implications and role of antiplatelet agents in primary prevention of cardiovascular disease

Role of hydrogen sulfide in the cardiovascular system implications for treatment of cardiovascular diseases

Ngày tải lên : 01/10/2015, 17:27

... Effect of NaHS on mRNA levels of renin in 2K1C rats 57 2.3.5 Effect of NaHS on cAMP level in the clipped and unclipped kidneys of 2K1C rats 58 2.3.6 Effect of NaHS on BP and renin activity in ... renin-angiotensin system (RAS) 151, attenuation of vascular remodeling 152 and activation of KATP channels 18 1.4 Clinical Significance of H2S Unveiling the protective effects of H2S in preclinical ... mg/kg) In another study, administration of IK-1001 (0.005–0.20 mg/kg intravenously, infused over min) induced an increase in blood sulfide and thiosulfate concentrations over baseline In all...

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Evaluation of employees’ job satisfaction and role of gender difference an empirical study at airline industry in iran

Ngày tải lên : 11/09/2013, 11:44

... determinants of job satisfaction, and methodology adopted Subsequently, the main findings are presented and discussed and finally conclusions and managerial implications of the findings and research ... fell in category of between 40 and 50 years old, and only 2.5 percent of respondents fell in the age category of more than 50 years old In addition, 45.4 percent of respondents were single and ... Methodology The population of this study consists of the employees of private airline companies in Iran which called Airline1, Airline2, and Airline3 We choose only private airlines that have more than...

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Tài liệu Báo cáo khoa học: Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages docx

Ngày tải lên : 19/02/2014, 02:20

... some of these materials (e.g Ne-carboxymethyl-lysines and Ne-carboxyethyl-lysines and pentosidine) being known to accumulate with age on tissue proteins, and at an increased rate in LDL and atherosclerotic ... (1994) Binding and modiﬁcation of proteins by methylglyoxal under physiological conditions A kinetic and mechanistic study with Nalpha-acetylarginine, Nalpha-acetylcysteine, and Nalpha-acetyllysine, ... MF, Klein RL & Virella G (1996) Modiﬁcation of lipoproteins in diabetes Diabetes Metab Rev 12, 69–90 10 Tomkin GH & Owens D (2001) Abnormalities in apo B-containing lipoproteins in diabetes and...

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Báo cáo khoa học: Post-ischemic brain damage: pathophysiology and role of inﬂammatory mediators ppt

Ngày tải lên : 07/03/2014, 03:20

... target (Fig 1) Indeed, IL-1ra reduces brain injury in animal models of cerebral ischemia and, in a recent randomized clinical trial, intravenous administration of recombinant human IL-1ra in patients ... proteoglycan and laminin, but also process a number of cell-surface and soluble proteins, including receptors, cytokines and chemokines [81] Thus, in addition to their physiological roles, such ... K & Gearing A (2001) Immunohistochemistry of matrix metalloproteinases in reperfusion injury in rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures Brain Res...

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Báo cáo khoa học: Mycobacterium tuberculosis ClpC1 Characterization and role of the N-terminal domain in its function ppt

Ngày tải lên : 23/03/2014, 06:20

... additional N-domain, homologous to the N-domains of ClpA or ClpB, and a linker domain homologous to, but half the size of, the linker domain of ClpB [19] The N-terminal region contains two 32-amino acid ... functions like a chaperone in vitro Furthermore, we investigated the role of the N-terminal domain of M tuberculosis ClpC1 in its structure and function Most Clp proteins, including ClpC have been shown ... The Clp proteins in M tuberculosis, like many other bacteria, may also be involved in its pathogenesis and an understanding of 6150 their mode of action could be useful in exploring them as drug...

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INVESTIGATING DIVERSITY IN THE BANKING SECTOR IN EUROPE: THE PERFORMANCE AND ROLE OF SAVINGS BANKS pdf

Ngày tải lên : 29/03/2014, 07:20

... sides, including leading bankers and bankers’ associations like the Institute for International Finance, to rethink the role of the state in the financial system and to reconsider more stringent ... information, incentives and institutions, providing a more favourable view of the possible role of the state in financial markets 35 INVESTIGATING DIVERSITY IN THE BANKING SECTOR IN EUROPE | 33 ... Cartel Office, and in 2007, following the inquiry of the Spanish Competition Commission, fined several savings banks for market-sharing agreements 44 INVESTIGATING DIVERSITY IN THE BANKING SECTOR IN...

