transforming growth factor β
Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot
Ngày tải lên :
07/03/2014, 01:20
... signaling during transforming growth factor-
beta-induced smooth muscle differentiation. J Biol
Chem 281, 1765–1770.
143 Deaton RA, Su C, Valencia TG & Grant SR (2005)
Transforming growth factor- beta1-induced ... of transforming growth factor-
beta in idiopathic pulmonary fibrosis. Am J Respir Cell
Mol Biol 5, 155–162.
153 Broekelmann TJ, Limper AH, Colby TV & McDonald
JA (1991) Transforming growth factor ... & Colicelli J (2008) Integration of
transforming growth factor beta and RAS signaling
silences a RAB5 guanine nucleotide exchange factor
and enhances growth factor- directed cell migration.
Mol...
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Báo cáo khoa học: Fragile X-related protein FXR1 controls posttranscriptional suppression of lipopolysaccharide-induced tumour necrosis factor-a production by transforming growth factor-b1 doc
Ngày tải lên :
22/03/2014, 21:21
... anti-inflammatory
cytokine transforming growth factor- b1 (TGF-b1) of
the proinflammatory cytokine TNF-a via the induction
of FXR1 is the focus of this article.
TGF-b1, a member of the large transforming growth
factor- b ... post-
transcriptional suppression of lipopolysaccharide-induced
tumour necrosis factor- a production by transforming
growth factor- b1
Tarnjit K. Khera
1
, Andrew D. Dick
1,2
and Lindsay B. Nicholson
1,2
1 ... fluorescent protein; siRNA, small interfering RNA; TGF-b1, transforming
growth factor- b1; TIA-1, T-cell intracellular antigen 1; TNF-a, tumour necrosis factor- a; TTP, tristetraprolin.
2754 FEBS Journal...
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Báo cáo y học: Identification of an element within the promoter of human selenoprotein P responsive to transforming growth factor-b ppt
Ngày tải lên :
31/03/2014, 23:20
... arylhydrocarbon
receptor expression by transforming growth factor- b
1
. Mol.
Pharmacol. 59, 716 724.
22. Do
ă
hr, O. & Abel, J. (1997) Transforming growth factor- beta 1
coregulates mRNA expression ... 491]. Nature 394, 909–913.
28. Roberts, A.B. & Sporn, M.B. (1990) The transforming growth
factor- bs. In Peptide Growth Factors and Their Receptors I (Sporn,
M.B. & Roberts, A.B., eds), pp. ... (1999) Remarkable versatility
of Smad proteins in the nucleus of transforming growth factor- b
activated cells. Cytokine Growth Factor Rev. 10, 187– 199.
34. Xu, W., Angelis, K., Danielpour, D.,...
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- 1
transforming growth factor-beta protocols
Ngày tải lên :
11/04/2014, 07:14
... platelet type ` transforming growth
factor. Science 226, 705–707.
41. Kojima, S. and Rifkin, D. B. (1993) Mechanism of retinoid-induced activation of
latent transforming growth factor- ` in bovine ... the cellular receptor for transforming growth factor type `. Biochemistry 25,
3083–3091.
3. Massagué, J. (1987) Identification of receptors for type-` transforming growth
factor. Methods Enzymol. ... (1997) Transforming growth factor- ` signal-
ing in epithelial cells. Pharmacol. Ther. 75, 21.
16. Jin, G. and Howe, P. H. (1997) Regulation of clusterin gene expression by trans-
forming growth factor...
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báo cáo hóa học:" Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?" pot
Ngày tải lên :
18/06/2014, 15:20
... 0.026
BMI TGF -β1 TGF -β1 TGF -β1
rho = 0.13 rho = 0.18 rho = 0.09
P = 0.46 P = 0.22 P = 0.56
US score ND TGF -β1 TGF -β1
rho = -0.08 rho = 0.05
P = 0.57 P = 0.72
Fibrosis score TGF -β1 ND TGF -β1
rho = -0.09 ... MND, PC, FP, AR
Association between serum TGF -β1 and ferritinFigure 2
Association between serum TGF -β1 and ferritin.
TGF -β1 , transforming growth factor- beta1.
100 200 300 400 500 600 700
200
180
160
140
120
100
80
60
40
20
Ferritin ... 3: Correlations between TGF -β1 and other parameters
CHC N = 36 FL N = 45 NASH N = 42
CRP ND TGF -β1 TGF -β1
r = 0.37 r = 0.29
P = 0.08 P = 0.055
ALT TGF -β1 TGF -β1 TGF -β1
r = -0.02 r = -0.13 r = -0.34
P...
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báo cáo hóa học: " Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised" potx
Ngày tải lên :
19/06/2014, 22:20
...
Abstract
Background: The over-expression of transforming growth factor β- 1(TGF -β1 ) has been reported to cause hydrocephalus, glia
activation, and vascular amyloidβ (Aβ) deposition in mouse brains. Since ... purposes)
Background
Transforming growth factor- β1 (TGF -β1 ) is a multifunc-
tional cytokine implicated in developmental processes,
immune host defense, and injury repair [for review, [1]].
TGF -β1 contributes ... overexpressing
transforming growth factor- beta 1. Am J Pathol 1995, 147:53-67.
4. Wyss-Coray T, Lin C, Sanan DA, Mucke L, Masliah E: Chronic over-
production of transforming growth factor- beta1...
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Báo cáo y học: "Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees" potx
Ngày tải lên :
09/08/2014, 01:21
... clinical
applications of transforming growth factor- beta (TGF-beta).
