... conditions C
1
–C
3
in Theorem 4.2 are satisfied for the
above specified functions and parameters. Therefore, in the light of Theorem 4.2, we conclude
that the dynamic equation on the specified time ... types of time scales 3–11. On the other hand, along
with the significant development ofthe theories, practical applications of dynamic equations
on time scales in mathematical modeling of those ... light ofthe five functionals fixed point theorem, they established thecriteriafor the
existence of at least three solutions forthe dynamic equation 1.1 either with conditions
1.4 or with conditions...
...
for developing new products for a company, whether it is
an upgrade of an existing product or a new concept
(either forthe company or forthe customer). It includes
all activities from the ... collaboration, led by the
project manager, the information for production of a new
product will be integrated, and the project will be finished
in real time. Furthermore, the cost for production ...
feedback, the purpose ofthe conceptual model, some background
of the research that lead to the development ofthe model, and key
11852 Afr. J. Bus. Manage.
Figure 5. Trend of project...
...
togetherwithanexamination of keyuncertaintiesandlimitations;andaseries of
conclusionsandinsightsgainedfrom the analysis.ItisimportanttorecallthatthisRIA
restson the analysisdonein2008;nonewairqualitymodelingorotherassessments
werecompletedexceptthoseoutlinedabove.
The supplementincludesapresentation ofthe benefitsandcosts of attainingvarious
alternativeozoneNationalAmbientAirQualityStandardsin the year2020.Theseestimates
onlyincludeareasassumedtomeet the currentstandardby2020.Theydonotinclude the
costsorbenefits of attaining the alternatestandardsin the SanJoaquinValleyandSouthCoast
airbasinsinCalifornia,becauseweexpectthatnonattainmentdesignationsunder the CleanAir
Act for theseareaswouldplacethemincategoriesaffordedextratimebeyond2020toattain
the ozoneNAAQS.
InTableS1.1below, the individualrowestimatesreflect the differentstudiesavailableto
describe the relationship of ozoneexposuretoprematuremortality.Thesemonetizedbenefits
includereducedhealtheffectsfromreducedexposuretoozone,reducedhealtheffectsfrom
reducedexposuretoPM
2.5
,andimprovementsinvisibility. The rangeswithineachrowreflect
twoPMmortalitystudies(i.e.PopeandLaden).
Rangesin the totalcostscolumnreflectdifferentassumptionsabout the extrapolation
of costsasdiscussedinChapter5 ofthe 2008OzoneNAAQSRIA. The lowend ofthe range of
netbenefitsisconstructedbysubtracting the highestcostfrom the lowestbenefit,while the
highend ofthe rangeisconstructedbysubtracting the lowestcostfrom the highestbenefit.
The presentation ofthe netbenefitestimatesrepresents the widestpossiblerangefromthis
analysis.
TableS1.2presents the estimate of totalozoneandPM
2.5
‐relatedprematuremortalities
andmorbiditiesavoidednationwidein2020asaresult of thisregulation.
S2‐2
rate of ozonereductionseeninpreviousairqualitymodelingexercisestoestimate the
additionalemissionsreductionsneededtomeet the lowertargets. The details ofthe
approachareexplainedbelow,but for mostareas ofthe analysisweusedsimpleimpact
ratiostoproject the ozoneimprovementsasarate of NOxemissionsreduced.Use of
non‐site‐specific,linearimpactratiostodetermine the non‐linear,spatially‐varying,
ozoneresponsewasanecessarylimitationwhichresultsinconsiderableuncertaintyin
the extrapolatedairqualitytargets.
... The costs of identifiedcontrolmeasuresaccounts for anincreasinglysmallerquantity of
the totalcosts of attainment.Thisisamajorlimitation ofthe costanalysis.Weassume
amajority ofthe costs of attaining the tighteralternativestandardswillbeincurred
throughtechnologieswedonotyetknowabout.Thereforecostingfutureattainment
baseduponunspecifiedemissionreductionsisinherentlydifficultandspeculative.
The uncertaintiesandlimitationssummarizedabovearegenerallymoreextensivethan
those forthe 0.075ppm,0.070ppm,and0.065ppmanalyses. The tablebelowcontrastsour
level of confidenceineach ofthe keyresults.
TableS2.1:Keyuncertaintiesandlimitationsin the analysis for
0.060ppmand0.055ppm
Analyticalquestion ... TableS2.9presentsa summaryofthe totalnationalcosts of attaining the 0.055ppm
and the 0.060ppmalternativestandardsin2020.This summary includes the engineeringcosts
of the modeledcontrolstrategy(presentedin the 2008OzoneNAAQSRIAChapter5
4
), the
additionalsupplementalcontrols,aswellas the extrapolatedcosts.ConsistentwithOMB
CircularA‐4,costsarepresentedata7%discountrate.
7
The midrangeestimateconsists of usinganMvalue of 0.24 forthe estimation ofthe averagecostperton of
controlbygeographicarea. For acompletelisting of averagecostpertonbygeographicareaseeAppendixS2a.
S2‐10
FigureS2.2:Map of ExtrapolatedCostCounties forthe 0.060ppmAlternateStandardand
EstimatedPercentageNOxControlsNeededtoMeetthatStandardin2020
S2.3...
... respect of either the evaluation ofthe extent of the
protection afforded to any given mark or the recognition of service marks.
