... difference in ligands with an indi-rect interaction was observed: Gln317 in rIAP-I, and Arg317 in rIAP-II. The His317 of hPLAP is known tobe indirectly associated with the M3 site and to main-tain ... alkalinephosphatase; GCAP, germ cell-type alkaline phosphatase; hPLAP, human placental alkaline phosphatase; IAP, intestinal alkalinephosphatase; M1, metal-binding site 1; M2, metal-binding ... human foetal intestinal alkaline phospha-tase. Comparison with the isoenzymes from the adultintestine and human tumour cell lines. Biochem J 211,553–558.36 Smans KA, Ingvarsson MB, Lindgren P,...