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báo cáo hóa học:" Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer" pdf

Ngày tải lên : 20/06/2014, 07:20

... deletion or loss -of- function mutations in the survival of motor neuron (SMN) protein results in SMA [12] Gemin and Gemin are shared components of SMN and miRNAcontaining ribonucleoprotein particles ... overexpression of miR-375 resulted in suppressed glucose-stimulated insulin secretion and its inhibition resulted in enhanced insulin secretion Myotrophin, a protein that has a role in exocytosis, ... up-regulated and were down-regulated It was determined that increased expression of miR-181a, miR-181b, and miR-213 in OVCA cell lines results in resistance to doxorubicin and gemcitabine and increased...

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báo cáo khoa học: "The expression and role of protein kinase C (PKC) epsilon in clear cell renal cell carcinoma" ppt

Ngày tải lên : 10/08/2014, 10:21

... coordinated remodeling of the actin cytoskeleton, regulated assembly, and turnover of focal adhesion [11] Interestingly, PKCε contains an actin-binding domain [12] and promotes F-actin assembly in ... staining scored 0; faint or moderate staining in ≤ 25% of tumor cells scored 1; moderate or strong staining in 25% to 50% of tumor cells scored 2; strong staining in ≥50% of tumor cells scored ... pathologists blinded to clinical data scored PKCε immunohistochemical staining of all sections according to staining intensity and the percentage of positive tumor cells as follows [23,24]: no staining...

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Báo cáo y học: " Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells" doc

Ngày tải lên : 13/08/2014, 09:20

... expression of Cyclin T2a, another Cyclin partner of CDK9, remained largely unchanged by prostratin (Fig 2B), suggesting the presence of Cyclin T2a does not prevent the induced Cyclin T1 from binding ... Figure induces expression of CD69 without promoting cell cycle progression in resting CD4+ T cells Prostratin Prostratin induces expression of CD69 without promoting cell cycle progression in resting ... http://www.retrovirology.com/content/3/1/66 Figure Effects of prostratin on the expression levels of Cyclin T1, Cyclin T2a, and CDK9 Effects of prostratin on the expression levels of Cyclin T1, Cyclin T2a, and CDK9 Cell extracts...

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Báo cáo y học: " Interactions Between Estrogen- and Ah-Receptor Signalling Pathways in Primary Culture of Salmon Hepatocytes Exposed to Nonylphenol and 3,3'''',4,4''''-Tetrachlorobiphenyl (Congener 77)" ppsx

Ngày tải lên : 13/08/2014, 13:20

... through the binding of RNA-binding proteins to target mRNAs that prevent their cleavage by endonucleases [45] Vigilin, or high density lipoprotein-binding protein, is an ubiquitous protein in vertebrate ... time-specific manner, indicating that NP has anti-AhR signalling effects Interestingly, the expression of AhRβ and ARNT showed a different pattern of effect in PCB-77 exposure alone and in combination with ... PCB-77 and NP dose ratios and sequential order of exposure and interestingly influenced by seasonal changes [11] In a recent study, we showed that the partial inhibition of AhR with α-naphthoflavone...

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The Position and role of small and medium enterprises in a national economy – the case of Japan

Ngày tải lên : 01/11/2014, 22:05

... grouping) in relation to big enterprises Role as supporter of innovation and new industry Role as absorber and creator of employment Role of developing and stabilizing the regional economy Role to ... kinh tế khu vực Vai trò để kích hoạt kinh tế thị trường I will explain the role of 1, and in more detail 1: Role as subcontractor and Keiretu (corporate grouping) Trang | 14 Vị trí DN V&N kinh ... technology improvement and personnel training for SMEs A pro-active method of planning and preparations in the design and development phase promotes close sharing, cooperation, and information between...

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Distribution and role of calcium independent phospholipase a2 in the brain

Ngày tải lên : 11/09/2015, 09:58

... 4, resulting in a disruption of the calcium binding domain and loss of both activity domains encoded by exons and The identification of this mutation has important implications in mouse inflammatory ... (“housekeeping”) in cells (Balsinde et al 1995) and play important roles in intracellular signal transduction, but also ensures smooth functioning of the electron transport chain by maintaining the integrity ... propranolol when investigating the roles of iPLA2 in cell growth and signaling (Balsinde and Dennis, 1996) PAP-1 is inhibited by propranolol, which does not inhibit iPLA2 Using a combination of MAFP,...

