Báo cáo khoa học: Regulated expression by PPARa and unique localization of 17b-hydroxysteroid dehydrogenase type 11 protein in mouse intestine and liver pdf
Báo cáo khoa học: Regulated expression by PPARa and unique localization of 17b-hydroxysteroid dehydrogenase type 11 protein in mouse intestine and liver pdf
... blot50CBB-stain3725IntestineLiver+ ++ +Wy14,64317β-HSD11CBB-stainBAFig. 1. Effects of Wy14 643 on protein expression levels of 17b-HSD11 in the liver and intestine of mice. (A) Specificity of ... 17b-HSD11 is shown in Fig. 1B. The amounts of 17b-HSD11 protein were markedly induced in both the mouse intestine and liver by administration of the PPARa agonist. The induction ratios in both tissueswere ... levels of 17b-HSD11 in the liver and intestine. The same amounts (20 lg) of proteins from the PNS frac-tions of liver and small intestinal mucosa were analyzed by westernblotting using antibodies...
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Tài liệu Báo cáo khoa học: "An ISU Dialogue System Exhibiting Reinforcement Learning of Dialogue Policies: Generic Slot-filling in the TALK In-car System" pot
... Exhibiting Reinforcement Learning of DialoguePolicies: Generic Slot-filling in the TALK In- car SystemOliver Lemon, Kallirroi Georgila, and James HendersonSchool of InformaticsUniversity of Edinburgholemon@inf.ed.ac.ukMatthew ... tions of both systems, in o rder to construct an interface be-tween the learnt policies for COMMUNICATO R and the in- car baseline system.5.2 Mapping between COMMUNICATOR and the In- car DomainsThere ... number of researchthemes, in particular: using learnt dialogue policies,learning dialogue policies in online interaction withusers, fragmentary clarification, and reconfigurability.3.1 Moving...
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Báo cáo khoa học: Increased expression of c-Fos by extracellular signal-regulated kinase activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis pot
... N-terminal kinase, showed no effecton the DNA binding of c-Fos and c-Jun induced by treatment with ATZ + mercaptosuccinic acid, indicat-ing that JNK is not involved in the binding of AP-1 tothe ... c-Jun. In thisexperimental model, ERK was activated for 9 h afterthe addition of ATZ + mercaptosuccinic acid, owingto inactivation of protein tyrosine phosphatase caused by sustained increases in ... mercaptosuccinic acid-induced luciferaseactivity was attenuated by mutation of the activator protein- 1 binding site in the bim promoter region. The amounts of total and phosphorylatedc-Fos increased...
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Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt
... transformants. Protein techniques Protein was determined by protein- dye binding with BSA asa standard [47]. Whole cell protein of C. ammoniagenes cellswas isolated from 2 mL of induced culture. ... suggesting thatthe heterologous expression of genes encoding metallo-proteins can lead to incorrect metal ion incorporation.This is observed in rubredoxin and desulforedoxinswhere zinc, instead ... of protein uti-lizing the principle of protein- dye binding. Anal Bio-chem 72, 248–254.48 Laemmli UK (1970) Cleavage of structural proteinsduring the assembly of the head of bacteriophage T4.Nature...
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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
... in thepresence of RNAse. Interestingly, most of the identi-fied proteins are known to be involved in RNA metab-olism and belong to three large families of RNA-binding proteins. These proteins ... involved in protein protein interactions and sub-cellular targeting [3,4]. TIA-1-related (TIAR) protein belongs to the RNA recogni-tion motif (RRM) family of RNA-binding-proteins. Itis a shuttling ... TIAR-Flag, both in the absence and the presence of RNAse A, therebyindicating that TIAR association with these proteins isspecific and reliant on protein protein interactions. By contrast, DDX21...
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Tài liệu Báo cáo khoa học: Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft doc
... each binding ligand in its own way and swings outonly as much as is mandatory.Results and DiscussionCrystals of the complex of stefin A and cathepsin Bcontain complete wild -type protein sequences. ... position of the two occluding loophistidines, H110 and H 111. Instead of a parallel posi-tioning within the active site cleft, these two sidechains now point in different, almost opposing direc-tions. ... the inhibition of the enzyme by their endoge-nous protein inhibitors cystatins and stefins [21].A further step in understanding of these mechanismswas provided by the crystal structures of human...
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Tài liệu Báo cáo khoa học: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism pptx
... transcripts(ACMSD I and II) has been examined in human brain, liver and kidney.Both transcripts are present in kidney and liver, with highest expression occurring in kidney. In brain, no ACMSD II expression ... the bacterial protein [21,33].Interestingly, the same difficulty in stripping off themetallocofactor from the protein has been describedfor murine adenosine deaminase, a member of theamidohydrolase ... (2002) Expression of rat hepatic 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase isaffected by a high protein diet and by streptozotocin-induced diabetes. J Nutr 132, 115 3 115 9.30 Shin...
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Tài liệu Báo cáo khoa học: Differential expression of duplicated LDH-A genes during temperature acclimation of weatherfish Misgurnus fossilis Functional consequences for the enzyme ppt
... Molecu-lar cloning and cold-inducible gene expression of ferritinH subunit isoforms in rainbow trout cells. J Biol Chem271, 26908–26913.13 Tang SJ, Sun KH, Sun GH, Lin G, Lin WW & ChuangMJ ... chan-ged by affecting rates of transcription and ⁄ or transla-tion and ⁄ or mRNA and protein degradation. Thisrepresents a quantitative strategy to offset the lack orexcess of kinetic energy ... tele-osts, including weatherfish, zebrafish and others, tissue-specific light myosine chain forms are encoded by par-alogous genes mlc1 and mlc3, whereas in amphibians,birds and mammals these proteins...
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Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx
... ferritin expression in nonpermeabilized (thin lines,– saponin) and permeabilized cells (thick lines, + saponin) cells cul-tured without and with iron as indicated. (D) Perls’ staining of cyto-spins ... trafficking is inde-pendently regulated by an intrinsic CD1d-encoded tyro-sine motif and by the invariant chain. Immunity 15,897–908.40 Kang SJ & Cresswell P (2002) Regulation of intracellu-lar ... in iron-rich mediashowed a further increase in ROS production as deter-mined by an increase in DCFH mean fluorescenceintensity (Fig. 2B, thick line). In addition, determin-ation of acrolein...
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Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx
... 25 min prior to 5 min of treatment with10 lm serotonin (Fig. 6B). Increasing the free intracel-lular levels of Ca2+ by treatment of HEK293 cells withthapsigargin induced phosphorylation of ... (Fig. 4A). Inter-estingly, neither inhibiting phosphorylation of Ser916 by mutating the amino acid to alanine, nor poten-tially mimicking it by mutation to aspartic acid orglutamic acid, in uenced ... FEBSexpressed in mammalian cells may become activated by members of the Ras family of small G proteins.The activity of Ras proteins is under tight control of several classes of guanine nucleotide...
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Từ khóa: Nghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