... Angiogenic and angiostatic factors in systemic sclerosis: increased levels ofvascularendothelialgrowthfactor are a feature ofthe earliest disease stages and are associated with the absence of fingertip ... recognised marker of disease activity and a possible marker of disease severity [6,7,21]; the expression of adheFigure Figure factor (VEGF) concentrations residue andvascularendothelialgrowth Correlation ... activity and neutralises the effects of VEGF; it plays a pivotal role in the generation ofvascular diseases such as pre-eclampsia and intrauterine growth retardation [28] We hypothesised that the...
... Michels S, Beckendorf A, Naumann GO: Influence of photodynamic therapy on expression ofvascularendothelialgrowthfactor (VEGF), VEGF 23 receptor 3, and pigment epithelium-derived factor Invest ... understanding of its roles in each context is required to establish better therapeutic protocols leading to better prognosis List of abbreviations VEGF, vascularendothelialgrowth factor; VEGFR1, vascular ... Background: Anti -vascular endothelialgrowthfactor (VEGF) drugs and/ or photodynamic therapy (PDT) constitute current treatments targeting pathological vascular tissues in tumors and age-related...
... in epithelial andendothelial cells Permeability ofendothelial monolayer To determine the protective effect of VEGF on theendothelial cells, we measured the albumin influx into the lower chamber ... permeability and apoptosis in a single model of lung injury To evaluate theroleof VEGF in the apoptosis ofendothelial cells and their barrier function in the injured lung, we evaluated the effects of ... AM: Vascular permeability factor /vascular endothelialgrowth factor, microvascular hyperpermeability, and angiogenesis Am J Pathol 1995, 146:1029-1039 Medford AR, Millar AB: Vascular endothelial...
... P1 is the price ofthe lth category of labor services and P'i is its relative price The relative price is the ratio ofthe price ofthe lth category of labor services to the average price of labor ... where v1 is the relative share ofthe lth category of labor in the total value of labor input.3 The number of man-hours for each labor service is the product ofthe number of men, say n1, and hours ... for such a hypothesis, partly because of lack of relevant data They used the education ofthe total labor force in a state for the measurement ofthe quality ofthe labor force of individual industries...
... tyrosine kinase In theory, if they work both should block receptor activation, and thereby block the intracellular pathways Of course, direct inhibition ofthe molecules of these pathways, such ... larger series of patients About the biological role, notwithstanding the very high expression of IGF1R in GIST carrying a wild type KIT and PDGFRA status, suggesting a possible role as a therapeutic ... the effect ofthe combination with standard front line therapies [52] These analyses are particularly necessary to confirm the putative oncogenic roleof IGF1R in WT GISTs Indeed the possibility...
... improve the quality of life ofthe poor and rural people adult education programs should include as one of its components the observation and imitation ofthe artisans and other skilled persons in the ... maintains the hegemony andthe gap between the poor andthe rich, the major and minority groups In order to redress poverty the adult education program needs to be aware ofthe social functions of language ... for the betterment of their conditions It could mobilize the so called minorities to oppose their status and challenge the hegemony ofthe majority communities in Botswana 31 In most parts of the...
... transaction to the acquire and is reimbursed the amount ofthe sales ticket by the acquirer (4) - The acquirer then summits the ticket to the issuer for payment, via the ICO interchange and settlement ... maintaining the flow of funds and information between issuing and acquiring members The exchange of financial information is called clearing The exchange ofthe actual funds for the transaction andthe ... accumulation of 12 months Thegrowthof total profit showed that the Department has continuously made an effort to diversify the variety of services to meet and satisfy better customers’ needs and demands...
... “bộ” “trọn gói” theo nguyên tắc giá gói nhỏ tổng số tiền mua hàng theo phương thức riêng rẽ Định giá theo nguyên tắc địa lý: cách thức mà doanhnghiệp định giá bán sản phẩm theo nguyên tắc địa ... sản phẩm Bề rộng chủng loại sản phẩm phân giải số lượng mặt hàng thành phần theo tiêu thức định ví dụ theo kích cỡ, theo công suất… Bề rộng chủng loại sản phẩm mục tiêu công ty định phần Những ... trường theo giác độ khác Theo quan điểm Marketing thị trường bao gồm tất khách hàng tiềm ẩn có nhu cầu mong muốn cụ thể sẵn sàng có khả tham gia vào trao đổi để thoả mãn nhu cầu Như vậy, theo khái...
... 2009, and consisted of a total of 111 patients Data collection A retrospective review of clinical charts and Up to three reasons for referral as stated by the consultee were recorded, and a mean of ... (e.g., health insurance system) limit the generalization of those findings The aim of this study was to investigate the clinical characteristics of obstetric and gynecologic inpatients referred ... gynecologists using the International Classification of Diseases (ICD) ofthe World Health Organization, ninth revision The rate of psychiatric consultation in obstetric and gynecological inpatients...
... angiogenesis factorThe angiogenesis factor (vascular endothelialgrowthfactor (VEGF) is expressed in fetal but not in adult tendons [20,21] In adult tendons, the anti-angiogenesis factor endostatin ... at the wrist level The diagnosis of tendinopathy ofthe main body ofthe Achilles tendon is made if patients have Achilles tendon pain at rest or at exercise in the main body ofthe Achilles tendon, ... monitor and evaluate the volume ofthe Achilles tendon andthe mean intratendinous signal Furthermore, the same authors reported that both, eccentric and concentric loading ofthe Achilles tendon...
