role of glial cells in the nervous system
Báo cáo khoa học: Alternative initiation of transcription of the humanpresenilin 1gene in SH-SY5Y and SK-N-SH cells The role of Ets factors in the regulation ofpresenilin 1 pptx
Ngày tải lên :
16/03/2014, 18:20
... using the c oncen tration of protein in the extract as an
internal standard. The activity of ()119/+178) PS1CAT in the pres-
ence of the empty vector was taken as 100%. The values represented in
the ... domain. ERM contains two DNA binding
inhibitory domains flanking the Ets domain: the central 87
amino acid inhibitory domain is poorly conserved a nd
virtually specific to ERM, and the C-terminal ... sequenced.
Cloning of ERM
Two independent clones containing the entire ERM cDNA
were obtained by yeast one-hybrid screening of a human
brain cDNA library from Clontech [26]. The cDNA was
then inserted into...
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Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China
Ngày tải lên :
18/10/2013, 07:15
... source of financing for enterprises, if their own
capital is excluded.
In summary, the deepening process of the financial markets has rendered the
dominance of the banking sector in the financial system. ... under the framework of financial globalization.
II. Review of Institution Building in the Financial Sector
A. Main driving forces of institution building
A review of the developments of China’s financial ... performance.
2. Role of the central bank
The central bank has played a role of policy designing and implementation in the
process of institution building in the financial sector. The promulgation of The...
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Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx
Ngày tải lên :
14/02/2014, 18:20
... USA). Binding of all of the anti-
bodies was detected using an ECL detection system (iNtRON
Biotechnology, Seoul, Korea) in accordance with the manu-
facturer’s instructions. The intensity of the ... sample buffer. The samples were then
analyzed by western blotting using the polyclonal anti-phos-
phoserine ⁄ threonine serum (Abcam) as the primary anti-
body. Binding of all of the antibodies ... injury, including endotox-
emia and ischemia ⁄ reperfusion injury [14]. In our
studies, we employed GdCl
3
to inactivate KCs based
on the findings of other investigators showing the
destruction of...
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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
Ngày tải lên :
15/02/2014, 13:20
... (
39
).
The renewed interest in examining the indications for BCG vaccination in the
United States included consideration of the wide range of vaccine efficacies deter-
mined by clinical trials ... to
explore the sources of the heterogeneity in the efficacy of the BCG vaccine reported in
the individual studies. Using a model that included the geographic latitude of the
study site and the data ... <5 mm induration
after skin testing with 5 TU of PPD tuberculin. The Tice strain of BCG is administered
percutaneously; 0.3 mL of the reconstituted vaccine is usually placed on the skin in the
lower...
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Tài liệu The Role of Community Banks in the U.S. Economy pdf
Ngày tải lên :
16/02/2014, 11:20
... an important role in the financial system of
the U.S. economy. They complement the role of large banks by special-
izing in relationship banking and providing credit to small
businesses—a sector ... understanding issues facing community banks.
I. THE CURRENT ROLE OF COMMUNITY BANKS
The banking system in the United States has always been unique in
the sense of containing large numbers of small ... understanding of business conditions in the communities
they serve. In this way, the bifurcated banking system has served the
needs of a diverse U.S. economy composed of businesses of all shapes
and...
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Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
Ngày tải lên :
18/02/2014, 08:20
... 3T3-L1 cells
were cultured in DMEM containing 10% fetal bovine
serum. OP9 cells were grown in aMEM containing 20%
fetal bovine serum. C2C12 cells were maintained in DMEM
containing 10% fetal bovine ... or without hematoxylin staining.
In hypoxia experiments, 3T3-L1 cells were maintained in
a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati,
OH, USA) constantly maintained at 1% O
2
. Culture
medium ... lgÆmL
)1
insulin, 1 lm dexamethasone, and
0.5 mm IDM). Cells were then maintained in DMEM con-
taining 10% fetal bovine serum and 1 lgÆmL
)1
insulin. The
medium was replaced every other day....
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Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx
Ngày tải lên :
19/02/2014, 06:20
... detected at the dimer
interface of the models or in the surroundings of the
mutated residues. The models of RNase A covalent dimers
in the exchanging conformation were prepared using the
7RSA structure ... at
the dimer interface of the models or in the surroundings of
the hinge loop residues. Likewise, the models of nonex-
changing and exchanging HHP-RNase were prepared start-
ing from 1Z7X. The ... and the
z axis was perpendicular to the center of the membrane
(Fig. 4);
(b) the major axis of the dimeric RNase was made coinci-
dent with the z axis of the system, hence orthogonal to the
membrane...
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Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
Ngày tải lên :
19/02/2014, 17:20
... N-linked oligosaccharide side-chains
are important for the GABA transport activity.
1-Deoxymannojirimycin inhibits the GABA-uptake
of GAT1
In order to gain further insight into the role of the
terminal ... results in reduction
of the stability of GAT1
In order to study the in uence of the N-glycosylation
and N-linked oligosaccharides on protein stability, the
intracellular decay time of the GAT1, ... for the stability of this protein,
but the terminal structure of the N-glycans is not.
