doc
... nuclei; the distribution, morphology and size of these nuclei resembled those of the microvasculature endothelial cells of the CNS < /b> (Figure 11c-e) Double-labeling to visualize expression of Journal of ... also raise the question of whether multiple pathological changes contribute to the effects of chemotherapy on cognition The ability of irradiation to the CNS < /b> to suppress the generation of new neurons ... taken from the DG showing double-labeling of the vascular endothelial cell marker PECAM (CD31) with TUNEL+ nuclei In the subset of animals in which evidence of endothelial cell death was observed,...
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Báo cáo sinh học: "How chemotherapy damages the central nervous system Christina A Meyers" ppsx
... injection They found a more persistent suppression of proliferation in regions of the brain where proliferation is essential to normal function (the subventricular zone, the dentate gyrus of the hippocampus ... whereas they found enhanced long-term potentiation in slices obtained and 53 weeks after treatment [11] Thus, some of the variability of the results in these studies may be related to the time ... response in the mice at various times following treatment Loss of myelin is known to increase the latency between specific peaks in the auditory brainstem response, reflecting slowing of the impulse...
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Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx
... of nNOS and iNOS in the nonneurological control brain Both nNOS and iNOS immunoreactivity was recognized in the brain of control goats No inflammatory cells were found in the brain sections of ... Harrisburg, Pennsylvania In all the selected midbrains, L monocytogenes was confirmed by immunohistochemistry using the antisera described below Neither direct culture of bacteria nor cold enrichment ... rabbit antiglial fibrillary acidic protein (GFAP) (Sigma, St Louis, MO), rabbit anti-iNOS (Sigma), rabbit anti-nNOS (Sigma) Immunoperoxidase staining was done using the labeled [strept]avidin-biotin...
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báo cáo khoa học: "Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature" pdf
... occlusion of the cerebral Page of vessels, brain biopsy should be performed [15] However, the classic appearance of alternating narrowing and dilatation is not completely specific and has been observed ... Prognosis of patients with suspected primary CNS < /b> angiitis and negative brain biopsy Neurology 2003, 61:831-833 23 Fountain NB, Lopes MB: Control of primary angiitis of the CNS < /b> associated with cerebral ... draft WY drew the pictures WZ revised the draft SL described the MRI features GL provided the pathological diagnosis TJ was the surgeon and gave the final approval of the version to be published Competing...
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Báo cáo khoa học: " Experimental concepts for toxicity prevention and tissue restoration after central nervous system irradiation" ppt
... selective for endothelium [50] The compound reduced the development of peritumoral edema and of radiation-induced vascular changes in the parts of the brain which were within the region of the steep ... experimental CNS < /b> damage models suggest that IGF-1 causes an increase in oligodendrocyte numbers in previously damaged areas of the rat spinal cord [69] IGF-1 reduces the permeability of the blood -brain barrier ... permeability and leukocyte adhesion in the rat blood -brain barrier: modulation with anti-ICAM-1 antibodies Brain Res 2003, 969:59-69 Daigle JL, Hong JH, Chiang CS, McBride WH: The role of tumor...
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Báo cáo y học: "The impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI" ppsx
... in the case of the former, but much higher in the case of the latter Analysis of the IQ scores in our control group suggests the presence of a practice effect Out of 132 controls tested at the ... observation of a difference in mean IQ between patients and controls Overall these data suggest that factors other than the mode of CNS < /b> directed treatment determine the likelihood of CNS < /b> morbidity ... comparable intervals for their controls Some flexibility was allowed around the ideal test date: Within the first year for the month test, and year either side of both the 3- and 5-year test dates The...
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Báo cáo y học: " Primary central nervous system lymphoma presenting as a pure third ventricular lesion: a case report" pps
... supra-tentorially, in the white matter of the frontal or parietal lobes or in the sub-ependymal regions However, lesions may also appear in the deep gray matter [3] Typically, these lesions are in the central < /b> ... consent was obtained from the patient for publication of this case report and any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal ... Primary central < /b> nervous < /b> system < /b> lymphoma: radiologic-pathologic correlation RadioGraphics 17, 1497–1526 (1997) DE Hobson, BA Anderson, I Carr, M West, Primary lymphoma of the central < /b> nervous < /b> system:< /b> ...
