Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... hyperphagia and high-fat feed-ing induces expression of RMI1 and E2Fs in adipocytes, and causes a positive interaction between the molecules. Increasedexpression of RMI1 and E2Fs regulates the cell ... clinical course of some types of obesity. In this minireview, we focus on adipocyte hyperplasia as a novel therapeutic target for the treat-ment of obesity and discuss the merits of targetingrecQ-mediated ... via an interaction with E2F path-ways, at least in part, suggesting the involvement in the regulation of adipocyte hyperplasia. RMI1 expres-sion is induced by glucose in vitro, and its in vivoexpression...
- 5
- 558
- 0
Tài liệu Báo cáo khoa học: Domain deletions and substitutions in the modular protein evolution doc
... domain deletions are more com-mon at either of the protein termini, and that theiroccurrence is slightly higher at one of the termini,depending on the number of domains in the protein and the ... combinations are the P-loopnucleotide triphosphate hydrolase domain, the epider-mal growth factor (EGF) domain, the SH3 domain, the P-kinase domain and the domains involved in the blood clotting ... missing anywhere in the arrangement. Then we calculated the frequency of the deletion at each domain position within the group of proteins containing a given number of domains.We found that the...
- 11
- 608
- 0
Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx
... in ammation induces a state of ‘leptin resistance’ in obese animals and humans resulting in development of hyperleptinemia. Similarly, hyperleptinemia is aconsequence of the development of insulin resistance in ... overexpression of ANG-PTL6 ⁄ AGF in the liver of diet-induced obese miceresults in elevated ANGPTL6 ⁄ AGF serum levels and amelioration of diet-induced obesity and insulin resis-tance [14]. Taken together, ... N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain,both characteristic of angiopoietins. ANGPTLs do not bind to either the angiopoietin receptor Tie2 or the related protein Tie1,...
- 6
- 609
- 0
Báo cáo khoa học: "Case markers and Morphology: Addressing the crux of the fluency problem in English-Hindi SMT" pot
... Proceedings of the 47th Annual Meeting of the ACL and the 4th IJCNLP of the AFNLP, pages 800–808,Suntec, Singapore, 2-7 August 2009.c2009 ACL and AFNLPCase markers and Morphology: Addressing the ... likely. The separation of the lemma and suffix helps in tiding over the data sparsity problem by allowing the systemto reason about the suffix-case marker com-bination rather than the combination of ... described in table 1 was used for the experiments. The SRILM toolkit2was used to create Hindilanguage models using the target side of the train-ing corpus.Training, tuning, and decoding were...
- 9
- 465
- 0
Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc
... to the induction of oxidative stress during ischemia ⁄ reperfusion in brain.There is a growing body of information concerning the mechanism of ROS generation by the respiratorychain in mitochondria. ... this treatment. The high degree of protection by ADP sug-gests that the mitochondrial injury is caused by open-ing of the mPTP. There is evidence that ADP inhibitsopening of the mPTP by occupying binding ... and oxygen consumptionwas analysed. The corresponding values are shown in Fig. 1. After 15 min of incubation in the presence of 3.5 lm Ca2+ in an air atmosphere, state 3 respiration of brain...
- 9
- 433
- 0
Báo cáo khoa học: "Annotation Schemes and their Influence on Parsing Results" docx
... Corpus, parsing one of the treebanks while having trained on the other one.He draws the conclusion that a small amount of matched training data is better than a large amount of unmatched training data. ... testset, all other sentences go into the training set.4.1 Preprocessing the TreebanksSince we want to read the grammars for our parserdirectly off the treebanks, preprocessing of the treebanks ... (Klein and Manning, 2003) on two Italian treebanks. They re-port disappointing results which they trace back to the different difficulties of different parsing tasks in Italian and English and...
- 6
- 331
- 0
Báo cáo khoa học: Membrane compartments and purinergic signalling: the role of plasma membrane microdomains in the modulation of P2XR-mediated signalling pot
... overview of the properties of lipid rafts and how they arestudied, along with recent advances in the understanding of their role in modulating P2XR-mediated signalling.AbbreviationsENaC, epithelial ... regions within the bulk of fluid membrane and which are enriched in cholesterol and (glycero-)sphingolipids. In addition the fatty acid chains of the phospholipids composingthese rigid domains are ... thanthose in the lipids of the surrounding membrane. In fact, this fatty acid composition favors a tighter pack-ing of phospholipids and cholesterol, increasing the rigidity of these domains [32–35]....
- 11
- 542
- 0
Tài liệu Báo cáo khoa học: Human intrinsic factor expressed in the plant Arabidopsis thaliana doc
... 0.2MNaH2PO4pH 7.5.Measurement of Cbl binding capacity and relativeaffinity of Cbl and Cbi to IF The binding capacity was measured by using57Co-cobalamin (Cbl*) [23]. Binding of Cbl and its analogueCbi ... removal of aDNA fragment containing the Gmlbc3 promoter, the gusA gene, and the pAnos termination sequence bydigestion with HindIII; the digestion was followed by self-ligation of the remaining ... at the internal site …PSNPflGPGP. The key properties of the preparation obtained were identical to those of native IF: the binding curves of vitamin B12to recombinant IF and gastricIF were the...
- 6
- 492
- 0
Báo cáo khoa học: "PARSING VS. TEXT PROCESSING IN THE ANALYSIS OF DICTIONARY DEFINITIONS" pot
... already present in the LSP grammar. Figure 1 shows a sample definition and the triples the parser found in it. ABDOMEN 0 1 N THE PART OF THE BODY BETWEEN THE THORAX AND THE PELVIS (THE) pmod ... the node to the right of the taxonomy marker 'W") serving as a pointer to its own defining node. The resulting network is quite dense. We simplify by leaving out other parts of the ... for making inferences; (2) syntactic relations between the defined word and various defining words, such as (in a verb definition) the direct object of the head verb, which we will investigate...
- 8
- 461
- 0
Báo cáo khoa học: "A Memory-Based Approach to the Treatment of Serial Verb Construction in Combinatory Categorial Grammar" pdf
... CCG in §2, and then mo-tivate the need of memory mechanism in dealingwith serial verb construction in CCG in § 3. I de-scribe the hybrid model of CCG and the filler-gapmemory in §4. I then ... the gap ✸.There are two constraint parameters in eachmodality: the combinatory directionality d ∈ {<, >} and the syntactic category c, resulting in the filler and the gap denoted in the ... category. The fillers and the gaps are then associated in the coordination and the serialization rules. This re-sults in a more flexible way of dealing with intra-sentential ellipses in SVC than the...
- 9
- 572
- 0
Từ khóa: mutuality and motivation in the treatment of eating disordersart science and innovation in the treatment of early traumad vitamin d receptor and cathelicidin in the treatment of tuberculosisbáo cáo khoa họcbáo cáo khoa học mẫubáo cáo khoa học y họcNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2chuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘITÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