role of school and teachers in shaping ones personality
Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
Ngày tải lên :
19/02/2014, 13:20
... of
fosfomycin binding to the K22V and K22E mutant proteins.
However, two other positively charged amino acid side
chains, R397 and R120, are also involved in fosfomycin
binding, and in view of ... fosfomycin binding due to charge–charge
repulsions. Most interestingly, the uncharged valine side
chain completely abolishes fosfomycin binding in the
absence of UDPNAG. Clearly, UDPNAG binding creates
additional ... UDP-N-acetylmuramic acid) (A) and inactivation mechanism of MurA by
fosfomycin as a result of the covalent linkage between Cys115 of MurA and fosfomycin (B).
Ó FEBS 2004 Lysine 22 and arginine 120 in MurA (Eur....
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Tài liệu Báo cáo khoa học: Role of cleavage and shedding in human thyrotropin receptor function and trafficking pdf
Ngày tải lên :
21/02/2014, 00:20
... periods of times (0–60 min)
at 37 °C. The concentration of the biotinylated Ig remaining
on the cell surface was then quantified by measuring the
binding of [
125
I]Streptavidin. In the absence of ... image.
Ó FEBS 2003 Role of cleavage and shedding in TSHR function (Eur. J. Biochem. 270) 3491
Role of cleavage and shedding in human thyrotropin receptor function
and trafficking
Myle
`
ne Quellari
1
, ... five amino acids of the
extracellular domain and devoid of any tag was not
functional [27], while a mutant containing four amino acids
of the ectodomain and including a rhodopsine tag was
found...
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Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt
Ngày tải lên :
07/03/2014, 04:20
... buffer A in 15 min, followed by a linear
gradient down to 5% buffer A in 2 min. 5% buffer A was
held for an additional 2 min and followed by a linear
gradient up to 95% buffer A in 6 min.
Determination ... °C: loading 5% buffer B, after
5 min linear gradient up to 95% buffer B in 37 min, and
then holding 100% buffer B for 5 min. The product was
identified by UV detection at 215 nm and by on-line
ESI-MS ... domain is one of the
few ACPs in which valine replaces isoleucine (I) or
leucine (L) in the conserved sequence. To determine
whether DptF is the putative partner of DptE, we
expressed dptF using...
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The Role of Savings and Wealth in Reducing ―Wilt‖ between Expectations and College Attendance pdf
Ngày tải lên :
15/03/2014, 10:20
... accumulating school savings may have effects apart from financing
school.
Conley (2001) finds that a doubling of net worth results in an 8.3% increase in the probability of
attending college. ... important for explaining
wilt. In the case of income, youth living in low-income households experience higher levels of wilt
(45%) than youth living in either modest-income (35%) or high-income (23%) ... NIVERSITY IN S T . L OUIS
10
contrast, only 20% of youth who have an account, and 26% of youth with savings designated for
school experience wilt.
The Role of Savings and Wealth in Reducing Wilt...
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Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
Ngày tải lên :
18/02/2014, 16:20
... targeting of
CYP2E1
The role of PKA in mitochondrial targeting of
CYP2E1 was investigated using two approaches. The
first approach involved measuring the level of mito-
chondrial targeting of wild-type ... University of Pennsylvania. Journal compilation ª 2007 FEBS
Mitochondrial targeting of intact CYP2B1 and CYP2E1 and
N-terminal truncated CYP1A1 proteins in Saccharomyces
cerevisiae
)
role of protein kinase ... were initiated by the
addition of 3 mm NADPH, and incubation was continued
for 30 min at 37 °C in a shaking water bath. The reactions
were terminated by adding 2 mL of ice-cold methanol, and
insoluble...
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Tài liệu Báo cáo khoa học: Unfolding of human proinsulin Intermediates and possible role of its C-peptide in folding/unfolding pptx
Ngày tải lên :
19/02/2014, 12:20
... double-chain
insulin is synthesized in vivo as a single-chain precursor
(preproinsulin) and folded as proinsulin, in which a
connecting peptide of 35 residues links the C terminus of
the B chain and ... C-peptide in the folding/unfolding of HPI (Eur. J. Biochem. 271) 1739
Unfolding of human proinsulin
Intermediates and possible role of its C-peptide in folding/unfolding
Cheng-Yin Min, Zhi-Song Qiao and ... character-
ization of the unfolding of insulin and proinsulin using the
reductive unfolding method has not been thoroughly
investigated. We have characterized the unfolding process
of an artificial porcine insulin...
