lidocaine prilocaine has antimicrobial activity at higher concentrations in the ua159 transformant and is not contraindicative to the antimicrobial activity of minocycline hydrochloride

Báo cáo y học: "Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc" ppsx

Ngày tải lên : 09/08/2014, 14:20

... immunolocalization of asporin in the human disc The objectives of the present study, therefore, were to determine the localization patterns of asporin within the human and sand rat intervertebral disc, and ... shortcoming Page of (page number not for citation purposes) is that we were not able to carry out a complete analysis of the localization of asporin in the aging/degenerating lumbar spine of the sand ... Presence of asporin (a) Localization of asporin in the outer annulus of asporin the human disc Note that there are some cells that not show asporin localization (arrow) (b) The presence of asporin is...

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Tài liệu Báo cáo khoa học: High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine pptx

Ngày tải lên : 20/02/2014, 23:20

... both kcat and bkcat are consistent with titration of the catalytic histidine, H438(440) The persistence of activity in the presence of the protonated form of the catalytic histidine is inconsistent ... ½H2 The term k is the observed rate, kA is the limiting rate at high pH, kH is the rate for singly protonated form, kH2 is the limiting rate at low pH (zero in this case), K2 is the dissociation ... titration that ends at zero activity for the fully protonated histidine, theory predicts that at pH unit below the pKa, only 10% of the histidine is unprotonated and that therefore only 10% of the...

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Báo cáo khóa học: Modulation of activity of NADH oxidase from Thermus thermophilus through change in ﬂexibility in the enzyme active site induced by Hofmeister series anions ppt

Ngày tải lên : 30/03/2014, 13:20

... factor, indicates rigidity and strong binding to the protein matrix Trp47, the only tryptophan residue located in close proximity to the avin cofactor (within 10 A), is almost parallel to the isoalloxazine ... in the presence of perchlorate anions, i.e a decrease in the asymmetry of the tryptophan residue and/ or the avin cofactor in the active site, may result from dissociation of the avin cofactor in ... vulgaris, in the presence of phosphate anions, was interpreted as an increase in the dynamics of the tryptophan residue in the vicinity of the avin cofactor [44] A stronger temperature dependence of...

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Báo cáo khoa học: Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA potx

Ngày tải lên : 30/03/2014, 20:20

... strain This inhibitory effect is not obtained if the NGG codons are located at +7 or if the test gene is not induced by IPTG It was noted, but not analysed further, that cells with the nondrop-off ... which is likely to be one of the reasons for the heat-sensitive phenotype of the mutant [14] Increased heat sensitivity of the pth mutant strain has been used to demonstrate accumulation of peptidyl-tRNA ... termination at some out -of- phase termination codon However, this explanation does not seem to be valid Another possibility would be dropoff of peptidyl-tRNA from the translating ribosome during...

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báo cáo hóa học: " Ambulatory monitoring of activity levels of individuals in the sub-acute stage following stroke: a case series" doc

Ngày tải lên : 19/06/2014, 10:20

... throughout the remainder of the day S3 demonstrated small increases in HR later in the testing session (at approximately hours and of testing), and these elevations in HR were of sufficient duration to ... sufficient intensity to challenge the cardiovascular system to the point of training effect Furthermore, the findings of the current study underscore the need to better understand the nature of the ... little information to indicate the type and intensity of activities that stroke patients are engaged in during the day when not in therapy The activities engaged in outside of structured therapy...

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assess the efficiency of dental plaque control in decay teeth, gingivitis prevention for the 12 years- old pupils at some schools in the suburb of hanoi

Ngày tải lên : 25/07/2014, 13:57

... the intervention controlled the DT according to the age in the IV group - The efficency of gingivitis prevention: After the intervention, the gingivitis rate of IV Group reduced, the rate of gingivitis ... p

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Báo cáo lâm nghiệp: " Pinus pumila growth at different altitudes in the Svyatoi Nos Peninsula (Russia)" pps

Ngày tải lên : 07/08/2014, 10:21

... growing at higher altitudes as well as the faster removal of photosynthate from needles and its translocation to its sinks The increase in the size of the area of the central cylinder indicates ... cameracomputer in the biometrical laboratory of MUAF The primary and secondary structure of stems was described according to photographs We described the histological structure including the number of resin ... caused by an increase in temperatures during the growing season as it is docu107 Fig July temperature for the meteostation in Ust-Barguzin (Russia) Data obtained from the weather data archives...

