... examination of the structureandfunctionof computer hard drives and DNA Theoretical Biology and Medical Modelling 2010 7:3 Submit your next manuscript to BioMed Central and take full advantage of: ... DD conceived of the initial concept for comparative analysis between the DHD and CHD andand drafted the initial version of the manuscript GA drafted portions of the manuscript and revised it ... correlations and expansions to these properties by structural and informational aspects of the of DHD, 3) examination of the current discrepancies between the CHD and the DHD, and how these discrepancies...
... concentrations is the result of fluorophore uptake and transport kinetics, determined by the physical and chemical properties of the fluorophore, and passive and active transmembrane transport kinetics in ... expression of leucophores and melanophores, and minimal expression of xanthophores and iridophores, STII medaka are essentially transparent throughout their life cycle In embryo, larval and juvenile ... rodent, avian, primate, human) are applied to understanding the mechanisms and modes of actions involved in xenobiotic induced injury, a betterment of our comparative understanding, and ability...
... ARF2 human ARF3 human ARF3 human ARF4 human ARF4 human ARF5 human ARF5 human ARF6 human ARF6 rat Arl1 rat Arl1 human Arl5 human Arl5 human Arl8 human Arl8 human Arl4 human Arl4 human Arl7 human Arl7 ... ARFs, and Arl1), endosomes (ARF1 and ARF6), plasma membrane (ARF1, ARF6 and ARFRP1) including focal adhesions (ARF1) and membrane ruffles (ARF1 and ARF6) (Schurmann et al., 1995; Moss and Vaughan, ... (Class I, II and III ARFs and Arl1) and signaling (Class I, II and III ARFs) (Schurmann et al., 1995; Moss and Vaughan, 1998; Huang et al., 1999; Chavrier and Goud, 1999; Randazzo et al., 2000; Takai...
... Biotics and abiotics Energy and material flow Human impacts, consequences and solutions Conclusion LOCATION Thong Nhat Park Peninsula : 1200 m2 Including : mainland, lake, plants, animals ... Increasing the number of wastebasket Planning the rubbish dumps and quick transporting the waste as soon as possible More rules (including penalties) for the restaurant and visitors to keep ... keep the park green, clean and beautiful CONCLUSIONS Plant species on peninsula are quite diverse People are having huge impacts on the formation and development of the ecosystem Awareness...
... advances have been accompanied by a relative decrease in the number of studies aimed at gaining an understanding of the structural conformation of chromatin, and the changes in chromatin structure ... H3, meaning that it can direct recruitment of HBO1 both in advance ofand in the wake of a transcribing polymerase The other most likely candidates driving histone acetylation during transcription ... co-localization of many active promoters and enhancers at one site is an efficient way of sustaining active transcription by maintaining threshold levels of polymerases and transcription factors...
... immunocytochemistry and lgÆmL)1 for coimmunoprecipitation Materials and methods Animals Primary cultures, transfection and imaging of hippocampal and cerebellar neurons Hippocampal and cerebellar ... stability and rearrangement of microtubules in neuronal dendrites [13–15] and is associated with some neurological and psychiatric disorders [16,17] However, the structurefunction relationship of ... patterns To quantify dendrite growth and branching, 15 neurons transfected with each construct were randomly chosen for each experiment, and EGFP fluorescent images of their dendrites were analyzed...
... of many kinds of consumers The above framework can be applied to understand quantitatively how Lindeman efficiencies, rates of energy and material flow, biomasses and abundances vary within and ... extension, showing that plant density across the spectrum of plant sizes from algae to trees and across a range of ecosystem types from oceans, freshwaters, wetlands, grasslands and forests shows the ... ECOLOGY predictions about the effects of energy and materials on the ecology of organisms and the roles of organisms on the fluxes and storage of energy and materials in ecological systems The...
... roles of plant APs References Davies, D.R (1990) The structureandfunctionof the aspartic proteinases Annu Rev Biophys Biophys Chem 19, 189–215 Dunn, B.M (2002) Structureand mechanism of the ... different isoforms by the excision of the prosegment andof most of the PSI [21] Conversely to what has been found in vivo [31], heavy and light chains of the processed forms of recombinant cyprosin ... mechanisms of degradation of pathogenesis-related proteins in plants Plant Physiol 95, 616–622 Guevara, M.G., Oliva, C.R., Machinandiarena, M & Daleo, G.R (1999) Purification and properties of an...
... consisting of the extracellular ligand-binding domain of the a6 subunit and the transmembrane and intracellular domains of the a3 subunit was used in this study PIA selectively blocks rat and human nAChRs ... current and confirmed the contribution of a7* receptors to synaptic transmission A recent study based on single channel recordings and the use of a-conotoxins MII and AuIB further dissected and correlated ... cells and assumed to Betz for his support and for critical reading of the manuscript be selective for a3b2 and a3b4 interfaces and unable to inhibit an a-BTX-sensitive current attributed to an a7*...
... [45] An unusual property of left-handed helices is that most extended polypeptides with L-amino acids have an inherent right-handed twist [46] The lefthanded b-helices have b-strands with left-handed ... other and with proteins that have a similar fold Structureof sbwAFP and TmAFP The structureof sbwAFP has been determined by X-ray ˚ crystallography to 2.5 A and by NMR at both 30 °C and °C ... [31,32,36] and their threedimensional structures were determined [34,37–40] In subsequent sections, we describe the structureand dynamics of each protein, and present a comparison of sbwAFP and TmAFP...
... correct and standardised principles of management; and that only with standardised principles of management can results in various series and in various countries be compared to best advantage and ... form and influence its extent and activity The extent and activity of the lesions vary directly with three of the fundamental factors of pathogenesis, quantity of bacilli, virulence of bacilli, and ... depending on the relative potency of the infecting dose on the one hand and the degree and rapidity of development of acquired resistance on the other The dose of bacilli implanted by inhalation is usually...
