need for double blind placebo controlled studies
Báo cáo y học: ":Evaluation of the Patient Acceptable Symptom State in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritis" pptx
... multicentre, double- blind, double- dummy, placebo- controlled, parallel-group, 13-week studies of patients with OA of the knee and of identical design was conducted Methodology for the studies has ... last-observationcarried-forward technique was used For dichotomous variables, the number needed to treat (NNT) (that is, the number of patients needed to be treated with the active treatment rather than placebo for ... values for comparison with placebo in analysis of covariance adjusting for study and baseline < 0.001 versus placebo patient was considered a responder by MCII if his/her change from baseline for...
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Báo cáo y học: " Internet-based treatment for older adults with depression and co-morbid cardiovascular disease: protocol for a randomised, double-blind, placebo controlled trial" ppt
... programs, confidentiality information and contact information for the trial team should potential participants want further information In providing consent, within the online form participants will ... older adults with depression and co-morbid cardiovascular disease: protocol for a randomised, double- blind, placebo controlled trial BMC Psychiatry 2011 11:10 Submit your next manuscript to BioMed ... available for analysis Refer to Table for a list of all outcomes to be assessed Other Outcomes The investigators, analysts, trial manager and all participants will be blinded to treatment allocation for...
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báo cáo hóa học: " Improvement in health-related quality of life after therapy with omeprazole in patients with coronary artery disease and recurrent angina-like chest pain. A double-blind, placebo-controlled trial of the SF-36 survey" ppt
... Byrne C: Esomeprazole for the management of upper gastrointestinal symptoms in patients who require NSAIDs: a review of the NASA and SPACE double- blind, placebocontrolled studies Clin Drug Investig ... 23) 20 mg am + 20 mg pm for weeks Placebo (n = 25) caps am + caps pm for weeks Symptom assessment; completion of the SF-36 Health Survey Placebo (n = 23) caps am + caps pm for weeks Omeprazole (n ... Omeprazole (n = 25) 20 mg am + 20 mg pm for weeks Symptom assessment; completion of the SF-36 Health Survey Figure Diagram of the randomized double- blind, placebo- controlled cross-over study design...
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Báo cáo y học: "A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia" pps
... results) Therefore, a randomised double- blind, placebo- controlled study of higher doses (for example, 20 mg) of tropisetron in patients with schizophrenia using a larger sample will be needed In ... Noroozian M, Karamghadiri N, Ghoreishi A, Jamshidi AH, Forghani S: Added ondansetron for stable schizophrenia: a double blind, placebo controlled trial Schizophr Res 2009, 107:206-212 45 Hashimoto ... versus placebo has the advantage of specificity of action Nonetheless, in order to confirm the role of α7 nAChRs in the treatment of schizophrenia, a randomised double- blind, placebo- controlled...
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Báo cáo y học: "First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled comparison with celecoxib [NCT00267215]" doc
... was a randomized, double- blind, placebo and active comparator controlled, parallel group study conducted in 32 centres in Germany All patients provided written informed consent before study-related ... at days (8.9 for lumiracoxib 400 mg once daily; 4.8 for celecoxib 200 mg twice daily) were comparable with those seen in longer 13-week studies with lumiracoxib and celecoxib (7.5 for lumiracoxib ... knee or hip primary osteoarthritis: a phase II, four-week, multicenter, randomized, double- blind, placebo- controlled trial Arthritis Rheum 2004, 51:549-557 21 Bijlsma JW: Analgesia and the patient...
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Báo cáo y học: " Efficacy and hypnotic effects of melatonin in shift-work nurses: double-blind, placebo-controlled crossover trial" ppt
... randomized, double- blind, placebo- controlled crossover study of shift work nurses: results at baseline and after night melatonin or placebo treatment (N = 86) Mean SD P(vs.baselinea) P(vs.placeboa) ... SOL for subjects being treated with melatonin was significantly lower than the mean SOL for subjects given placebo Furthermore, means for both the subjects given melatonin and those given placebo ... compare the efficacy of melatonin (5 mg) and placebo in the treatment of shift workers with insomnia Methods Study Design We conducted a double- blind, placebo- controlled, randomized crossover trial...
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Báo cáo khoa hoc:" Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren''''s Syndrome: a randomized, double-blind, placebo controlled cross-over study" potx
... randomized, double blind, placebo- controlled clinical trial, and the patients were randomized at the baseline Randomization was performed by use of a computer-generated list, and the drug and placebo ... without significant side effects [22], but further research is needed before the wide use of this drug can be substantiated Therefore a need for effective, safe and practical systemic treatment measures ... was to evaluate the effectiveness of LDD on clinical symptoms of SS in a randomized, double- blinded, placebo- controlled clinical cross-over trial Figure ment Stimulated saliva pH and salivary flow...
