neuroanatomical dissection of the honey bee brain based on temporal and regional gene expression patterns

RUNX3 acts as an ocogene through a hedgehog dependent pathway in selected human neoplasms

Ngày tải lên : 10/09/2015, 15:50

... and relieves the suppression of SMO, leading to the posttranslational modification of the glioma (GLI) family of zinc-finger transcription factors Subsequently, GLI activates the expression of ... in growth and development The historical classification of cellular genes involved in carcinogenesis is a simple binary system consisting of two classes of genes – the oncogenes and the tumor ... treatment The recognition that the delineation of the SHH signaling pathway may lead to certain cancers and the understanding of the pathway inhibition, have led to the development of potential therapeutic...

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Báo cáo khoa học: MicroRNA-373, a new regulator of protein phosphatase 6, functions as an oncogene in hepatocellular carcinoma pdf

Ngày tải lên : 14/03/2014, 23:20

... 4A) Neither blocking of miR-373 with ASOs nor overexpression of miR-373 had any effect on the intensity of EGFP ﬂuorescence from the vector containing mutations in the region encoding the miR-373 ... Inhibition of PPP6C expression increased HCC cell growth as compared with the control group (Fig 6B–D), which was consistent with the effects of miR-373 overexpression Next, we examined the effects of ... invasion of the cancer cells [19] The function of miR-373 on HCC cells needs to be elucidated in the future The fundamental function of miRNAs is to regulate their targets by direct cleavage of...

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báo cáo hóa học: " Methyl salicylate 2-O-b-D-lactoside, a novel salicylic acid analogue, acts as an antiinflammatory agent on microglia and astrocytes" docx

Ngày tải lên : 19/06/2014, 22:20

... the expression of inflammation-related proteins (iNOS, COX-1, and COX-2) in LPS-activated microglia and astrocytes, and we explored the association of these effects with activation of the NF-B ... regulator of various genes involved in the production of many pro-inflammatory cytokines and enzymes related to the inflammatory process Activation of NF-B is critical for the expression of various ... http://www.jneuroinflammation.com/content/8/1/98 Page of Figure The inhibitory effect of DL0309 on NO/iNOS induced by LPS in glial cells Cells were pre-treated for h with the indicated concentrations (μM) of DL0309, and then...

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Báo cáo y học: "Capnography as an aid in localizing the phrenic nerve in brachial plexus surgery. Technical note" potx

Ngày tải lên : 10/08/2014, 10:20

... end-tidal carbon dioxide (ETCO2) and is one of the standards of monitoring in anesthetic care The authors describe the use of capnography as an aid in the intraoperative localization of the phrenic ... 1/3rd of the posterior border of the clavicular head of the sternocleidomastoid and then curved laterally over the medial 2/3rd of the superior surface of the clavicle The platysma was incised and ... noise, and high recording electrode impedance which may diminish reliability and increase the duration of the procedure.[7] On the other hand, capnography is a routine and mandatory anaesthetic monitoring...

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Báo cáo y học: "Correspondence in relation to the case report "Capnography as an aid in localizing the phrenic nerve in brachial plexus surgery. Technical note." published in May issue of Journal of Brachial Plexus and Peripheral Nerve Injury" potx

Ngày tải lên : 10/08/2014, 10:20

... and duration of stimulus on motor response Anesthesiology 2004, 100:1526-1530 Raj PP, Andres JD, Grossi P, et al.: Aids to localization of peripheral nerves In Textbook of regional anesthesia Edited ... hyperventilation leading to reduction of end tidal CO2 Thus I must admit here that this case report is a little bit inadequate in ruling out other possibilities of diaphragmatic contractions rather than ... is not used They have also mentioned something about progressive reduction in ETCO2 level in subsequent capnogram tracings But they have not given any valid explanation to the cause of this occurrence...

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Báo cáo y học: "Response to comments on "Capnography as an aid in localizing the phrenic nerve in brachial plexus surgery. Technical note"" docx

Ngày tải lên : 10/08/2014, 10:20

... Journal of Brachial Plexus and Peripheral Nerve Injury 2008, 3:21 http://www.jbppni.com/content/3/1/21 With increase in the amplitude of current, there is further increase in the force of diaphragmatic ... further increase in the force of diaphragmatic contraction (akin to hiccups) with additional fall in ETCO2 We hope the response addresses the concerns of the reader Thanking you Hemant Bhagat, Anil ... available free of charge to the entire biomedical community peer reviewed and published immediately upon acceptance cited in PubMed and archived on PubMed Central yours — you keep the copyright BioMedcentral...