... antiparallel strands (1, and 7) and strand 6, which is parallel to strand b-Strands are located between the four a-helices (a1, 278–294; a2, 305–313; a4, 374–381; and a5, 397–405), with two of ... variation of pH in the range between 6.3 and 7.7, of ionic strength between 25 and 2616 100 mm NaCl andof temperature between 278 and 313 K did not lead to any detectable change in the populations of ... structure calculation for the open and closed conformers of the C-terminal domain of human eRF1 Fig S3 NOE map of the minidomain (residues 329– 372) of human eRF1 NMR structureandfunction of...
... identification and distribution of TLP genes in nature, the structural and functional characterization of the TLP from various organisms, and the evolution of TLP and transthyretin The identification of TLPs ... portions of strands B and C that protrude towards the solvent and in the conformation of the long loop connecting strands D and E [17] Greater differences are observed between the structures of B ... conformation observed in b-strands A, G and H [17] Structural nature of the TLP and transthyretin active sites One of the striking features of transthyretin is the central channel of the protein into which...
... in which the b1-strand and b2-strand are adjacent and parallel to each other, and the b¢-strand is adjacent and antiparallel to the b1-strand (Fig 1) The length and sequence of the variable loop ... composed of three antiparallel b-strands is abutted by three a-helices (a1, a2, and a¢) The b-sheet in type I KH domains consists of three b-strands in the order b1, b¢ and b2 The b1-strand and b2-strand ... Valverde et al Structureandfunctionof KH domains A B C Fig 10 Crystal structureof tandem type II KH domains of NusA in complex with RNA The tandem KH1–KH2 domains of NusA recognize RNA ligand 5¢-GAACUCAAUAG...
... Scotland His son and heir held great fiefs in England,[38] and he granted tracts of land to Anglo-Norman nobles A Bruce and a Balliol, who each held possessions both in Scotland and in England, ... III AND SCOTLAND, 1328-1399 64 " VI SCOTLAND, LANCASTER, AND YORK, 1400-1500 80 " VII THE BEGINNINGS OF THE ENGLISH ALLIANCE, 1500-1542 101 AnOutlineof the Relations between England and Scotland ... plains, that soften'd vale, Were once the birthright of the Gael; The stranger came with iron hand, And from our fathers reft the land." AnOutlineof the Relations between England and Scotland (500-1707)...
... activity and substrate binding in glucokinase and GlcNAc kinase [28] It can therefore be concluded that these cysteines have an important and identical role in the enzymatic mechanism of both ... a-helices and the b-sheets Three-dimensional modelling was performed using the RASMOL software PSI-BLAST RESULTS Construction of cysteine mutants and functional expression in E coli BL21 In an earlier ... III, a-helix (B) Top view of the threedimensional structureof GlcNAc kinase The relative positions of cysteines are labeled with a star Ó FEBS 2002 Structureandfunctionof GlcNAc kinase (Eur...
... course of inactivation of wild-type GST I and mutant Phe51Ala by SDTG Wild-type (r) and mutant Phe51Ala (j) were incubated in the presence of 72.7 and 92 lM SDTG, respectively, at pH 6.5 and 25 ... buffer, pH 7.0, and its UV spectra were recorded between 250 and 190 nm Molecular modelling Structure manipulations and analysis were performed using the PYMOL software [41] Results and Discussion ... activity of the partial active enzyme intermediate, and kfast and kslow are Affinity labelling of maize GST I (Eur J Biochem 271) 3505 the rate constants for the slow and fast phase of the reaction Analysis...
... characterized the effects of yet another cyanine dye, 3,3¢-dipropyl-2,2¢-thiadicarbocyanine iodide [DiS-C3(5); Fig 1], on mitochondrial structureandfunction Materials and methods Analysis of mitochondrial ... Ministry of Education, Science, and Culture of Japan, and a fellowship from Katayama Chemical Industries, Co., Ltd (Osaka) to T.Y Ó FEBS 2004 Effects of DiS-C on mitochondrial structureandfunction ... appearances of mitochondria (A) and (B) show the appearance of mitochondria treated with 10 lM Ca2+ and with both lM DiS-C3(5) and 10 lM Ca2+, respectively Bar under (B) indicates lm for all panels...
... monodon hemocyanin structureandfunction equilibrium constant, lo, describes the ratio of conformations r and t in the absence of ligand: lo ¼ ½t0 ½r0 Three-state MWC model An extension of the ... monodon hemocyanin structureandfunction Table Multiple alignment of crustacean hemocyanin (Hc) sequences The subunits followed by the abbreviations used in table and by the SwissProt and NCBI accession ... of dodecameric and hexameric Penaeus monodon hemocyanin (Hc) (data from Fig 9, pH 8.0 and pH 7.5) with the oxygen partial pressures of pre- and postbranchial hemolymph, expected in the case of...
... Boschi-Muller, M Antoine, A Gand and G Branlant Laboratoire MAEM UMR 7567 CNRS-UHP, Universite´ Henri Poincare´ Nancy I, vandoeuvre-le`s-Nancy, France E-mail: Sandrine.Boschi@maem.uhp-nancy.fr Methionine ... derivatives of arginine (HMA) synthes´ ized by Trezl and co-workers from CH2O and L-arginine may belong to that type of molecules HMA was found in human blood and urine, and in plants (leaves, fruits and ... MCF-12A were used The expression of PDGF-R and c-Kit, their ligands, MMP-9 and signal transduction pathways PI3/Akt and MAPK were studied by RT-PCT and western blotting and immunocytochemistry The...