what is the trend in reactivity of the group 1 elements with water
Báo cáo khoa học: Structural characterization of the large soluble oligomers of the GTPase effector domain of dynamin potx
... ‘assembly’domain and a proline-arginine rich domain at the extreme carboxy-terminal end. The GTPase domain is the most highly conserved domain within the members of the dynamin family. The functional ... dynamin assembles in the form of ringsaround the necks of budding vesicles, and then a con-formational change in the dynamin collar aids the scis-sion of the vesicle from the parent membrane. The coiled-coil ... to bind the middle domain of dynamin [7]. The above possibility of functional dissection of the dynamin protein into specific domains suggests that adetailed characterization of the intrinsic...
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Báo cáo khoa học: Revisiting the 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence doc
... exchange2 21 194 13 n6 12 1 11 9 2n7 18 24 36n8 net 913 48n8 exchange 410 > ;10 0n9 net)3 )567n9 exchange 10 15 5 > 10 0n 10 net)6 )838n 10 exchange 12 4 4898 > 10 0n 11 net)6 )838n 11 ... v 12 A3ịn9bẳ v9fỵ v 10 bỵ v 12 A4ịn 10 fẳ v8bỵ v 10 bỵ v 13 A5ịn 10 bẳ v8fỵ v 10 fỵ v 13 A6ịn 11 fẳ v 14 bỵ v 15 A7ịn 11 bẳ v 14 fỵ v 15 A8ịn 12 fẳ v 14 fỵ v 16 A9ịn 12 bẳ v 14 bỵ ... either f6p or p5p,while in the traditional model they can only originatefrom p5p. In a 13 C-labeling experiment with 10 0% 13 C 1 glucose this will result in the synthesis of unlabeled and 13 C 1 -labeled...
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A Compilation of the Messages and Papers of the Presidents Section 3 (of 3) of Volume 8: Grover Cleveland, First Term. pptx
... January, 18 85, in relation to the management and conduct of the office of district attorney of the United States for the southern district of Alabama." The incumbent of this office on the 1st ... promptly to inform the Commission, in writing, of the removal or discharge from the public service of any examiner in his office, or of the inability or refusal of anysuch examiner to act in that ... custody, nor is there magic in the undefined and sacred solemnity of Department files. If the presence of these papers in the public offices is a stumbling block in the way of the performance of Senatorial...
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Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
... concentrations of 12 5I-labeled STY72Ffor 1 h at 37 °C in binding buffer(50 mMHepes, pH 7.5, 4 mMMgCl2, 0 .1% bovine serumalbumin, 10 lgặmL )1 leupeptin, 10 lgặmL )1 aprotinin).Following incubation, ... 10 000 g for 1 h at 4 °C. The pellet obtainedwas resuspended in buffer containing 50 mMHepes,pH 7.5, 5 lgặmL )1 soybean trypsin inhibitor, 5 lgặmL )1 leupeptin, 5 lgặmL )1 aprotinin and 10 0 ... andnonessential amino acids for 12 h in the absence of STpeptide, and in the presence of cycloheximide (10 0 lgặmL )1 )or swainsonine (10 lgặmL )1 ). Cells were either re-stimulated with ST peptide,...
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Mobil 1 is original equipment in some of the world’s finest vehicles, including potx
... maximum350300350200 15 0 10 0500 10 0%90%80%70%60%50%40%30%20% 10 %0% 21, 000 21, 00042,00042,00084,00084,000 12 6,000 12 6,000 16 8,000 16 8,000 210 ,000 210 ,00063,00063,000 10 5,000 10 5,000 14 7,000 14 7,000 18 9,000 18 9,0002 31, 0002 31, 00000 ... longer-lasting engines. In 19 74, Mobil 1 synthetic engine oil was born. The power of Mobil 1 technology gives you the most advanced engine protection in three ways:ã Keeps Your Engine Performing ... than any other brand.ã Consistently bring new innovations to the market to meet the latest needs in engine oil.Discover the Mobil 1 Difference What s the Synthetic Difference?SyntheticsUniform...
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Báo cáo Y học: The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73 pdf
... [‡ 7] 1. 1 · 10 )10 b3.2 · 10 )4cP74G £ 2.4 · 10 )11 (7) (4.6 ± 0.2) · 10 6 (10 )[0.9]£ 1. 1 · 10 )4cQ76G £ 1. 1 · 10 )11 (8) (6.3 ± 0.2) · 10 6(9) [1. 2]£ 6.9 · 10 )5cN77G £ 1. 1 · 10 )11 (8) ... · 10 )7(3)[0.5] [1. 2] [0.6]Cathepsin L Wild-type £ 1 · 10 )11 a5.2 · 10 6a£ 5 · 10 )5a [1] [1] [1] L73G (1. 09 ± 0.08) · 10 )10 (10 ) (2.98 ± 0.04) · 10 6 (10 ) (3.4 ± 0.4) · 10 )4(3)[‡ 11 ] ... Search FixingÕ of the side chains within the Leu73–Asn77 segment in the second binding loop of cystatin A. After each of these steps, the conformation of the second binding loop in the complex...
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Báo cáo khoa họcRe-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme docx
... 0 .11 4 ± 0. 012 17 9 0.57 ± 0.06 0.26 ± 0. 01 2 .19 81. 7F238S 7.0 17 .6 ± 0.3 1. 25 ± 0.46 14 .1 0 .12 5 ± 0.04 1. 1 ± 0.7 0 .11 3 12 5P262S 7.0 23.0 ± 1. 4 1. 04 ± 0 .13 23.0 0.457 ± 0.05 1. 23 ± 0.22 0.3 71 ... SwitzerlandProgram in Neurosciences & MentalHealth, Hospital for Sick Children, Toronto,Canada(Received 5 March 2 011 , revised 21 April2 011 , accepted 9 May 2 011 )doi :10 .11 11/ j .17 42-4658.2 011 .0 817 2.xClostridial ... splitting off the nicotinamide ring, suggestingthat the covalent bond between the nicotinamide and the ribose of the coenzyme is particularly labile. The signal of the parental molecule is also visible...