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Báo cáo khoa học: "Glutamate and GABA concentrations in the cerebellum of novel ataxic mutant Pogo mice" pdf

Ngày tải lên : 07/08/2014, 17:22

... that would substitute for the lost Purkinje cell-input, are not indicated by the present findings using GABA-immunohistochemistry GABAergic innervation density is diminished to one-half in the ... Springer, Berlin/Heidelberg 1988 15 Hawkins, R A., DeJosepf, M R and Hawkins, P A Regional brain glutamate transport in rats at normal and raised concentrations of circulating glutamate Cell Tissue ... relationships to sinusoidal vestibular stimulation of floccular Purkinje cells are greatly distorted and irregular under these conditions making a precise time matching of convergent input onto...

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Báo cáo y học: "Identification of new autoantibody specificities directed at proteins involved in the transforming growth factor b pathway in patients with systemic sclerosis" pot

Ngày tải lên : 12/08/2014, 15:23

... in systemic vasculitis [34] Cofilin is a regulator of actin depolymerisation Cofilin is a major effector of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 1-mediated migration, and ... [2] Therefore, further work is warranted to better determine the disease subset and prognosis for these patients The specification of new autoantibodies could help in understanding the Page of ... fragmentation in this setting, possibly through ischemiareperfusion injury as the potential initiator of the autoimmune process in SSc The combined use of 2-DE and immunoblotting offers an interesting approach...

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Báo cáo y học: "Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock" potx

Ngày tải lên : 13/08/2014, 21:20

... first-order elimination was selected to fit the data Investigated PK parameters included maximal serum concentration (Cmax, calculated by extrapolation of the elimination phase at the end of the infusion) ... (depending on the frequency of administration of the β-lactam) thereafter; these blood-draw time points were chosen as they belong to the elimination phase of all four antibiotics The exact sampling ... beta-lactams Clin Infect Dis 1998, 27:10-22 Williamson R, Tomasz A: Inhibition of cell wall synthesis and acylation of the penicillin binding proteins during prolonged exposure of growing Streptococcus...

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Báo cáo y học: "Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes" pdf

Ngày tải lên : 14/08/2014, 07:21

... RP11-536P16 is to indicate that its orientation is shown as in the database The positions of the seven gaps are shown with the approximate positions of the PWS/AS breakpoint (BP)1 to BP3 The map is divided ... (data not shown) These results close gap and clearly show that the beginning of NT_078094 is directly connected to the beginning of NT_026446 (Figure 4c) One of these contigs is therefore in the ... containing segments P, Y and T, suggesting that this region may exist in both orientations in different individuals Although it is not possible to discriminate between models A and B in the RP11 individual,...

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Some strategic solutions to develop logistics services at Sotrans logistics in the period 2006 to 2010

Ngày tải lên : 24/11/2014, 01:44

... Logistics The new point and application value of the thesis: This thesis is the result for my studying about Logistics matter at some companies in the world, within process of working and studying ... The thesis summarizes and mentions about basic logistics matters and the application of logistics into real situation in our company Application value of the thesis is giving real solutions to ... from this country to another country, from this continent to another continent This brings about many subjects participating into supply chain and Logistics activity has been more expanded The concept...

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Commissural axon pathfinding at intermediate targets in the zebrafish forebrain

Ngày tải lên : 14/09/2015, 10:34

... tissues, including brain, retina, somites, and trunk In our hands, the independent manipulation of the electrodes and the insertion of one electrode into the embryo led to frequent lethality and ... 2000) In general, however, at an anatomical level the evolution of the vertebrate brain has consisted of the elaboration and expansion of anterior structures Thus, there is functional and organizational ... characterized in the embryonic zebrafish To understand the anatomy of this commissure, we examined the commissure in dissected whole mount brains using an anti-acetylated tubulin antibody, which...

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Higher education in the 21st century

Ngày tải lên : 04/12/2015, 00:14

... consumer demands To investigate the ramifications of these changes and identify the steps that institutions are taking to flourish and remain relevant in a new climate, The Economist Intelligence ... pressure to find new sources of income in the wake of financial crises In the US, state governments short of cash have tightened the reins on grants that furnished most academic funding to public institutions ... facilities and maintenance, administration) 38 Increasing student tuition 32 Adding online courses 30 Partnering with private industry 30 Increasing appeal to international students 30 Fundraising/attempting...

