instructors manual ta structure and interpretation of computer programs pdf
Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
Ngày tải lên :
14/02/2014, 18:20
... enriched at
TATA-less promoters and may therefore play a role of
maintaining this class of promoter in an open confor-
mation [196].
Many promoters contain CG islands that form
unstable nucleosomes
The ... roughly divided into (a)
TATA-containing promoters where the TATA is
blocked by a nucleosome which can be disrupted by
regulated factors which activate the gene, and (b)
TATA-free constitutively ... developmental transcription factors HNF3
(FoxA) and GATA-4. Mol Cell 9, 279–289.
237 Hatta M & Cirillo LA (2007) Chromatin opening and
stable perturbation of core histone:DNA contacts by
FoxO1....
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
Ngày tải lên :
14/02/2014, 19:20
... Domain structure of the MAP2-asso-
ciated RasGEF v-KIND and its dendritic tar-
geting via KIND2 domain. (A) Structures of
the v-KIND. KIND1, KIND2, coiled-coil (CC),
RasN and RasGEF domains. Flag-tagged
v-KIND ... neurons.
Fig. S4. Domain structure of MAP2 and the alignment
of v-KIND-binding core (BD) region of MAP2 CD2
domain (702–744 aa) in human, mouse and Gallus
This supplementary material can be found ... shaping neu-
ronal circuits, and also may provide a clue to the
understanding of some MAP2-associated neurodegen-
erative and psychiatric disorders [16,17].
Materials and methods
Animals
Mice (ICR)...
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
Ngày tải lên :
17/02/2014, 19:20
... Shimeta & Jumars,
1991) and the problems of dealing with extremely small particles.
It is reasonable to expect tuning of the size of filtering structures and collect-
ing elements to profitable ... Metabolic theory provides a conceptual basis for predicting,
measuring and understanding the roles of different kinds of organisms in the flux
and storage of elements in ecosystems. The total ... Journal of Experimental Marine Biology
and Ecology, 89, 69–80.
Okamura, B. (1988). The influence of neighbors
on the feeding of an epifaunal bryozoan.
Journal of Experimental Marine Biology and
Ecology,...
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Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
Ngày tải lên :
19/02/2014, 12:20
... representation of the structure of NK-lysin, a saposin-like protein [26]. The N-terminal domain is shown in
blue and C-terminal domain in red. (B) Ribbon representation of the structure of the ... prosegment and total or partial removal of the internal
Fig. 1. Plant aspartic proteinase precursors. Comparison of the amino
acid sequences of representative members of the A1 family of plant
aspartic ... residues of the N-terminal of the mature enzyme and
by the ÔflapÕ. The anchorage of the prosegment and of part
of the N-terminus in the active site cleft is made by ionic
interactions established...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
Ngày tải lên :
19/02/2014, 12:20
... combi-
nation [13–15].
From analysis of single channel conductances obtained
upon coinjection of wild-type and mutant subunits, and
from quantification of radiolabelled a and b subunits, the
stoichiometry ... nAChR
antagonists found in cone snail venoms. Identification of
further selective peptides, together with the investigation
and understanding of their structure- activity relationships,
may start ... Crystal structure of
an ACh-binding protein reveals the ligand-binding domain of
nicotinic receptors. Nature 411, 269–276.
6. Dutertre,S.&Lewis,R.J.(2004)Computationalapproachesto
understand...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
Ngày tải lên :
19/02/2014, 16:20
... that of the
pelC protein.
Mutagenesis of insect AFPs
Analysis of the structures combined w ith i nformation fr om
isoform s equences and mutation experiments may provide
clues to understanding ... Graether and Brian D. Sykes
CIHR Group in Protein Structure and Function, Department of Biochemistry and Protein Engineering Network of Centres of
Excellence, University of Alberta, Edmonton, Alberta, ... AFP isoforms
In addition to in vitro mutations, the comparison of isoform
sequences can d emonstrate which residues are important for
a protein’s function and structure. A list of known i soforms
may...
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Tài liệu Báo cáo khoa học: Complete subunit sequences, structure and evolution of the 6 · 6-mer hemocyanin from the common house centipede, Scutigera coleoptrata pptx
Ngày tải lên :
20/02/2014, 11:20
... to compare structure, and
intra- and intermolecular evolution of hemocyanins from
Myriapoda, Crustacea and Chelicerata.
Materials and methods
Protein biochemistry
Scutigera coleoptrata (Myriapoda, ... subunits
and HcX, plus 6–45 bp of the respective 5Â untranslated
regions and the entire 3Â untranslated regions. The standard
polyadenylation signals (AATAAA) and the poly(A)-tails
of different ... submitted to MALDI-
TOF analysis and assigned to distinct subunits.
Fig. 1. SDS/PAGE and immunoblotting of S. coleoptrata hemocyanin.
