... during aging, no changewas observed using succinate. In the presence of 2,4-dinitrophenol, oxygen consumption rates were the same in the presence of ADP (state 3) at each age.Together, these ... increased with increasingage (27-month-old rats). Among the glycated proteins,trails of isoforms appeared, in agreement with modifi-cations targeting the basic amino acids arginine andlysine, ... role in aging, both by producing intracellu-lar reactive oxygen species (ROS) and by being the most adversely affected organelles during aging [3]. The electron transport chain located in the inner...