or to be implemented by the firm s offices in overseas markets
Role of poly (ADP ribose) polymerase 1 and copper homeostasis factor, antioxidant protein 1 in the maintenance of genomic integrity
... levels in the brain and other tissues The clinical manifestations arise due to the deficiencies in the activity of the essential cuproenzymes On the other hand, Wilson s disease is caused by a ... exposure to arsenical compounds occurs through both industries and natural sources Although workers involved in industries utilizing arsenical compounds such as in vineyards, ceramics, glass-making, ... with sodium arsenite and radiation The absence of ATOX1 was also responsible for increased levels of ROS as well as DSB sustained by the cells In addition, genes in the DNA damage signalling,...
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Tài liệu Báo cáo khoa học: Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis docx
... proteolysis tion into plasmin in situ However, data linking plasminogen conformations and LBS accessibility to its functional properties such as binding to fibrin and cells, activation on these surfaces ... in inflammatory states As plasminogen activation is involved in several physiological and pathological conditions, the effects of the anti-LBS mAbs on fibrinolysis and plasmin-induced apoptosis ... consequence of the inhibition of plasminogen binding on plasmin formation by fibrin-bound tissue plasminogen activator (t-PA) or by CHO-K1 cells For that purpose, t-PA was first bound to a fibrin surface,...
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Tài liệu Báo cáo Y học: Binding of gelsolin domain 2 to actin An actin interface distinct from that of gelsolin domain 1 and from ADF/cofilin pptx
... similar interface as S1 in addition to binding around the DNAse1 binding site in subdomain of actin The Puius model is attractive in that proposing two actinbinding sites explains why S2 causes oligomerization ... running into S2 is sufficient for severing [41] As this is likely to be brought about by weak F-actin binding by the peptide, and this region is so close to S1 it is probable that the N terminus ... in the absence of Ca21 connects S2 to S3 by wrapping around S1 The position of S2 at the edge of subdomain shortens the distance that S3 has to straddle S2 and S4 Major rearrangements between the...
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An Equilibrium Model of Rare-Event Premia and Its Implication for Option Smirks potx
... affects the investor s portfolio of risks, but not their decision-making process This article begins with a simple yet important question: Could it be that investors treat rare events somewhat ... balancing between risk and return according to the estimated probability law, the investor factors into his decision the possibility that the estimated law for the rare event may not be correct As a ... premiums implicit in these securities: fitting it to one security, the model misses out on the others Conversely, if risk aversion were the only source for the premiums implicit in options, then...
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Báo cáo Y học: Structural and serological relatedness of the O-antigens of Proteus penneri 1 and 4 from a novel Proteus serogroup O72 pptx
... galactose in almost equal amounts as well as 2-amino-2-deoxygalactose All sugars were assigned to the D series using GLC of the acetylated (S) -2-butyl glycosides [14±16] The 13C NMR spectrum of the ... O-antiserum LPS, alkali-treated LPS, and LPS±BSA complexes were obtained from the cross-reactive strains and tested in passive immunohemolysis and enzyme immunosorbent assay (Table 3) In all tests, ... O-antiserum The speci®city of the cross-reactions was con®rmed by precipitation test and inhibition of passive immunohemolysis using various LPS as inhibitors in both homologous alkali-treated LPS/O-antiserum...
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Báo cáo khoa học: Inhibitors of protein phosphatase 1 and 2A decrease the level of tubulin carboxypeptidase activity associated with microtubules pptx
... carboxypeptidase with microtubules is necessary for their detyrosination, the alternative possibility that nonassociated carboxypeptidase also catalyses detyrosination is supported by findings in the present ... microtubules is mediated by its capacity to inhibit protein phosphatases Other phosphatase inhibitors (calyculin A and cantharidin) showed a similar effect on the association (Fig 4) These drugs are structurally ... kinases and phosphatases Then, according to the resulting phosphate content, the carboxypeptidase could coassemble with tubulin in the assembly phase of equilibrium, or associate directly on the...
