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Báo cáo y học: "Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocyte" ppsx

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Báo cáo y học: "Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocyte" ppsx

... production of matrix metalloproteinase-13 in advanced glycation end product-BSA-stimulated osteoarthritis chondrocytesGene expression and production of matrix metalloproteinase-13 in advanced glycation ... phosphorylating activity of IKKβkinase in an in vitro activity assay and EGCG inhibited the AGE-mediated activation and DNA binding activity of NF-κB bysuppressing the degradation of its inhibitory ... may serve as lead agents in the design of more potent and effective inhibitors of proinflammatoryFigure 6 Epigallocatechin-3-gallate inhibits activation and DNA binding of NF-κB in advanced glycation...
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Báo cáo y học: "The proinflammatory cytokines IL-1β and TNF-α induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway" ppt

... significantly increased during CIA development.Figure 3Induction of Synoviolin (SYN) expression by proinflammatory cytokinesInduction of Synoviolin (SYN) expression by proinflammatory cytokines. ... some of thesecytokines may also be responsible for the induction of SYN expression. To test this hypothesis, we first examined theeffects of proinflammatory cytokines on the expression of SYN in ... factor-α (TNF-α) induce Synoviolin (SYN) expression via the Erk pathwayInterleukin (IL)-1β and tumor necrosis factor-α (TNF-α) induce Synoviolin (SYN) expression via the Erk pathway. (a) Synovial fibroblasts...
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Báo cáo y học: "Electronic patient record use during ward rounds: a qualitative study of interaction between medical staff"

... highlight therole of physical group formation and the ergonomics of eachsystem in facilitating or hindering group use of patient records.Materials and methodsBackgroundThe medical lead of the ICU ... that ward-round teams can do tobetter understand how their formations around technologyaffect interaction by constraining formation in unusual ways and then encouraging the team to discuss ... interaction analysis,observation, and interviews. Video-based interaction analysisis a technique intended 'to identify regularities in the ways in which participants utilize the resources of the...
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Báo cáo y học: " Laugh Yourself into a Healthier Person: A Cross Cultural Analysis of the Effects of Varying Levels of Laughter on Health"

... pertaining to age, gender, city of residence, annual income, and education were in- cluded. Specifically, age, gender and city of residence defined the parameters of the samples. Measurement of ... axis and neural supply of lymphoid tissues. (16) In a study performed by Berk LS, et al., they found increased blood levels of interferon-gamma in ten healthy fasting males after being shown ... and declaration of anonymity and confidentiality was presented to all participants. After completing the survey participants were given a briefing about the study. Any incomplete surveys of...
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Báo cáo y học: "Relationships between free radical levels during carotid endarterectomy and markers of arteriosclerotic disease"

... hydroxyl-amine spin trap 2-ethyl-3-hydroxy-2,4,4 trimethyloxazolidine (OXANOH) by gassing a 10 mM solution of the radical with hydrogen for 45 minutes in the presence of the catalyst platinum ... Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin In- vest 1994;94:2493-503. ... expressed in atherosclerotic plaques, mainly by macrophages and foam cells [3]. The MMP family is catalytically active, both in vitro and in vivo. The activity of MMPs is increased by gene transcription,...
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Báo cáo y học: "Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy"

... the polymorphism of cytokine genes such as interleukin 1B [23,24] and tumor necrosis factor A [25,26] and H. pylori seropositivity have been reported. Gab1 may affect the H. pylori infection ... pleckstrin homology domain, followed by a proline-rich region and multiple tyrosine phosphorylation sites that serve as binding sites for the SH2 domains of PI3-kinase, phospholipase Cγ, SHP2, and ... Helicobacter pylori (H. pylori) and gastric atrophy and cancer. This study investigated the associations of Grb2 associated binder 1 (Gab1) polymorphism and the combination of PTPN11 gene encoding src...
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Báo cáo y học: "Hepatitis C Virus Serologic and Virologic Tests and Clinical Diagnosis of HCVRelated Liver Disease"

... antibody detection and serological determination of the HCV genotype, and molecular assays that detect and quantify HCV RNA and determine the HCV genotype. Anti-HCV antibody testing and HCV ... Pasteur Institute, France. Jean-Michel Pawlotsky, MD, PhD, is Professor of Medicine at the University of Paris XII and the Director of the Department of Virology, of INSERM Unit U635 and of the ... combination of pegylated interferon (IFN) alfa and ribavirin [18]. The efficacy endpoint of hepatitis C treatment is the “sustained virological response” (SVR), defined by the absence of detectable...
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Báo cáo y học: "Postoperative pain scores and analgesic requirements after thyroid surgery: Comparison of three intraoperative opioid regimens"

... administered in all patients. Pain scores, opioid demand and the length of stay in PACU were assessed in a blind manner. Results: Post operative pain scores were significantly lower in the fentanyl and ... Duration of anesthesia, duration of surgery, intraoperative anesthetics requirements and time to extubation defined as the delay between the end of surgery and extubation. In the PACU Clinical ... efficient in reducing morphine consumption in this type of surgery, however the addition of a third non opioid analgesic drug in addition to paracetamol and nefopam could have made the endpoint of...
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Báo cáo y học: "Discriminating between elderly and young using a fractal dimension analysis of centre of pressure"

... person’s COP remains within allowable limits, the person will remain standing upright. Difficulty lies in deciphering the information contained within these traces and distinguishing one from ... easily presented and provides a simpler means by which to quantify a non-linear system and as such may be more readily accepted by clinicians. The potential of the fractal dimension analysis is yet ... characterised by constraining the degrees of freedom to control the system, and subsequent releasing of these degrees of freedom allowing for greater adaptability to their environment. These findings...
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Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects

Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"

... extracellular matrix and scavenging of free radicals [4,5]. However, recent data indicated a certain role played by undersulfated glycosaminoglycans, such as HA, on hydroxyapatite crystal formation ... and cytokines, which promote migration of in- flammatory cells, fibroblasts and endothelial cells into the damaged site. It has been showed that fibroblasts cultured in presence of increasing ... Hyaluronan in tissue injury and repair. Annu Rev Cell Dev Biol. 2007;23:435-61 22. Wisniewski H.G and Vilcek J. TSG-6: an IL-1/TNF-inducible protein With anti-inflammatory activity. Cytokine...
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