... percent ofthe IMRT Group had grade or hearing loss, compared to 64% ofthe conventional-RT group The sparing ofthe hearing apparatus is of special importance since several modern combined chemotherapy ... helical tomotherapy have the potential of selectively sparing the thyroid gland and breast tissue in craniospinal irradiation The number of children treated with IMRT andthe hard evidence for the benefit ... treatmentofthe children HB is responsible for the anaesthesia management ofthe children PH is responsible for the clinical treatmentofthe children as head ofthe division of radiation oncology in...
... (75.3%) Introduction The employment of preoperative radiotherapy (RT) combined or not with chemotherapy (CT) has been used inthetreatmentof rectal cancer for the past two decades and its employ ... according to the actuarial method of Kaplan and Meier [24] The calculation of OS, DFS and LC was performed from the date of diagnosis to the date ofthe event Survival was measured from the date of ... sphincter-sparing surgery is nowadays the main subject of controversy One ofthe most important controversies is whether the degree of downstaging warrants this type of surgery [1] Results of the...
... cystic carcinomas ofthe head and neck are a unique kind of tumour deriving from cells ofthe major and minor salivary glands, they account for 25% of all malignant salivary gland tumours in different ... by slice on thetreatment planning CTs using the 3D-conformal radiotherapy planning system VIRTUOS which was developed at the dkfz An image fusion ofthetreatment planning CT andthe MRI scan ... material wrapped around the head ofthe patient Serial mm CT slices oftheofthe whole treatment area plus a superior margin of cm and an adequate inferior margin to cover the neck lymph nodes...
... to examine the uncertainty inthe model andthe stability ofthe results The first PSA allowed the input values for adherence rates, relapse rates, treatment discontinuation rates, andthe generic ... $38 [71] These results remain robust despite the fact that they are assumed to occur inthe first quarter oftreatment initiation, rather than weighing the increase inthe rates over the quarterly ... created by setting the minima and maxima ofthe range to be 50% and +50% ofthe base case value The second PSA extended the first analysis by adding distributions around the number and cost of resources...
... 2004, of portacaval shunting, thereby decreasing first pass metabolism; decrease in quantities and affinity of plasma proteins, thereby increasing free-drug levels; increase in volume of distribution ... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of ... pre-dialysis and 2–3 hrs following the post-dialysis dose There is a case report in which lithium levels were maintained inthe therapeutic range by intraperitoneal administration of lithium during continuous...
... provide written informed consent Use ofother natural health products, including glucosamine and chondroitin, one month prior to study and during the study, other than multivitamin and mineral supplements ... acetaminophen or ibuprofen within days of randomization Subject is unwilling to stop taking pain medication other than the study medication (for arthritis or other types of pain) or is unwilling ... unwilling to stop taking other medications for thetreatmentof OA Any other condition that, inthe opinion ofthe investigator, would adversely affect the subject's ability to complete the study or...
... tissue and gastrointestinal tract, as well as other sites, are known to reach the CNS to effect changes in feeding behavior and energy expenditure Thus, insulin, leptin and ghrelin, as well as other ... closely and rapidly with reciprocal changes inthe levels ofthe orexigenic and anorectic Signaling mediators inthetreatmentof obesity neuropeptide expression inthe hypothalamus [22] Thus an increase ... explored further Other areas ofthe brain have also been shown to regulate feeding via AMPK [35,36] Of interest is the extensive use of fructose as a sweetener inthe human diet [37] Glucose and fructose...
... at each phase ofthe cell cycle by various complexes of cell-cycle-related molecules, including cyclins, cyclin-dependent kinases, their inhibitors andthe retinoblastoma protein (RB), as well ... calorie intake induces expression of RMI1 and E2Fs in adipocytes, and these changes in expression are expected to increase a positive interaction between the molecules The increased expression of ... recruitment of preadipocytes [12], suggesting that these cyclin-dependent kinase inhibitors are important inthe regulation of adipocyte number The S-phase kinase-associated protein (Skp)1–CullinF-box...
... products ofthe manufacturing industry in Thailand This will result in an increase inthe output ofthe manufacturing industry in Thailand, which could result in an increase in demand for relevant inputs ... Only half ofthe 14 industries in Thailand and industries in Vietnam had values for backward linkages greater than one in 2000 Inthe case of forward linkages, industries in Thailand andin Vietnam ... outside the country, say, Vietnam This new demand for the output ofthe suppliers in Vietnam will create an increase in their output and, directly and indirectly, the output ofother industries in...
... screening including erythrocyte sedimenta- Page of tion rate and C-reactive protein was normal Plain radiographs revealed areas of periprosthetic osteolysis inthe femur andthe tibia, and a ... image ofthe left knee showing the introducing cannula and simultaneous venting ofthe medial tibial condylar cyst Discussion When dealing with massive periprosthetic osteolysis the aims of surgery ... years later In January 2005 the patient began to develop similar medial pain and swelling inthe left knee A bone scan showed increased activity inthe medial femoral condyle indicating possible...