(2) Each ofthe countries ofthe Special Union reserves the right ... with the Office of origin. In
the event of disagreement between the said Office and the International Bureau, the opinion of the
latter shall prevail.
Article 4
Effects of International Registration
(1)(a) ... to registrations of marks the numbers ofthe classes of the
Classification to which the goods or services for which the mark is registered belong.
(4) The fact that a term is included in the...
... country of
the Special Union.
Article 13
Reference to Article 24 ofthe Paris Convention
The provisions of Article 24 ofthe Stockholm Act of 1967 ofthe Paris Convention
for the Protection of ...
Recordal of Change in the Ownership of an International Registration
At the request ofthe person in whose name the international registration stands, or at the
request of an interested Office ... decided upon by the Committee of Experts and recommendations ofthe
Committee of Experts shall be notified to the competent Offices ofthe countries ofthe
Special Union by the International...
... of
adipogenic differentiatedhMSCs,alsointhecorner
area s ofthe micro cavity (Figure 3f). The performed stu-
dies verify the biocompatibility ofthe Si
3
N
4
membrane
and the suitability ofthe ... disease, forthe develop-
ment of new sensitive drug screening methods and for
the quantification of toxicodynamic and toxicokinetic
effects.
Application ofthe MCC forthe analysis of nanoparticle-
induced ... any
subjective choice of representative areas ofthe cell
monolayer.
Besides the advantage of convenient handling, the
microscopic analysis ofsmall amounts of cells and
nanomaterials increase the through-put...
... on the prevalence in the
population, and more reflective ofthe test itself, lessening the impact of any unique features of
the VA population. Moreover, we might expect that the PPV and NPV of ... contrast to other RA therapies where
the drugs are typically discontinued if they are not effective. Because of similarities in both the
descriptive characteristics ofthe study populations of biologic ... claims
data.
To test the performance ofthe effectiveness algorithm and to see whether it was similar for
non-biologic RA treatments, we performed a separate analysis of RA patients enrolled...
... (SPN),
the experience with the management of disseminated
disease is very limited in the literature
6
, therefore,
attention to the therapy strategy of this neoplasm in
the future may allow a ... result in the uncertainty ofthe
strategy for its treatment. While further delineati n g
the clinicopathological and radiological features, and
summarizing the surgical therapy strategy of this ... damaging of CBD and PD in 8 patients. For
the patient in whom the CBD and PD were dilated,
local enucleation was firstly completed with the pre-
servation ofthe intact CBD, whereas the pancreatic...
... considering
the endoscopic option. The facet injections in these 72
patients gave 50 to 100% relief of their pain in 86% of
the patients with a median relief period of 3 months.
The range of relief ... the direct visualization
of the joint allows better de-innervation ofthe joint
and removal ofthe entire end-plate receptors that
adhere to the bone and capsular tissue.
Limitations ofthe ... considering the endoscopic surgery option. Of
these 26 patients, 14 patients had 50 to 100% relief
with a median period of pain relief being 5 months.
The range of relief forthe radiofrequency...
... laminoforaminoplasty forthe treatment of thoracic
radiculopathy: report of 12 cases
Scott M.W. Haufe
1,2
, Ryan A. Baker
3
and Morgan L. Pyne
3
1. Chief of Pain Medicine and Anesthesiology ... quality of life. Conservative therapy is the initial
treatment of choice, but fails to provide relief in a
substantial number of patients. Central and foraminal
stenosis with entrapment of descending ... or foraminal stenosis treated with endoscopic
laminoforaminoplasty via a small incision, of less than
one inch.
Materials and Methods
Twelve patients were treated with endoscopic
laminoforaminoplasty...
... in the distal seg-
ment ofthe tubule.
Inhibition of glucose reabsorption in the kidney,
mediated by the SGLT cotransport system, represents
a promising therapeutic target forthe control of ... glucose levels. For that purpose either
insulin or hypoglycemic agents have been used as
standard therapeutic agents forthe treatment of dia-
betes [7]. The mechanism of action ofthe anti-diabetic ... preventing the adverse complica-
tions of glucose toxicity observed in diabetes. The re-
sults ofthe present study suggest that some thioglyco-
sides have a therapeutic potential forthe control of...
... according to whether the patients had prior revascularization. The boundaries ofthe box are Tukey’s
hinges. The median is identified by the line inside the box. The length ofthe box is the interquartile ... measured by the MCG device. The
resulting mathematically integrated patterns ofthe
abnormal indexes are then compared for their degree
of abnormality to the abnormal index patterns in the
reference ... in-
cluded in the meta-analysis. The boundaries ofthe box are Tukey’s hinges. The median is identified by the line inside the box.
The length ofthe box is the interquartile range (IQR) computed...
... evaluating the store in
terms ofthe factors comprising the choice criteria. Based on the evaluation, the consumer
18
and figure 4.3). For each attribute of supermarkets, the score assessed by the heavy-users
were ... Curiosity ofthe new and modern western kind of store is the
main reason to pull the non-users into supermarkets, while the heavy ones go there mainly
for buying everyday necessities, for what the ... Once per two week was the most frequent trip which counted for
more than one-quarter ofthe sample. The shopping frequency of 2, 3 or 4 times was less than
20% ofthe sample for each. It was rarely...