modeling the similarity structure of values

Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx

Ngày tải lên : 21/02/2014, 15:20

... Molecular modeling of the dimeric structure of LPL Two dimeric model structures of LPL were constructed using INSIGHT II version 2000 on a Silicon Graphics workstation The model structure of the closed ... established Of two possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies of the chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL ... structure of monomeric LPL was duplicated and superimposed on the crystal structure of the horse PL dimer After the energy minimization by setting at iteration of 300 cycles or energy level of...

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Tài liệu Đề tài " The causal structure of microlocalized rough Einstein metrics " pptx

Ngày tải lên : 16/02/2014, 05:20

... take the use of the special structure of the Einstein equations one step further by deriving unexpected regularity properties of optical functions which are essential in the proof of the Main Theorem ... properties of the components of the Riemann curvature tensor Rαβγδ The remaining sections are occupied with the proof of the Asymptotics Theorem We give a detailed description of their content and the ... derivatives of the traceless part of χ A similar observation holds for another null component of the Hessian of the optical function, η The role of the Raychaudhuri equation is taken by the transport...

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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Ngày tải lên : 18/02/2014, 06:20

... in the crystal, and a mixture of monomeric and dimeric forms in solution [18] Therefore, the available structural data suggest Fig Ribbon representation of the overall structure of hACMSD The ... as the amino acid numbers The alternative conformations of the Trp–Met couple can be observed; the arrows indicate the unidirectional movement of the two protein residues upon ligand binding The ... on the hACMSD crystals using the same beamline, clearly indicated the presence of a Zn metal ion bound to the enzyme Analysis of the diffraction data set allowed us to assign the crystal to the...

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Tài liệu Báo cáo khoa học: "Understanding the Semantic Structure of Noun Phrase Queries" pptx

Ngày tải lên : 20/02/2014, 04:20

... name of an intent class For example, the IH of the query “alice in wonderland 2010 cast” is “cast”, which is an attribute name of Movie By issuing the query, the user intends to ﬁnd out the values ... goal of this work is to identify the semantic labels of IMs, i.e., the attribute names they implicitly refer to We use Ac to denote the set of IM semantic labels for the intent class c Other ... for semantic understanding of noun phrase queries Assuming that the intent class c ∈ C of a query is known, we cast the problem of extracting the semantic structure of the query into a joint segmentation/classiﬁcation...

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Tài liệu Báo cáo khoa học: The solution structure of reduced dimeric copper zinc superoxide dismutase doc

Ngày tải lên : 21/02/2014, 03:20

... reported X-ray structure of bovine SOD [32] The structure is also similar to the solution structure of the monomeric mutants with the exception of the significantly better definition of the first part ... determined by the experimental intrahistidine NOEs The presence of the disulfide bridge between Cys57 and Cys146 was checked through SDS/PAGE and through the analysis of the 13C shifts of the Cb of the ... percent of the backbone 13C resonances were assigned and about 86% of the 13C side-chain resonances All the ring protons of the histidines of the active site and of His43 were assigned through the...

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Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

Ngày tải lên : 21/02/2014, 03:20

... the overall structure is shown in Fig 3A The enzyme exists as a dimer of the abc heterotrimer There is a noncrystallographic twofold axis around the center of Fig 3A The structure of an abc heterotrimer ... irradiation [59] Therefore, we believe that the structure reported in this paper is also that of the glycerol dehydrataseÆcob(II)alamin complex The dihedral angle of the northern and southern least-squares ... 4C indicates the comparison of the position of the a-acetamide side chain of pyrrole ring A of the corrin ring in the glycerol dehydratase-bound cobalamin (Fig 4Ca) with those in the diol dehydratase-bound...

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Publicly Funded Agricultural Research and the Changing Structure of U.S. Agriculture doc

Ngày tải lên : 06/03/2014, 15:20

... of further analysis The Structure of Agriculture The structure of agriculture” is a broad phenomenon involving both the characteristics of farms (the system of agricultural production) and the ... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the ... influenced the structure of U.S agriculture and, if so, how The Committee to Review the Role of Publicly Funded Agricultural Research on the Structure of U.S Agriculture was asked to assess the role of...

