... that the impact of low-coverage sequencing on the structure ofthe assembly is considerable Reducing the number of sequence reads from a depth of 7.5× to 5× and 2.5× increases the number of contigs ... on the integrity ofthe genome assembly While reduction of errors at the base level is pertinent to improving the quality of shotgun sequence [44], our pilot study has focused on the impact of ... one or other ofthe two paralogues in the syntenic location In the absence of additional species and a more detailed analysis it is not possible to draw definite conclusions regarding the evolutionary...
... healthcare Thelessons described above exemplify the breadth and depth ofthe information gathered by participants at the KTSI We received a sound understanding ofthe theory and practice of KT and ... end ofthe project to include communications experts to help with the dissemination of findings In the latter, partners are engaged throughout the research process, fromthe development ofthe ... about the importance of relationships, the complexity of interactions, the significance of timing, and the potential for ingenuity and innovation in the field of KT These lessons are important...
... healthcare Thelessons described above exemplify the breadth and depth ofthe information gathered by participants at the KTSI We received a sound understanding ofthe theory and practice of KT and ... end ofthe project to include communications experts to help with the dissemination of findings In the latter, partners are engaged throughout the research process, fromthe development ofthe ... about the importance of relationships, the complexity of interactions, the significance of timing, and the potential for ingenuity and innovation in the field of KT These lessons are important...
... estimate the burden of disease The unit cost of an additional DALY is the measure of an intervention's cost-effectiveness; the lower the number, the greater the value for money offered by the intervention ... serious These reports can be used as a community assessment ofthe magnitude ofthe problem and are indicative ofthe perceptions of women and their health-seeking behavior related to 33 symptoms of ... positive predictive value (the number of true positives diagnosed by the algorithm/number of women treated based on applying the algorithm) The results ofthe application ofthe specificity is less...
... rather on the regions initiating or impairing insertion of a segment in the membrane Therefore, in the case of M8 where the length ofthe M8 recombinant peptide is probably shorter than that of ... Likewise, the secondary structure ofthe phorphorylation domain deduced fromthe model built here using the Ca2+-ATPase as template and that determined directly fromthe amino acid sequence ofthe ... in the center ofthe b-strands forming the Rossman fold and leads to the membrane domain at the top of M4 and M5 (see Fig 4, cavities numbered 1–6) As could be expected fromthe high level of...
... raised the awareness ofthe DNRED and the District Land Registration Office staff, and especially the CLAC members on the importance of land management. Responsibilities ofthe leaders ... times and some meetings had to be held at night so that people could fully participate. LessonsLearned Through the implementation of PFLAP in Quang Ngai, the following lessons have been drawn by DoNRE: • The SC, the DWG and the assigned staff have to manage and direct the implementation ... necessary to restrict the transfer ofthe LOCs from one household to another (because there are tendencies to sell the LOCs by land owners) when people get the LOCs. More importantly, people should not lose their forest land, especially their land use rights. ...
... crucible of fast-changing, fragmentary, and conflicting data Business decision makers are often just as torn between the success of their mission and the welfare of their troops They suffer the same ... second-order effects ofthe breathless coverage they gave the so-called New Economy The Henry Blodgets and Jack Grubmans ofthe world are media creations on a par with the cast of Queer Eye for the Straight ... Will the Bad News End?’’ (BusinessWeek).12 The dates ofthe exhibits on the two sides ofthe gallery were only a few years apart The media, it turns out, have the same short-term focus as the...
... conicting interests because, the market value ofthe rm being the same,1 the strategy of maximizing the value ofthe common equity can be pursued only by minimizing the value ofthe convertibles and ... on the fourth quarter ofthe year that includes the market crisis periods The second pricing exercise focuses on the performance ofthe models on the rst quarter of each year that represents the ... using the data fromthe last three quarters ofthe year and, then, 3904 out -of- sample estimates of ct ^ are generated for the rst quarter (Bottom) The pricing error MSPEt ẳ ct ct ị2 across the...
... literature on the costs of each condition associated with egg consumption The goal ofthe present study is to synthesize what is known about the risks and benefits of eggs and the associated costs The ... case, the midpoint of these extreme values was used as the base case input parameter Results The literature search identified a wide range of estimates for the costs ofthe conditions of interest, ... In the absence of such studies, this analysis represents a reasonable approximation ofthe economic impact of adding one egg daily to the diet This analysis also did not consider the cost of...
... in the hemolymph of several crustaceans has been well known since the beginning ofthe 20th century [34] An evaluation ofthe literature revealed that purification of lectin fromthe hemolymph of ... site ofthe lectin was sialic acid on the surface of erythrocytes The binding specificity of crab lectin Inhibition studies with various sugars was helpful in deducing the binding specificity ofthe ... 70–80% ofthe BSM was coupled collected at a rate of 0.6 mLÆmin)1 The column was washed with HSB until the A280 ofthe effluent was < 0.002 The column was further washed with LSB at °C until the...