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báo cáo hóa học:" Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a" pot
... those differentially expressed genes whose expression was increased or decreased to the greatest fold as compared to the healthy subjects Among the 30 genes whose expression was increased to the ... MA) consisting of multiplexed assays that measured up to 16 proteins per well in standard 96 well plates (Table 1) The 64 factors were selected to included hematopoietic factors, factors associated ... was also assessed by flow cytometry and the levels of serum inflammatory factors by ELISA Since G-CSF signals through JAK2 MPD neutrophils were also compared to those of healthy subjects after...
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Báo cáo toán học: "Graphs Associated with Codes of Covering Radius 1 and Minimum Distance 2" ppsx
... permutation of the rows, the columns and the symbols in L corresponds to permuting the symbols in each of the positions in C; permutation on the set {row, column, symbol} corresponds the electronic ... cells in the same row, we choose row as in figure 21 If there are any other empty cells in columns 1,2 or 3, then a cell in row marked as being empty may be filled Thus the other empty cells must be ... equivalent to the code C A × Latin subsquare in L is equivalent to a multicoloured 4-clique in G the OQW-associated graph Main class equivalence [3] of Latin squares corresponds to equivalence in codes:...
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Báo cáo khoa học: "Consequences of an excess Al and a deficiency in Ca and Mg for stomatal functioning and net carbon assimilation of beech leaves" ppt
... isolated chloroplasts from Spinacea oleracea Therefore, if Al reached the chloroplasts of intact plants, it is likely to depress the photosynthetic acivity Beech seedlings exposed to excess Al or Ca-Mg ... nor in Ca and Mg concentrations in the leaves between the two treatments Nevertheless, this result strongly suggests the occurrence of a leaf senescence in +Al–CaMg seedlings This hypothesis ... photosynthesis of the European beech, and ii) to estimate the role of Al-induced nutrient imbalance in potential stomatal disorders Therefore, beech seedlings were submitted to excess Al, to...
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Báo cáo y học: "Thymic function and T cell parameters in a natural human experimental model of seasonal infectious diseases and nutritional burden" potx
... clones within the population For the season of birth analyses, means were compared for those born in the hungry/high infection season versus those born in the harvest/low infection season For normally ... the assault on the immune system of both groups may be the reason for the general distortion of the TCRVß repertoire Significantly, the timing of exposure to environmental stressors may be more ... repertoires in healthy and diseased human tissues analysed by T-cell receptor beta-chain CDR3 size determination: evidence for oligoclonal expansions in tumours and inflammatory diseases Res Immunol...
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báo cáo khoa học: " FCR (Fludarabine, Cyclophosphamide, Rituximab) regimen followed by 90yttrium ibritumomab tiuxetan consolidation for the treatment of relapsed grades 1 and 2 follicular lymphoma: a report of 9 cases" pot
... yields progressively less satisfactory responses than the prior treatment, eventually leading to refractory disease, and the question remains regarding whether the survival of patients with FL is ... this setting of patients, specially at age of 60-75 and earlier in first relapse; further studies will help to clarify the best strategy for incorporating RIT into the treatment algorithm of these ... biopsies and also with FDG-PET, this imaging procedure is useful to evaluate disease extension before treatment and response to RIT in FL A recent study has shown that the post-RIT PET result is...
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Báo cáo y học: "An exploration of how clinician attitudes and beliefs influence the implementation of lifestyle risk factor management in primary healthcare: a grounded theory study" pot
... factors (client case example)1 • Work priority to address SNAP risk factors1 • Confidence to address SNAP risk factors1 • Barriers and enablers to addressing SNAP risk factors in routine work ... the clients presenting problem, and thus clients were unlikely to be receptive to discussing these issues Screening for lifestyle risk factors was also not part of their usual work process, they ... link between risk factor issues and the clients presenting problem For those with a counselling role (such as psychologist and social workers), screening for lifestyle issues was considered to...
