patient and how would you manage the other causes of irritant or infective balanoposthitis

Báo cáo y học: "Modeling the clonal heterogeneity of stem cells" doc

Ngày tải lên : 13/08/2014, 16:20

... a sampling of values of f11 (the efficacy of the first treatment for the first clone, on the x axis The results for various values of f22, the efficacy of the second treatment for the second ... in terms of the cellular parameters We now describe the dynamics in terms of the original variables of growth and death rates In the simplest case of a single clone, the survival of the clone ... have revealed conditions which define the order of extinction according to competitive ranking and the richness or diversity of persisting species and the order of extinction Such analyses have usually...

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Báo cáo y học: "Deciphering the molecular machinery of stem cells: a look at the neoblast gene expression profile" pps

Ngày tải lên : 14/08/2014, 20:22

... detection of proliferating cells, such as DjMCM2 [5] and DjPCNA [6], or through BrdU incorporation [7] These cells are scattered throughout the parenchyma with the exception of the anterior end of the ... samples was performed according to the method of Eisen and coworkers [20] Gene log2 ratios were average corrected across experimental samples and displayed according to the central method for display ... along the midline anterior to the pharynx (data not shown) The planarian homolog of Sam68 appeared to be mainly expressed in the dispersed neoblasts and only slightly detectable at the level of the...

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Microgel iron oxide nanoparticles for tracking of stem cells through magnetic resonance imaging

Ngày tải lên : 14/09/2015, 08:49

... Jerry Chan for his tireless inspiration, patience and hands-on approach to the guidance of this thesis The overseas collaborators of this study, Professor André Briguet, Dr Olivier Beuf and Dr Claire ... 2007) Astrocytes are the most populous glial cells of the CNS, and they form a major part of the blood brain barrier and provide metabolic support of neurons Upon recognition of foreign antigen with ... Lee for their support of this endeavour Most of all, I would like to thank my wife, Debbie for her love, patience and presence, and God for this opportunity in life Table of Content Table of Content...

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In vitro differentiation of stem cells towards islet like cells

Ngày tải lên : 09/10/2015, 11:18

... diseases such as diabetes and heart disease However, a lot of work remains to be done in the laboratory to understand how to use these cells as a source for cellular therapy of the diseases 1.4.1 Pancreas ... action, and insulin resistance of glucose transport in skeletal muscle and adipose tissue It is the most common form of the disease, accounting for 85-95% of all cases worldwide The risk of developing ... because of its simplicity and convenience However, the work on safety and the efficiency of the therapeutic gene carrying vector is still in progress There are few strategies on in vivo gene therapy,...

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Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"

Ngày tải lên : 25/10/2012, 11:18

... placed on the platform, the background image was taken under the lights of an illuminator http://www.medsci.org Int J Med Sci 2011, Then, the illuminator was turned off, and the image of light ... into the femoral head and stayed in the femoral head for a relatively long time (Figure A-F) The surface of normal femoral head was smooth and round, and the articular cartilage was transparent and ... surface of femoral head The normal femoral head was smooth and round, and the articular cartilage was transparent and glossy (A) After freezing, the femoral head was pale in the absence of normal...

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Báo cáo y học: "Low temperature tolerance of human embryonic stem cells"

Ngày tải lên : 31/10/2012, 16:57

... humidity and CO2 balance For the 4oC and 25oC exposure groups, the 6-well culture plates were sealed at the sides with parafilm (for minimal evaporation), and placed in either a 4oC refrigerator, or ... obtained for the unexposed control prior to exposing the rest of the culture dishes to low temperature (see Table 1) Table The majority of hESC survived after prolonged durations (24h and 48h) of exposure ... like the embryos from which they originated Hence, the first few reported studies [7, 8] on the establishment of new hESC lines emphasized the use of temperature-heated stage and pre-warmed and...

