altered microrna expression in human heart disease
báo cáo khoa học: " High-throughput sequencing identifies STAT3 as the DNA-associated factor for p53-NF-κB-complex-dependent gene expression in human heart failure" pps
... domain. Purified recombinant GST-RELA peptides (amino terminus, DNA binding domain; carboxyl terminus, transactivation domain; in the left panel, the arrow indicates the GST-RELA 428-551 amino ... multi-protein complexmay control gene expression program in heart failure.Understanding the way that different DNA binding pro-teins interact with DNA regulatory elements and modu-late gene expression ... mir-21 expression. p53 behaves as a co-factor in this complex because despite a mutation in its DNA binding domain, mutant p53 was still capable of binding RELA and the cis-element, and inducing...
- 14
- 244
- 0
Báo cáo sinh học: "Differentiation associated regulation of microRNA expression in vivo in human CD8+ T cell subsets" doc
... implication of microRNAs in CD8+T cell differentiation in humans, microRNA expression profiles were analysed using microarrays and quantitative PCR in several human CD8+T cellsubsets defining the ... *53 hsa-miR-30d MicroRNA ranking according to relative expression in CD8+T cells. Groups Aand B are as identified by unsupervised clustering in Figure 1b. *: microRNA belonging to the miR-17~92 ... fewhighly expressed microRNAs prevailed in frequency.Interestingly, these microRNAs include miR16, miR-21,miR-142-3p and miR-142-5p, wh ich were also found in the group A in human CD8+T lymphocytes,...
- 8
- 399
- 0
báo cáo hóa học:" Differentiation associated regulation of microRNA expression in vivo in human CD8+ T cell subsets" pptx
... implication of microRNAs in CD8+T cell differentiation in humans, microRNA expression profiles were analysed using microarrays and quantitative PCR in several human CD8+T cellsubsets defining the ... *53 hsa-miR-30d MicroRNA ranking according to relative expression in CD8+T cells. Groups Aand B are as identified by unsupervised clustering in Figure 1b. *: microRNA belonging to the miR-17~92 ... fewhighly expressed microRNAs prevailed in frequency.Interestingly, these microRNAs include miR16, miR-21,miR-142-3p and miR-142-5p, wh ich were also found in the group A in human CD8+T lymphocytes,...
- 8
- 326
- 0
Báo cáo khoa học: Fast set-up of doxycycline-inducible protein expression in human cell lines with a single plasmid based on Epstein– Barr virus replication and the simple tetracycline repressor ppt
... doxycycline-inducible protein expression by just a single transfec-tion. pEBTetD contains an Epstein–Barr virus origin of replication forstable and efficient episomal propagation in human cell lines, ... lines.Several widely used systems for regulated expression in mammalian cell lines are based on the tetracyclineKeywordsdoxycycline; EpsteinBarr virus;polyadenylation; regulated protein expression; ... inducible protein expression M. Bach et al.788 FEBS Journal 274 (2007) 783790 ê 2007 The Authors Journal compilation ê 2007 FEBS Fast set-up of doxycycline-inducible protein expression in human...
- 8
- 331
- 0
Báo cáo khóa học: Ouabain stimulates endothelin release and expression in human endothelial cells without inhibiting the sodium pump Robert Saunders and Georgios Scheiner-Bobis pptx
... but also in identifying several of them as ouabain orits isomer [3–6] or as its congeners, such as digoxin [7,8],proscillaridin A [9], 19-norbufalin [10] and marinobufagenin[11]. In addition, ... 2; Worthing-ton) in Pucks saline solution (Seromed, Berlin, Germany)containing 20 mMHepes, and incubated at 37 °Cfor20 min to detach the endothelium. The cells were washedout using 20–50 ... well.86Rb+uptake was also investigated after preincubatingthe cells for 15 min with 1 lMprotein kinase C inhibitorRo-31-8425, 5 lMNa+-channel inhibitor tetrodotoxin,500 lMmitochondrial...
- 9
- 288
- 0
Báo cáo hóa học: " Altered gene expression in asymptomatic SHIV-infected rhesus macaques (Macacca mulatta)" pdf
... actin-binding genes appeared in thelist; namely: anillin (ANLN, ID: R16712), destrin (DSTN,ID: AA424824), utrophin (UTRN, ID: AA676840), cyclin-dependent kinase 2-interacting protein (CINP, ... (TelechemInc., OR) were used for printing the cDNA clones using 12ì 4 pin format, on a Virtek chip writer professional micro-arrayer in KemTek, Inc, MD. The printed slides underwentUV cross-linking, ... free of clinical signs of SHIV, altered baselinegene expression data may give clues to the pathogenesis of altered immune response to secondary infections. Studiesinvolving HIV-infected humans...