... detected and found to be relatively constant throughout the period ofgrowth (4-14 d) (Fig 2b) GS activity was generally higher during the initial period of rapid growth (5-10 d) and decreased thereafter ... Inhibition of GS and glutamate synthase blocked the synthesis of glutamine and glutamate, respectively When GS was inhibited, some glutamine was synthesised initially, and this may have accounted for the ... glutamine synthetase (GS) activity by the biosynthetic assay, and for NADPH and NADH-dependent GDH activity (Lea, 1985) After 17 or 18 d growth, the nitrogen-starved were transferred to flasks of fresh...
... such as the skin [2•], this review addresses mainly theroleof SLPI and elafin in the lung SLPI Gene structure, protein and antiproteinase activity SLPI is one ofthe two members ofthe ALP ... Hochstrasser et al [7] and Kramps and Klasen [8], and further characterized by us in bronchial secretions [9] and by Wiedow et al and Molhuizen et al in the skin [10,11] The sequence ofthe gene for ESI ... Marsden and Professor C Haslett, for their involvement with the published work on SLPI and elafin, and also Professor J Gauldie, Dr SC Donnelly for his help in the study of acute lung injury, and...
... as the underlying risk of mortality increased the log odds mortality under steroid treatment decreased (Table 5) The removal ofthe CSG study [32] attenuated the negative slope ofthe line In the ... quantitative evidence of smallstudy effects (at the 0.1 level) andthe number of studies was small In the presence of sparse data and moderate heterogeneity (Table 5), the interpretation of funnel plot ... (iii) the mortality OR and probability (P) that the OR was or more in the predictive distribution (that is, in the next ‘new’ study); (iv) the mortality OR for hypothesized studies of size 2,000 and...
... decision-making field of strategic management has used the concepts of uncertainty from these disciplines and applied them to the issues ofthe firm, including the existence andthe boundary ofthe firm Transaction ... owing to the difficulty of forecasting, the longer the period ofthe contract is for the supply ofthe commodity or service, the less possible, and indeed, the less desired it is for the person ... resources and capabilities affect thegrowthofthe firm andthe level of uncertainty mediates the relationship Risk and uncertainty clearly affect the amount and variety of managerial services required...
... with and without IPostC treatment 88 4.3.2. Roleof endogenous H2S in the cardioprotection induced by IPostC 90 4.3.3. Roleof endogenous H2S in the activation of PKC isoforms ... blood flow into and out ofthe heart A region ofthe heart called the sinoatrial (SA) node is capable of producing and discharging an action potential and sending the impulse across the atria to ... lysing the thrombi in the infarct artery The effectiveness of thrombolytic therapy is determined by the timing ofthe therapeutic intervention The best results are always observed when the thrombolytic...
... suitable inoculum for the pathogen and determines the severity ofthe disease However, the genetic and biochemical control ofthe onset of conidiation, andthe regulation of proper morphogenesis ... within the ATG8 locus) to remove the fragment spanning approximately last 500 bp ofthe promoter and first 72 bp ofthe coding sequence of ATG8 The resultant vector was then ligated with the PCR-amplified ... 46 the atg8∆ mutant andtheroleof autophagy and nutrient utilization was investigated during conidiation and in planta growth in Magnaporthe By genetic and biochemical studies, autophagy and...
... significantly high and low (respectively; p < 0.001) in the gph1Δ atg8Δ andthe gph1Δ, when compared to the wild type or the atg8Δ strain (Fig 5C) At the late stage of conidiogenesis, the atg8Δ andthe gph1Δ ... loss of aerial growth in the atg8Δ was highly pronounced on media containing lactose as the sole source of carbon Therefore, we tested the conidiation capability of atg8Δ in the presence of a ... suppressed with the addition of G6P or glucose (Fig 5B; p < 0.001) to thegrowth medium We conclude that the loss of Gph1 function, either through deletion of GPH1 or by inhibition ofthe enzyme activity...
... introduction of endosomal system .11 1.2.1 Classification and cellular roles of endosomes .11 1.2.2 Physiological function of endosomes .13 1.3 Magnaporthe oryzae, the rice blast ... insights and his exemplary guidance and support through out the course of this work The member of my graduate committee: Dr Gregory Jedd, Dr Mohan Balasubramanian and Dr Markus Wenk, for their useful ... Generation and characterization of an atg20∆ mutant in Magnaporthe 90 4.2.2 Subcellular localization of Atg20 .90 4.2.3 Investigation of non-selective autophagy andthe Cvt pathway in the atg20∆...
... strengthened thereafter (Chase and Dasu, 2001; Pine and Gilmore, 1998) Chase and Dasu (2001) highlight the importance ofthe sequence andthe duration, as well as the trend ofthe sequence They ... gives a description of our research methodology andofthe elaboration ofthe survey instrument Chapter consists in the presentation ofthe results ofthe statistical analysis ofthe data we collected ... on emotions and loyalty However, their definition of time elements during the service is rather vague and further research is needed to understand the impact of time and sequence of events on...