... Vol 11 No Kluger et al severely injured trauma patients: two parallel randomized, placebo- controlled, double- blindclinical trials J Trauma 2005, 59:8-15 Dereeper E, Ciardelli R, Vincent JL: Fatal ... injured blunt-trauma patients who were included in a prospective, international, double- blind, randomized, placebo- controlled study of rFVIIa [16] and who were diagnosed by the investigators by ... of clinical scenarios [47-51] However, because of its prohemostatic activities, concerns persist over the risk for TE events during its clinical use [52] The previously mentioned randomized, controlled...
... Study design This study was an investigator-initiated, randomized, multi-center, double- blind, parallel-group, placebo- controlled, phase clinicaltrial It focused on the potential of Swedish snus ... [21,22] The main strength of this trial was the double- blind, placebo- controlled design although the protocol did not include procedures to assess the success of the blinding The main weakness was ... Brussels; 2008 doi:10.1186/1477-7517-8-25 Cite this article as: Joksić et al.: Randomized, placebo- controlled, double- blindtrial of Swedish snus for smoking reduction and cessation Harm Reduction...
... analysis of a 13-week, randomized, double- blind, placebo- controlled, multicenter study of three paliperidone palmitate fixed doses in subjects with Page of 10 schizophrenia (ClinicalTrials.gov: NCT00590577; ... 13 Lauriello J, Lambert T, Andersen S, Lin D, Taylor CC, McDonnell D: An 8week, double- blind, randomized, placebo- controlled study of olanzapine long-acting injection in acutely ill patients with ... a potential long-acting treatment for patients with schizophrenia Results of a randomized, double- blind, placebocontrolled efficacy and safety study Int J Neuropsychopharmacol 2010, 13:635-647...
... has been studied in several randomized, double- blindcontrolled trials using various dosing regimens [9-14] A recently completed phase trial was the first placebo- controlled study to assess paliperidone ... 234 mg on Day followed by 39 or 234 mg on Day Methods Design A 13-week double- blind, randomized, placebo- controlled phase trial (NCT#00590577) was conducted from March 2007 to March 2008 at 72 ... post-hoc analyses of a large, doubleblind, placebo- controlledtrial The question of when clinicians and patients can anticipate an improvement in symptoms is integral to clinical decision-making,...
... This was a post hoc analysis of data from an 8-week, randomized, double- blindtrial comparing multiple dosing regimens of olanzapine LAI with placebo for treatment Ascher-Svanum et al BMC Psychiatry ... volition, and preoccupation Discussion In this post hoc analysis of data from a randomized, double- blind, clinicaltrial of olanzapine LAI for treatment of acute exacerbation of schizophrenia, ... 11 Lauriello J, Lambert T, Andersen S, Lin D, Taylor CC, McDonnell D: An 8week, double- blind, randomized, placebo- controlled study of olanzapine long-acting injection in acutely ill patients with...
... U: Therapy of acute nonpurulent rhinosinusitis with cineole: results of a double- blind, randomized, placebo- controlledtrial Laryngoscope 2004, 114:738-742 Wittmann M, Petro W, Repges R, Dethlefsen ... Anti-inflammatory activity of 1.8-Cineole (Eucalyptole) in bronchial asthma: a double- blindplacebocontrolledtrial Respiratory Medicine 2003, 97:250-256 Juergens UR, Engelen T, Stöber M, Racké ... Maslen TK: Randomised, double- blind, placebocontrolled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial BMJ 2000, 320:1297-130...
... benefit against infections iv impact on growth and safety Methods: This double- blind, placebo- controlledrandomizedclinicaltrial involved 253 infants with a family history of allergic disease ... an effective treatment for eczema in a randomized, double- blind, placebo- controlled study with 54 infants randomized to 5x109 CFU of L rhamnosus GG or placebo twice daily for weeks The most recent ... group (23%) as compared to the placebo group (46%) (Relative risk RR 0.51; 95% confidence interval CI 0.32-0.84) This double- blind, randomized placebo- controlledtrial recruited 132 evaluable...
