algorithms for computational biomechanics of the brain
Nanoparticles of biodegradable polymers for delivery of therapeutic agents and diagnostic sensitizers to cross the blood brain barrier (BBB) for chemotherapy and MRI of the brain
... determining the extent of the particles to cross the BBB To further investigate the potential for the nanoparticles to cross the BBB, animal testing is important and necessary The second part of the thesis ... rate of the PLGA copolymers are dependent on the molar ratio of the lactic and glycolic acids in the polymer chain, molecular weight of the polymer, the degree of the crystallinity, and the Tg of ... presence of an intact blood brain barrier at the proliferating edge of the tumor has been suggested to be one of the major contributing factors to the failure of chemotherapy in the treatment of central...
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Báo cáo y học: "Multivariate explanatory model for sporadic carcinoma of the colon in Dukes’ stages I and IIa"
... part of the study were the same as for the first part of the investigation [18] The diagnostic criteria for inclusion of the cases were positive endoscopy and biopsy; those of exclusion were the ... collaborators The fruit of that qualitative examination was the rejection of a total of controls and cases at the defining moment of the construction of the data package The fundamental cause was the lack ... piece of evidence for the control of the classification bias of this article (with regard to the selection of the controls) has been shown in the work Varol et al [27], where the normality of CA...
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Tài liệu Challenges of water resources management for downstream livelihood of the lower Mekong delta, VietNam pdf
... upstream, others think that is by sedimentation The losses of clam stocks were one of the biggest problems in the coastal area The reason for the losses was unknown and this creates a lot of frustration ... water reaches the depth of 2-4 meters The flood of 2000 caused losses of 2150 of rice, decrease of rice yield from 60 to 70 percentages In the year of 2002, 70 villages and 11.120 of fruit trees ... millions of people to whom water provides directly or indirectly the source of livelihood The Mekong immense water resources are one of the key factors for social and economic development in the region...
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Tài liệu Champions for Children State of the World’s Mothers 2011 docx
... basic tools Conditions for mothers and their children they need to break the cycle of poverty and in the bottom countries are grim On average, improve the quality of life for themselves, woman in ... permeated the forgotten communities in the mountains It’s the kind of poverty that we often associate with other parts of the globe It was thinking about this gap between my mother’s hopeful, forward-looking ... to break the cycle of povChina, Norway, Thailand and the United Kingdom erty and improve the quality of life for themselves, their use some form of modern contraception children, and for generations...
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Tài liệu Proposal for a DIRECTIVE OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL on Alternative Investment Fund Managers and amending Directives 2004/39/EC and 2009/…/EC ppt
... protection of the interests of members and others, are required by Member States of companies within the meaning of the second paragraph of Article 58 of the Treaty, in respect of the formation of public ... 0.02 % of the amount by which the value of the portfolios of the AIFM exceeds EUR 250 million Irrespective of the amount of the requirements set out in the first and second subparagraphs, the own ... order to reflect the net asset value of the shares or units of the AIF The rules applicable to the valuation of assets and the calculation of the net asset value per unit or share of the AIF shall...
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Tài liệu Báo cáo khoa học: "A COMPUTATIONAL VIEW OF THE COGNITIVE SEMANTICS OF SPATIAL PREPOSITIONS*" ppt
... construals of the same information in the process of conventional imagery (thesis 5) LEVEL OF SPECIFICITY The level of specificity of conventional imagery addresses the issue of the degree of detail ... DEPICTIONS Here the x-axis points direction of the halfaxis of the particular side of the reference axis in the DCS; and in the case of "in front of" y is the perpendicular direction in the horizontal ... addition to the constraint on the proximity of the LO and RO, projective prepositions place a constraint on the position of the LO relative to a particular side of the RO In the case of the intrinsic...
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Tài liệu Báo cáo khoa học: Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat docx
... abolished the internalization of the GFP-fused Tat protein but did not alter the uptake of the Tat CPP These biochemical evidences con®rmed a pathway for the entry of the Tat peptide unrelated to the ... lgámL)1 in the presence of 100 lM chloroquine in the cell culture medium For FACS analysis, the concentration of the recombinant protein was increased to lgámL)1 The internalization of the GST±Tat ... rightward shift of the signal was observed signifying a reduction of the uptake of the Tat peptide at low temperature Likewise, a threefold reduction of the uptake at °C has been reported for the Antennapedia...
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Measures for social inclusion of the elderly: The case of volunteering doc
... from the age of 75 years onwards the probability of involvement in © European Foundation for the Improvement of Living and Working Conditions, 2010 Measures for social inclusion of the elderly: The ... Final Act of the Treaty of Amsterdam Aims of the ‘Measures for social inclusion of the elderly’ project Even if it is apparent that the volunteerism of older people does not yet receive the attention ... European Foundation for the Improvement of Living and Working Conditions, 2010 Measures for social inclusion of the elderly: The case of volunteering In line with the main goal of the project, ‘good...
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The Affair of the Brains potx
... magic These are the lonely outposts of the farthest planets, and here when the outlanders gather to yarn the idle hours away their tales conjure up from the past that raw, lusty period before the ... acceptance of the astounding fact; he was too busy to make comment He was observing the buildings, the nature of them, the exits from the dome, how they could best be reached T HEY stood on the roof of ... In the middle of that night, when the pleasures of Porno were in full stride, there emerged suddenly, from one of the dark, crooked byways that angled off the Street of the Sailors, a squad of...
