... and oxidative capacity in cancer cells Cancer Res 2004, 64:985-993 35 Tomiyama A, Serizawa S, Tachibana K, Sakurada K, Samejima H, Kuchino Y, Kitanaka C: Critical role for mitochondrial oxidative ... Krajewski S, Santamaria G, Kim H, Zapata JM, Marusawa H, Chamorro M, Reed JC: The bioenergetic signature of cancer: a marker of tumor progression Cancer Res 2002, 62:6674-6681 11 Sanchez-Arago ... phosphorylation in the activation of tumor suppressors Bax and Bak J Natl Cancer Inst 2006, 98:1462-1473 Sánchez-Aragó and Cuezva Journal of Translational Medicine 2011, 9:19 http://www.translational-medicine.com/content/9/1/19...
... and oxidative capacity in cancer cells Cancer Res 2004, 64:985-993 35 Tomiyama A, Serizawa S, Tachibana K, Sakurada K, Samejima H, Kuchino Y, Kitanaka C: Critical role for mitochondrial oxidative ... Krajewski S, Santamaria G, Kim H, Zapata JM, Marusawa H, Chamorro M, Reed JC: The bioenergetic signature of cancer: a marker of tumor progression Cancer Res 2002, 62:6674-6681 11 Sanchez-Arago ... phosphorylation in the activation of tumor suppressors Bax and Bak J Natl Cancer Inst 2006, 98:1462-1473 Sánchez-Aragó and Cuezva Journal of Translational Medicine 2011, 9:19 http://www.translational-medicine.com/content/9/1/19...
... Langston AL, Reid IR: Pathogenesis and management of Paget's disease of bone Lancet 2008, 372:155-163 Hashimoto J, Ohno I, Nakatsuka K, Yoshimura N, Takata S, Zamma M, Yabe H, Abe S, Terada M, Yoh ... Fukunaga M, Cooper C, Morii H, Yoshikawa H: Prevalence and clinical features of Paget's disease of bone in Japan J Bone Miner Metab 2006, 24:186-190 Takata S, Hashimoto J, Nakatsuka K, Yoshimura ... day) was half of that used for the treatment of osteoporosis in Caucasians (10 mg per day) Thereafter, we reported that the therapeutic efficacy of this treatment was equivalent to that of a...
... cost of outpatient care Inpatient services Laboratory Imaging Non-ARV drugs Treatment and care Meals Total per patient annual cost of inpatient care Total Non-AIDS ART AIDS Total Non-AIDS AIDS ... were estimated from aggregated data We used the CostIt [19] spreadsheet to categorize and summarize data of hospital costs, and SPSS 14.1 software for statistical analysis of patient data Results ... The data clerk maintained the Clinic database; the community healthworkers monitored patients and made regular home visits AMH maintained a database of HIV patients who received care and treatment...
... size of the wheal of the SPT area was 50% or larger than that caused by histamine and had a minimum diameter of mm larger than the control, it was recorded as positive Serum analyses of total and ... case there was an unexplained syncope one day later In three of these cases there was a change in allergic sensitivity so that it was impossible later to reach an adequate maintenance dose again ... were asked to return for clinical examination, SPT and serological tests, regardless of status of completion of IT Many patients also met for an extra consultation at a later date for the same...
... clearly identifiable RECA-1+ vasculature was outlined in ImageJ The area of the outlined region of interest was calculated by the software, and this area was defined as vasculature-positive area ... using a general rat endothelial cell marker, and calculation of the vessel-positive area was performed in the ipsilateral and contralateral gray matter in vehicle- and bpV-treated animal groups ... work of Ramon y Cajal (Ramon y Cajal, 1928), and reinvigorated several decades later (David and Aguayo, 1981, Bray et al., 1987), showed that spinal axons regenerated into grafted peripheral nerve,...
... simplicity of the approaches described above, heat denaturation and aggregation of BLG upon heat treatment may hide putative sites of attack from the action of proteases, therefore leaving intact some ... Malorni, Nitti, G., Laezza, P., Pizzano, R A. , Chianese, L & Addeo, F (1995) Primary structure of ovine aS1-casein: localization of phosphorylation sites and characterization of genetic variants ... Kuwata, K., Li, H., Yamada, H., Batt, C .A. , Goto, Y & Akasaka, K (2001) High pressure NMR reveals a variety of fluctuating conformers in beta-lactoglobulin J Mol Biol 305, 1073–1083 11 Fontana, A. ,...
... that affect dental appearance and have an impact on participants' daily lives may not be captured by IOTN In addition, DAI has many more measures of malocclusion affecting the anterior teeth than ... individuals who have a DHC grade of or 5, or grade with an AC of or above All other cases were therefore classified as having no need For DAI, 10 occlusal traits were assessed and a score was obtained ... eruption, defects of cleft lip and palate as well as any craniofacial anomaly, Class II and Class III buccal occlusions, and hypodontia Only the highest scoring trait is used to assess treatment need...
... study of the effects of glatiramer acetate on magnetic resonance imaging–measured disease activity and burden in patients with relapsing multiple sclerosis European/Canadian Glatiramer Acetate ... practice and thus difficult to generalize Observational data obtained in ‘real-life’ are more informative on a patient’s chance to reach a pre-defined therapeutic goal As our patients were treated ... interpretation of data, drafted the manuscript, and has given final approval of the version to be published ES contributed to conception and design of the study, acquisition of data, interpretation of data,...