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Báo cáo khoa học: Mass spectrometric characterization of the covalent modification of the nitrogenase Fe-protein in Azoarcus sp. BH72 ppt
... electrophoresis.Another striking difference of the MALDI-TOF spec-tra from the modified Fe-protein in comparison to the unmodified Fe-protein is the decreased intensity of peak 16 25.4 m ⁄ z and the absence of ... absence of peak 16 16.3 m ⁄ z can beexplained again by the inability of trypsin to cleaveC-terminal to R102 due to the modification at this resi-due. However, the presence of peak 16 25.5 m ⁄ z in the spectrum ... PAGE analysis, indicating hydrolysis of the modification under these conditions even in the absence of TFA (see Supporting information, Fig. S1and Doc. S1). The LC liquid phase which containedformic...
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Báo cáo khoa học: Functional studies of crustacean hyperglycemic hormones (CHHs) of the blue crab, Callinectes sapidus – the expression and release of CHH in eyestalk and pericardial organ in response to environmental stress pot
... decrease in CHH expres-sion in the ES is in proportion to that of CCAPexpression in the same tissue, as described in Chunget al. [47], but there is no change in CCAP of TG,indicating the tissue-specific ... (http://www.dnr.state.md.us/bay/monitoring /water/ index.html). In particular, it is notedthat in the Bay, low temperatures during winter andanoxia during summer, in combination with the changes in salinity, are associated with ... ranging from 1 : 5 for Cal. sapidus,to1: 8in Car. maenas,to1 :10 inCan. pagurus [29,30], yieldingpeak 2 as the major CHH. The immunohistochemistry studies show that the intrinsically staining cells...
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Báo cáo khoa học: Structure and topology of the transmembrane domain 4 of the divalent metal transporter in membrane-mimetic environments docx
... found in most of the structures of the 16 conformers at pH 7.5 in the segment of Leu9–Val17, except Ile12 and Phe16 in some of the conformers.Table 1. Structural statistics for DMT1-TM4 in the ... toexplore the molecular biology aspects of DMT1 since the discovery of this gene, there has so far been no structuralcharacterization of either this integral protein or a segment of it. Analysis of the ... 2004 Structure and topology of TM4 of DMT1 (Eur. J. Biochem. 2 71) 19 51 peaks of Ile10, Ile12 and Val17. This suggested that the peptide was inserted in the interior of micelles. However,little...
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Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf
... confirmed the results obtained in the pull-down assays, showing that there is a physicalinteraction between the N- and C-terminal domains of SSIII in vitro.Mapping of the CD-binding region in the N-terminal ... starch-binding domain;CD, catalytic domain; D123, N-terminaldomain containing the three SBDs; D23,truncated isoform lacking the D1 domain;CD–St2 .1, CD–2.2 and CD–2.3, truncatedproteins lacking ... starch-binding domains, particularly the D( 316 –344) and D(495–535) regions, with the catalytic domains, as wellas the full integrity of the starch-binding capacity of the D2 domain, areinvolved in...
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Báo cáo khoa học: Change in structure of the N-terminal region of transthyretin produces change in affinity of transthyretin to T4 and T3 pdf
... revised 14 June2006, accepted 3 July 2006)doi :10 .11 11/ j .17 42-4658.2006.05404.x The relationship between the structure of the N-terminal sequence of trans-thyretin (TTR) and the binding of ... to02468 10 12 14 0 10 203040506070800.00.5 1. 0 1. 52.02.53.00 5 10 15 20 25 30 35 40 45 500.00 .1 0.20.30.40.50 5 10 15 20 250.00 .1 0.20.30.40246 810 1 214 160.00.5 1. 0 1. 52.02.53.00 ... 7G.Discussion The binding of thyroid hormones is one of the mainfunctions of TTR, which is functionally integrated with albumin and thyroxine-binding globulin as a networksystem to ensure the appropriate...
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báo cáo hóa học: " Initial validation of the Argentinean Spanish version of the PedsQL™ 4.0 Generic Core Scales in children and adolescents with chronic diseases: acceptability and comprehensibility in low-income settings" pdf
... 0.5 18 6 0.80Emotional 65 ± 21. 31 0 10 0 0.5 5.3 208 0.59Social 69 .1 ± 21. 67 10 10 0 0 11 .1 203 0.59School 65.6 ± 21. 3 10 10 0 0 5.2 18 9 0.62Proxy-ReportTotal 73.36 ± 16 .09 14 10 0 0 1. 7 18 3 ... 72.72 (14 . 21) 66.87 (16 .74)0. 011 71. 64 (17 .13 )58.54 (15 .8) 71. 31 (17 .07)65 .16 (15 .45)65.29 (19 .96)68.98 (15 .22)SCT, HIV > COPD*Physical 75.42 (15 .93)67.76 (19 .60)0.004 74.24 (17 .08)58 .16 (19 .84)74.58 (18 .05)60.98 (19 .44)67 .17 (1. 32)72.03 (15 .84)SCT, ... 4 10 0 0 10 .1 272 0.78Psychosocial 72. 41 ± 16 .45 18 10 0 0 2.4 18 9 0. 81 Emotional 69 .16 ± 19 .6 5 10 0 0 6.3 285 0.66Social 77.78 ± 20.73 5 10 0 0 20.2 283 0. 71 School 68.74 ± 24 5 10 0 0 1. 7 19 2...
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