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Báo cáo y học: "Ketamine as an adjuvant in sympathetic blocks for management of central sensitization following peripheral nerve injury" pptx

Ngày tải lên : 10/08/2014, 10:20

... degree of reduction in allodynia and prolonged relief after introduction of ketamine in all our patients emphasizes the role of NMDA antagonists in reorganization of plastic changes at the peripheral, ... left arm On initial examination, there was sensory loss in the distribution of medial cutaneus nerve of the forearm without motor deficit He was managed conservatively Within days of the injury ... 3:22 therapy could be started The feeling light headedness persisted throughout the period of infusion He did not report any hallucinations After discontinuation of infusion [12th week], the patient...

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Báo cáo khoa học: " Geographical Information System (GIS) as a Tool in Surveillance and Monitoring of Animal Diseases" potx

Ngày tải lên : 12/08/2014, 15:20

... application The information of the locations of the farms with animal production as well as their production type and herd sizes are collected from these two registries The disease recording system of ... municipalities, and in the veterinary ﬁeld, veterinary districts which mostly consist of one ore more municipalities The themes of veterinary districts were manually created and derived from the themes of the ... interface A goal of the introduction of GIS is to have maps continuously displaying the situation for each of the diseases included in the Norwegian Surveillance Program By the use of the registries...

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Báo cáo y học: " A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for primary isolates of human immunodeficiency virus" docx

Ngày tải lên : 13/08/2014, 05:21

... mRNA and cloned into the expression vector pCX-bsr The expression level of the FPRL1 gene in NP-2/ CD4 cells transfected with it, NP-2/CD4/FPRL1, was determined by RT-PCR mRNA expressions of CCR5, ... to be generated by the low fidelity of its reverse transcription and frequent recombination of the genome [39] Mutation of amino acid sequences in the V3 domain of the Env can give HIV1 the ability ... been reported to bind to the membrane-spanning region of FPRL1 [45] Therefore, we assume that the difference in the binding site between the fMLF peptide and HIV-1 is one of the reasons why the...

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Application of titanium silicide as an interconnect in deep submicron integrated chip manufacturing

Ngày tải lên : 11/09/2015, 14:27

... presented before conclusions on the effects of ramp-up rates on the salicide process Chapter Four presents the effects of silicon substrate amorphization on the kinetics of the reaction between titanium ... calorimetry and X-ray diffraction are used Based on these observations, a hypothesis will be proposed to explain the success of this technique The use of a spike anneal on the formation of titanium ... corresponding to the original wavelength of the incident radiation, plus additional lines to each side of it corresponding to the shorter or longer wavelengths of the altered portion of the light...

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Application of titanium silicide as an interconnect in deep submicron integrated chip manufacturing 2

Ngày tải lên : 17/09/2015, 17:20

... The thermal budget on the ramp-up would be lower than that of the ramp-down Hence, it is reasonable to say that the formation of the TiSi2 film did not stop at the peak of the Page 84 Study of ... calorimeter An exothermic peak corresponding to the formation of the C49-TiSi2 phase has been observed in all cases The activation energy for the formation of the C49-TiSi2 phase was obtained and found ... the new exothermic peak could be due to the formation of Ti5Si3 and Ti5Si4 phases It is believed that the formation of Ti5Si3 reduces the Gibbs free energy of the system prior to the formation...

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Báo cáo khoa học: Identiﬁcation of sodium salicylate as an hsp inducer using a simple screening system for stress response modulators in mammalian cells pptx

Ngày tải lên : 17/03/2014, 10:20

... induced the activation of HSF but not transcription of hsp genes in cells Thus, relatively high doses of SA seemed to be required for the induction of the transcription of hsp genes and the accumulation ... showed that SA induced the activation of HSF, the transcription of hsp genes and the accumulation of Hsps in various mammalian cells and a concomitant increase of thermoresistance of cells Thus, SA ... effects of the SA-activated HSF on the induction of transcription of hsp genes Hsps are suggested to play important roles in the acquisition of resistance of cells against various forms of stress...

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The Art of Public Speaking cylinder, piston, water, and fire, is the steam−engine in its most elementary form. For a steam−engine may be defined as an apparatus for doing work by means of heat applied to water; and since raising such a weight as the pisto

Ngày tải lên : 08/08/2012, 17:20

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USING BRAND AS AN EFFECTIVE WEAPON TO COMPETE IN THE MARKET: A CASE STUDY OF NHAT LINH COMPANY

Ngày tải lên : 13/04/2013, 10:29

... because of the following reasons: • Brands generate choice • Brands simplify decisions • Brands offer quality assurance and reduce risks • Brands help self -expression • Brands offer friendship and ... capabilities of the company; between the company’s inputs into the product and the influences on the consumer perception; between the short-term need to maximize profit and the long-term need to invest and ... understand the following aspects of its territory: • • • • The size and scope of the market; The segment in the market; The players in the market and their positions; The trends in all these areas...