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Báo cáo y học: "A randomized, double-blind, placebo-controlled trial to assess the efficacy of topiramate in the treatment of post-traumatic stress disorder" pot
... randomized, double- blind, placebocontrolled study J Clin Psychiatry 2007, 68(2):201-6 Lindley SE, Carlson EB, Hill K: A randomized, double- blind, placebo- controlled trial of augmentation topiramate for ... these symptoms There is only one double- blind, placebo- controlled study of topiramate as a monotherapy in PTSD Tucker [29] conducted a 12-week, double- blind, placebo- controlled evaluation of topiramate ... But not all studies found positive results, Lindley [30] in a double- blind, placebo- controlled study using topiramate as an augmentation therapy in forty Page of (page number not for citation...
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báo cáo khoa học:" Improvement in health-related quality of life after therapy with omeprazole in patients with coronary artery disease and recurrent angina-like chest pain. A double-blind, placebo-controlled trial of the SF-36 survey" docx
... Byrne C: Esomeprazole for the management of upper gastrointestinal symptoms in patients who require NSAIDs: a review of the NASA and SPACE double- blind, placebocontrolled studies Clin Drug Investig ... 23) 20 mg am + 20 mg pm for weeks Placebo (n = 25) caps am + caps pm for weeks Symptom assessment; completion of the SF-36 Health Survey Placebo (n = 23) caps am + caps pm for weeks Omeprazole (n ... Omeprazole (n = 25) 20 mg am + 20 mg pm for weeks Symptom assessment; completion of the SF-36 Health Survey Figure Diagram of the randomized double- blind, placebo- controlled cross-over study design...
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Báo cáo y học: " Efficacy and safety of an antiviral Iota-Carrageenan nasal spray: a randomized, double-blind, placebo-controlled exploratory study in volunteers with early symptoms of the common cold" doc
... and objective The current study was designed as a single centre, randomised, double- blind, parallel group, placebo- controlled comparative survey in subjects with early symptoms of common cold ... and free of particles Verum and placebo nasal sprays were identical in shape, size and colour to allow a double- blind design, and were randomized at the CRO Before administration, the spray was ... Mann-Whitney U-tests for continuous variables and by means of Chi square tests for ordinal or nominal distributed variables Tests between treatment groups were performed by Mann-Whitney U-tests For tests...
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Báo cáo y học: "Phytalgic®, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial" potx
... might be a desirable objective in these high-risk longterm users We therefore performed a randomized doubleblind placebo- controlled clinical trial of this marketed food supplement, on the use of ... design and participants This was a double- blind, randomized, placebo- controlled, parallel-arms clinical trial It was approved by the Regional Bordeaux B Committee for the Protection of Patients, ... written informed consent before random assignment to product or placebo This study was performed according to all national laws and regulations governing the conduct of Clinical Trials It conformed...
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Báo cáo khoa học: "Stratification, Blinding and Placebo Effect in a Randomized, Double Blind Placebo-controlled Clinical Trial of Gold Bead Implantation in Dogs with Hip Dysplasia" doc
... knowledge, Haygarth (1800) performed the first placebo CCT in 1799 and described the placebo effect for the first time Placebo effects are commonly reported in CCT studies where humans are involved ... effect of the drug Other studies of conditioning placebo responses have been performed in animals (Newton & Ehrlich 1969, Riley 1981) However, the prime reason for introducing placebo controls is ... The dogs in the placebo group were thereafter offered a crossover to gold bead implantation, and all dogs were followed in an open trial for another 18 months Double blinded controlled clinical...
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Báo cáo y học: " Onset of relief of dyspnoea with budesonide/formoterol or salbutamol following methacholine-induced severe bronchoconstriction in adults with asthma: a double-blind, placebo-controlled study" pptx
... that budesonide/formoterol is suitable for both maintenance and reliever therapy, i.e without the need for a separate SABA Clinical studies show that use of budesonide/ formoterol for both maintenance ... budesonide/formoterol administration Therefore, the window for recovery was slightly smaller for the combination therapy Previous studies comparing formoterol and salbutamol showed similar effects for ... similar for budesonide/formoterol and salbutamol (3.7 and 3.2 minutes, respectively; p = 0.1977; Figure 5), but significantly longer for placebo (22 minutes; p < 0.0001 for both budesonide/formoterol...
