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Báo cáo Y học: Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegans doc

Ngày tải lên : 08/03/2014, 23:20

... deletions infringing on th is side lead to a d ecrease in binding. Constructs 2Â5, 5Â2B and 5Â1 are of particular interest; t he rst two constructs break at amino acid 489 and retain binding to Dys-1, ... dystrophin-associated proteins, and homologous to the C- terminal region of dystrophin. Alpha- dystrobrevin was originally identiﬁed as a molecule that copuriﬁes with nicotinic acetylcholine receptors in sucrose gradients ... transgene in vivo. These r esults are consistent with a model according to which dystrobrevin must bind to dystrophin to be able t o function properly. Keywords: dystrophin; dystrobrevin; nematode; Caeno- rhabditis...

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Tài liệu Báo cáo khoa học: Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress pdf

Ngày tải lên : 18/02/2014, 16:20

... Ischemic preconditioning in rats: role of mitochondrial K(ATP) channel in preservation of mitochondrial function. Am J Physiol Heart Circ Physiol 278, H305–H312. Metabolic gene switching in ... (decreased fatty acids, increased glucose) in female hearts to enhance mitochondrial bio- energetic capacity, conferring protection against oxidative stress. Here, we employed male and female control ... H (2001) Intrinsic diurnal variations in car- diac metabolism and contractile function. Circ Res 89, 1199–1208. 19 Sordahl LA, Besch HR Jr, Allen JC, Crow C, Linden- mayer GE & Schwartz A...

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Reproductive System Structure, Development and Function in Cephalopods with a New General Scale for Maturity Stages pot

Ngày tải lên : 14/03/2014, 16:20

... coelom, and usually a single spawning, occur in octopus of the suborder Incirrata. Octopus zonatus, in which repeated spawning has been observed (Rodaniche, 1984), is an exception. In cuttlefish, mature oocytes accumulate mostly in the coelom but partially in ... small nektonic and planktonic preda- tors. The high abundance of these small short-lived squid indicates that this strategy has enabled them to successfully occupy the micronektonic predator niche. The kinds of reproductive system structure and function (of females) found in living cephalopods are characteristic of ... These differ in their origin and function (Chukchin, 1984). Oviductal glands in octopus secrete an adhesive cement, while those of cuttlefish and squid secrete a light mucous which forms the third egg covering. Nida- mental glands in squid and cuttlefish also differ both in form and...

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Báo cáo khoa học: "From Chunks to Function-Argument Structure: A Similarity-Based Approach" doc

Ngày tải lên : 17/03/2014, 07:20

... assigning functional labels such as subject, object, head, complement, etc. to complete syntactic structures on the basis of pre-chunked input. The evaluation of the algo- rithm has concentrated ... contain any information about the function- argument structure of the chunked phrases. How- ever, once a (more) complete parse structure is created, the grammatical function of each ma- jor constituent ... string yield can operate on both of them indiscriminately. The main routine construct tree in Fig. 5 sepa- rates the list of input chunks and passes each one to the subroutine process chunk in...

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Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc

Ngày tải lên : 18/06/2014, 16:20

... (checkpoint 2) [7]. Coincident with the checkpoint 1 to 2 transition, a switch between regulatory and pro- inflammatory cytokine production occurs: prior to b cell death, a period of Th2-dominated ... Immunologic and clinical outcomes of vaccination with a multiepitope melanoma peptide vaccine plus low-dose interleukin-2 administered either concurrently or on a delayed schedule. J Clin Oncol 2004, ... numbers and functions. Introduction Peripheral immune tolerance requires a finely controlled balance between maintaining tolerance to self-antigens and mounting protective immunity against enteric and invading...

