micrornas transforming growth factor beta1 and tissue fibrosis
báo cáo hóa học:" Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?" pot
Ngày tải lên :
18/06/2014, 15:20
... steatohepatitis and 36 with chronic hepatitis C. All had a biopsy-proven diagnosis.
Measurements: Serum concentrations of transforming growth factor- beta1 and ferritin.
Results: High concentrations of transforming ... (NASH) and also of the severity
of fibrosis in NASH. J Gastroenterol 2007, 42:573-82.
16. Khan R, Sheppard R: Fibrosis in heart disease: understanding
the role of transforming growth factor- beta
1 ... values
and similar in the three groups (P = 0.9), also when adjusted for gender (P = 0.5) and age (P = 0.3).
Conclusion: No difference between serum concentrations of transforming growth factor- beta1...
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- 0
Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx
Ngày tải lên :
09/08/2014, 08:22
... the data and helped to draft the manuscript. YA
obtained consent from patients and collected the samples and
patient data for the study, and participated in the coordination
of the study and writing ... article
Activation of transforming growth factor- β
1
and early
atherosclerosis in systemic lupus erythematosus
Michelle Jackson
1
, Yasmeen Ahmad
2
, Ian N Bruce
2
, Beatrice Coupes
1
and Paul EC Brenchley
1
1
Renal ... calculated low-density lipoprotein levels and increased
carotid IMT, and may contribute to the development of early
atherosclerosis.
Introduction
Transforming growth factor (TGF)-β
1
is the most potent...
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- 0
Báo cáo y học: "β Transforming growth factor-β-induced regulatory T cells referee inflammatory and autoimmune diseases" potx
Ngày tải lên :
09/08/2014, 06:22
... additional factors and/ or cofactors that
secondarily contribute to their function and that may
become prevalent in the absence of TGF-β and/ or if TGF-β
is dysregulated. The identification and intersection ... CD4
+
CD25
+
regulatory T cells can
mediate suppressor function in the absence of transforming
growth factor beta1 production and responsiveness. J Exp
Med 2002, 196:237-246.
12. Chen W, Jin W, Hardegen ... infections and autoimmune diseases. Their
mode of suppression is contact-dependent, antigen-nonspecific and
involves a nonredundant contribution from the cytokine transforming
growth factor (TGF)-β....
- 7
- 311
- 0
Báo cáo y học: " Aging, osteoarthritis and transforming growth factor-β signaling in cartilage" pps
Ngày tải lên :
09/08/2014, 07:20
... this disease,
which includes pathophysiology and joint stability including
biomechanics. The balance between anabolic morphogens and
growth factors and catabolic cytokines is at the crux of the ... and 7). The
Commentary
Aging, osteoarthritis and transforming growth factor-
ββ
signaling
in cartilage
A Hari Reddi
Lawrence J Ellison Center for Tissue Regeneration, University of California, ... cells and extra-
cellular matrix by anabolic morphogens and catabolic cyto-
kines [1]. The aim of this commentary is to place in context a
recent article in this journal of anabolic growth factor, ...
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- 0
Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot
Ngày tải lên :
07/03/2014, 01:20
... & Colicelli J (2008) Integration of
transforming growth factor beta and RAS signaling
silences a RAB5 guanine nucleotide exchange factor
and enhances growth factor- directed cell migration.
Mol ... during transforming growth factor-
beta-induced smooth muscle differentiation. J Biol
Chem 281, 1765–1770.
143 Deaton RA, Su C, Valencia TG & Grant SR (2005)
Transforming growth factor- beta1- induced ... PRK2 and p38 MAPK and the transcriptional
upregulation of smooth muscle-specific genes such as
a-SMA, SM-MHC and SM-22a via the cooperation of
serum response factor, GATA and myosin enhancer
factor...
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- 266
- 0
Báo cáo khoa học: Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor–factor VIIa–factor Xa–tissue factor pathway inhibitor pptx
Ngày tải lên :
17/03/2014, 03:20
... 270) Ó FEBS 2003
Probing the interface between factor Xa and tissue factor
in the quaternary complex tissue factor factor VIIa factor Xa tissue
factor pathway inhibitor
Karin Carlsson
1
, Per-Ola ... formation between factor VIIa (FVIIa) and its
cofactor tissue factor (TF) triggers blood coagulation. The
TF–FVIIa complex activates factor X (FX) to factor Xa
(FXa) and factor IX (FIX) to factor IXa ... complex
between factor VIIa (FVIIa) and its cofactor, tissue factor
(TF). TF–FVIIa is inhibited by tissue factor pathway
inhibitor (TFPI) in two steps: first TFPI is bound to the
active site of factor...
- 7
- 450
- 0
Báo cáo khoa học: Fragile X-related protein FXR1 controls posttranscriptional suppression of lipopolysaccharide-induced tumour necrosis factor-a production by transforming growth factor-b1 doc
Ngày tải lên :
22/03/2014, 21:21
... lipopolysaccharide-induced
tumour necrosis factor- a production by transforming
growth factor- b1
Tarnjit K. Khera
1
, Andrew D. Dick
1,2
and Lindsay B. Nicholson
1,2
1 Department of Cellular and Molecular Medicine, ... anti-inflammatory
cytokine transforming growth factor- b1 (TGF-b1) of
the proinflammatory cytokine TNF-a via the induction
of FXR1 is the focus of this article.
