báo cáo khoa học: "Population genetics of the metabolically related Adh, Gpdh and Tpi polymorphisms in Drosophila melanogaster : II. Temporal and Spatial Variation in an Orchard Population Karen M. NIELSEN A.A. HOFFMANN S.W. McKECHNIE" potx

Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf

... 2010)doi:10.1111/j.1742-4658.2010.07977.x Aeropyrum pernix K1, an aerobic hyperthermophilic archaeon, produces a cambialistic superoxide dismutase that is active in the presence of either of Mn or Fe. The crystal structures of the superoxide ... withsix ligands. The additional water occupied the postulated superoxide bind-ing site. The thermal stability of the enzyme was compared with superoxide dismutase from Thermus thermophilus, a thermophilic ... 2010 FEBS 599 Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability Tsutomu Nakamura1, Kasumi Torikai1,2,...

Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt

... compilation ª 2010 FEBS 4851 Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Yã) ... Auling G (1998) Clon-ing and sequencing of the nrdF gene of Corynebacterium ammoniagenes ATCC 6872 encoding the functionalmetallo-cofactor of the manganese -ribonucleotide reductase (Mn-RRase). ... chemistry involv-ing an array of diverse metallocofactors. The nucleotide reduction gene (nrdF) encoding the metallocofactor containing small subunit (R2F) of the Corynebacterium ammoniagenes ribonucleotide...

Tài liệu Báo cáo khoa học: Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase fromThermus thermophilus pdf

... thermophilus; TtAKb-free, Thr-free regulatory subunit of aspartate kinase from Thermus thermophilus; TtAKb-Thr, Thr-bound regulatory subunit of aspartate kinase fromThermus thermophilus. 3124 FEBS Journal ... diffraction; MjAK, aspartate kinase from Methanococcus jannaschii; TtAK, aspartate kinase from Thermus thermophilus; TtAKb, regulatory subunit of aspartate kinase from Thermus thermophilus; TtAKb-free, ... M (1999) Aspartate kinase- independent lysine synthesis in anextremely thermophilic bacterium, Thermus thermophi- Crystal structures of regulatory subunit of Thr-sensitive aspartate kinase A....

Tài liệu Báo cáo khoa học: Limited suppression of the interferon-b production by hepatitis C virus serine protease in cultured human hepatocytes pptx

... immunoblotting as described in Fig. 6C. The black and whitearrowheads indicate Cardif and the cleaved Cardif, respectively. (B)Cardif is cleaved by NS3-4A in the cured Oc cells. The Oc cellswere cotransfected ... (accession no. AB093555) were5Â-AAGCCATGATGAGCAACCTC-3Â and 5Â-GTGTCCTGTTCCTTCCTCCAC-3Â. The sequences of sense andantisense primers for RIG-I (accession no. NM_014314)were 5Â-AATGAAAGATGCTCTGGATTACTTG-3Â ... genome-length HCV RNA; Oc, cured cells which were created by eliminating genome-length HCV RNA from the O cells by IFN treatment; andOR 6c, cured cells which were created by eliminating genome-length HCV...

Tài liệu Báo cáo khoa học: Kinetic characterization of the ﬁrst step of the ribozyme-catalyzed trans excision-splicing reaction docx

... al. Kinetics of the trans excision-splicing reaction FEBS Journal 275 (2008) 31103122 ê 2008 The Authors Journal compilation ª 2008 FEBS 3119 Kinetic characterization of the first step of the ribozyme-catalyzed ... isolate the first reaction step (substrate cleavage) by preventing the second reaction step (exon ligation). In addition, the product of the first reaction step is actually the intermediate in the ... between the twosteps of the TES reaction The substrate guanosine to be excised (G1) and its2Â-OH group are required for the second step of TES [48], similar to (if not the same as) the role of the...

Tài liệu Báo cáo khoa học: Quantitative analysis of the experimental O–J–I–P chlorophyll ﬂuorescence induction kinetics Apparent activation energy and origin of each kinetic step Steve Boisvert, David Joly and Robert Carpentier doc

... analysis of the experimental O–J–I–P chlorophyll ﬂuorescence induction kinetics Apparent activation energy and origin of each kinetic step Steve Boisvert, David Joly and Robert Carpentier Groupe de Recherche ... related to the reduction of the PQ pool.ResultsAs reported in the literature, the I step of the O–J–I–P ﬂuorescence transient cannot be clearly distinguishedby visual analysis of the FI traces ... membranes can be modeled by the superposition of the exponential rise to analyzequantitatively the contribution of each phase. The amplitude and rate constant of each of the threephases can be...