... This is a three-arm (5-Loxin®, Aflapin® and placebo) , randomized, double- blind, placebo- controlled, single-centre trial conducted over 90 days The trial' s primary objective was to determine the ... tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee: a randomizeddoubleblindplacebocontrolledtrial Phytomedicine 2003; 10: 3-7 Bellamy N, Buchnan WW, Goldsmith CH, Campbell ... Alluri KV, Satish AR, Mishra S, Golakoti T, Sarma KV, Dey D, Raychaudhuri SP A double blind, randomized, placebocontrolled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis...
... experiments in rodents have provided the basis for human clinical trials In a randomized, double- blind, multicenter, and controlled phase II clinicaltrial involving 236 patients with severe active RA, ... other clinical trials within months before enrolment Study design The study was a two-to-one, eight-center, 24-week follow-up, double- blind, double- dummy, randomized, and MTX -controlled trial ... arthritis clinical trials J Clin Epidemiol 1997, 50:757-763 22 Lehman AJ, Esdaile JM, Klinkhoff AV, Grant E, Fitzgerald A, Canvin J: A 48-week, randomized, double- blind, double- observer, placebo- controlled...
... This is a three-arm (two doses of 5-Loxin® and placebo) , randomized, double- blind, placebo- controlled, single-centre trial conducted over 90 days The trial' s primary objective was to determine the ... significant beneficial effect in terms of pain relief in OA [33] In addition, a randomized, double- blind, placebo- controlledtrial [34] showed that 4,000 mg milk protein concentrate per day (Microlactin™; ... tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee: a randomizeddoubleblindplacebocontrolledtrial Phytomedicine 2003, 10:3-7 Bellamy N, Buchnan WW, Goldsmith CH, Campbell...
... Study overview The BOLD study is a multicenter, randomized, doubleblind, placebo- controlledtrial that compared the effects of nebulized albuterol to placebo on donor oxygenation in 500 brain-dead ... large, randomized, clinical trials are feasible It is our hope that experience gained in the BOLD study will stimulate other investigators to test donor interventions in randomized, clinical trials ... Perkins GD, McAuley DF, Thickett DR, Gao F: The beta-agonist lung injury trial (BALTI): a randomized placebo- controlledclinicaltrial Am J Respir Crit Care Med 2006, 173:281-287 24 Mascia L, Pasero...
... tobacco dependence, we conducted a randomized, double- blind, placebo- controlled, phase II study of OROS-MPH at a target dose of 54-mg/day for weeks compared with placebo in 80 adult cigarette smokers ... disorder (ADHD) treatment on smoking cessation intervention in ADHD smokers: a randomized, double- blind, placebo- controlledtrial J Clin Psychiatry 2010 Fagerstrom K, Furberg H: A comparison of the ... include a prospective randomizedplacebocontrolled design We also used well developed behavioral interventions for smokers that we have employed effectively in many other clinical trials of pharmacotherapy...
... (20 total per trial) , for each of dominant and non-dominant passing sides on the first, fifth and twelve familiarisation trials 1st Trial Dominant Non-dominant 5th Trial a 12th Trial 7.3 ± 0.8 ... TC: Oral creatine monohydrate supplementation improves brain performance: a double- blind, placebocontrolled, cross-over trial Proc Biol Sci 2003, 270:2147-50 13 Atassi N, Ratai EM, Greenblatt DJ, ... compared to placebo administration (p < 0.001) In the placebo condition, passing skill performance was found to be superior in the non-sleep deprived than the sleep deprived trial (p < 0.001) Placebo...