... Annals of General Psychiatry 2009, 8:16 thetreatmentof acute mania, the approval of quetiapine andthe olanzapine-fluoxetine combination against acute bipolar depression andthe approval of olanzapine, ... in all subpopulations irrespective ofthe baseline MADRS score andthe presence of rapid cycling, with the exception of remission in patients over 55 years of age [107] Another metaanalysis of ... which included 66 ofthe 67 patients who completed the 26-week period Unfortunately only 12 of them (5 inthe placebo group andinthe aripiprazole group) completed the 74-week treatment period The...
... effective inthetreatmentof psychotic major depression, andthe switch to sertraline worsened the psychotic symptoms inthe patient The mechanisms underlying the opposite effects of these two ... fluvoxamine binds to sigma-1 receptors inthe intact human brain at therapeutic doses [25], suggesting that sigma-1 receptors are involved inthe active mechanisms of fluvoxamine [19] Interestingly, ... that activation ofthe dopaminergic system by the inhibition of dopamine transporter may be involved inthe mechanism of unwanted effects (deterioration of psychosis) of sertarline in this case,...
... radiation in their history Other studies haven’t shown any positive effects of radiotherapy on patients outcome[30-32], while the recent literature indicates the beneficial role ofthe radiotherapy in ... concerning radiotherapy and followed up the patient at his out-patient clinic AK was the radiologist performing the preoperative and postoperative CT and MRI scans and wrote the part ofthe paper ... contributions All ofthe authors have been involved in drafting this paper and have read and approved the final manuscript KG conceived the idea ofthe paper, reported the case, performed the literature...
... HT at the Tomotherapy Unit ofthe Grupo IMO inthe context of multidisciplinary national and international treatment protocols All the patients were treated with curative intent, including those ... to the Tomotherapy treatment planning system (Tomotherapy Inc., Madison, WI) to perform inverse treatment planning The planning goal was to deliver the prescription dose to at least 95% ofthe ... tomotherapy as a new treatment technique for whole abdominal irradiation Strahlenther Onkol 2008, 184:145-9 Vlachaki MT, Kumar S: Helical tomotherapy inthe radiotherapy treatmentof Hodgkin’s...
... medications for thetreatmentof withdrawal syndromes inthe initial stage of stopping the chronic use of an addictive substance (including alcohol and opiods), [70] medication to reduce the risk of relapse ... associated with the successful dissemination of innovations into clinical practice These factors were subsequently highlighted inthe Institute of Medicine’s report ‘Improving the Quality of Health ... advocate-involvement Thus, we hypothesize that EBTs are of lower priority for these substance abuse programs given these other challenges they face in maintaining the services they currently Page of...
... stages III and IV) Combining the studies, there were 439 patients, and over 98% of these were late-stage Treatment efficacy The main characteristics ofthe four studies are shown in table 3, ... frontline chemotherapeutic agents, included the R-CHOP study of Hiddemann et al [5] andthe R-CVP study of Marcus et al [7] Both of these provided adequate patient data; the comparison is shown in ... of those met all inclusion criteria as studies of frontline or re -treatment Two of those four met the criteria for the first analysis (frontline treatment alone) Outcome The primary goal of the...
... component ofthe burden of illness and its economic cost [5,6] The financial cost of schizophrenia inthe United States in 2002 was estimated to be $62.7 billion [6] In another study ofthe economic ... comparison of baseline-to-endpoint change in productivity level in olanzapine-treated versus other- treated chronically ill patients with schizophrenia Comparison between olanzapine and each oftheother ... Ascher-Svanum H: Meta-analysis oftreatment discontinuation for any cause comparing olanzapine andother antipsychotics inthetreatmentof schizophrenia 15th Biennial Winter Workshop in Psychoses:15-18...
... we assessed the proportion of patients receiving the service, the rate of use and rate of admissions, the time to first use ofthe service, andthe annual health care cost, in terms of total health ... antipsychotic within 14 days of discontinuation ofthe initial therapy Data on the occurrence of acute-care service use, the time to the use of such services, and total-care and acute-care service ... hospitalization/day treatment, crisis services, and any acute-care services; as well as the total duration (in days) of each of these services andthe rate of admissions to the facilities providing them Total and...
... participated inthe design ofthe study andthe analytical plan DEF participated inthe design ofthe study, the analytical plan, the interpretation ofthe results, and assisted in drafting the manuscript ... manuscript DS and ES participated inthe design ofthe study, the analytical plan, the interpretation ofthe results, and assisted in drafting the manuscript They were also involved in preparing the resource ... costing data of US-SCAP XP performed the expanded statistical analyses, participated inthe design ofthe study, the analytical plan, andthe interpretation ofthe results RRC assisted with the interpretation...
... contributions SG was involved inthe conceptual design of this study, inthe clinical management ofthe patient, andinthe writing and editing ofthe manuscript VA was involved inthe Page of (page number ... scan examinations VDF was involved inthe clinical management and contributed to the writing and editing ofthe manuscript GM supervised the entire treatment, provided financial and administrative ... obtained from the patient at the beginning of each treatment A separate institutional informed consent was obtained at the first visit, with regard to thetreatmentof personal data and use in...