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Báo cáo y học: " Molecular characterization of genome segments 1 and 3 encoding two capsid proteins of Antheraea mylitta cytoplasmic polyhedrosis virus" pps
... outer capsid protein which can self assemble into VLPs whereas AmCPV S1 codes for an inner minor capsid protein which may be involved in stabilizing virion structure These studies of capsid assembly ... assemble into capsid and S1 encoded Page of 11 protein remains associated with the capsid to maintain its stability Results and discussion Genetic analysis of AmCPV S1 and S3 AmCPV S1 and S3 ... expression of S1 and S3 of AmCPV in E Coli via bacterial expression vector as well as in insect cells using a baculovirus system and show by functional analysis that S3 encoded protein can self assemble...
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Báo cáo y học: "Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts" docx
... 40 Statistical analysis The Student t test was used for statistical analysis A P value of less than 0.05 was considered significant To assess the normal distribution of our data, we assessed their ... functions of Smads This involves interactions with several proteins, such as Smad ubiquitination regulatory factors (Smurfs), the oncoprotein SnoN, and the multi-domain docking protein HEF1 Proteasomal ... to a synthetic AP-1 site was assessed by electrophoretic mobility shift assay (d) using a specific radiolabeled probe in the presence (+) or absence (-) of anti-Ets or anti-c-Jun antibodies or...
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Báo cáo y học: "Heliox improves pulmonary mechanics in a pediatric porcine model of induced severe bronchospasm and independent lung mechanical ventilation" pdf
... function assessment number Results of PFTs obtained at and are reported as assessment number 1; the results of PFTs performed at and are reported as assessment number 2; the results of PFTs performed ... without the variable biological responses which may affect studies involving separate subjects or different bronchospastic events within the same subject as controls It uses the same small (3.0) sized ... difficult to extrapolate to the clinical setting Studies have shown a variable response to heliox therapy in spontaneously breathing patients with severe bronchospasm It has been suggested that this...
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Báo cáo y học: " A mechanistic model of infection: why duration and intensity of contacts should be included in models of disease spread" ppt
... exposed to infectious organisms Thereby, the transmission probability increases with an increase in the number of infectious organisms to which a susceptible individual is exposed Subsequently, ... individual The proposed mechanistic model is based on the following underlying assumptions: In principle, one infectious organism is sufficient to cause infectious disease This hypothesis has been ... repeatedly supported by various studies against the alternative hypothesis assuming a threshold dose of infectious organisms must be passed to cause infection [19,25,26] Page of 10 (page number not for...
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Báo cáo y học: "A continuum mathematical model of endothelial layer maintenance and senescence" ppsx
... progenitors to senescent cells, in addition to the densities of dead cells and the holes created upon clearing these cells Aging of cells is represented by three mechanisms, namely, losing the ability ... equations Table is a summary of the parameters used in the computer simulations The estimation of these parameters is discussed under the section Methods Figure 1(a) shows the assumed dependence of the ... represents homing of EPCs, and the last term corresponds to filling up holes due to divisions of nonsenescent cells adjacent to holes In all the simulations presented in this paper, we considered...
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The roles of histone deacetylases 1 and 2 in hepatocellular carcinoma
... 1988) Other drugs such as Tamoxifen and Somatostatin have also been tested in clinical trials but results are not satisfactory However, there has been some success in the clinical trial of the drug ... assessment for treatment Tumor staging for HCC is done by tumor/node/metastasis (TNM) staging or Okuda staging system (Lau and Lai, 2008) The TNM system classifies tumors based on the size of the primary ... invasion by inflammatory cells and fibrosis (Thorgeirsson and Grisham, 2002) 1.2 1.2.1 Risk Factors for HCC Hepatitis B and Hepatitis C viruses The dominant risk factor for HCC is infection by...
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Báo cáo y học: "Patients'''' recollections of experiences in the intensive care unit may affect their quality of life" doc
... responsible for stress in our patients This can be explained by the traditionally strong family ties in the Portuguese culture Pain came in fourth place in the ranking of stressors This finding, together ... classified as and as being not stressful and those classified as 3, and as being stressful Table shows the recollection of experiences reported as being more stressful (that is, difficult to endure): ... tube aspiration, nose tube, family worries and pain were the ICU experiences described as being more stressful Neuropsychological consequences in ICU survivors have been described as being related...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25