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THE INFORMAL SECTOR IN SOLID WASTE MANAGEMENT IN DEVELOPING COUNTRIES SUSTAINABILITY EFFECTS OF FORMALISATION CONSIDERING HO CHI MINH CITY – VIETNAM AS AN EXAMPLE

Ngày tải lên : 24/08/2013, 18:48

... of the situation in HCMC It includes a description of the general conditions for SWM in HCMC, the description of the formal and informal SWM system and presents examples for the integration of ... Industry, the Ministry of Health and their respective regional departments (cp WATSON, 2004) On the regional level there is a Department of Natural Resources and Environment (DONRE) in each of the ... introduction of high tech equipment and the privatisation of landfills limit their access to waste sources and therefore decimate their profit Hence the traditional conflict between the municipality and...

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Báo cáo " Imperialism of communicative language teaching and possible resistance against it from teachers in Vietnam as an English foreign languages context " doc

Ngày tải lên : 05/03/2014, 12:20

... context I will deal with the teachers’ misconception of CLT, their methodology, the relationship among them, the relationship between teachers and learners, teachers’ training program, and their ... increase the quality of teachers’ profession and their life The paper also helps raise teachers’ awareness of applying CLT There are still risks they have to face inside and outside the classroom The ... ways of doing things, along with whole network of associated educational beliefs and values in response to the characteristic and recurrent problems and circumstances they face in their work” The...

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Báo cáo khoa học: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers Implications for the epilepsy seen in the dementia FENIB ppt

Ngày tải lên : 07/03/2014, 16:20

... 25 °C and 95 °C using a heating rate of °CÆmin)1 at a concentration of 0.7 mgÆmL)1 The second derivative of the resulting data was used to calculate the inﬂection point of the transition and hence ... 22, 30, 46, 52, 70, and 78 h of incubation, respectively top of the gel The rate of polymerization was determined by measuring the reduction in density of the monomeric band Wild-type neuroserpin ... Switzerland; catalogue number 69808) Expression and puriﬁcation of recombinant proteins The Ser52Arg mutation was introduced into the cDNA of human neuroserpin in the pQE81L expression vector...

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Báo cáo " An assessment of healthcare system accessibility of local communities in Yen Chau District, Son La Province " pot

Ngày tải lên : 14/03/2014, 15:20

... analyze the characteristics of the study area, Yen Chau District, in both natural and socio‐economic conditions; secondly, to evaluate the impacts of resettlement activities of the Son ... H’mong people. Agricultural land accounts for 76.13%, non‐agricultural land is 20.38% and non‐used land is 3.49% of total area. In general, socio‐economic condition is not good as comparing with other districts. The local people ... from a certain location” [7]. An accessible location is considered as the site when the efforts to get there is acceptable to the target groups (local communities). Therefore, the concepts and the uses of accessibility ...

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Báo cáo khoa học: Coenzyme A affects ﬁreﬂy luciferase luminescence because it acts as a substrate and not as an allosteric effector pot

Ngày tải lên : 16/03/2014, 23:20

... Effect of the concentration of CoA and dephospho-CoA on the velocity of formation of L-CoA and L-dephospho-CoA (A) and on L-AMP inhibited light production (B) The velocities of formation of L-CoA ... performed The effect of the concentration of CoA and dephosphoCoA on the rate of the thiolytic reaction was determined measuring the rate of L-CoA and L-dephospho-CoA formation, respectively The reaction ... observe the formation of L-CoA (Fig 7) The most obvious explanation for the formation of L-CoA in those conditions was the presence of contaminant CoA in the commercial acetyl-CoA preparation used...

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Thuốc chống viêm ức chế lipooxygenase và cyclooxygenase dùng dự phòng và điều trị ung th- (LOX an COX - inhibitors as adjunctive therapies in the prevention and treatment of cancer) ppt

Ngày tải lên : 20/03/2014, 03:20

... kháng với acid arachidonic qua nhiều chế, nh: - Đẩy acid arachidonic khỏi phospholipd màng - ức chế tổng hợp acid arachidonic từ acid linoleic - Cạnh tranh với acid arachidonic vị trí hoạt hoá ... phospholipid Acid arachidonic (AA) A2 (-) AA cyclooxygenasse NSAID lipooxygenase 5-HPETE PG endoperoxyd H2 [G2] Prostacyclinsynthetase leucotrien A leucotrien B prostacyclin (PGl2) PG-synthetase PG sơ cấp ... squalen nhiều polyphenol khác điều biến đợc chuyển hoá acidchidonic tổng hợp PGE2 , mà ngời ta công nhận tác hại eicosanoid (từ acid arachidonic) gây ung th ruột kết ngời Hơn nữa, PGE2 in vitro kích...

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