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Báo cáo khoa học: The crystal structure of NlpI A prokaryotic tetratricopeptide repeat protein with a globular fold potx

Ngày tải lên : 07/03/2014, 16:20

... matches to the consensus the full-length HOP, they act to facilitate the assembly of multichaperone regulatory complexes The structural independence of these TPR domains, and the presence of independent ... Crystal structure of NlpI A B C D Fig Solubility of NlpI constructs and the structure of mature NlpI (A) 10–20% gradient SDS ⁄ PAGE of NlpI expression products, showing the insolubility of the 3-TPR ... as the N-terminus of the mature, 276 residue, membrane-anchored protein [22] The identity of the residue at the +2 position (Ser20) in the mature protein suggests that NlpI is not retained at the...

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Báo cáo khoa học: "Understanding the thematic structure of the Qur’an: an exploratory multivariate approach" pdf

Ngày tải lên : 08/03/2014, 04:22

... other profile in the data set The profiles of G can be summarized by a vector s whose dimensionality is that of the data, and each of whose elements contains the mean of the frequencies for the ... where j is the index to the jth element of s, i indexes the rows of the data matrix F, and n is the total number of rows in cluster G If s is interpreted in terms of the semantics of the matrix ... interpretation of the cluster tree, therefore, is to work through the levels of the tree from the top, constructing and comparing thematic profiles for the subclusters at each level as far down the tree...

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Báo cáo khoa học: Molecular mass of macromolecules and subunits and the quaternary structure of hemoglobin from the microcrustacean Daphnia magna ppt

Ngày tải lên : 16/03/2014, 13:20

... Accordingly, the present data on the molecular mass of the native Hb complex as well as the Hb subunits are inconsistent In addition, there are only two hypothetical models concerning the structure of the ... [2,4,8,11,12,42] offers the chance to relate the structure and function of this interesting molecule The present study has contributed to this approach: (a) the determination of the molecular mass of the ... increase the solubility of proteins [52], as in the case of vitellogenin from the decapod crustacean Cherax quadricarinatus [54] A localization of the pre-A segments in the center of the Hb macromolecule...

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The Economic Structure of Intellectual Property Law pot

Ngày tải lên : 16/03/2014, 15:20

... by the relative values of these uses reverse If the recreational users are numerous, the transaction costs of their buying the right to use the river from the factory may exceed the value of the ... for the original In the case of books and other printed matter, the copier may not be able to match the quality of paper or binding of the original or the crispness of the printing, and there ... restricting the use of the property, and if so this is as much a cost of the property right as the cost of the fence is Suppose the owner of a shopping center does charge for the use of his parking...

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Báo cáo khoa học: Modeling the Qo site of crop pathogens in Saccharomyces cerevisiae cytochrome b ppt

Ngày tải lên : 16/03/2014, 16:20

... monitor the effect of F129L and L275F The mutation L275F is naturally occurring in Phytophothora sp The introduction of these mutations decreased the bc1 activity to 44% of the control AB9 Their ... in presence of 10 lM of each of these compounds but were still sensitive to stigmatellin Interestingly structural studies suggest that the Ca hydrogen Fig Structure of the Qo site The cytochrome ... resistant to QoIs, we monitored the respiratory growth competence of the different constructs in the presence of stigmatellin, which binds in the distal lobe of the Qo site, and myxothiazol, azoxystrobin...

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Báo cáo khoa học: Methods to monitor the quaternary structure of G protein-coupled receptors doc

Ngày tải lên : 16/03/2014, 22:20

... efficiency of transfer is determined both by the orientation of the energy transfer partners and by the distance between them [28] The fact that the efficiency of transfer varies with the 6th-power of the ... expressed as the ratio of the distance ‘r’ separating the donor and the acceptor over the distance resulting in 50% of the maximal efficacy (R0) As indicated by the Forster equation, the efficiency of ¨ ... assessing the effect of ligand-binding on the quaternary structure of the receptors, the possibility that the antibodies could inhibit binding to the receptor also needs to be controlled Finally, the...

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Báo cáo khoa học: "Parsing the Internal Structure of Words: A New Paradigm for Chinese Word Segmentation" doc

Ngày tải lên : 17/03/2014, 00:20

... very complex structures By (3)–(5), the generation of word structures is exactly the same as that of ordinary phrase structures Hence the probabilities of these words can be defined in the same way ... S(s) where R is the root part -of- speech headed by the word r, and S is the suffix part -of- speech headed by s If the head of this word is its suffix, then we can define the probability of w by Pr(w) ... parse tree T , if we denote the set of lexicalized phrase structures in T by C, the set of lexicalized word structures by W, and the set of unknown flat words by F, then the joint probability Pr(T,...