- 8
- 260
- 0
Báo cáo khoa học: "Coxsackievirus and adenovirus receptor expression in human endometrial adenocarcinoma: possible clinical implications" doc
... according to CAR positivity (positive vs nega-tive CAR staining), level of expression (high vs low level ofCAR expression) and staining intensity (mild vs moderateand intense CAR staining intensity) ... CARprotein by immunohistochemistry, while the potentialIntense immunostaining for CAR in tumor cells in representative endometrial adenocarcinoma cases (original magnification ì200)Figure 1Intense ... while the remain-ing 15 patients were remained disease free. All the exam-ined clinicopathological parameters are reported in Tables1, 2 and 3.ImmunohistochemistryImmunostainings for CAR...
- 8
- 294
- 0
Báo cáo khoa học: " Assessment of Epidermal Growth Factor Receptor (EGFR) expression in human meningioma" docx
... the sample exhibiting staining); 3 (41-60% of the sample exhibiting staining); 4 (61-80% of the sample exhibiting staining), and 5 (81-100% of the specimen stained). The findings of the immunoreactivity ... cells staining forEGFR and histopathologic subtype.What does overexpression of EGFR in tumors indicate?Carroll et al provide an explanation by examining EGFR expression in human meningiomas ... only in their behavior but also in their expression of EGFR[33]. Lusis et al in a report evaluating the expression ofEGFR in 41 meningiomas identified a relatively higherincidence of EGFR expression...
- 7
- 302
- 0
Báo cáo y học: "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes" ppt
... anti-inflammatory properties are used in human ther-apy, regulate in vitro CD36 expression. Aspirin increasesCD36 expression in lines of human THP1 macrophages [23],dexamethasone induces CD36 expression ... expression in human dendriticcells from healthy subjects [24] and atorvastatin increasesCD36 expression in human monocytes [36,37].According to the results of our study, the increase in mem-brane expression ... conditions.Mechanisms involved in the regulation of CD36 expression by TNFαSince PPARγ is a transcription factor that plays a key role in inducing membrane expression of CD36 on human mono-cytes [19], we investigated...
- 11
- 471
- 0
Báo cáo y học: "Genome-wide assessment of imprinted expression in human cells." potx
... recogniz-ing imprinting in mice using the non-equivalence ofmonoallelic expression in reciprocal mati ngs of inbredstrains but yi elded widely different esti mates of amountsof imprinted genes in ... parent-of-origin-determined expression. We also detected five novelimprinted genes and delineated regions of imprinted expression surrounding annotated imprinted genes. Moresubtle parent-of-origin-dependent ... ,837 windows measured in the fibroblasts, a totalof 549 were showing hig h AE. These candidate windowsfell into 254 distinct loci in LCLs and into 110 loci in fibroblast s (Tables S5 and S6 in...
- 14
- 397
- 0
Altered neuronatin expression in the rat dorsal root ganglion after sciatic nerve transection ppsx
... overexpression of Nnat in HAECs or in mouse carotid artery would induce increased expression of a panel of nuclear factor-kappaB (NF-κB)-regulatedgenes, including inflammatory cytokines, chemokines,and ... nerve in adultrats induced an increased expression of Nnat in DRGneurons, specifically in unmyelinated C-fiber and thinlymyelinated A-δ fiber neurons, the primary afferent neu-rons involved in ... imprinting gene stronglyexpressed mainly in neonatal developing brain, increasedits expression in adult rats DRGs after axotomy of sciaticnerve. Although it is not clear why Nnat expression wasincreased...
- 7
- 207
- 0
báo cáo khoa học: " Microarray-based analysis of microRNA expression in breast cancer stem cells" doc
... prepared f or H&E stainingand immunohistochemical staining. The tumors in theBCSCs group were positive for both EMA and SMA,indicating that they were included of both luminalepithelial and ... 26(29):4209-4215.27. French J, Stirling R, Walsh M, Kennedy HD: The expression of Ras-GTPaseactivating protein SH3 domain-binding proteins, G3BPs, in human breast cancers. Histochem J 2002, 34(5):223-231.28. ... Volinia S, Nenci I, Calin GA, Querzoli P, Negrini M, Croce CM: MicroRNA gene expression deregulation in human breast cancer. CancerRes 2005, 65(16):7065-7070.8. Gregory RI, Shiekhattar R: MicroRNA...
- 8
- 333
- 0
Báo cáo y học: "Altered protein expression in serum from endometrial hyperplasia and carcinoma patients" pdf
... carcinoma; HP: haptoglobin; HRG: histidine-richglycoprotein; IGFBP-4: insulin-like growth factor-binding protein 4; IHRP:inter-alpha-trypsin inhibitor family heavy chain-related protein; IPI:international ... theseproteins, including serum amy loid A (SAA), apolipopro-tein A-I V (ApoA4), antithro mbin III (synonymous withSERPINC1), and inter-alpha-trypsin inhibitor heavy chainH4 (ITIH4; synonymous with inter-alpha-trypsin ... 2010,17:47-55.33. Weiderpass E, Brismar K, Bellocco R, Vainio H, Kaaks R: Serum levels ofinsulin-like growth factor-I, IGF-binding protein 1 and 3, and insulin andendometrial cancer risk. Br J Cancer 2003,...
- 8
- 258
- 0
Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25