... therapy in the more mature inflammatory lesions where reparation is already underway The overall outcome for the individual patient is then little changed at the level ofthe entire spine Lack of impact ... the context ofthe histopathological evolution of an inflammatory lesion in the spine Early lesions have features of synovial and subchondral marrow inflammation that is followed by erosion of ... impact of adalimumab on BALP in pre-radiographic disease is consistent with this hypothesis This raises the concept of a window of opportunity for disease modification in AS using anti-TNF therapy...
... To the others in the fossil fields, however, the evidence that there had been these die-offs in the past seemed overwhelming But what were the causes of these events? Could all have been the ... near the end of some otherwise solid talk about yet another new K-T section, then at the ends of papers, the view that impact was a cause not only ofthe 35 UNDER A GREEN SKY K-T but also of others, ... most useful of these would be sections with the largest variety of fossils available As it turned out, some ofthe best of these in the world were the Basque seacoast cliffs Wiedmann was the geologist...
... causes global oceans to be enriched in 18O As a result, global oceans at the peak ofthe last glacial period had δ18O ~1‰ more positive than at present 21 Climate over the last 65 Myr (beware the ... to the Fourth Assessment Report ofthe Intergovernmental Panel on Climate Change, Figure 3.8 Cambridge University Press Used with permission Recent observations: Drought Climate Change 2007: The ... 2007: The Physical Science Basis Working Group I Contribution to the Fourth Assessment Report ofthe Intergovernmental Panel on Climate Change, Figure SPM.3 Cambridge University Press Used with...
... methods have also been used, including the dynamic measurement ofthe initial rate of GdDTPA enhancement and maximal enhancement, both of which are useful surrogates for the degree of synovial vascularity ... be prevented used, including the quantitative measurement of synovitis by the evaluation of its thickness in millimetres, calculation ofthe volume of a given slice, or estimating the entire joint ... rheumatoid arthritis and other arthropathies The ability of MRI to demonstrate synovitis in RA is the greatest strength of this method over projection radiography The presence of synovitis can be inferred...
... desire to telluswhat they thought we wanted to hear (i.e., there may be a social desirability bias in their responses) Whatthe multi-method study adds This synthesis of findings from the first ... to identify what works well in what contexts and why Moreover, additional research is needed to develop and evaluate tools that these organizations can use to support theuseofresearch evidence ... contributed to drafting the article RM participated in the design ofthe study, led the data collection for the second and third phases ofthe study, led the analysis ofthe qualitative data, and...
... target users Only 14% of GSUs submitted products to any form of clearinghouse More than onehalf of organizations were involved in different strategies to develop the capacity of target users to ... assess, and use their products or services Almost two-thirds of GSUs involved target users in an implementation group, whereas lower proportions of other types of organizations involved target users ... (47%) Strategies used to develop the capacity of target users to acquire, assess and use products they produce or services they deliver* Organize training workshops for target users 19 (61%) 12...
... HTAs, or both referred specifically to using 'Cochrane methods,' one noted their useof a hierarchy of outcomes, and another noted their useofthe Grading of Recommendations Assessment, Development ... products, the processes they use, and the perceived strengths and weaknesses in these processes Several organizations referred to the explicit useofresearch evidence as a strength ofthe processes, ... and for researchabout supporting theuseof reports and the implementation of their recommendations Competing interests The authors declare that they have no financial competing interests The study...
... focused on topics like: 1) theuseofresearch evidence in particular policy decisions, rather than the GSUs that may have produced theresearch evidence and supported its use [5-11]; and 2) the ... in the form of some researchers becoming policymakers themselves, which allowed them to bring to the policymaking process their knowledge ofresearch evidence and their contacts within theresearch ... support theuseofresearch evidence Implementation Science 2008, 3:53 Lavis JN, Paulsen EJ, Oxman AD, Moynihan R: Evidence-informed health policy – Survey of organizations that support theuseof research...