TGF-b1, a member of the large transforming growth
factor- b ... of interferon-gamma (IFN-gamma), IL-10,
IL-12 and transforming growth factor- beta (TGF-
beta) mRNA in synovial fluid cells from patients in
the early and late phases of rheumatoid arthritis
(RA)....
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- 0
Báo cáo y học: Identification of an element within the promoter of human selenoprotein P responsive to transforming growth factor-b ppt
Ngày tải lên :
31/03/2014, 23:20
... arylhydrocarbon
receptor expression by transforming growth factor- b
1
. Mol.
Pharmacol. 59, 716 724.
22. Do
ă
hr, O. & Abel, J. (1997) Transforming growth factor- beta 1
coregulates mRNA expression ... Nature 394, 909–913.
28. Roberts, A.B. & Sporn, M.B. (1990) The transforming growth
factor- bs. In Peptide Growth Factors and Their Receptors I (Sporn,
M.B. & Roberts, A.B., eds), pp. 419–472. ... W. (1998)
Identification and functional characterization of a Smad binding
element (SBE) in the JunB promoter that acts as a transforming
growth factor- beta, activin, and bone morphogenetic protein-
inducible...
- 6
- 361
- 1
transforming growth factor-beta protocols
Ngày tải lên :
11/04/2014, 07:14
... 142: Transforming Growth Factor-
`
Protocols
Edited by: P. H. Howe â Humana Press Inc., Totowa, NJ
Detection of TGF-` in Body Fluids and Tissues
Andrew H. Limper
Introduction
Transforming growth ... D., Moses, H. L., and Holley, R. W. (1984) Growth
inhibitor from BSC-1 cells closely related to platelet type ` transforming growth
factor. Science 226, 705–707.
41. Kojima, S. and Rifkin, D. B. ... the cellular receptor for transforming growth factor type `. Biochemistry 25,
3083–3091.
3. Massagué, J. (1987) Identification of receptors for type-` transforming growth
factor. Methods Enzymol....
- 159
- 331
- 0
báo cáo hóa học: " Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised" potx
Ngày tải lên :
19/06/2014, 22:20
... proliferator-activated
receptor γ ; TGF-β1, transforming growth factor β1, TZD,
thiazolidinedione.
Competing interests
Gary Landreth received a honorarium for a talk given to
Takeda North America in 2003, and received funding
from ... western
blots and development of the morphometric method to
quantitate microglia activation; GL and MH organized
and paid for the synthesis and delivery of the chow con-
taining pioglitazone and ibuprofen. ... patho-
genesis and effects on the ageing and Alzheimer brain. Neurol
Res 2003, 25:611-616.
44. Wyss-Coray T, Lin C, Sanan DA, Mucke L, Masliah E: Chronic over-
production of transforming growth factor...
- 17
- 377
- 0
báo cáo hóa học: " Vascular endothelial growth factor-A and chemokine ligand (CCL2) genes are upregulated in peripheral blood mononuclear cells in Indian amyotrophic lateral sclerosis patients" pot
Ngày tải lên :
19/06/2014, 22:20
... Prabhakar
†
, Chandrika Abburi, Neel K Sharma and Akshay Anand
*
Abstract
Background: We have earlier shown that protein levels of vascular endothelial growth factor- A (VEGF-A) and
chemokine ligand-2 (CCL2) ... endothelial growth factor- A (VEGF-A) is a
dimeric secreted polypeptide that was discovered first in
the VEGF family which also includes placental growth
factor (PLGF), VEGF-B, VEGF-C, VEGF-D and VEGF-E.
VEGF-A ... endothelial growth factor mRNA and
downregulates its expression. J Neurosci 2007, 30:7929-38.
16. Lambrechts D, Storkebaum E, Morimoto M, Del-Favero J, Desmet F,
Marklund SL, Wyns S, Thijs V, Andersson...
- 6
- 271
- 0
Báo cáo y học: "Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees" potx
Ngày tải lên :
09/08/2014, 01:21
... AF:
Cloning and sequence analysis of simian transforming growth
factor- beta cDNA. DNA 1987, 6:239-244.
5. Miller DA, Pelton RW, Derynck R, Moses HL: Transforming
growth factor- beta. A family of growth ... problems and prospects.
Cell Regulat 1990, 1:875-882.
2. Roberts AB, Sporn MB: Physiological actions and clinical
applications of transforming growth factor- beta (TGF-beta).
Growth Factors 1993, ... Transforming growth factor- beta. Mul-
tiple actions and potential clinical applications. JAMA 1989,
262:938-941.
7. Beck SL, Chen TL, Mikalauski P, Ammann AJ: Recombinant
human transforming growth...
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- 314
- 0