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Tài liệu Báo cáo khoa học: Expression and secretion of interleukin-1b, tumour necrosis factor-a and interleukin-10 by hypoxia- and serum-deprivation-stimulated mesenchymal stem cells Implications for their paracrine roles ppt

Ngày tải lên : 18/02/2014, 04:20

... stimulatory signal in order to secrete IL-1b and TNF-a Hypoxia ⁄ SD induces the transcription and secretion of IL-10 Because of the lack of secretion of the inﬂammatory cytokines IL-1b and TNF-a ... [3H]-thymidine and [3H]-proline incorporation under normoxic or hypoxic culture conditions To further clarify the molecular mass range of important active factors in the MSCs-CM, the medium was ... SD in the presence or absence of LPS for the indicated number of h *, nonspeciﬁc band (C) The results of ELISA analysis of supernatants from MSCs after hypoxia ⁄ SD stimulation for 12 h in the...

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Báo cáo khoa học: Recruitment of transcription complexes to the b-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells docx

Ngày tải lên : 07/03/2014, 12:20

... for the HS4 core enhancer (HS4), a region 5¢- to HS3 (5¢HS3), the core of HS3 (HS3), a region flanking HS2 and HS3 (3 ⁄ flank), the core of HS2 (HS2), a region downstream of HS2 (3¢HS2), and the ... dimethylation of H3K4 and recruitment of RNA Pol II and TBP to the LCR occurs before activation of any of the globin genes The presence of H3 dimethylated at K4 indicates that these elements ... occur independently of the recruitment of any lineage-specific transcription factors such as PU.1 Furthermore, they observe the presence of components of the TFIID complex (TAF 10 and TBP) at this...

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Stem CELLS and the FUTURE OF REGENERATIVE MEDICINE pdf

Ngày tải lên : 15/03/2014, 09:20

... marrow or the brain, in the adult body They can renew themselves in the body, making identical copies of themselves for the lifetime of the organism, or become specialized to yield the cell types of ... of the authors and not necessarily reflect the views of the organizations or agencies that provided support for the project Library of Congress Cataloging-in-Publication Data Stem cells and the ... Sciences, the National Academy of Engineering, and the Institute of Medicine The members of the committee responsible for the report were chosen for their special competencies and with regard for appropriate...

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Atlas of Human Pluripotent Stem Cells doc

Ngày tải lên : 22/03/2014, 09:20

... The exploration and realization of the incredible potential of these pluripotent stem cells for studying the fundamentals of early human development and organogenesis, for cellbased therapy and ... facilitate the realization of the enormous potential of human pluripotent stem cells and shorten the path from the bench to the bedside We are grateful for the generous support of the Technion’s ... presenting the protocols and morphology of cells cultured on mouse embryonic ﬁbroblasts and on foreskin ﬁbroblasts, and the culturing of cells in feeder-free conditions Taken together, the information...

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Báo cáo khoa học: Epigenetics: the study of embryonic stem cells by restriction landmark genomic scanning pptx

Ngày tải lên : 23/03/2014, 07:20

... status of the T-DMRs [9] The DNA methylation profile of 247 T-DMRs was identified as a unique code for the cell or tissue [3,4] Considering that there are more than 15 000 CpG islands in the mouse ... passages and culture conditions, such as the existence of serum or feeder-layer, affected neither morphology nor expression of cell markers, these parameters changed the DNA methylation profile of human ... hypermethylated loci and repetitive sequences Analysis of the DNA methylation profile for therapeutic use of human ES cells in regenerative medicine The potential use of human ES cells in the field of regenerative...

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Báo cáo khoa học: A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells doc

Ngày tải lên : 30/03/2014, 04:20

... 0.0064 a Of the genes analyzed, the GO biological process is known for 739 up-regulated genes and 215 down-regulated genes Others are unknown b Of the genes in the mother population, the GO biological ... known for 12 441 Others are unknown c The signiﬁcance of the appearance of the GO term (biological process) in the up-regulated and down-regulated genes was calculated as a P value by the software ... Health, Labor and Welfare of Japan, a grant from the Japanese Health Sciences Foundation, and a grant for research fellowships from the Japanese Society for the Promotion of Science for Young Scientists...

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differentiation of embryonic stem cells

Ngày tải lên : 11/04/2014, 00:32

... pursued The ﬁnal screening procedure is use of FCS samples for the production of MEDII and formation of EPL cells in adherent culture The methods for production of MEDII and formation of EPL cells ... EBs The purpose of this chapter is to discuss, at a technical level, the formation and use of EPL cells, including methodologies for further diﬀerentiation of EPL cells to the mesodermal or ectodermal ... Academic Press who organized the assembly of this and hundreds of other volumes of Methods in Enzymology over several decades PAUL M WASSARMAN GORDON M KELLER Table of Contents CONTRIBUTORS TO VOLUME...