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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
... positioned in the ÔupÕ position rows and shows that in the presence of the substrate, rotation of Asp142 towards Glu144 lowers the pKa of the latter by 0.8 pH units The calculated effects of the D140N ... for the position of residue 142 [34] The pKa calculations indicate that the only candidate for a residue determining the basic arm of the pH-activity profile of the D142N mutant is Glu144 The ... Mutation of subsets of these conserved residues in various family 18 chitinases has shown for the majority that they are important for catalysis [20,26–31] However, the mechanistic roles of several of...
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Báo cáo khoa học: Two separate regions essential for nuclear import of the hnRNP D nucleocytoplasmic shuttling sequence ppt
... GST of D02 was 4.0 nm and the KD of DNS 9.2 nm, that is double that of D02 This larger KD was accounted for by the twofold larger kd of DNS than that of D02 and their nearly similar ka values The ... expressed for 22 h The cells were then fused with 3T3 cells and cultured for another h in the presence of cycloheximide Arrows point out the murine nucleus Panels a–f, fluorescent signals of the GFP- ... essential for the nuclear import Results on mt9 suggested that phosphorylation of the tyrosine residue is not related to the nuclear import Then, the role of these two residues PY in nuclear import of...
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Báo cáo khoa học: "Linguistically Motivated Features for Enhanced Back-of-the-Book Indexing" ppt
... permutation of the composing words for each index entry, looks up the frequency of that permutation in the book, and then chooses the one with the highest frequency as the correct reconstruction of the ... reduce the size of the data set, possibly eliminating the training instances that will have the least negative effect on the usability of the data set The first step to reduce the size of the data ... way, we identify the form of the index entries as appearing in the book, which is the form required for the evaluation of extraction methods Entries that cannot be found in the book, which were...
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Báo cáo khoa học: "A COMPUTATIONAL MODEL OF THE SYNTAX-PROSODY INTERFACE IN TOKYO JAPANESE" doc
... rules> For instance, the optionality of minor phrase formation follows from the inclusion of and in SPI the prosodic category word (0)) It is the prosodic word rather than the minor ... argued for by Briscoe (pc) on the basis of English These functional equivalence classes correlate closely with the relative heights of the two pitch peaks - - the tighter the connection between the ... degrees of accuracy Formulating and testing the predictions of diverse hypotheses with the system is easy due to the basic generative approach Further cycles of phonetic experiments and modelling of...
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Báo cáo Y học: Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene ppt
... activity in HepG2 cells The relative positions of the MREs within the promoter region of the WD gene are indicated in Fig The four MREs are located in the proximal region of the WD gene promoter ... in the forward orientation, and MREc and MREd in reverse orientation The effects of the mutiple MREs on promoter activity of the MT gene have been shown to be dependent on the position of the ... response of the MT gene to heavy metals [10,12], the presence of MREs in the promoter of the WD gene suggests that MREs and their cognate binding proteins function in the regulation of WD gene...
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Cancer incidence, mortality and survival by site for 14 regions of the world. pdf
... somewhat lower for AMRO and EMRO The estimates for these two 33 regions are being reviewed in more detail as part of the revision of the cancer burden estimates for Version of the GBD 2000 34 ... cancer of the trachea, bronchus and lung was the 10th leading cause of death in the world in 1990, being the third in the developed regions Smoking was estimated to be responsible for another 20% of ... numbers of cases for the year 2000 These data have been used to estimate the global burden of cancer as part of the Global Burden of Disease 2000 project (GD 2000) (12) Version estimates of cancer...
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Cancer of the Brain and Other Central Nervous System doc
... 25.10) For patients with other CNS cancer, the spine was the most common primary site (53.9% of total), followed by the brain (41.3% of total) and other (4.8% of total) Other CNS cancers in the brain ... category is made up of a mix of racial groups As with the brain cancer group, the proportion of whites with other CNS cancer was much higher than the proportion of blacks with the same disease However, ... 80 Brain cancer occurring in the frontal lobes (25.8% of total), temporal lobe (20.1% of total), parietal lobe (14.6% of total) and overlapping lesions of the brain (19.8% of total) were the...
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Báo cáo khoa học: "A Linguistic and Computational Analysis of the German "Third Construction"*" potx
... requires that they be popped only when they are either the root clause or they are the immediately embedded clause of the previously popped structure Before extending this approach to the extraposition ... the matrix clause, and then pop Vz** in the usual manner The grammar corresponding to the BEPDA of Figure is shown in Figure (the arrows again show the sequence of adjunctions): we see that the ... new stack on top of the stack of stacks, or a fixed number of stacks below and above a designated stack on the stack of stacks is removed and a new symbol is pushed on the top of the designated...
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Báo cáo khoa học: Sp3 transcription factor is crucial for transcriptional activation of the human NOX4 gene doc
... dramatically decreased by the deletion of GC-box1 The activity was further decreased by the deletion of GC-box2 (Fig 3B) As shown in Fig 3C, the transcriptional activity of the kb of the 5¢-flanking region ... decreased by the deletion of GC-box3, the GC-rich Fig Alignment of the 5¢-nucleotide sequences of the human, rat and mouse NOX4 genes The numbers on the left are nucleotide positions relative to the putative ... essential for transcriptional activation of the human NOX4 promoter Figure shows the alignment of the 5¢-flanking and 5¢-noncoding sequences of the human, rat and mouse NOX4 genes Compared with the...
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