r l stine the haunting hour afraid of clowns

Who’s Afraid of ID, A Survey of the Intelligent Design Movement

Ngày tải lên : 01/11/2013, 08:20

... the marks of nonhuman (alien, artiﬁcially intelligent, or supernatural) design (Ratzsch 2001, 118–20). This is the premise of the Search for Extra Terrestrial Intelligence (SETI), of research ... supposing that the complete history of a football team starts with the moment that the coach gathers together the players, thereby ignoring the important work the players had already done. Before Johnson ... practice. For Rea, the problem is that naturalism cannot explain the modal qualities of particular physical objects. For Koons, the problem is that naturalism cannot account for the reliability...

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Tài liệu Báo cáo khoa học: Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina doc

Ngày tải lên : 19/02/2014, 06:20

... heterologous host. The encoded proteins were purified and their kinetic properties characterized. GLD1 catalyses the conversion of d-glyceraldehyde and l- glyceraldehyde to glycerol, whereas GLD2 ... activity with C5 or C6 sugars. We tested d-glyceraldehyde and l- glyceraldehyde individually and observed similar activities; the activity with l- glyceraldehyde was only slightly lower. For d-glyceraldehyde ... enzymes were purified and characterized. We show that one enzyme catalyses the reduction of d-glyceraldehyde and l- glyceraldehyde to glycerol, whereas the other reduces DHA. This is the first report on...

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Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf

Ngày tải lên : 06/03/2014, 09:22

... few other short stretches, the structures were all very similar over the entire polypeptide chain. However, the presence of the ligands signiﬁcantly reduced the length of the disordered regions: ... site residues (including Arg223 and Ser227), either directly or indirectly. Similarly, the 33 ordered residues in the T structure (that are disordered in the N form) are not related to the Tris-binding ... uniﬁed set of procedure for evaluating the quality of macromolecular structure-factor data and their agreement with atomic model. Acta Crystallogr D Biol Crystallogr 55, 191–205. 42 Krissinel E &...

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Báo cáo khoa học: Characterization of a cathepsin L-associated protein in Artemia and its relationship to the FAS-I family of cell adhesion proteins pot

Ngày tải lên : 07/03/2014, 16:20

... found in the cyto- plasm a nd extracellular matrix where they may have regulatory functions, unlike in somatic cells of multicellular organisms where these enzymes are primarily lysosomal and thought ... represent the pI values of the major bands in e and f, while the numbers at the left are the pI values of standard proteins. The arrow at the right represents the pI value of 6.84 calculated for ... Biological Sciences, University of Windsor, Windsor, Ontario, Canada; 2 Department of Molecular Cell Biology, Sylvius Laboratory, Leiden, the Netherlands We reported previously that the major cysteine...

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Báo cáo khoa học: Structural basis for the erythro-stereospeciﬁcity of the L-arginine oxygenase VioC in viomycin biosynthesis docx

Ngày tải lên : 16/03/2014, 02:20

... b-strand (A) parallel to the ﬁrst b-strand, B, of the jelly roll core. The linkage of the fourth (E) and ﬁfth (F) b-strand of the jelly roll fold is built up by an extended insert (Val199–Leu296) consisting ... auto- mated program for molecular replacement. J Appl Crystallogr 30, 1022–1025. 38 Emsley P & Cowtan K (2004) Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr ... form a hydrogen bond and salt bridge with the a-amino group, although the carboxyl group of Glu170 also coordinates the catalytic iron. Furthermore, the carboxyl group of l- arginine forms a salt...

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Báo cáo khoa học: NMR studies on the interaction of sugars with the C-terminal domain of an R-type lectin from the earthworm Lumbricus terrestris pot

Ngày tải lên : 23/03/2014, 04:21

... sugar-binding site because of the num- ber of intermolecular hydrogen bonds and of residues interacting with lactose. Our results agreed well with those from the crystal structure of the complex between ... 6108–6117. 53 Koradi R, Billeter M & Wu ¨ thrich K (1996) MOLMOL: a program for display and analysis of macromolecule structures. J Mol Graphics 14, 51–55. Supporting information The following supplementary ... aggregates of glycopro- tein and glycolipid receptors. Thus, the carbohydrate cross-linking properties of lectins are a key feature of their biological activities [30,43,44]. R- type lectins are reported...

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OMB Report Pursuant to the Sequestration Transparency Act of 2012 (P. L. 112–155) potx

Ngày tải lên : 23/03/2014, 23:21

... this report include those funding as sequestrable discretionary resources. That is because the STA requires for purposes of this report that OMB assume all discretionary appropriations are repeated ... 251A(5), the total reduction of $54.667 billion is allocated pro- portionately between discretionary appropriations and direct spending. The total base is the sum of the FY 2013 revised discretionary ... and classiﬁcations in the report are preliminary. If the sequestration were to occur, the actual results would differ based on changes in law and ongoing legal, budgetary, and technical analysis....

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Báo cáo khoa học: Identiﬁcation in the yeast Pichia stipitis of the ﬁrst L-rhamnose-1-dehydrogenase gene docx

Ngày tải lên : 30/03/2014, 04:20

... harvested before the sugars were utilized, and the crude cell extract was analyzed for l- rhamnose dehydrogenase activity. Cells grown on l- rhamnose as a sole carbon source had an l- rhamnose dehydrogenase ... Marechal LR & Veiga LA (1979) Induction and catabolite repression of L- rhamnose dehydrogenase in Pullularia pullulans. J Bacteriol 138, 55–59. 12 Jeffries TW, Grigoriev IV, Grimwood J, Laplaza ... fractions of plant biomass, such as hemicellulose and pectin. Several microorganisms liv- ing on decaying plant material are able to use l- rhamnose as a source of carbon and energy. There are...

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Báo cáo khoa học: Kininogen-derived peptides for investigating the putative vasoactive properties of human cathepsins K and L docx

Ngày tải lên : 31/03/2014, 07:20

... of extracellular CP may be favored by the increased expression of vacuolar-type H + -ATPase components, which reduces the pH of the pericellular environment of macrophages [20]. This raises the ... France). N a -benzoyl- L -arginine-4-nitroanilide ( L -BAPA) was from Merck KgaA (Darmstadt, Germany). E-64 and phenyl- methanesulfonylﬂuoride were from Sigma-Aldrich (St Quentin le Fallavier, France). Molecular ... National Institute of Health grant, AR46182. C. D. holds a doctoral fellowship from MENRT (Ministe ` re de l Education Nationale, de la Recherche et de la Technologie, France). References 1. Mu ¨ ller-Esterl,...