the cause of the war of spanish succession in 1701 was

The Female Brain is one of the most-talked-about books of the year. ppt

... obsessed about scoring in games, and in the backseat of a car. At the point when boys and girls begin deciding the trajectories of their careers, girls start to lose interest in pursuits that ... response. The girls will think that if they do it just right, they’ll get the reaction they expect. It’s the same kind of instinct that keeps a grown woman going after a narcissistic or other-wise ... to the brain, and the brain does all the interpreting. A good conk on the head in the right place can mean that you won’t be able to smell or taste. But the brain does more than that. It profoundly...

Báo cáo khoa học: Interaction of the E2 and E3 components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus ppt

Danh mục: Báo cáo khoa học

... 119–171) of the B. stearothermophilusE2p polypeptide chain with the dimer of a proteindomain (E3int) representing the interface domain (resi-dues 343–470) of B. stearothermophilus E3. The use of the ... domains, followed by a peri-pheral subunit-binding domain (PSBD) responsible forbinding E3 in the majority of organisms. In icosahe-dral complexes, the PSBD is also involved in the bind-ing of ... close to the twofold axis of E3preventing the association of a second PSBD [28,29]. The interaction occurs at the C2-axis of symmetry in the E3 dimer, chieﬂy with the interface domain of E3,which...

Tài liệu THE HISTORY OF THE RISE, PROGRESS, AND ACCOMPLISHMENT OF THE ABOLITION OF THE SLAVE-TRADE pdf

Danh mục: Du lịch

... this uneasiness continued till he was assured that the introduction of them in this capacity into his foreign dominions was the readiest way of converting them to the principles of the Christian ... examining it in three points of view. First, as it has been proved to arise on the Continent of Africa, in the course of reducing the inhabitants of it to slavery. Secondly, in the course of ... presume the reader will not be a little interested and entertained, in viewing with me the course of the abolition of the Slave Trade, in first finding its source, and then in tracing the different...

Tài liệu Đề tài " Asymptotic faithfulness of the quantum SU(n) representations of the mapping class groups " pdf

Danh mục: Thạc sĩ - Cao học

... consequence of Corollary 1. In this paper we have initiated the program of using of the theory of Toeplitz operators on the moduli spaces in the study of TQFT’s. The maininsight behind the program is the ... get that the norm of the Reshetikhin-Turaev quan-tum invariant for all k and n =2(n = 3 in the genus 2 case) can separate the mapping torus of the identity from the rest of the mapping tori ... invariants, resulting in interesting topological conclusions, including very strong knot theoreticalcorollaries. Writeup of these further developments is in progress.It is also an interesting...

Tài liệu Báo cáo khoa học: Characterization of the interaction between the plasma membrane H+-ATPase of Arabidopsis thaliana and a novel interactor (PPI1) doc

Danh mục: Báo cáo khoa học

... or byFC-induced binding of 14-3-3s.Results The C-terminus of isoform 1 of the PM H+-ATPase of A. thaliana (AHA1) interacts with the ﬁrst 88 aminoacids of PPI1 [22], indicating that the PM ... suggested by the parallel increase of the number of FC-bindingsites [18–20]. As to auxin, a soluble auxin receptor hasbeen reported to bind and activate the PM H+-ATPase,but the site of binding has ... fusion protein, containing the PPI1 protein devoid only of the last 24 aminoacids, a putative transmembrane domain (PPI1588His6); the His-tag was fused to the protein C-terminus, tominimize...

Tài liệu proceedings of the 5th ph d retreat of the hpi research school 5 ppt

Danh mục: Kỹ thuật lập trình

...

BURN THE FAT FEED THE MUSCLE Fat Burning Secrets of the World’s Best Bodybuilders & Fitness Models pdf

Danh mục: Sức khỏe giới tính

... powerful fat burning principles on Earth. The proof as they say, is in the pudding! Be patient in the beginning – all the information in the early chapters will come together in the end It ... mind has two components: The conscious and the subconscious. The conscious mind is the rational, logical, analytical, thinking part of the mind. The conscious mind is constantly taking in information ... visualization in many ways: they visualize their workouts or they see themselves successfully completing a lift or performing aerobic training. They also see pictures of their bodies the way they want them...