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báo cáo khoa học: "In vivo observation of gold nanoparticles in the central nervous system of Blaberus discoidalis" potx
... and the brain extracted The brain was rinsed with DPBS and fixed with FrozFix (Newcommer Supply) for two hours to allow thorough diffusion of the fixative in the brain tissue The brain was then ... the location of the intensity profile below These locations were selected because they exhibit the highest intensity The fluorescence of the treated brain was significantly higher than that of ... at a power of 350 W and a base pressure of 10-10 Torr The XPS system < /b> was used to verify the presence of the nanoparticles inside the brain by scanning the cryocut and fixed cockroach brain slices...
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Báo cáo y học: "Possible gabapentin and ketamine interaction causing prolonged central nervous system depression during post-operative recovery following cervical laminoplasty: a case report" potx
... was obtained from the patient for publication of this case report and any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this Journal Page of ... selected because of our patient’s history of asthma and to reduce his post-operative pain medication requirement To examine the interaction of these drugs, one must further investigate the bioavailability ... fat, liver, lung and brain Peripheral fat distribution, along with redistribution from the CNS < /b> to slower equilibrating peripheral tissues, suggests that ketamine is bioavailable beyond its initial...
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báo cáo khoa học: "Extensive central nervous system involvement in Merkel cell carcinoma: a case report and review of the literature" docx
... on the number of metastases, systemic spread of the disease and the accessibility to surgery We believe that the CNS < /b> metastases of MCC are an expression of a hematogenous systemic spread of the ... et al [7] Table shows the heterogeneity of treatment of MCC brain metastases because there is no evidence-based first choice of treatment described in the literature for this type of brain metastasis ... metastasis We believe that until a considerable amount of case reports are available in the literature, the choice of treatment of MCC brain metastases will depend, as in many other types of brain metastases,...
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Báo cáo khoa học: "Central nervous system Toll-like receptor expression in response to Theiler''''s murine encephalomyelitis virus-induced demyelination disease in resistant and susceptible mouse strains" ppsx
... central < /b> in the enhanced response by the susceptible mice is the intensity of the TLR signal By having a higher number of TLRs on the surface and inside the endosomes and lysosomes of the immune ... elements in the central < /b> nervous < /b> system < /b> of SJL/J and C57BL/6 mice after infection Expression Expression of Toll-like receptors for bacterial elements in the central < /b> nervous < /b> system < /b> of SJL/J and C57BL/6 ... vitro induction by TMEV in cultured microglia[4] The use of our in vivo approach permits us to observe the co-localization of the TLR expression to the specific areas of the CNS < /b> where the TMEV was...
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Báo cáo y học: "Ischemia as a possible effect of increased intraabdominal pressure on central nervous system cytokines, lactate and perfusion pressures" ppsx
... partially by decreased absorption of the cerebrospinal fluid (CSF) in the region of the lumbar cistern and the dural sleeves of the spinal nerve roots He suggested that this finding correlates with the ... lactate in the CSF suggested the development of CNS < /b> ischemia Abbreviations ACS: abdominal compartment syndrome; CNS:< /b> central < /b> nervous < /b> system;< /b> CVP: central < /b> venous pressure; CPP: cerebral perfusion ... However, we observed that baseline IAP was increased at the beginning (9.9 mmHg) and at the end of the experiment (11.4 mmHg) An explanation of this is provided by the mechanism of action of fentanyl,...
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Báo cáo y học: "Invasive pulmonary and central nervous system aspergillosis following slops aspiration in a trauma patient" pot
... in both the lung and the brain White arrows, progression of encephalomalacia in the left frontal lobe Lin SJ, Schranz J, Teutsch SM: Aspergillosis case-fatality rate: systematic review of the ... Denning DW, Herbrecht R, Kontoyiannis DP, Marr KA, Morrison VA, Segal BH, Steinbach WJ, Stevens DA, van Burik JA, Wingard JR, Patterson TF; Infectious Diseases Society of America: Treatment of aspergillosis: ... practice guidelines of the Infectious Diseases Society of America Clin Infect Dis 2008, 46:327-360 Park DW, Sohn JW, Cheong HJ, Kim WJ, Kim MJ, Kim JH, Shin C: Combination therapy of disseminated...
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