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Báo cáo khoa học: The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster Implications for cellulose synthase complex formation and oxidative stress response potx

Ngày tải lên : 17/03/2014, 03:20

... crystal structure of Anx(Gh1) from cotton emphasizes the high conservation of the unique annexin fold even among the members of the plant subfamily of annexin proteins The fold is comprised of the ... are either distorted or the access of a cation to the site is blocked by the presence of a side chain of a basic residue In case of the IIAB site (Fig 2), the acidic residue acting as the bidentate ... residue in the present structure is somehow halfway between the loop-in and the loop-out position of the bell pepper annexin Fig The three-dimensional structure of Anx(Gh1) (A) The fold of Anx(Gh1)...

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Báo cáo khoa học: "TENSE TREES AS THE "FINE STRUCTURE" OF DISCOURSE" ppt

Ngày tải lên : 17/03/2014, 08:20

... pleased with the result." The processing of the (indexical) LF of a new utterance always begins with the root node of the current tense tree (structure) in focus The processing of the top-level ... traversal of trees and the addition of new tokens is simply and fully determined by the logical forms of the sentences being interpreted The major advantage of tense trees is that they allow ... among E, R and S, but rather by successively taking account of the meanings of the nested pres, futr and perf operators in the LF of the sentence As it happens, each of those operators implicitly...

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Báo cáo Y học: The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider pptx

Ngày tải lên : 17/03/2014, 23:20

... twist of the b sheet of androctonin compared to the two other peptides Despite such differences, the rmsd of the coordinates of the b strands of the three peptides when superimposed on the backbone ... on each side of the sheet reduces considerably the hydrophobicity of the surface of androctonin when compared to the two other peptides (Fig 5) Mode of action The mode of action of the three peptides ... in the headgroup region of the membrane, leading to a decrease of the thickness of the lipid bilayer, and then to (b) an active state, when the peptide penetrates the hydrocarbon core of the...

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Báo cáo khoa học: "TEMPORAL REASONING IN NATURAL LANGUAGE UNDERSTANDING: THE TEMPORAL STRUCTURE OF THE NARRATIVE" docx

Ngày tải lên : 18/03/2014, 02:20

... their mother to fix the tail v-~hveof the windmilL b In the great expanse of the prairie where they lived, the high tower of the windmill was the only real landmark (Worline, 1956:1) Given the conceptual ... events: the tail v~ne broke, mother sent the children to fix it, the children set off walking The temporal focus, Indicated by the past perfect tense, is in the middle of the wallri~g event; the ... progression of events within the same narrative unit The required Inferential work le relatively transparent The event of John's entering the o n c e results in the state of his being in the ofrice:...

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Báo cáo khoa học: The crystal structure of a xyloglucan-speciﬁc endo-b-1,4glucanase from Geotrichum sp. M128 xyloglucanase reveals a key amino acid residue for substrate speciﬁcity potx

Ngày tải lên : 23/03/2014, 05:22

... loop because of deletion of those residues The loop structure is responsible for the exo-activity of OXG-RCBH, and the absence of the loop is associated with endo-activity in XEG Therefore, it ... to the exo-loop of OXG-RCBH The coordinates and structure factors have been deposited in the Protein Data Bank (PDB) (accession code 3A0F) The structure of XEG was compared with those of other ... sides of the cleft are open This result, and those of the previous experiment with loop-deleted OXGRCBH [10], strongly suggest that the basis for the endo activity of XEG is the absence of the...

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Báo cáo khoa học: The crystal structure of human WD40 repeat-containing peptidylprolyl isomerase (PPWD1) pdf

Ngày tải lên : 23/03/2014, 07:20

... 2008 FEBS 2285 Structure of spliceosomal cyclophilin PPWD1 T L Davis et al Fig Structure of PPWD1 and comparison with other Cyp structures (A) The structure of the isomerase domain of PPWD1 is shown ... Acceleration of the cis–trans isomerization of the peptide results in the collapse of these resonances into a single set of peaks (D) Binding, but not isomerization, of the N-terminal peptide of PPWD1 ... described in the literature Further complicating the ﬁeld of Cyp biology is the fact that many of the 17 Cyps annotated in the human genome have not been thoroughly studied in terms of either enzymatic...

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