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báo cáo hóa học:" Transplantation of vascular cells derived from human embryonic stem cells contributes to vascular regeneration after stroke in mice" docx

Ngày tải lên : 18/06/2014, 15:20

... we used the term 'eEC' for these ECs in the early differentiation stage We sorted and expanded these eECs in vitro These eECs were cultured in the presence of VEGF and 10% FCS and expanded by ... over the course of 50 seconds and checked the time until the mouse fell off The exercise time (seconds) on the rota-rod for each mouse was recorded just before the experiments (= day 0) and on ... (hESECs+MCs) The cell mixture was composed of almost the same number of ECs and MCs We resorted the VE-cadherin+ cells from these expanded cells to obtain ECs for transplantation (Figure 1) The ECs...

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báo cáo hóa học:" Implantation of neural stem cells embedded in hyaluronic acid and collagen composite conduit promotes regeneration in a rabbit facial nerve injury model" doc

Ngày tải lên : 18/06/2014, 15:20

... supported in part by the grants from the 7042014 of the National Science Foundation of Beijing, China, the 50573044 of the National Natural Science Foundation of China and the 2005CB623905 of the ... factor in the nerve growth factor family of neurotrophins helps support the survival, growth and differentiation of both existing and new neurons and synapses in vivo and ex vivo In the study the supplement ... were used to observe, record, and analyze animal behaviour in terms of signs and extents of muscular atrophy of lips, blink reflex, and ear motion of animals before and 12 weeks after peripheral...

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báo cáo hóa học:" MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells" doc

Ngày tải lên : 18/06/2014, 15:20

... pairs Correlation coefficients of miRNA-target gene pairs The expression of miR-302c and miR-502b and their predicted target genes was analyzed by correlation analysis The distribution of the correlation ... miR-373 induces the expression of E-cadherin and CSDC2 by targeting their promoter region and initiate their expression[73] Another mechanism is that the engagement of miRNA and their targets at ... correlation between some specific miRNAs and their targets The distribution of the correlation coefficients for miR-302c-target genes was shifted toward the negative side compared to that of the...

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báo cáo hóa học:" Human fallopian tube: a new source of multipotent adult mesenchymal stem cells discarded in surgical procedures" potx

Ngày tải lên : 18/06/2014, 15:20

... integrity of the tubal epithelium are of paramount importance for the development of a unique microenvironment required for optimal fertilization and early embryo development They are therefore essential ... transport to the uterus [24] Therefore, based on the experience of our research group in the identification, and characterization of potential sources of adult stem cells [7,10,1215], the aim of ... the high levels of expression of adhesion markers (CD29, CD44 and CD90) and other MSC markers (CD13, CD73, SH2, SH3 and SH4) together with the multilineage differentiation results confirmed the...

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Báo cáo hóa học: " Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects" potx

Ngày tải lên : 18/06/2014, 16:20

... LS, FR, and TEI provided detailed ideas and discussions, and/ or writing of the manuscript NAM and JAJ performed the experiments All authors read and approved the final manuscript Page of 10 18 ... Moores Cancer Center, University of California San Diego and Division of Neurosurgery, University of California San Diego, California, USA Department of Cardiothoracic Surgery, University of ... number of colonies depends on the number of plated cells, normalization of colony number based amount of cells plated was performed twice The coefficient for normalization was calculated from the...

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Báo cáo hóa học: "Future research and therapeutic applications of human stem cells: general, regulatory, and bioethical aspects" ppt

Ngày tải lên : 18/06/2014, 16:20

... establish the safety and efficacy of cell therapy products The greater the understanding of the biology of stem cell self-renewal and differentiation, the more precise the evaluation and prediction of ... by the donor, the research or hospital center, and the principal investigator of the project of an informed consent that explains in detail the potential risks and benefits and informs on the ... cell therapy Since one of the most important applications of cell therapy is replacement of the structure and function of damaged or diseased tissues and organs, avoidance or reduction of rejection...

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