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Sustainable development in higher education in the Philippines The case of Miriam College

Ngày tải lên : 16/06/2016, 00:43

... alternatives for government and other practitioners in sustainable development It has the talents and expertise of distinguished professors and other experts It has the information on existing ... appropriate productivity, participatory and democratic processes, and living in harmony 289 within the limits of the carrying capacity of nature and the integrity of creation’’ (Phillipine Council ... delivery of education to see to it that all their graduates will be able to participate in the pursuit of sustainable development in whatever field of specialization they choose In the Philippines,...

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Báo cáo khoa học: Increased susceptibility of b-glucosidase from the hyperthermophile Pyrococcus furiosus to thermal inactivation at higher pressures pptx

Ngày tải lên : 07/03/2014, 03:20

... addition, the band at 1.0 GPa in Fig 5C does not resemble the broad, featureless band typical of an unfolded protein Taken together, these observations suggest that the unfolding at the level of the ... function of the incubation In uence of temperature on enzyme inactivation by pressure treatment The in uence of temperature on the inactivation of pressure-treated samples can be seen when comparing ... [16,17] The downward trend above 127 °C is indicative of the dissociation of the aggregates at higher temperatures, as observed previously in the case of myoglobin and lysozyme [21,23] Thermal...

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Báo cáo Y học: ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity potx

Ngày tải lên : 08/03/2014, 22:20

... side-chain binding site that can accommodate the side-chains of ornithine, glutamate, lysine and arginine, but not, for example, that of a-aminoadipate It is interesting to note that the side chain ... (ORF9) The ÔunnaturalÕ CAS-catalysed hydroxylation of L-N-acetylarginine to (2S,3R)-3-hydroxy-N-acetylarginine is shown boxed Scheme The role of OAT (ARGJ) in the biosynthesis of arginine ORF6 ... in the soy based medium [13] Another OAT in the arginine biosynthesis cluster of S clavuligerus (ARGJ) has also been identiﬁed [35], suggesting that the OAT role of ORF6 is directed towards increased...

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Being Born Under Adverse Economic Conditions Leads to a Higher Cardiovascular Mortality Rate Later in Life: Evidence Based on Individuals Born at Different Stages of the Business Cycle pdf

Ngày tải lên : 17/03/2014, 08:20

... deviation in the national Danish birth rate is not signiﬁcantly related to the business cycle indicator in our birth-year window or in larger windows The same applies to the national rate of twin births ... changes with the cyclical indicator of the business cycle at birth Their data are from the Netherlands and contain the social class of the parents at the moment of birth They conclude that there are ... Funen, or Jutland, where it should be noted that the islands of Lolland and Bornholm are included in Zealand, and Jutland is the only part of the country belonging to mainland Europe), and we also...

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Báo cáo Y học: Barley a-amylase Met53 situated at the high-affinity subsite )2 belongs to a substrate binding motif in the bfia loop 2 of the catalytic (b/a)8-barrel and is critical for activity and substrate specificity pot

Ngày tải lên : 31/03/2014, 08:20

... structure of the AMY2 (top) and TAA (bottom) complexes [16,17] The inhibitors are in green and the arrow indicates the nitrogen (in dark blue) that corresponds to the oxygen of the scissile glycosidic ... and other parts of the binding cleft emphasized the intimate contact in between ba loop and domain B and its importance in activity [15] The activity towards insoluble Blue Starch of seven Met53AMY1 ... only 35% It is proposed that combination of the present mutations and mutations at other subsites can accentuate the suppression of activity for shorter substrates and further develop the enzyme...

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Báo cáo y học: " Human herpesvirus 6 major immediate early promoter has strong activity in T cells and is useful for heterologous gene expression" ppsx

Ngày tải lên : 11/08/2014, 21:21

... MIEp Interestingly, the promoter construct that contained introns and was less active than the promoter containing only intron Further investigation is needed to elucidate the mechanisms involving ... for the promoter activity of 6MIEp (A) To investigate the importance of the NF-Bbinding site for the promoter activity of 6MIEp, a 5’-deletion mutant of the 6MIEp lacking the NF-B-binding site ... three independent experiments is indicated One asterisk indicates that the P value is < 0.05 and two asterisks indicate that the P value is < 0.01 in comparison with HHV-6MIEp-d2 (without intron...

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