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báo cáo hóa học: " A prospective study of decline in lung function in relation to welding emissions" pdf

Ngày tải lên : 20/06/2014, 00:20

... measures. Forced expiratory volume in one second (FEV 1 ) and forced expiratory capacity (FVC) were recorded in accordance with Ameri- can Thoracic Society guidelines (24). Lung function data were ... decline in lung function according to our Table 3: Full shift average exposure to welding fume particulates measured in air samples collected among 44 randomly selected welders in 1987 in comparison ... estimated to 1.5 to 6.5 mg/m 3 . As opposed to welding fume exposure smoking did signifi- cantly contribute to accelerated decline in lung function. Competing interests The author(s) declare that...

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báo cáo hóa học:" Revision of failed hip resurfacing to total hip arthroplasty rapidly relieves pain and improves function in the early post operative period" pdf

Ngày tải lên : 20/06/2014, 04:20

... debris. Effusions were charcoal coloured in 3 cases and cream coloured in one patient in the absence of infection. Cystic lesions were noted behind the acetabular component in 3 cases but the cup was grossly ... participates in moderate activities. Light occupational work 7 Active Regularly participates in active events such as bicycling, aqua-aerobics. Gardening or working out in the gym once or twice a week. 8 ... arts, skiing, acrobatics, ballet dancing, backpacking and mountaineering. Heavy occupational work. 10 Regularly participates in impact sports as described above Table 2 Patient Demographics Males...

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báo cáo hóa học:" Revision of failed hip resurfacing to total hip arthroplasty rapidly relieves pain and improves function in the early post operative period" pptx

Ngày tải lên : 20/06/2014, 07:20

... reactive lines around the loose stem). A B Figure 5 A comminuted complex intertrochanteric fracture occurring due to the patient falling from his bicycle. The acetabular component was retained in ... debris. Effusions were charcoal coloured in 3 cases and cream coloured in one patient in the absence of infection. Cystic lesions were noted behind the acetabular component in 3 cases but the cup was grossly ... logical to avoid cobalt chrome components in the bearing couple when revising for this indication. While it is too early to comment on the clinical outcomes of these prostheses, the main determinants...

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Báo cáo khoa học: "Relationship of cognitive function in patients with schizophrenia in remission to disability: a cross-sectional study in an Indian sample" pps

Ngày tải lên : 08/08/2014, 23:20

... importance of protective factors that could play a role in the functional outcome of patients in spite of cognitive deficits. Although there is no strong evidence, socio-cultural factors have ... excluded from the participants. All patients in our study were on medica- tions, including typical antipsychotics, anticholinergics and benzodiazepines, known to cause cognitive deficits. Although previous ... relationship between cognitive deficits, functional outcome and the role of socio-cultural variables as protective factors. Competing interests The author(s) declare that they have no competing interests. Authors'...

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Báo cáo sinh học: "Breeding structure of Drosophila buzzatii in relation to competition in prickly pears (Opuntia ficus-indica)" potx

Ngày tải lên : 09/08/2014, 18:22

... also indicate the occurrence of interspecific competition, but some care must be taken with such an interpretation because it is possible that conditions that enhance the ... Sinauer, Massachusetts Weir BS, Cockerham CC (1989) Complete characterization of disequilibrium at two loci. In: Mathematical Evolutionary Theory (ME Feldman, ed), Princeton ... basic ingredient in most genetic models is the existence of crowded conditions within patches (ie, selection is ’soft’, meaning that density regulation occurs within each patch...

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Báo cáo y học: " Alterations in hippocampal serotonergic and INSR function in streptozotocin induced diabetic rats exposed to stress: neuroprotective role of pyridoxine and Aegle marmelose" doc

Ngày tải lên : 10/08/2014, 05:21

... learning occur in association with distinct changes in hippocampal synaptic plasticity due to defects in insulin action in the brain [42]. Treatment with insulin therefore not only corrects hyperglycaemia, but ... Paulose CS: Effect of pyridoxine and insulin administration on brain glutamate dehydrogenase activity and blood glucose control in streptozotocin-induced diabetic rats. Biochimica et Biophysica acta ... the antidiabetic effect in streptozotocin induced diabetes. Quantification of Serotonin Serotonin content was assayed according to Paulose et al. [17]. The cerebral cortex and brain stem of the experimental...

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