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The rise and role of tariqa among muslims in singapore the case of the naqshbandi haqqani

Ngày tải lên : 16/10/2015, 11:58

... demands and the important role of agency in religious affiliation Focusing on Chinese religions and Christianity, he explores the reasons for the increasing levels of conversion among Chinese Singaporeans ... relationship of religion and State The study of religion, which focuses on the agency of subjects, is few and far between Following this, observing the increasing individual and group differentiation of ... analysis of tariqa within a cogent theoretical framework is pressing Voll (1994) opines that the surprise in the vitality of Sufism today is “part of a broader surprise involving the continuing influence...

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Tài liệu Changing patterns of cardiovascular diseases and cancer mortality in Portugal, 1980--2010 docx

Ngày tải lên : 15/02/2014, 04:20

... risk of cancer We also observed a decrease in the number of deaths caused by gastro-intestinal diseases, injuries and poisoning, and infectious and parasitic diseases in the last three decades, in ... miscoding can occur mainly because of incorrect diagnoses, incorrect or incomplete death certificates, misinterpretation of ICD rules for coding underlying causes, and variations in the use of categories ... for only 14% and cancer for 8% of the total years of life lost (YLL) in 2004, surpassed by infectious and parasitic diseases, perinatal conditions and unintentional injuries Age-standardized mortality...

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Insight and Control of Infectious Disease in Global Scenario Edited by Priti Kumar Roy potx

Ngày tải lên : 30/03/2014, 22:20

... 2008; Berrington & Hawn, 2007) have been performed for investigation of their role in disease risk 10 Insight and Control of Infectious Disease in Global Scenario Infectious disease has profound ... higher 32 Insight and Control of Infectious Disease in Global Scenario 2.1 Types of vaccine There are basically three ways of making vaccines against infectious diseases, all rely on a level of knowledge ... (LTs) and lipoxins (LXs) are play a role in the generation of appropriate responses to inflammatory disease (Parkinson, 2006) and are involved in the regulation of immune cells and cytokine release...

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Báo cáo hóa học: " Research Article Slotted Gaussian Multiple Access Channel: Stable Throughput Region and Role of Side Information" pdf

Ngày tải lên : 21/06/2014, 23:20

... [5] In this notion, the problem of understanding delay in an informationtheoretic setting remains intractable, since n → ∞ makes all talk of per-bit delay irrelevant A bit, even if it is in the ... coding over noiseless channels in [5]) Our objective is to study the role of this statistical information on the stability of multiuser-queuing system and, in the process, understand the interplay ... state information The codebooks are chosen at the beginning of operation and stay ﬁxed throughout Since (γ1 , γ2 , , γK ) is in the interior of the capacity region, there exists an encoding and...

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Báo cáo y học: "Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis" potx

Ngày tải lên : 09/08/2014, 10:20

... aging, diabetes and renal failure, and at sites of inflammation (by oxidation) [16] Levels of S100 proteins and HMGB1 are increased in both adult and juvenile RA [17], and inhibition of the RAGE ... coronary disease Creatinine clearance (CrCl) was estimated for each patient on the basis of the serum creatinine (SCr) level, age (in years) and ideal body weight (in kg), using the Cockcroft and ... function in RA patients with a normal lipid profile and have additional immunomodulatory and RA disease- modifying benefits, including reduction of CRP levels, serum TNF concentrations and indices of...

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Báo cáo khoa học: " A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients" pdf

Ngày tải lên : 09/08/2014, 10:21

... protecting the skin from desiccation and degradation focus on the lamellar structure of the stratum cornea and maintenance of the lipid bilayers, which requires a combination of external and internal ... to keep skin soft, smooth, and supple [2] Proactive treatment to prevent radiation dermatitis is directed at reducing the drying effect of radiation on the skin and involves instructing patients ... patient of skin dryness, softness, satisfaction, roughness, and smoothness and examiner assessment of skin dryness, erythema, and peeling Methods This study was approved by the St Jude Institutional...

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Báo cáo y học: "Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in patients with lupus nephritis: a prospective longitudinal study" pdf

Ngày tải lên : 09/08/2014, 14:22

... significant actinin DNA (dsDNA), (b) nucleosomes and α-actinin and (c) dsDNA and αCorrelation between binding to (a) nucleosomes and double-stranded DNA (dsDNA), (b) nucleosomes and α-actinin and (c) ... Figure Figure DNA and α-actinin Baseline binding data for binding to nucleosomes, double-stranded DNA and α-actinin On each graph, absorbance ratios of the 30 normal controls and the 16 patients ... score for renal disease activity This composite score was defined using measurements of urine PCR and serum albumin and creatinine Complete renal remission was defined as follows: PCR of not more...

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