Growth Factors 1993, 8:1-9.
3. Assoian RK, Komoriya A, Meyers CA, Miller DM, Sporn MB:
Transforming growth factor- beta in human ... sequence analysis of simian transforming growth
factor- beta cDNA. DNA 1987, 6:239-244.
5. Miller DA, Pelton RW, Derynck R, Moses HL: Transforming
growth factor- beta. A family of growth regulatory peptides.
Ann ... R132
Introduction
Transforming growth factor (TGF) -β is a dimeric protein of
25 kDa molecular weight, originally isolated from platelets
[1,2]. There are three distinct mammalian isoforms, TGF -β1 ,
TGF -β2 and...
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Báo cáo y học: "β Transforming growth factor-β-induced regulatory T cells referee inflammatory and autoimmune diseases" potx
Ngày tải lên :
09/08/2014, 06:22
... Oklu R, Hesketh R: The latent transforming growth factor
β
binding protein (LTBP) family. Biochem J 2000, 352:601-610.
32. Shi Y, Massagué J: Mechanisms of TGF-
β
signaling from cell
membrane ... molecular bridge
by which TGF -β on the Treg orchestrates suppression of
the responder cells [6,8,12].
TGF-
β
signaling and regulation
TGF -β is a potent cytokine and growth factor whose
biological ... = rheumatoid arthritis; SLE = systemic
lupus erythematosus; TβR = TGF -β receptor; TCR = T-cell receptor; TGF = transforming growth factor; Th = T helper cell; Treg = regulatory T
cell(s); TSP...
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Báo cáo y học: "Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity" ppsx
Ngày tải lên :
09/08/2014, 07:20
... catabolic and anabolic factors that develops with
age. IL-1 is a catabolic factor known to induce cartilage damage,
and transforming growth factor (TGF)-beta is an anabolic factor
that can counteract ... common-Smad,
Figure 2
Staining of various transforming growth factor (TGF)-beta signaling molecules in cartilageStaining of various transforming growth factor (TGF)-beta signaling
molecules in ... by three members of the transforming growth factor- beta
superfamily. J Orthop Res 1997, 15:463-467.
8. Izumi T, Scully SP, Heydemann A, Bolander ME: Transforming
growth factor beta 1 stimulates...
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Báo cáo y học: " Aging, osteoarthritis and transforming growth factor-β signaling in cartilage" pps
Ngày tải lên :
09/08/2014, 07:20
... morphogens and
growth factors and catabolic cytokines is at the crux of the problem
of osteoarthritis. One such signal is transforming growth factor- β
(TGF -β) . The impaired TGF -β signaling has ... in this journal of anabolic growth factor, trans-
forming growth factor- β (TGF -β) signaling in articular cartilage
in aging mice [2]. This commentary will discuss TGF -β
signaling and osteoarthritis ... (Drosophila melanogaster) involved as intracellular substrate
for TGF -β and BMP signaling; TGF -β = transforming growth factor- β.
Available online http://arthritis-research.com/content/8/1/101
Abstract
Osteoarthritis...
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Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx
Ngày tải lên :
09/08/2014, 08:22
... atherosclerosis.
TGF -β
1
is an inhibitor of smooth muscle and endothelial cell
proliferation [8]. Mice heterozygous for the deletion of the
TGF -β
1
gene (tgfβ
1
+/-
) have a 50% reduction in levels of TGF-
β
1 ... patients and TGF -β
1
Activation Index are correlated, using Pearson test. PBMC, peripheral blood mononuclear
cell; SLE, systemic lupus erythematosus; TGF, transforming growth factor.
Arthritis ... 7
(page number not for citation purposes)
Vol 8 No 3
Research article
Activation of transforming growth factor- β
1
and early
atherosclerosis in systemic lupus erythematosus
Michelle Jackson
1
,...
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- 0
Báo cáo y học: "Constitutive upregulation of the transforming growth factor-β pathway in rheumatoid arthritis synovial fibroblasts" doc
Ngày tải lên :
09/08/2014, 10:20
... 2
mRNA-expression of the transforming growth factor (TGF) -β related genesmRNA-expression of the transforming growth factor (TGF) -β related genes: (a) TGF -β1 , (b) TGF -β2 , (c) TGF -β3 , (d) TGF -β receptor 1 ... components of the transforming growth factor
(TGF) -β pathway in RA SFBs, with 2 hits in the top 30 regulated
pathways. The growth factor TGF -β1 , its receptor TGFBR1, the
TGF -β binding proteins ... pronounced
potency for further activation by the respective cytokines or
growth factors, for example, transforming growth factor (TGF)-
β. To enhance the significance of the array analysis, the mRNA
data...
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Báo cáo y học: "Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β/bone morphogenic protein signalling" pot
Ngày tải lên :
09/08/2014, 10:21
...
regulators insulin-like growth factor (IGF)1 and transforming growth factor (TGF) -β
[93,94]
STC1 Stanniocalcin inhibits calcium uptake and has inhibitory effect on bone growth during development ... Transforming growth factor, beta receptor I -4.915 1.049
NM_000118
A ENG Endoglin 4.131 -2.461
NM_001105
BOBACVR1 Activin A receptor, type I 3.791 -0.941
NM_003573
LTBP4 Latent transforming growth ... 1.611 1.050 RUNX2 2.07
TGF -β/ BMP inducible/target genes
AK001052
B OB FGFR1 Fibroblast growth factor receptor 1 4.234 1.993
NM_001553
A IGFBP7 Insulin-like growth factor binding protein 7 5.137...
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