... design This was a phase IIa, randomized, double- blind, parallel-group, placebo- controlled study conducted at 70 investigative sites in 16 countries around the world (clinicaltrials.gov study number ... Fluticasone furoate (FF) is a novel long-acting inhaled corticosteroid (ICS) This double- blind, placebo- controlledrandomized study evaluated the efficacy and safety of FF 200 mcg or 400 mcg once ... Efficacy in asthma of once-daily treatment with fluticasone furoate: a randomized, placebo- controlledtrial Ashley Woodcock*1, Eric D Bateman2, William W Busse3, Jan Lötvall4, Neil G...
... pulmonary artery hypertension in patients undergoing mitral valve surgery: a prospective, randomized- controlledtrial Acta Anaesthesiol Scand 2008, 52:65-72 Olschewski H, Rose F, Schermuly R, Ghofrani ... inotropic effect of PGI2 In clinical studies, such claims were based on load-dependent haemodynamic indices [6,36] In experimental studies conducted in pigs, supraclinical doses of intravenous ... baseline, and 1, 5, 10 and 30 minutes after stopping iloprost /placebo inhalation In the PHT group, measurements at minute after stopping iloprost/ placebo inhalation consisted only of the registration...
... depressed alcoholics A double- blind, placebo- controlledtrial Arch Gen Psychiatry 1997, 54:700-705 Deas D, Randall CL, Roberts JS, Anton RF: A double- blind, placebo- controlledtrial of sertraline ... placebo- controlled, randomizedclinicaltrial J Am Acad Child Adolesc Psychiatry 2002, 41:1205-1215 Emslie GJ, Rush AJ, Weinberg WA, Kowatch RA, Hughes CW, Carmody T, Rintelmann J: A double- blind, ... was a single site, 8-week, double- blind, placebo- controlled study with parallel arms Eligible youths were randomized in approximately equal numbers to receive either placebo or fluoxetine during...
... corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial) : randomised placebo- controlledtrial Lancet 2004, 364(9442):1321-1328 Page 11 of 12 (page ... placebo- controlledrandomized study was designed to assess the effect of attenuating the neuroinflammatory response after TBI by administration of high-dose methylprednisolone [15] The trial was ... other groups *P < 0.05 for TBI_mAb 1379 vs TBI _placebo groups; #P < 0.05 for TBI vs sham groups; **P < 0.05 for TBI _placebo vs TBI_mAb 1379 vs placebo group (unpaired Student's t-test) 7) In...
... (CHD) included in a doubleblindrandomizedclinicaltrial The numbers (n) indicate the number of dogs within each strata and randomized groups (G) = Gold implantation group (P) = Placebo group (R) ... dogs were followed in an open trial for another 18 months Double blinded controlledclinicaltrial over six months Treatment Open clinicaltrial Follow up18 months Completed no of dogs Drop out ... a controlledclinicaltrial of CHD The treatment effect for gold bead implantation is given in the blinded trial versus the open treatment trial Pain signs of canine hip dysplasia Treatment Blinded...
... study was to evaluate the effectiveness of LDD on clinical symptoms of SS in a randomized, double- blinded, placebo- controlledclinical cross-over trial Figure ment Stimulated saliva pH and salivary ... enter the study All the patients were women This was a randomized, double blind, placebo- controlledclinical trial, and the patients were randomized at the baseline Randomization was performed ... Res 1998, 12:12-26 Petrone D, Condemi JJ, Fife R, Gluck O, Cohen S, Dalgin P: A Double- Blind, Randomized, Placebo- Controlled Study of Cevimeline in Sjögren's Syndrome Patients With Xerostomia and...
... stress disorder: a randomized, double- blind, placebocontrolled study J Clin Psychiatry 2007, 68(2):201-6 Lindley SE, Carlson EB, Hill K: A randomized, double- blind, placebo- controlledtrial of augmentation ... these symptoms There is only one double- blind, placebo- controlled study of topiramate as a monotherapy in PTSD Tucker [29] conducted a 12-week, double- blind, placebo- controlled evaluation of topiramate ... worse; 6, much worse; or 7, very much worse Study design This is a 12-week randomized, double- blind, placebocontrolled clinicaltrial that will be conducted at the Federal University of São Paulo Hospital...