... infliximab in RA patients Concerning DMARDs other than methotrexate, use of sulphasalazine, of azathioprine and of all other DMARDs as a group were not associated with infusion reactions The association ... (visual-analogue scale), patient overall assessment (visual-analogue scale), physician's global assessment (five grades), and concomitant treatment with DMARDs and oral glucocorticoids Disease Activity ... http://arthritis-research.com/content/8/4/R131 Table Treatment characteristics and disease activity measures at baseline and at the infusion reaction in patients with RA and SpAs Number At treatment initiation At infusion reaction RA (n...
... Matsui-Sakata A, Ohtani H, Sawada Y: Receptor occupancy -based analysis of the contributions of various receptors to antipsychotics-induced weight gain and diabetes mellitus Drug Metab Pharmacokinet ... than both overall and early (2-4 weeks) changes on any appetite scale examined (Table 3) Adjustment of early appetite scale changes by early weight changes demonstrated that early appetite scale ... Karagianis J, Grossman L, Landry J, Reed VA, de Haan L, Maguire GA, Hoffmann VP, Milev R: A randomized controlled trial of the effect of sublingual orally disintegrating olanzapine versus oral...
... primary measure to assess the incidence of tardive dyskinesia (TD) The Barnes Akathisia Scale 18 was used to assess akathisia at baseline and during treatment The modified Simpson-Angus Scale was ... 1-7) for at least month; Barnes Akathisia global score of or greater at any postbaseline visit and a baseline score 3 at any postbaseline visit and baseline Stauffer et al BMC ... Prevalence of the metabolic syndrome among patients receiving clozapine Am J Psychiatry 2006, 163:1273-1276 Ananth J, Gunatilake S, Aquino S, Bach V, Costa J: Are African American patients at a...
... CHB was made according to the diagnostic standards from the National Program for Prevention and Treatment of Viral Hepatitis A total of 20 HLA -A2 + patients with CHB (8 women and 12 men; mean age ... cytometry Hepatitis B surface antigen (HBsAg), HBeAg, antiHBc, anti-HBe and anti-HBs were quantified by radioimmunoassay (Abbott Laboratories, Abbott Park, IL, USA) HBV DNA was measured using the Amplicor ... Diagnostics, Basel, Switzerland) with a detection limit of 300 copies/mL All patients were HBeAg positive and had never received anti-HBV therapy before At baseline, the average serum HBV DNA of...
... experiments, participated in analysis and interpretation of data, and helped to write the paper TvdPK participated in analysis and interpretation of data and analysis tools TC, DB, and BD participated ... and four months after start of therapy in EULAR good responder patients and EULAR poor responder patients Abbreviations AMC: Academic Medical Center; ANOVA: analysis of variance; DAS28: disease ... clinical response was assessed using the European League Against Rheumatism (EULAR) response criteria [15,16] Table 1: Characteristics of patients at baseline Array analysis (n = 15) Age, years...
... beginning of the ICA Begnning of the ICA Symptom Other aeurysms SAH PCA SAH No SAH No Hydrocephalus No Thalamic hematoma Collateral circulation VA→ECA→IC A Subclavian artery →CCA→ICA ECA→ICrA No SCA+AICA+PIC ... Shinkei Geka 2002;30:853-8 Yamanaka C, Hirohata T, Kiya K, et al Basilar bifurcation aneurysm associated with bilateral internal carotid occlusion Neuroradiology 1987;29:84-8 Kazumata K, Terasaka S, ... summary of the studies Table Clinical data for all cases in this study Case Study Kumagai et 1981 al Matsuzawa 1982 et al 54/F aortitis Yamanaka 1987 et al Ishibashi et 1993 al 10 71/F Arteriosclerosis...
... William Currie was a Visiting Professor, from Dalhousie University, Halifax, Canada and held a CIHR ⁄ CNRS International Scientific Exchange Scholarship from the Canadian Institutes of Health Research ... in (A) The percentage of the cell population with an FL2-H fluorescence greater than · 101 was recorded during the FACS analysis The percentage of decrease of DYm was calculated as the ratio of ... Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington’s disease Proc Natl Acad Sci USA 97, 9701–9705 Klement IA, Skinner PJ, Kaytor...
... resistant to one or more antivirals can originate naturally as a result of genetic mutations and natural changes in the virus The possibility ofa novel virus that is resistant to antiviral treatment ... range of different strategies regarding the use of antivirals that depend on the overall public health goals authorities wish to attain, the availability of antivirals, and other practical considerations ... emergence of resistance to antivirals Anticipating the inevitable appearance of direct internet selling from unregulated sources of antivirals and other medications What are the research and development...
... discontinuation or a dosage decrease after repeated administration ofa pharmacological agent Withdrawal syndrome can also be caused by the administration of an antagonist 9< EXECUTIVE SUMMARY Pain ... with cancer Metastatic spinal cord compression may be a cause of acute back pain and metastatic brain tumour can cause severe headaches Mucositis after chemotherapy or radiotherapy is also a frequent ... initial evaluation of pain and the implementation of the pain management plan > 34 Emotional disturbances, such as fear, anxiety and emotional stress, can be both a risk factor and an outcome of...