About 10 lg of total hemolymph protein (HL) and 3 lgofpurified
hemocyanin...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
Ngày tải lên :
21/02/2014, 15:20
... DSC, of caseins, synucleins and tau, together
with several mutants of a-synuclein and tau that cause
neurodegenerative diseases. The ROA spectra of all these
proteins are very similar to those of ... parts of calciđed
stones known as corpora amylacea has recently been
reported [28]. Such stones form in the mammary gland
during lactation and contain a group of amyloid-staining
peptides that start ... Ó FEBS 2002
and the P301L mutant of human tau 46 is P PII helix. Some
b strand may also be present, but no b sheet.
Caseins, synucleins and tau as rheomorphic proteins
The R OA data clearly s...
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Tài liệu Báo cáo khoa học: "The Structure and Process of Talking About Doing" pdf
Ngày tải lên :
21/02/2014, 20:20
... model of the
role of point of view in problem solving.
SUMMARY
We have reported here a three
pronged approach to
the study of problem solving action and report: I) the
collected of data on ... of data on problem solving and talk about
problem solving, 2) development of a process model of
these behaviors, and 3) use of coding techniques to
extract traces of "critical phenomena" ... efforts on two types of problem solving
phenomena: the changes in the problem solver's
organization of the problem ("point of view"), and
systematic multl-utterance structures used...
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Tài liệu Concepts, Techniques, and Models of Computer Programming pot
Ngày tải lên :
22/02/2014, 06:20
... precise specifications of what programs do.
Like Structure and Interpretation of Computer Programs, by Abelson, Sussman,
& Sussman [1, 2], our book mostly uses the computation-based approach. ... diagram of the lift control system 375
5.6 Notationforstatediagrams 375
5.7 Statediagramofaliftcontroller 377
5.8 Implementationofthetimerandcontrollercomponents 378
5.9 Statediagramofafloor 379
5.10Implementationofthefloorcomponent ... improved versions of Java).
The kernel language approach
Practical programming languages scale up to programs of millions of lines of code.
They provide a rich set of abstractions and syntax. How can...
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Tài liệu Báo cáo Y học: The solution structure and activation of visual arrestin studied by small-angle X-ray scattering pot
Ngày tải lên :
22/02/2014, 07:20
... a displacement of arres-
tin’s C-terminus [29] and/ or changes in the conformation of
certain loops that facilitate R* binding [9].
The structure of arrestin R175Q resembles
that of wild-type arrestin
Replacement ... W. Clay Smith
2
and Paul A. Hargrave
2,3
1
Department of Biochemistry, University of Western Ontario, London, Ontario, Canada;
2
Departments of Ophthalmology and
3
Biochemistry and Molecular Biology ... at the top of the (B) and (C), expressed as a
percentage of the total signal from the detector.
Ó FEBS 2002 Activation of visual arrestin (Eur. J. Biochem. 269) 3805
A twofold noncrystallographic...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
Ngày tải lên :
06/03/2014, 11:20
... 0.08
Percentage of residues in
the most favorable region
of the Ramachandran map
91.1 85.5
Percentage of residues in
disallowed region of the
Ramachandran map
00
Superimposition of the structures ... backbone) of all 24 con-
formers of the NMR families of solution structures of
the closed and open conformers of the C-terminal
domain of human eRF1.
Table S1. Differences in the experimental restraints ... coordinates of the atoms in
Fig. 6. Superposition of the representative NMR open conformer
of the C-domain (red and blue) on the crystal structure [20] of the
complex of human eRF1 (green) and the...
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Báo cáo khoa học: Staphylococcus aureus elongation factor G – structure and analysis of a target for fusidic acid pdf
Ngày tải lên :
06/03/2014, 22:21
... complex structure
with GDP and FA [22], and has been suggested to be
ordered only in the ribosome-bound GTP state, as
Table 1. Summary of crystallographic data and refinement.
Data collection statistics
Resolution ... crystal structures of free
EF-G.
FA resistance mutations
FA binds to EF-G on the ribosome and prevents its
dissociation after GTP hydrolysis and translocation. In
the recent crystal structure of ... new crystal structure of S. aureus
EF-G demonstrates the flexibility of EF-G in the free
state, and provides new details that may be useful in
the design of new and better antibiotics targeting...
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Báo cáo khoa học: Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein doc
Ngày tải lên :
07/03/2014, 00:20
... multiple
amyloidogenic forms and with various ligands bound).
The crystal structures of transthyretin from rat [35],
chicken [36] and sea bream [37,38] have also been
solved. All of these structures demonstrate ... struc-
tures of these proteins, all tetrameric, showed signifi-
cant similarity to the published structures of
transthyretin. By way of example, a comparison of the
structure of S. dublin TLP with the structures ... dublin TLP and zebrafish TLP are found in the flex-
ible portions of strands B and C that protrude towards
the solvent and in the conformation of the long loop
connecting strands D and E [17]....
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