Bóa cáo y học: " Early apoptosis of blood monocytes in the septic host: is it a mechanism of protection in the event of septic shock" ppt

... elaborating a connection between the production of proinflammatory cytokines by monocytes and the intensity of the inflammatory process [3]. They alsolead to the assumption that increased apoptosis ... by monocytes acted by an autocrinemode eliciting apoptosis. Knowledge of apoptosis of cells of the immune system in sep-sis is derived mainly from animal studies. Initiation of apoptosis in ... Critical Care of the 'Evangelismos' General Hospital and in the 2nd Department of Critical Care of the 'ATTIKON' University Hospital of Athens. The study was approved by the...

Báo cáo y học: " Early management after self-poisoning with an organophosphorus or carbamate pesticide – a treatment protocol for junior doctors" potx

... myocardial infarctions may result. However, tachycardias are also caused by hypoxia, agitation, alcohol withdrawal, pneumonia, hypovolaemia, and fast oxime administration. Tachycardias are not a contraindication ... parameters are satisfactory, the patient hasreceived enough atropine and is 'atropinised'.Continuation of bolus atropine loading to reach atropinisationIf after 3–5 min a consistent ... urinary retention in an agitated confusedpatient; agitation may settle after insertion of the catheter.Care of the airwayIf a pesticide-poisoned patient is unconscious, place anendotracheal...

Báo cáo y học: "Early Induction of apoptosis with tobacco smoke and related products in A549 lung epithelial cells in vitro" potx

... Pryor WA: The free radical chemistry of cigarette smoke andtheir interaction of alpha-1-proteinase inhibitor. In Pulmonaryemphysema and proteolysis Edited by: Taylor JC, Mittman C. New YorkAcademic; ... and CSE significantly increased the concentration of Bax-α in the mitochondria.Conclusion: Tobacco smoke initiates apoptosis in A5 49 airway epithelial cells as a result of mitochondrial damage ... the magnitude of apoptosis measured.This difference may have relevance to the ability of tobacco smoke to induce apoptosis in airway epithelialcells since reports in the literature do not agree...

Báo cáo y học: " Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock" docx

... cytokines. The result is a production of pro-inflammatory cytokinesthat are b alanced by an array of anti-inflammatory cyto-kines. The coagulation pathway is also activated by LPS-mediated ... inflammation [51]. Apoptosis is initiated by two pathways: 1) a receptoractivated, caspase-8 mediated (extrinsic) pathway; and 2) a mitochondrial initiated caspase-9 mediated (intrinsic)pathway. ... prognostically. This study examined the association of early lactate clearancewith selected inflammatory, coagulation, apoptosis response biomarkers and organ dysfunction scores in severesepsis and septic...

Bóa cáo y học: "The incidence and outcome of septic shock patients in the absence of early-goal directed therapy" pdf

... nobreach of privacy or anonymity. The Austin Hospital is anurban, academic, teaching, tertiary care hospital with 800beds that is based in the city of Melbourne, Australia. The ED of the Austin ... on history, vital signs, laboratoryresults, treatment and details of outcome using the central lab-oratory database, the ICU patient information database, the hospital admissions and discharges ... database (which recordsall deaths) and the hospital cardiac arrests database. The severity of illness of the study patients was calculated using the Acute Physiology and Chronic Health Evaluation(APACHE)...

Tài liệu Báo cáo Y học: Progressive apoptosis in chorion laeve trophoblast cells of human fetal membrane tissues during in vitro incubation is suppressed by antioxidative reagents pptx

... ROSformation in the placenta and increases gradually duringpregnancy. The stress may serve as a signal to initiate andpropagate the in ammatory process and result in apoptosis of placental tissues. ... Toshio Yamakawa11Department of Biochemistry, Faculty of Pharmacy, Tokyo University of Pharmacy & Life Science, Tokyo, Japan;2Yoneyama MaternityHospital, Tokyo, JapanPreviously, we demonstrated ... U937 cell apoptosis bymaintaining mitochondrial integrity and function [43], andricin-induced apoptosis of U937 cells by maintaining anintracellular reducing condition by acting as a thiol supplier[44]....

Báo cáo y học: "Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading" ppt

... quantitative molecular analysis of the response of articular cartilage to increased joint instability and alteredmechanical loading, and thus to gain more insight into the very early stages of ... histological appearance of OA cartilage makes it obvi-ous that the severity of changes may vary with the location in the joint. It has been demonstrated in the rabbit knee jointthat there are differences ... excised with a hammer and chisel from the lateral and the medial femoral condyle and from the lat-eral and the medial tibial plateau. For molecular analysis,articular cartilage was shaved off...

Báo cáo y học: "Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin" pptx

... mechanism of synovialhyperplasia in early RA and other persistent inflammatoryarthritides.Th2-type cytokines have additional effects on synovial fibrob-lasts that may be relevant in early RA. ... pathological mechanisms operating at the onset of clinically apparent RA are distinct from those in other early inflammatory arthritides, and that these mechanisms aretransient. In addition, the present ... relatedcytokines in early RA and other early inflammatory arthritides,as well as established RA, suggests a pathological processthat is specific to early RA and that is transient. The Th2cytokine...

Báo cáo y học: "Early and late morbidity and mortality and life expectancy following thoracoscopic talc insufflation for control of malignant pleural effusions: a review of 400 cases" potx

... effusions. Tetracy-cline the agent used most commonly in the past, is nolonger commercially available. Many other chemothera-peutic agents such as doxorubicin, cisplatin and cytara-bine combination, ... [10,11]. The mortalityrate within 3 months was 3.7%, with Karnofsky Perfor-mance Status and delay between diagnosis of pleural effu-sion and pleurodesis to play a statistically significant role.According ... pleural catheter drain-age has established itself as a less expensive, minimallyinvasive, and palliative modality for the management of malignant pleural effusions. Dozens of recent publica-tions...

Báo cáo y học: "Early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation" pps

... made in the Dac ron graft. The remaining 2 patients had their proxi-mal SVGs attached to ascending aorta distal to the Dacron graft.TheaorticdiameterattheSTJ,thesiteofmaximaldilatation of the ... Tsujita-Kuroda Y, Bando K, Kobayashi J,Yamagishi M, Kitakaze M, Kitamura S, Miyatake K: Failure to preventprogressive dilation of ascending aorta by aortic valve replacement in patients with bicuspid aortic ... wrapping of mild to moderate ascending aorta dilatation at aorticvalve surgery is associated with early reversed remodel-ling of the remaining proximal and distal aorta, withoutany short-term...

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