Tài liệu Báo cáo khoa học: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation ppt

... presence of full-length DEC1 As DEC1 lacking the basic region interfered with full-length DEC1 for the transcriptional suppression in the absence of CLOCK/BMAL1 [9], we examined whether DEC1Dbasic ... for DEC1 suppressiveactivity against CLOCK/BMAL1-induced transcription. In addition, the N-terminal region of DEC1, including the bHLH domain, interacted with the C-terminal r egion o fBMAL1 in ... whereas the N-terminal region, containing the bHLHdomain, is not essential for the interaction.Dominant-negative DEC1 counteracts the suppression of CLOCK/BMAL1-induced transcription in the presenceof...

Báo cáo khoa học: Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7 doc

... The Authors Journal compilation ê 2010 FEBS 977 Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein Structural modularity, intrinsic disorder and phosphorylation ... importance as the guardian of the cellcycle and its clinical relevance in human cancers, struc-tural and thermodynamic understanding of the mecha-nisms of action of the Rb protein is far behind ... solution, integrated with structural data and the analysis of other cellu-lar and viral proteins, which provided information about the balance of interactions involving the Rb protein and how these determine...

Báo cáo khoa học: Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose ppt

... 2 thatdelineate the carbohydrate-binding cavity of the lectin protomer). A closer examination of the structure of the binding sites indicates that speciﬁcity of the Mora-ceae lectins is primarily ... monosaccharide-bindingsite. (B) Network of hydrogen bonds (dashes) anchoring Man to the amino acid residues of the monosaccharide-binding site of MornigaM. Structure of a jacalin-related lectin complexed ... agglu-tinating activity of MornigaM is intimately linked toits sugar binding properties the three-dimensionalstructure of MornigaM in complex with a simple sugarwas determined to decipher the structural...

Báo cáo khoa học: " Imaging evaluation of the liver using multi-detector row computed tomography in micropigs as potential living liver donors" pdf

... to this study. Imaging evaluation of the liver using multi-detector row computed tomography in micropigs as potential living liver donorsJung Min Ryu1,†, Dong Hyun Kim2,†, Min Young Lee1, ... reducing the frequency of complications during and after the transplantation [7,11,36]. The goal of this study was to demonstrate the liver imaging of Yucatan micropigs using the MDCT for assessing ... an individual patient, determine the condition of the liver of the micropigs and help predict patient prognosis. Therefore, we determined the standard values for the livers of micropigs using...

Báo cáo y học: "Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis" ppsx

... 3Research articleNegative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritisManuela ... the association of CCR5 d32 with the inflammatory response, joint erosion, and DNASE2. In the early RA cohort,CRP levels at the onset of disease were determined. Patientscarrying the deletion ... remain conflicting [6]. The goal of our study was, therefore, to investigate the influ-ence of the CCR 5d32 deletion on disease susceptibility and on the clinical course of RA in a large and clinically...

báo cáo khoa học: "Population genetics and the Cretaceous extinction " potx

... survival or extinction in the Cretaceous extinction appear to be mutation rate (exposure) and secondarily, popula-tion size, and these have applied also to previous and subsequent ... de-pended.Although the geomagnetic reversal pattern is proposed to be the proximal causeleading to the Cretaceous mass extinction and may also be the ultimate one, this theorydoes ... survived the Cretaceous extinction due to their nocturnal habits and/ or small body size. This is exactly in accordance with this theory based onpopulation genetics and is...

báo cáo khoa học: "Population genetics of the metabolically related Adh, Gpdh and Tpi polymorphisms in Drosophila melanogaster : II. Temporal and Spatial Variation in an Orchard Population Karen M. NIELSEN A.A. HOFFMANN S.W. McKECHNIE" potx

... and the allelic data at the Tpi Population genetics of the metabolically related Adh, Gpdh and Tpi polymorphisms in Drosophila melanogaster : II. Temporal and Spatial Variation ... 1984. Population genetics of the metabolically related Adh, Gpdh and Tpi polymorphisms in Drosophila melanogaster. I. - Geogra-phic variation in Gpdh and Tpi allele frequencies ... 1974. The distribution of vineyard populations of Drosophila melanogaster and D. simulans during vintage and non-vintage periods. Oecologia, 15, 1-16.MCKENZIE J., 1980. An...

báo cáo khoa học: "Population genetics of French brown trout (Salmo trutta L): large geographical differentiation of wild populations and high similarity of domesticated stocks" pot

... Normandy- ...

báo cáo khoa học:" Psychometric properties of the OLQ-13 scale to measure Sense of Coherence in a communitydwelling older population" potx

... manuscript and contributed to the analyses of the qualitative data. Allauthors read and approved the final manuscript.Competing interests The authors declare that they have no competing interests.Received: ... wereprobed to elaborate on the meaning and relevance of items and their in terpretation of the ques tions andanswering scales. Transcripts were made verbatim. Datawere analyzed for content in the ... individuals, aged 65 and older. Methods: The OLQ-13 scale was administered as part of a healt hy aging project for non-institutionalized peopleaged 65 years and older. Internal consistency and reliability...

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