... Lessonsfromthe Game of Golf The Course This unique golf course consists of eighteen holes, each one devoted to a principle of management Like any other 18-hole course, there are a number of obstacles ... elements and factors that make up the swing, and even the frequency ofthe swing But then who is the customer? The answer is the ball! This particular customer is perhaps the most demanding, unpredictable, ... to improve their performance—that’s why they play Sharing the golfing experience with others while trying to improve their own game is what the game is all about Why can’t some ofthe same factors...
... Colombo Theater 50 The Jaffna Theater 59 Lessonsfrom Jaffna and Colombo 63 Summary Analysisofthe Impacts of 9/11 upon the LTTE 65 CHAPTER THREE India 69 Preview ofthe ... both parties These observations should also inform the expectations ofthe United States as to the limits ofthe possible within the region Third, the population terrain1 of each of these countries ... context of this report to focus on these groups within the context of Pakistan It is not yet clear whether these militant outfits and their activities should form the subject of study within the...
... Unfortunately, the choice ofthe department often reflects the history ofthe project and its previous entry points, rather than a well thought-out strategy The choice of lead departments to manage the ... assessment at the outset, strategic design decisions, such as the selection of priority beneficiary groups, depend on the degree of verticality ofthe intervention and preferences of donors, rather than ... summarizing key lessonsfromthe nine countries This is followed by an introduction, a synopsis of each case study, and a comparative analysis drawn fromthe country findings The comparative analysis...
... the insurgency in the south and recognized the inseparability ofthe political and military aspects ofthe war The part ofthe war discussed in this paper had three phases: the beginning ofthe ... by the Office ofthe Secretary of Defense, the Joint Staff, the Unified Combatant Commands, the iii iv Money in the Bank: LessonsLearnedfrom Past Counterinsurgency (COIN) Operations Department of ... as the strengths and weaknesses of each side and how they contributed to the outcome ofthe conflict In conclusion, the authors sought to acknowledge thelessonslearnedfrom each conflict and the...
... the insurgency in the south and recognized the inseparability ofthe political and military aspects ofthe war The part ofthe war discussed in this paper had three phases: the beginning ofthe ... by the Office ofthe Secretary of Defense, the Joint Staff, the Unified Combatant Commands, the iii iv Money in the Bank: LessonsLearnedfrom Past Counterinsurgency (COIN) Operations Department of ... as the strengths and weaknesses of each side and how they contributed to the outcome ofthe conflict In conclusion, the authors sought to acknowledge thelessonslearnedfrom each conflict and the...
... mass spectrum ofthe doubly charged ion at m ⁄ z ¼ 660.18 The isotopic distribution ofthe b2 ion (inset) indicates the presence of bromine The MS ⁄ MS spectrum allows assignment ofthe sequence ... immediately adjacent to the N-terminal signal peptide [7,14– 17] The propeptide mediates binding ofthe substrate to the carboxylase and also activates the enzyme The discovery of c-carboxylated conotoxins ... S3) The presence of six cysteinyl residues was confirmed by observation of an average mass increment of 640.5 Da after pyridylethylation ofthe reduced peptides (data not shown) The MALDI-MS of...
... point on the curves is the mean of three independent determinations (SD £ 3%) Influence of membrane thickness on the antibacterial activity ofthe peptides The possibility of modifying the A laidlawii ... the susceptibility of mollicutes to melittin and the LK peptides was independent ofthe amount of cholesterol in the membranes of these bacteria Table Antibacterial activities of LK peptides and ... similar to those of mellitin, LK15(3.6) and Dns-LK15(3.6) were the most efficient ofthe LK peptides for the four types of membranes, i.e independent ofthe membrane thickness Their inhibitory...
... subordinates, their ability to perform their jobs, the clarity of their job responsibilities, the organization ofthe work, the cooperation and cohesiveness ofthe group, the sufficiency of resources ... as well as their attitudes toward the administrator It also depends on the nature ofthe activities, the lines of authority in the organization, the integrity of their work group, and the task ... organization They work at the process of institutional renewal They allow the institution to improve continuously They preserve and revitalize the values ofthe institution They mitigate the tendency of...
... COSY experiment allowed analysisof their spin systems and assignments of their proton resonances The assignment of their corresponding carbons, made by a HMQC spectrum The C-H long-range correlations ... confirmed the location of C-23 carboxyl group The chemical shift at C 76.0 (C-3) is typical for the location of -acetoxy of pentacyclic triterpenoids (Shashi B M et al., 1994) Based on the 1H-1H ... identified by Prof Dr Tran Minh Hoi, Institute of Ecology, Biological Resourses, Vietnamese Academy of Science and Technology (VAST) Voucher specimens (No 2539) are deposited at the herbarium ofthe Institute...
... test ofthe efficacy ofthe revised cut points for passing a subtest was made through Differential Item Functioning analysis within the framework ofthe Rasch model [13] This analysis pooled the ... the data fromthe normal and patient groups where, in the latter case, the first level of education also included a number of illiterate patients The basis ofthe DIF approach lies in the item ... interpretation of DIF, as well as an ANOVA ofthe residuals Thus this DIF based ANOVA analysis is subtly different fromthe distributional analysisofthe ANOVA approach which preceded it, as the latter...