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Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx
Ngày tải lên :
19/02/2014, 16:20
... that the N-terminal domain is involved in
protein–protein interactions with other hydrophilic domains
of neighboring integral membrane subunits, and interspecies
interactions are incompatible.
From ... [15–18]. In the
bovine complex a large subdomain is made up of 20
integral membrane proteins contributing > 60 transmem-
brane segments. Some of these must be intimately involved
in proton pumping. ... composition of complex I from
bovine heart has revealed the existence of two additional
subunits (bringing the total to 46), and one of these, the
ESSS protein, is also encoded by an X-linked g ene in
humans...
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Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
Ngày tải lên :
19/02/2014, 16:20
... B. (1994) The pteridine b inding site of brain nitric oxide
synthase. Tetrahydrobiopterin binding k inetics, specificity, and
allosteric interaction w ith the substrate d omain. J. Biol. Chem.
269, ... reflect ring opening of an epoxide inter-
mediate at either of its two C-O bonds [219,220].
The sum of these findings strongly invokes the notion
of oxygen activation during redox cycling of the ... nsertion
of oxygen into the benzene ring of aniline to yield
p-aminophenol [151]. Formation o f the oxygenating
species has been recognized to be fac ilitated by the b inding
to HbO
2
of aniline and...
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Tài liệu The Role of Public Regional Universities in Community and Economic Development doc
Ngày tải lên :
21/02/2014, 01:20
... University
Regional Learning Alliance – workforce development and
training/collaborations with business and industry; meeting the
training and education needs of businesses within 60 mile radius
in Northern ... Programs
and Initiatives
Business accelerators and/ or entrepreneurial initiatives
Linking teaching and research to business opportunities
Collaboration with local business and industry
Small Business ... opportunities of quality
and substance
Stimulate intellectual growth and individual productive
capacity
Ensure a stable supply of knowledge and skills in high
need areas
Increase the size, diversity of...
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HUMAN PERFORMANCE: Role of General Mental Ability in Industrial, Work, and Organizational Psychology docx
Ngày tải lên :
06/03/2014, 05:20
... Factor
Processing information (perceiving, retrieving,
manipulating, transmitting)
Compiling information, importance of 0.90 Seeing (DOT) 0.66 Work with complex things
Combining information, importance of ... use the very language of information processing, such as compiling
and combining information. Some of the most highly correlated mental demands,
such as reasoning and analyzing, are known as prototypical ... amount of 0.83 Catering and serving, importance of 0.61 Catering to people
Decision making, level of 0.82 Entertaining, importance of 0.59 Catering to people
Negotiating, importance of 0.79 Non-job-required...
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The Role of Small and Large Businesses in Economic Development doc
Ngày tải lên :
06/03/2014, 19:20
... growth from the second quarter of 2000 into job
classes using beginning size of firm, mean size of firm over the period,
and end size of firm. If the beginning size of the firm is used to classify
firms, ...
enterprises with tax breaks, financial incentives, and other induce-
ments. Instead, they are relying on building businesses from the ground
up and supporting the growth of existing enterprises. This ... efficient at innovation. Small firms
are the great innovators in some industries, while large firms are the
great innovators in others. Moreover, small and large businesses interact
in innovative...
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Báo cáo khoa học: The role of interface framework residues in determining antibody VH ⁄ VL interaction strength and antigen-binding affinity pptx
Ngày tải lên :
07/03/2014, 12:20
... antigen-binding affinity
and the V
H
⁄ V
L
interaction strength determined, five
clones in the H39Q group showed both high antigen-
binding affinity and strong V
H
⁄ V
L
interaction. In
Table 1. Result of ... enhancement in V
H
⁄ V
L
interaction signifi-
cantly improved the antigen-binding affinity of Fv,
similarly to the level of scFv (Table 2).
Some single V
H
domains of anti-protein IgG, inclu-
ding HyHEL-10 ... analysis of antigen-binding affinity
For the quantitative evaluation of the H39 mutation,
kinetic analysis for antigen–Fv interaction of the
wild-type and H39KQ mutant of purified Fv and scFv
proteins...
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