Báo cáo khoa học: Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein pptx

Danh mục: Báo cáo khoa học

... peptides, other regions of the Gag protein, or even other proteins). In the ﬁrstthree examples, the second helix (as in CACW40A) was the main element of secondary structure affected; in the last ... depositedstructure: the ﬁrst a-helix is in blue; the second one in green; and the last a-helix is shown in yellow. The single turn of a 310-helix at the N-terminus of the protein is shown in red.Dynamics of ... vectorsare independent of the overall rotational movement of the molecule). Furthermore, the internal motions of each bond vector are independent of each other, but the rotational diffusion of the molecule...

Báo cáo khóa học: Disruption of the interaction between the Rieske iron–sulfur protein and cytochrome b in the yeast bc1 complex owing to a human disease-associated mutation within cytochrome b potx

Danh mục: Báo cáo khoa học

... discussed in greater detail below.Instability of the mutant enzymeFurther analysis of the kinetic parameters of the G167Emutant was hindered by rapid inhibition of the activity of the bc1complex ... substrateand the inherent partioning of quinol into the Qosite. The Fig. 3. Steady-state level of the iron–sulfur protein (ISP) in G167E.Immunoblots of denaturing gels, loaded with 40 lg of protein ... unstableunder the conditions of the assay. This was conﬁrmed bymonitoring the sensitivity of the activity of the bc1complexto detergent. The mutant enzyme was inactivated by a 2 minincubation...

Báo cáo khoa học: Solution structure of the active-centre mutant I14A of the histidinecontaining phosphocarrier protein from Staphylococcus carnosus ppt

Danh mục: Báo cáo khoa học

... Ala19. In addition, the C-terminusfolds back onto the core of the protein thereby allowing the side chain of Leu86 to partly ﬁll the hole created by the removal of Ile14. Due to these changes other ... into the active-centre loop. They lead to a dis-placement of the ring system of His15 and a distortion of the N-terminus of the ﬁrst helix, which supports the histidinering. In ad dition, the ... The replacement of I le14 by Ala causes a slightlongitudinal compression of the mutant protein (Fig. 4). Atits N-terminal end, helix a displays a kink towards the interior of the protein. The...

Adventurers of the Far North A Chronicle of the Frozen Seas doc

Danh mục: Khoa học xã hội

... wereoff again, the river winding and turning in its course but heading for the north-west. Here and there on the banks they saw traces of the Eskimos, the marks of camp fires, and the remains of ... Franklin did the best he {98}could; he read to them the creed of the Church of England in French. In the leisure part of the day a bundle of London newspapers was perused again and again. The winter ... made in the middle of the night, but at this season of the year the whole {60} scene was brilliant with the light of the midnight sun. The Indians stole to within twohundred yards of the place indicated...

Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot

Danh mục: Báo cáo khoa học

... [38,39], the enzymes involved in APLP1 ectodomain cleavage areless well deﬁned [40,41]. Irrespective of the identity of the enzymes involved, ectodomain shedding of APP,APLP1 and APLP2 results in the ... produc-tion of ICDs for all three proteins was not decreased by loss of BACE1activity. These results indicate that BACE1 is involved in regulating ecto-domain shedding, maturation and trafﬁcking of the ... r.p.m. The resulting suspen-sion was then centrifuged at 175 000 g and 4 °C for 30 min,and the upper 75% of the supernatant was collected. Proteincontent was assessed using a bicinchoninic acid...

Báo cáo khoa học: Structure–function analysis of the ﬁlamentous actin binding domain of the neuronal scaffolding protein spinophilin pot

Danh mục: Báo cáo khoa học

... studies of the actin binding domain of spinophilin. We demonstrate that the spinophilinactin binding domain is intrinsically unstructured, and that, with increasingC-terminal length, the domain ... of the spinophilin constructs, as this has beenshown to shift the activity of other proteins betweenF-actin bundling and crosslinking [39].Spinophilin is a pointed-end capping protein In the ... highdegree of disorder in the ABDs of spinophilin andneurabin. On the basis of these analyses, spinophilinand neurabin ABDs were predicted to be intrinsicallyunstructured proteins (IUPs).Spinophilin...

Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot

Danh mục: Báo cáo khoa học

... result-ing in a chimeric protein designated gp130c.Inordertoinvestigate the role of the membrane-proximal domains of gp130 in receptor activation, the FNIII-domain deletionswere introduced into the ... domain in the membrane-proximal part of gp130leads to a shift of the receptor areas involved in ligandbinding closer to the membrane, resulting in the inability of the receptor chains to form ... membrane-proximaldomains of gp130 is limited to ensure the correct spacingbetween the CBM and the membrane, each of the domains was replaced by the corresponding domain of the GCSFR. The replacement...