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Báo cáo khoa học: "Dexamethasone to prevent postextubation airway obstruction in adults: a prospective, randomized, double-blind, placebo-controlled study" ppt
... Figure ethasone or placebo critically ill patients receiving injections of dexamCuff leak volumes for (normal saline) before extubation ethasone or placebo (normal saline) before extubation Patients ... 0.05) ethasone or placebo critically ill patients receiving injections of dexamCuff leak volumes for (normal saline) before extubation ethasone or placebo (normal saline) before extubation Patients ... Huet Y: Evaluation of risk factors for laryngeal edema after tracheal extubation in adults and its prevention by dexamethasone A placebo- controlled, double- blind, multicenter study Anesthesiology...
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Báo cáo y học: "The effect of exogenous glucagon-like peptide-1 on the glycaemic response to small intestinal nutrient in the critically ill: a randomised double-blind placebo-controlled cross over study" pot
... Hospital and performed according to the Australian National Health and Medical Research Committee guidelines for the conduct of research involving unconscious persons Written, informed consent ... were studied on two consecutive days, in which they received intravenous GLP-1 or placebo in a randomised, double- blind fashion Twelve hours prior to the study, a naso-duodenal feeding catheter ... at a rate of 1.5 ml/min for Page of (page number not for citation purposes) four hours (i.e t = 30 to 270 min) An arterial blood sample was obtained every 15 minutes for measurement of blood...
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Long-Term Safety and Impact on Infection Rates of Postnatal Probiotic and Prebiotic (Synbiotic) Treatment: Randomized, Double-Blind Placebo-Controlled
... freudenreichii ssp shermanii) or a placebo for weeks before delivery Their infants received the same probiotics with 0.8 g of galactooligosaccharides, or a placebo, daily for months after birth Safety ... Propionibacterium freudenreichii ssp shermanii JS (8 –9 ϫ 109 colony-forming units in each capsule) or a placebo twice daily for weeks before delivery For months after birth, the infants received daily opened ... Infection Rates of Postnatal Probiotic and Prebiotic (Synbiotic) Treatment: Randomized, Double- Blind, Placebo- Controlled Trial Kaarina Kukkonen, MDa, Erkki Savilahti, MD, PhDb, Tari Haahtela, MD,...
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báo cáo khoa học:" Psychometric evaluation of a radio electric auricular treatment for stress related disorders: a double-blinded, placebo-controlled controlled pilot study" pps
... committee approval, and all subjects provided written informed consent A double- blind, randomized and placebo- controlled trial was performed to investigate the effectiveness of REAC auricular ... Psychometric evaluation of a radio electric auricular treatment for stress related disorders: a doubleblinded, placebo- controlled controlled pilot study Health and Quality of Life Outcomes 2010 ... Table PSM Clusters population in group A and B before and after therapy vs placebo therapy (n = 150) —— placebo (n = 50) PSM Clusters Before After Before After Loss of control and irritability n...
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Báo cáo y học: "A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis" ppsx
... Esdaile JM, Klinkhoff AV, Grant E, Fitzgerald A, Canvin J: A 48-week, randomized, double- blind, double- observer, placebo- controlled multicenter trial of combination methotrexate and intramuscular gold ... approach for RA To evaluate the efficacy and safety of CCII in RA patients further, we treated two groups of RA patients with oral CCII or MTX in a randomized, doubleblind, multicenter, and controlled ... Study design The study was a two-to-one, eight-center, 24-week follow-up, double- blind, double- dummy, randomized, and MTX -controlled trial comparing efficacy and safety of CCII and MTX in the treatment...
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Báo cáo y học: "nfluence of atorvastatin on coronary calcifications and myocardial perfusion defects in systemic lupus erythematosus patients: a prospective, randomized, double-masked, placebo-controlled study" docx
... proportions The level for statistical significance was predetermined at P < 0.05 Before the study, an informed consent was obtained from each patient The study protocol conforms to the ethical ... Secom SA, Warsaw, Poland) to atorvastatin (40 mg, in the evening) or placebo group Placebo group received shape and color-matched placebo tablets at the same time The duration of the study was one ... continued for one additional minute after injection Tc-99 m sestamibi SPECT imaging was begun 15 to 30 minutes later On the second day rest examinations were performed SPECT was performed using...
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Báo cáo y học: "A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee" potx
... joint stiffness For power calculations, the estimates for variability and assumed mean changes for each treatment group were based on results from previous placebo- controlled studies of celecoxib, ... statistically significant This is a three-arm (two doses of 5-Loxin® and placebo) , randomized, double- blind, placebo- controlled, single-centre trial conducted over 90 days The trial's primary ... efficacy of AKBA-enriched 5-Loxin® in OA in humans have been published Therefore, in the present double- blind and placebo- controlled clinical study, we sought to evaluate the efficacy and safety...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng 9 tr 25