... copy of this Register annually at the beginning of August, thus enabling longitudinal analysis of developments on the Register Theresearch team has obtained copies of these extracts since 2002 The ... separately The impact ofthe abolition ofthe reciprocal route of entry for pharmacists from Australia and New Zealand may not become clear for a number of years, but this study shows that the number of ... whether their expectations are met, how they manage while they are in Great Britain, and whether their intention to return to their country of training (or Nor is there research into the ethical...
... is the total number of studied loci (r = or r = 3), n is the total number of alleles at the ith locus R found in the Aquitaine and the Corsican groups of populations, x ij is the frequency ofthe ... and location ofthe statistics SD ofthe Devinas population C S distribution at the locus FRPP94 for the Corsican and the Aquitaine provenances, and location ofthe statistics SD ofthe Devinas ... allele at the ith locus in the reference populak tion (chosen as the Aquitaine group of populations) and x ij is the frequency ofthe jth allele at the ith locus in a sample k from the k Aquitaine...
... TOPIC Talk aboutthe state of trading shares on Viet Nam stock exchange nowaday? - How does it influence on the economics of Viet Nam? - Topic has two part: I Talk aboutthe state of trading ... subjects: Definition The scale of Viet Nam‘s stock market The situation of Viet Nam‘s stock market today Limitation of Viet Nam‘s stock market II How does it influence on the economics of Viet Nam? ... interest rates is one of causes to decline ofthe stock market The economic analyst said that the rising interest rates will make difficult for investors to borrow money from the bank to continue...
... strictness ofthe law, meet the requirements of international economic integration Thereby helping the stock market develop towards a positive and sustainable way +About individual securities offers, the ... shares of companies offered to the public Conclusion, it is necessary to expand the scope of activities of individual securities offering +For information proclaimation: The expansion of disclosure ... disclosure of entities such as bills, it is hard to control and supervise a substance of these activities The evaluation ofthe reliability ofthe information that is hard to be corrected Therefore, the...
... about networking, they tend to think about exchanging business cards, says Hanabury Because students move through the program with the same group of students and because they often work together, ... University “Obviously most people think aboutthe financial rewards, but there is much more – what it does for their perspective, what it does for their confidence, what it does to improve their contributions ... simply based on the genius of their idea and the energy that they bring to the table to execute,” says Wilson But then they reach a point as the organization grows where the lack of experience...
... The effect ranged from 0.7% ofthe poorest household incomes (defined as less than £36 per week) to about 0.25% of median household income (£140 per week) to less than 0.1% ofthe richest household ... result of its useThe views expressed by authors or editors not necessarily represent the decisions or the stated policy ofthe World Health Organization What is known aboutthe effectiveness of ... The designations employed and the presentation ofthe material in this publication not imply the expression of any opinion whatsoever on the part ofthe World Health Organization concerning the...
... limited in their effects because ofthe inherent lags in stock turnover They become less useful for longer time frames because ofthe greater likelihood that the past experience on which the econometric ... Projections of total U.S primary energy use from the 1970s The figure is redrawn from a Department of Energy report (3) and simplified from a summary of dozens of forecasts Actual use at the end ofthe ... and then use those relationships to forecast the future These models are often used to assess the potential effects of proposed changes in government policy or business strategy The fact that these...
... consideration of a general approach to restrictions on use Thus, the Court of Justice upheld a general prohibition in Sweden on the industrial useof trichloroethylene because ofthe health and life of ... on the free movement of goods relating to theuse to which goods are put They are remarkable because they put an end to a serious controversy aboutthe scope ofwhat is now article 34 ofthe ... GOODS AND THEIR USEWHAT IS THEUSEOF IT? Laurence W Gormley* INTRODUCTION Gordon Slynn, Lord Slynn of Hadley, was an outstanding Advocate General and then judge at the Court of Justice ofthe European...
... coating and hours for cooling The thickness ofthe CVD coating is a function ofthe reaction concentration, this being the subject of: various gaseous constituents and their respective flow rates, ... to minimise the effects of thermal shock on the cutting insert, by having additions of titanium carbide added to the alumina, this causes the insert to turn black A problem with these earlier ... alloys used in the automotive industries, while not discounting the wide range of workpiece composites employed by the aerospace industries and the resin-based components utilised in the furniture...