oxidative and nitrosative stress in parkinson disease
Psychiatric and Cognitive Disorders in Parkinson’s Disease pptx
Ngày tải lên :
28/03/2014, 22:21
... on both hands, mild rigidity and bradykinesia in the upper limbs,
gait slowness, and mild postural instability. He cried during the interview, and worried
about being unable to continue his work ... pallidotomy
Indications
Advanced disease with rigidity and bradykinesia, and a poor response to antiparkinsonian
medications
Disabling dyskinesias
Severe motor Xuctuations
Painful cramps and severe dystonias
Serious ... the cognitive and emotional side-eVects of
speciWc antiparkinsonian drugs, such as l-dopa, dopaminergic agonists,
amantadine, selegiline, and anticholinergic drugs.
In the eighth, and last, chapter...
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Tài liệu Báo cáo khoa học: The small heat shock proteins and their role in human disease pptx
Ngày tải lên :
19/02/2014, 18:20
... or
unfavorable, depending on the disease. As a case in
point, formation of huntingtin-containing inclusion
bodies in Huntington’s disease encourages cell survival,
whereas monomers and small inclusion bodies ... M & Vierling E (2001) The
expanding family of Arabidopsis thaliana small heat
stress proteins and a new family of proteins containing
a-crystallin domains (Acd proteins). Cell Stress Chap-
erones ... deficient in
desmin, again demonstrating inclusion body construc-
tion independent of intermediate fialments [62]. Inter-
estingly, inclusion body formation is slowed by
aB-crystallin, Hsp27 and HspB8,...
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Báo cáo khoa học: Transcript profiling reveals diverse roles of auxin-responsive genes during reproductive development and abiotic stress in rice pdf
Ngày tải lên :
07/03/2014, 01:20
... crosstalk between auxin and
other plant hormones [21–24]. Our study also shows
that genes involved in cytokinin (e.g. cytokinin-O-
glucosyltransferase, cytokinin dehydrogenase, and
response regulators), ... of growth and development in plants. Sev-
eral recent discoveries in auxin biology, including the
identification of F-box proteins as auxin receptors,
have contributed to our understanding of the ... signaling pathways
[55].
To address whether auxin-responsive genes are also
involved in stress responses in rice, their expression
Transcript profiling of auxin-responsive genes M. Jain and J....
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Báo cáo y học: "NITRIC OXIDE (NO), CITRULLINE – NO CYCLE ENZYMES, GLUTAMINE SYNTHETASE AND OXIDATIVE STRESS IN ANOXIA (HYPOBARIC HYPOXIA) AND REPERFUSION IN RAT BRAIN"
Ngày tải lên :
26/10/2012, 09:07
... synthase. The increased
activities of argininosuccinate synthetase and argininosuccinate lyase suggest the increased
and effective recycling of citrulline to arginine in anoxia, making nitric ... arginine at the site of synthesis.
Arginine is a semi essential amino acid and in CNS, its
availability depends upon: (a) uptake from the circu-
lating arginine and (b) recycling of citrulline ... in brain in anoxia as observed by in-
crease in NOx concentration in this study support the
earlier findings of NO involvement in pathophysiol-
ogy of hypobaric hypoxia in brain (42-43). In this...
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Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
Ngày tải lên :
06/03/2014, 19:20
... PM
2.5
onWATandBATspecificgenesin
different adipose depots. There are several major find-
ings in this study. First, exposure to PM
2.5
resulted in
oxidative stress in BAT. Second, exposure to PM
2.5
induced ... analyzed.
Finally, mitochondrial number was reduced in both
eWAT and iBAT in response to PM
2.5
exposure.
Recent studies have implicated PM
2.5
in in creased adi-
pose inflammation and insulin resistance ... PM
2.5
exposure
induced a marked increase in macroph age (F4/80
+
cells)
infiltration in eWAT. Next, we analyzed the changes in
uncoupling protein 1 (UCP1) in response to PM
2.5
exposure. As shown in Figure...
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Báo cáo khoa học: Calcium, mitochondria and oxidative stress in neuronal pathology Novel aspects of an enduring theme pdf
Ngày tải lên :
07/03/2014, 12:20
... by proteins resi-
ding in both the inner and outer mitochondrial
membrane, that is activated by mitochondrial Ca
2+
overloading and other factors including oxidative stress
[88,89]. In neurons ... neuron. The turning point upon which
the cell looses the ability to buffer the incoming calcium
resulting in an abrupt, sustained and irreversible
increase in [Ca
2+
]
c
, probably coincides with ... calcium
transients during reversible brain ischemia. Exp Brain
Res 104, 462–466.
188 Silver IA & Erecinska M (1992) Ion homeostasis in rat
brain in vivo: intra- and extracellular [Ca
2+
] and [H
+
]in
the...
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Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf
Ngày tải lên :
07/03/2014, 12:20
... protein instability caused
by oxidative stress conditions, are important in deter-
mining the level of Bcp2 protein. Similar results are
observed for genes and related proteins involved in
oxidative ... S
p
peroxidatic cysteine;
X unidentified electron donor; S
R
resolving
cysteine; RSH protein or domain with CXXC
motif (e.g. thioredoxin). In typical 2-Cys, S
p
at the N terminus and S
R
at the C terminus
belong ... resol-
ving cysteine (Cys-S
R
). In typical 2-Cys, S
p
at the N
terminus and S
R
at the C terminus of the protein
belong to different subunits and condense to form an
intersubunit disulfide bond; in...
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