Defective N-glycosylation reduces the trafficking
of GAT1 to the plasma membrane
In order to study the in uence...
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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
Ngày tải lên :
07/03/2014, 14:20
... However, the mechanistic roles of several of
these residues are not described well and there is no example
of mutational analysis of all of these residues in the same
enzyme.
To obtain an insight into ... by
the surrounding residues. The results so far indicate that
larger parts of the polar core of the catalytic TIM barrel of
family 18 chitinases play a role during catalysis. It will thus
be interesting ... conformations. The Asp142 equiv-
alent in the family 18 chitinase from Coccidioides immitis
was found to be in the ÔdownÕ position in the apoenzyme
and in the ÔupÕ position in the complex with allosamidin...
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Báo cáo khoa học: Leishmania donovani methionine adenosyltransferase Role of cysteine residues in the recombinant enzyme pptx
Ngày tải lên :
08/03/2014, 08:20
... to
determine the functional role of the amino acid residues
involved in each. The present report describes the cloning
and subsequent functional refolding, using a bacterial
expression system, of the ... a donor of propylamine
groups in the metabolism of spermidine and spermine [2]
and an intermediary in the trans-sulfuration pathway to
cysteine, one of the three amino acids involved in glutathi-
one ... domain of each
subunit, in the interface between the two dimers compri-
sing the tetrameric structure [29]. This domain contains
five cysteine residues, two of them (Cys35 and Cys61)
forming a...
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The Role of Rainfed Agriculture in the Future of Global Food Production doc
Ngày tải lên :
09/03/2014, 00:20
... trees. The largest plant height was obtained using linings of stone and
marble. During the first year of the study, when the lining served only as mulch due to
lack of rainfall, an increase of ... to improve the HI of wheat,
9
The harvest index is defined as the ratio of grain to total crop biomass” (Cassman 1999).
The Role of Rainfed Agriculture in the Future of
Global Food Production ... important in the initial decision of whether to
adopt rainwater harvesting at an individual farm level. Especially due to the low economic
status of many of the farmers in regions where rainwater...
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The Role of Bank Capital in the Propagation of Shocks potx
Ngày tải lên :
15/03/2014, 10:20
... to the banking sector
The previous subsection analyzes how the banking sector, through the dynamics of bank
capital, affects the transmission of shocks. In recent years, however, episodes of increased
volatility ... to them.
In this context, this subsection considers the effects of a shock that arises in the banking
sector of our model and leads to exogenous declines in bank net worth. Following the
theoretical ... households investing in the
bank is limited by the two moral hazard problems: if either were to worsen, the payment
to households would decrease.
Introducing (19) into the participation constraint (14),...
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Báo cáo khoa học: Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus – the role of conserved residues in the active site pdf
Ngày tải lên :
15/03/2014, 11:20
... number
of amino acid residues contribute to the binding of the
substrate by hydrogen bonding and ⁄ or hydrophobic
interactions. Using the ligplot program [31], we
investigated the specific interactions ... 2010)
doi:10.1111/j.1742-4658.2010.07685.x
The hyperthermostable chitinase from the hyperthermophilic archaeon
Pyrococcus furiosus has a unique multidomain structure containing two chi-
tin-binding domains and two catalytic domains, ... identical, but the D524A mutation resulted in a
remarkable change in the conformation of the Glu526
side-chain. The 2F
obs
) F
calc
electron density of the
Glu526 side-chain in the D524A–substrate...
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THE ROLE OF BIODIVERSITY CONSERVATION IN THE TRANSITION TO RURAL SUSTAINABILITY pptx
Ngày tải lên :
15/03/2014, 18:20
... Policy
for the
United
States
Dramatic changes
in the
landscape
of
farming
have unwittingly contributed
to
hypoxia
in the
Gulf.
The
increased nitrate loading
to the
Gulf
of the
past
... from
the
environment begin
to
influence
the
periphery
of the
system faster than
the
central decision-making
can
respond, then things
Figure
2.
Systems
view
of
decision
making
start
... action
in the
North.
Such
an
agenda will
be
aimed
at
achieving real
progress
on
sustainability.
The
intent
in
organizing
the
NATO
ARW was to
bring
together
a
range
of
disciplinary...
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Environmental Injustice and Human Rights Abuse: The States, MNCs, and Repression of Minority Groups in the World System pptx
Ngày tải lên :
15/03/2014, 23:20
... are: the murder of
Wilson Pinheiro and Francisco “Chico” Mendes in the
Amazon rain forest, the massacre of Father Nery Lito Satur
and several others in the Philippines, and the public hanging
of ... toxic
waste dumping, natural resource exploitation, and the conse-
quent degradation of the means of subsistence of indigenous
people. The roles of the state and MNCs in suppressing the
rights of communal ... other members of the Movement
for the Survival of the Ogoni People (MOSOP) in November
1995 in Nigeria. The subsequent detention, torture, and
repression of other members of MOSOP are among the...
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