... fromstress-induced damage by preventing protein denatur-ation and ⁄ or repairing such damage [1]. Mammalianheat shock proteins are classified into several familieson the basis of their apparent ... activator of transcription-3Nobuyuki Yamagishi, Hajime Fujii, Youhei Saito and Takumi HatayamaDepartment of Biochemistry & Molecular Biology, Division of Biological Sciences, Kyoto Pharmaceutical ... element; HSF, heat shock factor; INFa, interferon a; JAK, Janus kinase; NLS, nuclear localization signal;siRNA, small interfering RNA; STAT, signal transducer and activator of transcription.5870...